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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to hypoxia
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Accession:GO:0071456 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
Comment:Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
Synonyms:exact_synonym: cellular response to hypoxic stress;   cellular response to lowered oxygen tension


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cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAA2 acetyl-CoA acyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,028,636...79,057,720 JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747 		JBrowse link
G ADO 2-aminoethanethiol dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:14,698,582...14,702,635
Ensembl chr 4:14,698,616...14,699,428 		JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:19098126 RGD:8548506 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO oxygen-glucose deprivation RGD PMID:14526224 RGD:10047409 NCBI chr  X:101,275,027...101,307,551
Ensembl chr  X:101,275,017...101,307,367 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:20515660 RGD:5509097 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G ANGPT4 angiopoietin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:20,021,625...20,068,805
Ensembl chr24:20,022,322...20,064,023 		JBrowse link
G ANKRD1 ankyrin repeat domain 1 ISO RGD PMID:19299913 RGD:5133278 NCBI chr28:5,569,120...5,578,393
Ensembl chr28:5,569,501...5,601,956 		JBrowse link
G AQP1 aquaporin 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720 		JBrowse link
G AQP3 aquaporin 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24462679) MGI
Ensembl		 PMID:24462679 GO_REF:0000107 NCBI chr11:50,517,509...50,524,565 JBrowse link
G ASL argininosuccinate lyase ISO RGD PMID:11097477 RGD:1599264 NCBI chr 6:768,522...779,144
Ensembl chr 6:730,358...779,424 		JBrowse link
G ATF4 activating transcription factor 4 ISO oxygen-glucose deprivation RGD PMID:20444431 RGD:13464322 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:21346155 RGD:11341705 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G B3GAT1 beta-1,3-glucuronyltransferase 1 ISO RGD PMID:21400481 RGD:14390075 NCBI chr 5:741,231...747,641
Ensembl chr 5:745,747...748,899 		JBrowse link
G B9D2 B9 domain containing 2 involved_in ISO (PMID:31368162) BHF-UCL PMID:31368162 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G BBC3 BCL2 binding component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,742,793...108,750,832
Ensembl chr 1:108,741,713...108,749,946 		JBrowse link
G BCL2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 with serum deprivation
(PMID:7595537)		 RGD
MGI
Ensembl		 PMID:7595537 PMID:20669351 GO_REF:0000107 RGD:11353793 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BCL2L1 BCL2 like 1 ISO with serum deprivation RGD PMID:20669351 RGD:11353793 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:19565561 RGD:4891057 NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:19273585) RGD
Ensembl
MGI		 PMID:17379825 PMID:19273585 GO_REF:0000107 RGD:9685412 NCBI chr28:40,037,681...40,050,499
Ensembl chr28:40,038,643...40,049,797 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like acts_upstream_of_or_within ISO (PMID:19273585) MGI PMID:19273585 NCBI chr25:31,133,512...31,149,750
Ensembl chr25:31,136,168...31,148,905 		JBrowse link
G BRIP1 BRCA1 interacting helicase 1 ISO RGD PMID:12511571 RGD:11251702 NCBI chr 9:34,804,285...34,984,640
Ensembl chr 9:34,806,535...34,983,788 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO oxygen-glucose deprivation RGD PMID:23421680 RGD:13514095 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647 		JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:21073657 RGD:7206834 NCBI chr33:25,340,822...25,432,814
Ensembl chr33:25,405,846...25,432,559 		JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:29069575 RGD:151347449 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G CBL Cbl proto-oncogene ISO oxygen-glucose deprivation RGD PMID:24229686 RGD:11038824 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G CBS cystathionine beta-synthase involved_in ISO PMID:20149843 UniProt PMID:20149843 RGD:8554341 NCBI chr31:37,230,900...37,247,170 JBrowse link
G CCN1 cellular communication network factor 1 ISO RGD PMID:30371213 RGD:329845516 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994 		JBrowse link
G CCNA2 cyclin A2 ISO RGD PMID:25289051 RGD:10054493 NCBI chr19:18,317,866...18,324,592
Ensembl chr19:18,318,004...18,323,691 		JBrowse link
G CCNB1 cyclin B1 ISO RGD PMID:12374461 RGD:2316579 NCBI chr 2:54,256,957...54,264,749 JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:28854428 RGD:152025191 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:12031707 RGD:8663470 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995 		JBrowse link
G CLCA1 chloride channel accessory 1 ISO RGD PMID:18616988 RGD:4188872 NCBI chr 6:61,620,755...61,650,111
Ensembl chr 6:61,620,995...61,650,083 		JBrowse link
G COX4I2 cytochrome c oxidase subunit 4I2 ISO RGD PMID:23303788 RGD:11344908 NCBI chr24:21,122,033...21,128,368
Ensembl chr24:21,120,213...21,128,320 		JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO (PMID:18752464)
(MGI:5543770|PMID:18752464)		 UniProt PMID:18752464 MGI:5543770 NCBI chr 3:54,405,140...54,499,614
Ensembl chr 3:54,405,717...54,500,221 		JBrowse link
G CPEB2 cytoplasmic polyadenylation element binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:65,200,175...65,277,353
Ensembl chr 3:65,203,759...65,267,967 		JBrowse link
G CYBB cytochrome b-245 beta chain ISO RGD PMID:21302291 RGD:11040609 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO oxygen-glucose deprivation RGD PMID:17910051 RGD:5144007 NCBI chr  X:60,462,290...60,513,155
Ensembl chr  X:60,463,526...60,464,548 		JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO oxygen-glucose deprivation RGD PMID:17910051 RGD:5144007 NCBI chr22:2,914,960...2,962,517
Ensembl chr22:2,917,514...2,918,551 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:18664364 RGD:150429768 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275 		JBrowse link
G DICER1 dicer 1, ribonuclease III ISO oxygen-glucose deprivation RGD PMID:26294080 RGD:11553310 NCBI chr 8:63,970,245...64,029,438
Ensembl chr 8:63,972,027...64,019,879 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 ISO oxygen-glucose deprivation RGD PMID:30653356 RGD:155663383 NCBI chr30:8,059,463...8,068,742
Ensembl chr30:8,059,512...8,067,940 		JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 acts_upstream_of
involved_in		 ISO (PMID:19130895), (PMID:23474458), (PMID:26980435)
(PMID:30696468)		 UniProt PMID:19130895 PMID:23474458 PMID:26980435 PMID:30696468 NCBI chr 5:45,055,294...45,119,595
Ensembl chr 5:44,884,283...45,120,203 		JBrowse link
G DNM1L dynamin 1 like ISO oxygen-glucose deprivation RGD PMID:23658809 RGD:12738215 NCBI chr27:16,161,855...16,211,983
Ensembl chr27:16,163,357...16,211,957 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO RGD PMID:24282625 RGD:9589039 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:20969567 RGD:7248614 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287 		JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:9551744 RGD:8662285 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:8,053,486...8,110,791
Ensembl chr 4:8,053,837...8,109,325 		JBrowse link
G EGLN2 egl-9 family hypoxia inducible factor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:112,992,779...113,001,836
Ensembl chr 1:112,992,780...113,000,677 		JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:12,873,755...12,901,728
Ensembl chr 8:12,875,387...12,901,709 		JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:21220915 RGD:5131857 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 ISO RGD PMID:10100614 RGD:10401146 NCBI chr16:27,389,850...27,410,154
Ensembl chr16:27,390,181...27,410,110 		JBrowse link
G ELN elastin ISO RGD PMID:16055482 RGD:9585727 NCBI chr 6:6,299,524...6,331,425
Ensembl chr 6:6,300,727...6,331,325 		JBrowse link
G ENDOG endonuclease G ISO RGD PMID:17379825 RGD:9685412 NCBI chr 9:54,809,470...54,812,795
Ensembl chr 9:54,809,530...54,813,042 		JBrowse link
G ENO1 enolase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr 5:62,300,805...62,314,508
Ensembl chr 5:62,300,808...62,304,093 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12099714 GO_REF:0000107 GO_REF:0000118 RGD:11041576 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844 		JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha ISO RGD PMID:12752442 RGD:10401130 NCBI chr 8:28,864,642...28,913,864
Ensembl chr 8:28,864,925...28,914,368 		JBrowse link
G FABP1 fatty acid binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:38,242,119...38,247,969
Ensembl chr17:38,242,119...38,247,962 		JBrowse link
G FAM162A family with sequence similarity 162 member A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr33:25,525,408...25,552,272
Ensembl chr33:25,525,411...25,552,256 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:12031707 RGD:8663470 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO RGD PMID:31093967 RGD:155882597 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:11981751 RGD:634296 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621 		JBrowse link
G FMN2 formin 2 involved_in ISO (PMID:23375502) UniProt PMID:23375502 NCBI chr 7:31,657,371...32,024,777
Ensembl chr 7:31,697,245...32,023,472 		JBrowse link
G FNDC1 fibronectin type III domain containing 1 acts_upstream_of_or_within ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 1:48,501,657...48,602,962
Ensembl chr 1:48,501,355...48,602,336 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467 		JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:24278276 RGD:10402204 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198 		JBrowse link
G FXN frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chr 1:88,288,566...88,311,228
Ensembl chr 1:88,288,566...88,311,228 		JBrowse link
G GAD1 glutamate decarboxylase 1 ISO RGD PMID:11259512 RGD:401900595 NCBI chr36:15,351,289...15,391,701
Ensembl chr36:15,349,683...15,391,824 		JBrowse link
G GAD2 glutamate decarboxylase 2 ISO RGD PMID:11259512 RGD:401900595 NCBI chr 2:7,365,708...7,450,893
Ensembl chr 2:7,365,283...7,450,893 		JBrowse link
G GATA6 GATA binding protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G GNB1 G protein subunit beta 1 acts_upstream_of_or_within ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295 		JBrowse link
G GNGT1 G protein subunit gamma transducin 1 acts_upstream_of_or_within ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr14:19,081,676...19,420,261
Ensembl chr14:19,415,510...19,420,255 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24011070) RGD
MGI
TreeGrafter
Ensembl		 PMID:18248612 PMID:19220706 PMID:24011070 GO_REF:0000107 GO_REF:0000118 RGD:9068456 RGD:9068884 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G HIF3A hypoxia inducible factor 3 subunit alpha NOT|involved_in ISO
IEA		 (PMID:11573933) UniProt
TreeGrafter		 PMID:11573933 GO_REF:0000118 NCBI chr 1:109,479,456...109,504,271
Ensembl chr 1:109,479,128...109,504,274 		JBrowse link
G HIGD1A HIG1 hypoxia inducible domain family member 1A acts_upstream_of_or_within ISO (PMID:25683712)
(PMID:16815968), (PMID:21856340)		 MGI PMID:16815968 PMID:21856340 PMID:25683712 NCBI chr23:11,893,117...11,903,934 JBrowse link
G HILPDA hypoxia inducible lipid droplet associated involved_in ISO (PMID:10690527) UniProt PMID:10690527 NCBI chr14:7,957,811...7,959,878 JBrowse link
G HMOX1 heme oxygenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:24177414 RGD:10445837 NCBI chr24:31,847,864...31,908,337
Ensembl chr24:31,847,961...31,905,916 		JBrowse link
G HP1BP3 heterochromatin protein 1 binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,164,239...78,203,032
Ensembl chr 2:78,164,173...78,201,555 		JBrowse link
G HYOU1 hypoxia up-regulated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,795,750...14,808,203
Ensembl chr 5:14,795,750...14,807,262 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:20631551 RGD:8662392 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914 		JBrowse link
G IL7 interleukin 7 ISO RGD PMID:19055876 RGD:10402937 NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737 		JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:30765322 RGD:329849112 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO RGD PMID:15793310 RGD:1579809 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO oxygen-glucose deprivation RGD PMID:16135072 PMID:22159112 RGD:12904046 RGD:6893269 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:17285299 RGD:6482794 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 ISO RGD PMID:17285299 RGD:6482794 NCBI chr27:20,806,670...21,278,638
Ensembl chr27:20,805,842...21,350,083 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr20:49,358,904...49,360,746
Ensembl chr20:49,359,399...49,360,442 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr20:44,737,021...44,738,932
Ensembl chr20:44,736,832...44,763,020 		JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:24705172 RGD:9831164 NCBI chr 7:12,893,654...13,092,319
Ensembl chr 7:12,894,149...13,090,110 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 ISO RGD PMID:12215606 RGD:2316539 NCBI chr17:20,732,779...20,771,104
Ensembl chr17:20,732,819...20,768,730 		JBrowse link
G KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO RGD PMID:19461047 RGD:10412041 NCBI chr 4:41,536,841...41,545,523
Ensembl chr 4:41,537,225...41,545,344 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:26439051 RGD:401794572 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701 		JBrowse link
G KDM6A lysine demethylase 6A ISO RGD PMID:30887465 RGD:151665136 NCBI chr  X:38,745,854...38,964,029
Ensembl chr  X:38,745,854...38,959,842 		JBrowse link
G LCN2 lipocalin 2 ISO oxygen-glucose deprivation RGD PMID:24916903 RGD:126790489 NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038 		JBrowse link
G LMNA lamin A/C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,702,491...41,719,870
Ensembl chr 7:41,508,450...41,746,931 		JBrowse link
G LOC100688796 ATP synthase F(0) complex subunit B1, mitochondrial ISO RGD PMID:29300489 RGD:13792656 NCBI chr17:63,940,486...63,954,982
Ensembl chr 6:40,613,415...40,625,979
Ensembl chr 6:40,613,415...40,625,979 		JBrowse link
G LOC607881 potassium voltage-gated channel subfamily D member 2-like involved_in ISO PMID:25352783 UniProt PMID:25352783 RGD:10047379
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO oxygen-glucose deprivation RGD PMID:32734729 RGD:155804275 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G MDM4 MDM4 regulator of p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:1,055,978...1,122,348
Ensembl chr38:1,056,109...1,107,166 		JBrowse link
G MFN1 mitofusin 1 ISO oxygen-glucose deprivation RGD PMID:23658809 PMID:27833818 RGD:12738215 RGD:12910766 NCBI chr34:12,785,799...12,816,881
Ensembl chr34:12,785,856...12,815,994 		JBrowse link
G MFN2 mitofusin 2 ISO oxygen-glucose deprivation RGD PMID:23658809 PMID:28478070 RGD:12738215 RGD:12910733 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
G MGARP mitochondria localized glutamic acid rich protein involved_in ISO (MGI:3850758|PMID:19528298) UniProt PMID:19528298 MGI:3850758 NCBI chr19:3,411,718...3,423,589
Ensembl chr19:3,411,778...3,423,330 		JBrowse link
G MIEF1 mitochondrial elongation factor 1 ISO RGD PMID:25911325 RGD:12880381 NCBI chr10:25,534,231...25,548,565
Ensembl chr10:25,536,288...25,546,369 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:19462902 RGD:4890975
G MIR107 microRNA mir-107 ISO oxygen-glucose deprivation RGD PMID:26294080 RGD:11553310 NCBI chr28:4,484,653...4,484,710
Ensembl chr28:4,484,646...4,484,718 		JBrowse link
G MIR126 microRNA mir-126 involved_in ISO (PMID:28578351) BHF-UCL PMID:28578351 NCBI chr 9:48,879,438...48,879,496
Ensembl chr 9:48,879,432...48,879,504 		JBrowse link
G MIR140 microRNA mir-140 involved_in ISO (PMID:27021683) BHF-UCL
RGD		 PMID:27021683 PMID:28922712 RGD:329347824 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR143 microRNA mir-143 ISO RGD PMID:28887629 RGD:155882580 NCBI chr 4:59,534,535...59,534,589
Ensembl chr 4:59,534,535...59,534,594 		JBrowse link
G MIR17 microRNA mir-17 involved_in ISO (PMID:27640178) BHF-UCL PMID:27640178 NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083 		JBrowse link
G MIR199-2 microRNA mir-199-2 acts_upstream_of_or_within ISO (PMID:24011070) MGI PMID:24011070 NCBI chr 7:26,812,766...26,812,824
Ensembl chr 7:26,812,735...26,812,838 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:31368162) BHF-UCL PMID:31368162 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MIR214 microRNA mir-214 involved_in
acts_upstream_of_or_within		 ISO (PMID:27144530)
(PMID:24011070)		 BHF-UCL
MGI		 PMID:24011070 PMID:27144530 NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670 		JBrowse link
G MIR222 microRNA mir-222 ISO RGD PMID:28854428 RGD:152025191 NCBI chr  X:39,524,519...39,524,608
Ensembl chr  X:39,524,519...39,524,608 		JBrowse link
G MIR223 microRNA mir-223 ISO RGD PMID:29608885 RGD:21408565 NCBI chr  X:50,838,131...50,838,233
Ensembl chr  X:50,838,131...50,838,233 		JBrowse link
G MIR34A microRNA mir-34a involved_in ISO (PMID:27302634) BHF-UCL PMID:27302634 NCBI chr 5:62,485,832...62,485,897
Ensembl chr 5:62,485,832...62,485,897 		JBrowse link
G MIR448 microRNA mir-448 involved_in ISO (PMID:33108349) BHF-UCL PMID:33108349 NCBI chr  X:87,558,063...87,558,172
Ensembl chr  X:87,558,063...87,558,172 		JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor ISO RGD PMID:15642952 RGD:10449018 NCBI chr15:16,815,102...16,825,321
Ensembl chr15:16,815,294...16,825,350 		JBrowse link
G MST1 macrophage stimulating 1 ISO RGD PMID:23647599 RGD:10448278 NCBI chr20:39,582,237...39,586,958
Ensembl chr20:39,582,282...39,586,908 		JBrowse link
G MSTN myostatin ISO RGD PMID:30765322 RGD:329849112 NCBI chr37:729,172...734,255
Ensembl chr37:729,172...734,362 		JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT3 metallothionein 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 2:59,624,849...59,626,424 JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G MYOCD myocardin ISO RGD PMID:20621093 RGD:5132874 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase ISO oxygen-glucose deprivation RGD PMID:28528966 RGD:13781879 NCBI chr18:14,110,045...14,211,268
Ensembl chr18:13,993,022...14,208,657 		JBrowse link
G NDNF neuron derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:19,009,966...19,053,047
Ensembl chr19:19,036,372...19,049,937 		JBrowse link
G NDP norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:30988181) MGI PMID:30988181 NCBI chr  X:37,949,560...37,975,573
Ensembl chr  X:37,950,489...37,975,346 		JBrowse link
G NDRG1 N-myc downstream regulated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,689,294...29,745,964
Ensembl chr13:29,650,444...29,746,382 		JBrowse link
G NECAB3 N-terminal EF-hand calcium binding protein 3 ISO RGD PMID:19088195 RGD:2316261 NCBI chr24:22,895,149...22,904,689
Ensembl chr24:22,878,402...22,904,656 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23904790 GO_REF:0000107 RGD:10412703 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G NGB neuroglobin involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:50,081,960...50,086,071
Ensembl chr 8:50,081,960...50,085,435 		JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:33,815,343...33,817,465
Ensembl chr25:33,815,095...33,817,474 		JBrowse link
G NOG noggin ISO RGD PMID:25740156 RGD:12801489 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G NONO non-POU domain containing octamer binding ISO oxygen-glucose deprivation RGD PMID:32424772 RGD:155882459 NCBI chr  X:55,618,032...55,632,237
Ensembl chr  X:55,618,095...55,631,388 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,307,039...108,315,732
Ensembl chr 1:108,307,042...108,316,495 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G NPEPPS aminopeptidase puromycin sensitive involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:23,866,977...23,971,930
Ensembl chr 9:23,866,990...23,972,231 		JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:21444791 RGD:11535018 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO RGD PMID:27833818 RGD:12910766 NCBI chr23:52,068,123...52,154,410
Ensembl chr23:52,068,118...52,151,593 		JBrowse link
G OPRD1 opioid receptor delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:71,685,129...71,721,692
Ensembl chr 2:71,689,084...71,721,875 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:427,827...436,880
Ensembl chr 9:427,830...436,064 		JBrowse link
G PALLD palladin, cytoskeletal associated protein ISO RGD PMID:16481593 RGD:2325785 NCBI chr25:19,147,310...19,568,712
Ensembl chr25:19,146,898...19,553,679 		JBrowse link
G PARK7 Parkinsonism associated deglycase ISO RGD PMID:29069575 RGD:151347449 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO RGD PMID:24177414 RGD:10445837 NCBI chr24:42,538,858...42,544,200
Ensembl chr24:42,538,882...42,544,198 		JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:23647599 RGD:10448278 NCBI chr 1:40,494,441...40,539,453
Ensembl chr 1:40,494,461...40,538,937 		JBrowse link
G PGK1 phosphoglycerate kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,374,743...60,396,244
Ensembl chr  X:60,374,754...60,423,947 		JBrowse link
G PHB2 prohibitin 2 ISO RGD PMID:25031298 RGD:12903263 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G PLAU plasminogen activator, urokinase ISO RGD PMID:19490965 RGD:7241802 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14699081), (PMID:20810912) UniProt PMID:14699081 PMID:20810912 NCBI chr 1:16,469,793...16,472,910
Ensembl chr 1:16,469,793...16,472,910 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:4,492,867...4,579,340
Ensembl chr12:4,492,672...4,579,340 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO PMID:29695452 BHF-UCL PMID:29695452 RGD:150521636 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22527940 RGD:7242177 NCBI chr 3:85,645,942...86,284,570
Ensembl chr 3:86,016,140...86,281,269 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO oxygen-glucose deprivation RGD PMID:21525936 RGD:10054236 NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:17720864 RGD:2316813 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18070622) Ensembl
MGI		 PMID:18070622 GO_REF:0000107 NCBI chr10:47,976,929...48,464,614
Ensembl chr10:47,976,768...48,535,296 		JBrowse link
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824 		JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:24875179) MGI PMID:24875179 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G PTGIS prostaglandin I2 synthase involved_in IEA
ISO		 Ensembl
RGD		 PMID:19344900 GO_REF:0000107 RGD:401960096 NCBI chr24:36,129,091...36,162,525
Ensembl chr24:36,132,173...36,162,509 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G PTN pleiotrophin ISO RGD PMID:16226713 PMID:17925408 RGD:10044023 RGD:9834996 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO RGD PMID:18278556 RGD:401965430 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D ISO RGD PMID:35848503 RGD:401976433 NCBI chr11:29,100,913...31,278,495
Ensembl chr11:29,104,448...29,501,600 		JBrowse link
G RGCC regulator of cell cycle involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:9,199,204...9,209,297 JBrowse link
G RNF146 ring finger protein 146 ISO RGD PMID:26218637 RGD:13524866 NCBI chr 1:65,988,600...66,010,873
Ensembl chr 1:65,988,656...66,010,881 		JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO oxygen-glucose deprivation RGD PMID:23994690 RGD:243048442 NCBI chr31:8,082,363...8,594,623
Ensembl chr31:7,626,126...8,593,728 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:25,315,974...26,026,708
Ensembl chr30:25,325,275...26,026,623 		JBrowse link
G RTN4 reticulon 4 involved_in ISO (MGI:6274961|PMID:27763637) UniProt PMID:27763637 MGI:6274961 NCBI chr10:55,884,452...55,954,476
Ensembl chr10:55,885,125...55,936,574 		JBrowse link
G S100B S100 calcium binding protein B ISO RGD PMID:19910580 RGD:2325647 NCBI chr31:39,783,990...39,788,289
Ensembl chr31:39,784,506...39,788,183 		JBrowse link
G SCN2A sodium voltage-gated channel alpha subunit 2 involved_in ISO PMID:28029095 UniProt PMID:28029095 RGD:14390052 NCBI chr36:10,472,496...10,605,055
Ensembl chr36:10,472,361...10,602,685 		JBrowse link
G SDHD succinate dehydrogenase complex subunit D involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15572694) Ensembl
MGI		 PMID:15572694 GO_REF:0000107 NCBI chr 5:21,030,295...21,041,125 JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:10590062 RGD:8547811 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:20620956) UniProt PMID:20620956 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583 		JBrowse link
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr26:16,228,831...16,244,104
Ensembl chr26:16,234,710...16,240,012 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:21325818 RGD:5688411 NCBI chr27:3,788,785...3,823,852
Ensembl chr27:3,787,855...3,822,672 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 ISO RGD PMID:10646513 RGD:1598899 NCBI chr12:12,632,233...12,644,669
Ensembl chr12:12,634,194...12,644,667 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO RGD PMID:20868366 RGD:7349316 NCBI chr 5:32,238,095...32,244,022
Ensembl chr 5:32,238,095...32,244,021 		JBrowse link
G SLC35E3 solute carrier family 35 member E3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,892,999...10,908,142 JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO RGD PMID:17394575 RGD:1642726 NCBI chr17:32,004,207...32,381,399
Ensembl chr17:32,005,245...32,307,700 		JBrowse link
G SLC8A3 solute carrier family 8 member A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:43,780,363...43,926,142
Ensembl chr 8:43,781,120...43,926,343 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO RGD PMID:20868366 RGD:7349316 NCBI chr 2:73,054,742...73,103,364
Ensembl chr 2:73,054,742...73,103,364 		JBrowse link
G SLIT2 slit guidance ligand 2 ISO oxygen-glucose deprivation RGD PMID:26764532 RGD:11573340 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:20380727 RGD:2324980 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G STC1 stanniocalcin 1 ISO RGD PMID:15485913 RGD:2324700 NCBI chr25:33,615,436...33,628,138
Ensembl chr25:33,615,451...33,625,218 		JBrowse link
G STC2 stanniocalcin 2 ISO RGD PMID:15485913 RGD:2324700 NCBI chr 4:39,151,951...39,165,514
Ensembl chr 4:39,152,503...39,162,343 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 ISO RGD PMID:17289031 RGD:9587773 NCBI chr37:11,199,937...11,229,743
Ensembl chr37:11,200,590...11,229,754 		JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:21402781) MGI PMID:21402781 NCBI chr  X:41,894,623...41,907,854
Ensembl chr  X:41,893,045...41,906,403 		JBrowse link
G SUV39H2 SUV39H2 histone lysine methyltransferase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21402781) MGI
Ensembl		 PMID:21402781 GO_REF:0000107 NCBI chr 2:21,715,677...21,749,732
Ensembl chr 2:21,728,964...21,749,597 		JBrowse link
G TBL2 transducin beta like 2 involved_in ISO (PMID:25393282) ParkinsonsUK-UCL PMID:25393282 NCBI chr 6:6,656,158...6,664,900
Ensembl chr 6:6,656,035...6,660,963 		JBrowse link
G TERT telomerase reverse transcriptase involved_in ISO
IEA		 RGD
Ensembl		 PMID:24376652 GO_REF:0000107 RGD:11038675 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:28854428 RGD:152025191 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288 		JBrowse link
G TP53 tumor protein p53 involved_in IEA
ISO		 Ensembl
RGD		 PMID:17289031 GO_REF:0000107 RGD:9587773 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 ISO RGD PMID:19889962 RGD:7247600 NCBI chr23:38,350,066...38,416,086
Ensembl chr23:38,350,278...38,414,464 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 ISO RGD PMID:19889962 RGD:7247600 NCBI chr 5:29,897,378...30,007,885
Ensembl chr 5:29,897,210...30,007,723 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,767,345...75,812,278
Ensembl chr 1:75,767,188...75,838,051 		JBrowse link
G UCN2 urocortin 2 ISO RGD PMID:14519439 RGD:2306174 NCBI chr20:40,551,060...40,552,920 JBrowse link
G UCN3 urocortin 3 ISO RGD PMID:14519439 RGD:2306174 NCBI chr 2:30,541,316...30,547,839
Ensembl chr 2:30,541,779...30,542,282 		JBrowse link
G VASN vasorin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21658601) Ensembl
MGI		 PMID:21658601 GO_REF:0000107 NCBI chr 6:37,014,704...37,025,734
Ensembl chr 6:37,015,333...37,017,351 		JBrowse link
G VEGFA vascular endothelial growth factor A acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (PMID:10575000) MGI
Ensembl
UniProt		 PMID:10575000 GO_REF:0000024 GO_REF:0000107 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
G VLDLR very low density lipoprotein receptor ISO RGD PMID:19233325 RGD:2324641 NCBI chr 1:91,242,010...91,277,030
Ensembl chr 1:91,241,509...91,272,495 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514 		JBrowse link
hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBB cytochrome b-245 beta chain ISO RGD PMID:21302291 RGD:11040609 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8470821) Ensembl
MGI		 PMID:8470821 GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:16,918,329...16,944,532
Ensembl chr36:16,918,058...16,944,620 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:19,994,383...20,058,979
Ensembl chr  X:19,994,393...20,058,485 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor acts_upstream_of ISO (PMID:25186293) MGI PMID:25186293 NCBI chr20:8,206,616...8,211,347
Ensembl chr20:8,206,616...8,211,323 		JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:40,037,681...40,050,499
Ensembl chr28:40,038,643...40,049,797 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20935145) Ensembl
MGI		 PMID:20935145 GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
negative regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAXX death domain associated protein ISO cell death RGD PMID:17289031 RGD:9587773 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,548,852...62,683,687
Ensembl chr 6:62,549,152...62,683,729 		JBrowse link
G DRD1 dopamine receptor D1 ISO cell death RGD PMID:27638511 RGD:13506952 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287 		JBrowse link
G DRD2 dopamine receptor D2 ISO cell death RGD PMID:27638511 RGD:13506952 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241 		JBrowse link
G EPHA4 EPH receptor A4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:31150684) ARUK-UCL
Ensembl		 PMID:31150684 GO_REF:0000107 NCBI chr37:27,670,143...27,809,642
Ensembl chr37:27,677,566...27,809,646 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO cell death RGD PMID:24048861 RGD:10412727 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO cell death RGD PMID:18539296 RGD:9590185 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502 		JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENO1 enolase 1 involved_in ISO (PMID:15459207) CAFA PMID:15459207 NCBI chr 5:62,300,805...62,314,508
Ensembl chr 5:62,300,808...62,304,093 		JBrowse link
G HYOU1 hypoxia up-regulated 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:14,795,750...14,808,203
Ensembl chr 5:14,795,750...14,807,262 		JBrowse link
G KDM6A lysine demethylase 6A ISO RGD PMID:30887465 RGD:151665136 NCBI chr  X:38,745,854...38,964,029
Ensembl chr  X:38,745,854...38,959,842 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta involved_in ISO (MGI:6444553|PMID:30496354) BHF-UCL PMID:30496354 MGI:6444553 NCBI chr23:34,832,661...34,955,410
Ensembl chr23:34,836,540...34,993,939 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) ParkinsonsUK-UCL PMID:21075086 NCBI chr27:4,921,606...4,944,830
Ensembl chr27:4,921,606...4,944,783 		JBrowse link
negative regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COMMD1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO (PMID:17371845) MGI PMID:17371845 NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO (PMID:25186293) MGI PMID:25186293 NCBI chr20:8,206,616...8,211,347
Ensembl chr20:8,206,616...8,211,323 		JBrowse link
positive regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha ISO oxygen-glucose deprivation-induced cell death RGD PMID:23516428 RGD:9589049 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:24705172 RGD:9831164 NCBI chr 7:12,893,654...13,092,319
Ensembl chr 7:12,894,149...13,090,110 		JBrowse link
G MIR145 microRNA mir-145 acts_upstream_of_or_within ISO (PMID:31150684) ARUK-UCL PMID:31150684 NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210 		JBrowse link
G ZC3H7B zinc finger CCCH-type containing 7B ISO reduced metabolism in hypoxia-treated PC12 cells
reduced metabolism in hypoxia mimic CoCl2-treated PC12 cells		 RGD PMID:18586071 PMID:19103185 RGD:2311713 RGD:2311718 NCBI chr10:23,882,379...23,944,850
Ensembl chr10:23,884,981...23,920,131 		JBrowse link
positive regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RWDD3 RWD domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22009797) InterPro
MGI
TreeGrafter
Ensembl		 PMID:22009797 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:54,082,061...54,094,218
Ensembl chr 6:54,079,751...54,086,489 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK3 polo like kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:15,519,042...15,523,960
Ensembl chr15:15,519,026...15,524,230 		JBrowse link
regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AJUBA ajuba LIM protein involved_in ISO (PMID:22286099) UniProt PMID:22286099 NCBI chr 8:3,272,408...3,302,179
Ensembl chr 8:3,272,405...3,301,708 		JBrowse link
G CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:581,276...585,367
Ensembl chr 6:581,280...585,301 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:18054269 RGD:9068899 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) ARUK-UCL PMID:29353861 MGI:6271078 NCBI chr17:7,931,786...8,012,484
Ensembl chr17:7,934,739...8,178,707 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:19450559 RGD:7242910 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,062,802...40,074,221
Ensembl chr20:40,064,599...40,074,082 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in ISO (PMID:10205047) DisProt PMID:10205047 NCBI chr20:8,206,616...8,211,347
Ensembl chr20:8,206,616...8,211,323 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    response to stimulus 9451
      response to stress 4059
        response to hypoxia 497
          cellular response to hypoxia 233
            hypoxia-inducible factor-1alpha signaling pathway + 7
            intrinsic apoptotic signaling pathway in response to hypoxia + 10
            negative regulation of cellular response to hypoxia + 16
            positive regulation of cellular response to hypoxia 4
            positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia 1
            regulation of cellular response to hypoxia + 26
Path 2
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      cellular response to stimulus 8033
        cellular response to chemical stimulus 3222
          cellular response to oxygen levels 275
            cellular response to decreased oxygen levels 255
              cellular response to hypoxia 233
                hypoxia-inducible factor-1alpha signaling pathway + 7
                intrinsic apoptotic signaling pathway in response to hypoxia + 10
                negative regulation of cellular response to hypoxia + 16
                positive regulation of cellular response to hypoxia 4
                positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia 1
                regulation of cellular response to hypoxia + 26
paths to the root