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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to hypoxia
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Accession:GO:0071456 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
Comment:Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
Synonyms:exact_synonym: cellular response to hypoxic stress;   cellular response to lowered oxygen tension

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cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07004992.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:173,275,336...173,284,941 JBrowse link
G AABR07060833.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 4:96,562,725...96,564,611 JBrowse link
G AC130253.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:37,582,706...37,583,167 JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18371312)		 Ensembl
RGD		 PMID:18371312 GO_REF:0000107 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (PMID:18566576) RGD PMID:18566576 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349 		JBrowse link
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:19098126 RGD:8548506 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Ak4 adenylate kinase 4 involved_in
acts_upstream_of		 ISO
ISS		 (PMID:30696468)
GO_REF:0000024
(PMID:19130895), (PMID:23474458), (PMID:26980435)		 RGD
UniProt		 PMID:19130895 PMID:23474458 PMID:26980435 PMID:30696468 GO_REF:0000024 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA RGD PMID:20515660 RGD:5509097 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Angpt4 angiopoietin 4 involved_in ISO (PMID:12958144) RGD PMID:12958144 NCBI chr 3:147,421,724...147,455,670
Ensembl chr 3:147,422,095...147,455,670 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 IEP RGD PMID:19299913 RGD:5133278 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548 		JBrowse link
G Aqp1 aquaporin 1 involved_in ISO
ISS		 (PMID:18275976)
GO_REF:0000024		 RGD
UniProt		 PMID:18275976 GO_REF:0000024 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) involved_in ISO
IEA		 (PMID:24462679)
GO_REF:0000107		 RGD
Ensembl		 PMID:24462679 GO_REF:0000107 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245 		JBrowse link
G Asl argininosuccinate lyase IEP RGD PMID:11097477 RGD:1599264 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b IEP RGD PMID:29300489 RGD:13792656 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
Ensembl chr 2:208,566,385...208,577,146 		JBrowse link
G Atp7a ATPase copper transporting alpha IEP RGD PMID:21346155 RGD:11341705 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644 		JBrowse link
G B3gat1 beta-1,3-glucuronyltransferase 1 IEP RGD PMID:21400481 RGD:14390075 NCBI chr 8:27,777,024...27,804,368
Ensembl chr 8:27,777,179...27,804,515 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO
IBA		 (PMID:20810912)
PMID:21873635		 RGD PMID:20810912, PMID:21873635 RGD:13792537 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO (PMID:20810912) RGD PMID:20810912 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in		 IEP
ISO
IEA		 with serum deprivation
(MGI:77298|PMID:7595537)
GO_REF:0000107		 RGD
Ensembl		 PMID:7595537, PMID:20669351 GO_REF:0000107 MGI:77298, RGD:11353793 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 IEP with serum deprivation RGD PMID:20669351 RGD:11353793 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP RGD PMID:19565561 RGD:4891057 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in IEP
ISO		 UniProtKB:O60238 (PMID:19273585), (PMID:20436456) RGD PMID:19273585 PMID:20436456, PMID:17379825 RGD:9685412 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in ISO UniProtKB:Q12983 (PMID:19273585) RGD PMID:19273585 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029 		JBrowse link
G Brip1 BRCA1 interacting helicase 1 IEP RGD PMID:12511571 RGD:11251702 NCBI chr10:73,507,009...73,632,742
Ensembl chr10:73,507,100...73,629,581 		JBrowse link
G Casr calcium-sensing receptor IEP RGD PMID:21073657 RGD:7206834 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771 		JBrowse link
G Cbs cystathionine beta synthase involved_in IDA PMID:20149843 UniProt PMID:20149843 RGD:8554341 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751 		JBrowse link
G Ccna2 cyclin A2 IEP RGD PMID:25289051 RGD:10054493 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214 		JBrowse link
G Ccnb1 cyclin B1 IEP RGD PMID:12374461 RGD:2316579 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IEP RGD PMID:12031707 RGD:8663470 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251 		JBrowse link
G Clca1 chloride channel accessory 1 IEP RGD PMID:18616988 RGD:4188872 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744 		JBrowse link
G Cox4i2 cytochrome c oxidase subunit 4i2 IEP RGD PMID:23303788 RGD:11344908 NCBI chr 3:148,234,546...148,245,424
Ensembl chr 3:148,234,193...148,245,416 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO
ISS		 (PMID:18752464)
(MGI:5543770|PMID:18752464)
GO_REF:0000024		 RGD
UniProt		 PMID:18752464 GO_REF:0000024 MGI:5543770 NCBI chr 1:143,171,457...143,278,485
Ensembl chr 1:143,171,264...143,278,485 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5543770|PMID:18752464)
(PMID:18752464)		 UniProt
RGD		 PMID:18752464 GO_REF:0000024 MGI:5543770 NCBI chr14:72,327,929...72,382,519
Ensembl chr14:72,331,705...72,380,330 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (MGI:4821502|PMID:20675597) RGD PMID:20675597 MGI:4821502 NCBI chr13:113,824,886...113,872,097
Ensembl chr13:113,824,892...113,872,097 		JBrowse link
G Cybb cytochrome b-245 beta chain IEP RGD PMID:21302291 RGD:11040609 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha IEP RGD PMID:24282625 RGD:9589039 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577 		JBrowse link
G Drd1 dopamine receptor D1 IEP RGD PMID:20969567 RGD:7248614 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541 		JBrowse link
G E2f1 E2F transcription factor 1 IEP RGD PMID:19088195 RGD:2316261 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721 		JBrowse link
G Edn1 endothelin 1 IEP RGD PMID:9551744 RGD:8662285 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113 		JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,969,456...83,977,665
Ensembl chr 1:83,969,457...83,977,236 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795 		JBrowse link
G Egr1 early growth response 1 IEP RGD PMID:21220915 RGD:5131857 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 IDA RGD PMID:10100614 RGD:10401146 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248 		JBrowse link
G Eln elastin IEP RGD PMID:16055482 RGD:9585727 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Endog endonuclease G IEP RGD PMID:17379825 RGD:9685412 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592 		JBrowse link
G Eno1 enolase 1 involved_in IDA PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609 		JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in IEP
IBA
ISO
IEA
ISS		 PMID:21873635
(PMID:11573933)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11573933, PMID:12099714, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:11041576, RGD:13792537 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha IEP RGD PMID:12752442 RGD:10401130 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381 		JBrowse link
G Fabp1 fatty acid binding protein 1 involved_in ISO (PMID:16175609) RGD PMID:16175609 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Fam162a family with sequence similarity 162, member A involved_in ISO
IBA		 (PMID:15082785)
(MGI:5319611|PMID:17316997)
PMID:21873635		 RGD PMID:15082785 PMID:17316997, PMID:21873635 MGI:5319611, RGD:13792537 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253 		JBrowse link
G Fas Fas cell surface death receptor IEP RGD PMID:12031707 RGD:8663470 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP RGD PMID:11981751 RGD:634296 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905 		JBrowse link
G Fmn2 formin 2 involved_in ISO (PMID:23375502) RGD PMID:23375502 NCBI chr13:92,569,256...92,887,302 JBrowse link
G Fndc1 fibronectin type III domain containing 1 involved_in IMP PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 1:47,605,211...47,687,499
Ensembl chr 1:47,605,262...47,687,504 		JBrowse link
G Foxo3 forkhead box O3 IEP RGD PMID:24278276 RGD:10402204 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144 		JBrowse link
G Gata6 GATA binding protein 6 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21127043)		 Ensembl
RGD		 PMID:21127043 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338 		JBrowse link
G Gnb1 G protein subunit beta 1 involved_in IDA PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986 		JBrowse link
G Gngt1 G protein subunit gamma transducin 1 involved_in IDA PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 4:28,972,339...28,975,419
Ensembl chr 4:28,972,434...28,975,419 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within
involved_in		 IEP
ISO
ISS
IBA
IMP		 MGI:101884|MGI:2676890|MGI:3618742 (MGI:5528778|PMID:24011070)
GO_REF:0000024
(PMID:11573933), (PMID:19528298), (PMID:19782034), (PMID:20810912), (PMID:20889502)
PMID:21873635		 RGD
UniProt		 PMID:11573933 PMID:19528298 PMID:19782034 PMID:20810912 PMID:20889502 PMID:24011070, PMID:19220706, PMID:21873635, PMID:18248612 GO_REF:0000024 MGI:5528778, RGD:9068456, RGD:13792537, RGD:9068884 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha NOT|involved_in ISO
IBA		 (PMID:11573933)
PMID:21873635		 RGD PMID:11573933, PMID:21873635 RGD:13792537 NCBI chr 1:78,976,318...78,997,869
Ensembl chr 1:78,976,318...78,997,869 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO (MGI:3654896|PMID:16815968), (MGI:5306879|PMID:21856340), (MGI:5643884|PMID:25683712) RGD PMID:16815968 PMID:21856340 PMID:25683712 MGI:3654896 MGI:5306879 MGI:5643884 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated involved_in ISO (PMID:10690527) RGD PMID:10690527 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:12511571) RGD PMID:12511571 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IEP RGD PMID:24177414 RGD:10445837 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003 		JBrowse link
G Hp1bp3 heterochromatin protein 1, binding protein 3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:25100860)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:25100860 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:156,581,732...156,609,059
Ensembl chr 5:156,581,732...156,609,059 		JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in ISO
IBA		 (PMID:10837345), (PMID:9020069)
PMID:21873635		 RGD PMID:9020069 PMID:10837345, PMID:21873635 RGD:13792537 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:20631551 RGD:8662392 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il7 interleukin 7 IEP RGD PMID:19055876 RGD:10402937 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IEP RGD PMID:15793310 RGD:1579809 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977 		JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP RGD PMID:22159112 RGD:6893269 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEP RGD PMID:17285299 RGD:6482794 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 IEP RGD PMID:17285299 RGD:6482794 NCBI chr 4:180,423,452...180,800,088
Ensembl chr 4:180,538,389...180,722,358 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 involved_in IDA PMID:25352783 UniProt PMID:25352783 RGD:10047379 NCBI chr 4:48,309,283...48,816,804 JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP RGD PMID:24705172 RGD:9831164 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:12215606 RGD:2316539 NCBI chr 6:27,154,274...27,190,209
Ensembl chr 6:27,151,612...27,190,132 		JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 IEP RGD PMID:19461047 RGD:10412041 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639 		JBrowse link
G Lmna lamin A/C involved_in ISO (PMID:20810912) RGD PMID:20810912 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:20810912) RGD PMID:20810912 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (PMID:20810912) RGD PMID:20810912 NCBI chr13:49,786,776...49,828,780
Ensembl chr13:49,792,794...49,828,720 		JBrowse link
G Mfn1 mitofusin 1 IEP RGD PMID:27833818 RGD:12910766 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698 		JBrowse link
G Mfn2 mitofusin 2 IEP RGD PMID:28478070 RGD:12910733 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145 		JBrowse link
G Mgarp mitochondria-localized glutamic acid-rich protein involved_in ISO (MGI:3850758|PMID:19528298) RGD PMID:19528298 MGI:3850758 NCBI chr 2:140,444,963...140,453,719
Ensembl chr 2:140,444,965...140,453,107 		JBrowse link
G Mief1 mitochondrial elongation factor 1 IEP RGD PMID:25911325 RGD:12880381 NCBI chr 7:121,462,962...121,478,545
Ensembl chr 7:121,462,966...121,478,546 		JBrowse link
G Mif macrophage migration inhibitory factor IEP RGD PMID:19462902 RGD:4890975 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Mir199a2 microRNA 199a-2 acts_upstream_of_or_within ISO MGI:101884|MGI:106918|MGI:2676890 (MGI:5528778|PMID:24011070) RGD PMID:24011070 MGI:5528778 NCBI chr13:80,125,487...80,125,596
Ensembl chr13:80,125,487...80,125,596 		JBrowse link
G Mir223 microRNA 223 IEP RGD PMID:29608885 RGD:21408565 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor IEP RGD PMID:15642952 RGD:10449018 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298 		JBrowse link
G Mst1 macrophage stimulating 1 IEP RGD PMID:23647599 RGD:10448278 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423 		JBrowse link
G Mt3 metallothionein 3 involved_in ISO (PMID:18206644) RGD PMID:18206644 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:3654795|PMID:16915281)		 UniProt
RGD		 PMID:16915281 GO_REF:0000024 MGI:3654795 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:15459207) RGD PMID:15459207 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Myocd myocardin IEP RGD PMID:20621093 RGD:5132874 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986 		JBrowse link
G Ndnf neuron-derived neurotrophic factor involved_in ISO (PMID:24706764) RGD PMID:24706764 NCBI chr 4:96,528,830...96,565,780 JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in ISO (PMID:20810912) RGD PMID:20810912 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 IEP RGD PMID:23904790 RGD:10412703 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:21056661) RGD PMID:21056661 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421 		JBrowse link
G Nog noggin IEP RGD PMID:25740156 RGD:12801489 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:22082675 UniProt PMID:22082675 RGD:10047303 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597) RGD PMID:22522597 NCBI chr 1:77,836,522...77,843,991
Ensembl chr 1:77,836,196...77,844,189 		JBrowse link
G Npepps aminopeptidase puromycin sensitive involved_in ISO (PMID:21056661) RGD PMID:21056661 NCBI chr10:85,140,368...85,222,861
Ensembl chr10:85,140,370...85,222,861 		JBrowse link
G Npm1 nucleophosmin 1 IEP RGD PMID:21444791 RGD:11535018 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP RGD PMID:27833818 RGD:12910766 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803 		JBrowse link
G Oprd1 opioid receptor, delta 1 involved_in ISO (PMID:24613828) RGD PMID:24613828 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO (PMID:12095988) RGD PMID:12095988 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987 		JBrowse link
G Palld palladin, cytoskeletal associated protein IEP RGD PMID:16481593 RGD:2325785 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IEP RGD PMID:24177414 RGD:10445837 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IEP RGD PMID:23647599 RGD:10448278 NCBI chr 1:1,734,863...1,767,759
Ensembl chr 1:1,736,276...1,767,618 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in ISO (PMID:11130727) RGD PMID:11130727 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367 		JBrowse link
G Phb2 prohibitin 2 IEP RGD PMID:25031298 RGD:12903263 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:24553947)
(MGI:5558956|PMID:24553947)		 RGD PMID:24553947 MGI:5558956 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415 		JBrowse link
G Plau plasminogen activator, urokinase IEP RGD PMID:19490965 RGD:7241802 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14699081), (PMID:20810912) RGD PMID:14699081 PMID:20810912 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta acts_upstream_of_or_within ISO MGI:106918|MGI:2676890|MGI:3618742 (MGI:5528778|PMID:24011070) RGD PMID:24011070 MGI:5528778 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:22527940 RGD:7242177 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 IEP RGD PMID:17720864 RGD:2316813 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404 		JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of_or_within ISO (MGI:3776183|PMID:18070622) RGD PMID:18070622 MGI:3776183 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:5584033|PMID:24875179) RGD PMID:24875179 MGI:5584033 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832 		JBrowse link
G Ptgis prostaglandin I2 synthase involved_in ISS
ISO		 GO_REF:0000024
(PMID:21296955)		 UniProt
RGD		 PMID:21296955 GO_REF:0000024 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21296955) RGD PMID:21296955 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Ptn pleiotrophin IEP RGD PMID:16226713, PMID:17925408 RGD:9834996, RGD:10044023 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996 		JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19652095) RGD PMID:19652095 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695 		JBrowse link
G RGD1306484 similar to growth and transformation-dependent protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:37,582,678...37,583,232 JBrowse link
G Rnf146 ring finger protein 146 IEP RGD PMID:26218637 RGD:13524866 NCBI chr 1:30,856,923...30,873,814
Ensembl chr 1:30,863,217...30,873,808 		JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (PMID:18658046) RGD PMID:18658046 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6274961|PMID:27763637)		 UniProt
RGD		 PMID:27763637 GO_REF:0000024 MGI:6274961 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458 		JBrowse link
G S100b S100 calcium binding protein B IEP RGD PMID:19910580 RGD:2325647 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 involved_in IDA PMID:28029095 UniProt PMID:28029095 RGD:14390052 NCBI chr 3:51,687,910...51,822,008
Ensembl chr 3:51,687,809...51,822,250 		JBrowse link
G Sdhd succinate dehydrogenase complex subunit D acts_upstream_of_or_within ISO MGI:3526521 (MGI:3525749|PMID:15572694) RGD PMID:15572694 MGI:3525749 NCBI chr 8:55,028,125...55,037,604
Ensembl chr 8:55,028,125...55,037,604 		JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:10590062 RGD:8547811 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:11932307)
GO_REF:0000107		 RGD
Ensembl		 PMID:11932307 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20620956)		 Ensembl
RGD		 PMID:20620956 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24681946)		 UniProt
RGD		 PMID:24681946 GO_REF:0000024 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952 		JBrowse link
G Sirt4 sirtuin 4 IEP RGD PMID:24029877 RGD:9586053 NCBI chr12:46,862,358...46,876,593
Ensembl chr12:46,868,416...46,876,592 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 IEP RGD PMID:21325818 RGD:5688411 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 IEP RGD PMID:10646513 RGD:1598899 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 IDA RGD PMID:20868366 RGD:7349316 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP RGD PMID:17394575 RGD:1642726 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604 		JBrowse link
G Slc8a3 solute carrier family 8 member A3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5693358|PMID:24101730)		 UniProt
RGD		 PMID:24101730 GO_REF:0000024 MGI:5693358 NCBI chr 6:104,889,500...105,099,408
Ensembl chr 6:104,891,376...105,097,054 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 IDA RGD PMID:20868366 RGD:7349316 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:20380727 RGD:2324980 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Stc1 stanniocalcin 1 IEP RGD PMID:15485913 RGD:2324700 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162 		JBrowse link
G Stc2 stanniocalcin 2 IEP RGD PMID:15485913 RGD:2324700 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IDA PMID:19953350 ARUK-UCL PMID:19953350 RGD:13507303 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117 		JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 involved_in ISO (PMID:21402781) RGD PMID:21402781 NCBI chr  X:146,532,002...146,533,538 JBrowse link
G Suv39h1l1 suppressor of variegation 3-9 homolog 1 (Drosophila)-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:15,171,280...15,185,191
Ensembl chr  X:15,171,499...15,185,191 		JBrowse link
G Suv39h2 suppressor of variegation 3-9 homolog 2 involved_in ISO (PMID:21402781) RGD PMID:21402781 NCBI chr17:78,762,897...78,782,016
Ensembl chr17:78,762,991...78,782,016 		JBrowse link
G Tbl2 transducin (beta)-like 2 involved_in ISO (PMID:25393282) RGD PMID:25393282 NCBI chr12:24,565,843...24,578,855
Ensembl chr12:24,565,849...24,578,786 		JBrowse link
G Tert telomerase reverse transcriptase involved_in IEP
ISO		 (PMID:11313459) RGD PMID:11313459, PMID:24376652 RGD:11038675 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:23185017) RGD PMID:23185017 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:20810912) RGD PMID:20810912 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 IEP RGD PMID:19889962 RGD:7247600 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 IEP RGD PMID:19889962 RGD:7247600 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:18297062)
(MGI:5284765|PMID:18297062)		 RGD PMID:18297062 MGI:5284765 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISO
ISS
IEA		 (PMID:12095988)
GO_REF:0000024
GO_REF:0000107		 RGD
BHF-UCL
Ensembl		 PMID:12095988 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844 		JBrowse link
G Ucn2 urocortin 2 IEP RGD PMID:14519439 RGD:2306174 NCBI chr 8:117,727,216...117,728,765
Ensembl chr 8:117,727,877...117,728,764 		JBrowse link
G Ucn3 urocortin 3 IEP RGD PMID:14519439 RGD:2306174 NCBI chr17:69,959,879...69,966,532
Ensembl chr17:69,960,160...69,966,099 		JBrowse link
G Vasn vasorin acts_upstream_of_or_within ISO MGI:5140849 (MGI:5014460|PMID:21658601) RGD PMID:21658601 MGI:5014460 NCBI chr10:11,121,041...11,131,548
Ensembl chr10:11,121,041...11,131,548 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:10575000) RGD PMID:10575000 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vldlr very low density lipoprotein receptor IDA RGD PMID:19233325 RGD:2324641 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISO
ISS		 (PMID:21832157)
GO_REF:0000024		 RGD
UniProt		 PMID:21832157 GO_REF:0000024 NCBI chr 6:103,308,032...103,313,074
Ensembl chr 6:103,308,045...103,313,074 		JBrowse link
hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cybb cytochrome b-245 beta chain IMP RGD PMID:21302291 RGD:11040609 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:60478|PMID:8470821)		 Ensembl
RGD		 PMID:8470821 GO_REF:0000107 MGI:60478 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:21763680)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21763680 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:18718909) RGD PMID:18718909 NCBI chr  X:62,836,131...62,904,114
Ensembl chr  X:62,836,131...62,903,554 		JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
negative regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISO
ISS		 (PMID:17505307)
GO_REF:0000024		 RGD
UniProt		 PMID:17505307 GO_REF:0000024 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 involved_in ISO (PMID:24895913) RGD PMID:24895913 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase IMP RGD PMID:18539296 RGD:9590185 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908 		JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609 		JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IBA
ISO
IDA		 PMID:21873635
(PMID:10037731)
PMID:11231630		 RGD PMID:10037731, PMID:21873635, PMID:11231630 RGD:13792537, RGD:10047348 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP		 PMID:15459207 CAFA PMID:15459207, PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO		 GO_REF:0000107
(MGI:6444553|PMID:30496354)		 Ensembl
RGD		 PMID:30496354 GO_REF:0000107 MGI:6444553 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (MGI:5558956|PMID:24553947) RGD PMID:24553947 MGI:5558956 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IEA		 (PMID:21075086)
GO_REF:0000107		 RGD
Ensembl		 PMID:21075086 GO_REF:0000107 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989 		JBrowse link
negative regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Commd1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO MGI:3714157 (MGI:3713589|PMID:17371845) RGD PMID:17371845 MGI:3713589 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:3608931 (MGI:5618205|PMID:25186293) RGD PMID:25186293 MGI:5618205 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845 		JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISO (PMID:22735262) RGD PMID:22735262 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786 		JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor involved_in IBA
ISO		 PMID:21873635
(PMID:11641274)		 RGD PMID:11641274, PMID:21873635 RGD:13792537 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISO
ISS
IEA		 (PMID:24681946)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:24681946 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:11641274) RGD PMID:11641274 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845 		JBrowse link
positive regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk2 potassium two pore domain channel subfamily K member 2 IMP RGD PMID:24705172 RGD:9831164 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476 		JBrowse link
positive regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rwdd3 RWD domain containing 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:5569907|PMID:22009797)
(PMID:23469069)		 UniProt
RGD		 PMID:22009797 PMID:23469069 GO_REF:0000024 MGI:5569907 NCBI chr 2:224,710,351...224,723,136
Ensembl chr 2:224,710,348...224,723,112 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20889502)		 UniProt
RGD		 PMID:20889502 GO_REF:0000024 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISO
IEA
ISS		 (PMID:24681946)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24681946 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952 		JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19652095), (PMID:22735262), (PMID:24681946)		 UniProt
Ensembl
RGD		 PMID:19652095 PMID:22735262 PMID:24681946 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 involved_in ISO (PMID:24844779) RGD PMID:24844779 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5319604|PMID:18299578)		 UniProt
RGD		 PMID:18299578 GO_REF:0000024 MGI:5319604 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:23303788) RGD PMID:23303788 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:19652095) RGD PMID:19652095 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ajuba ajuba LIM protein involved_in ISO (PMID:22286099) RGD PMID:22286099 NCBI chr15:33,208,210...33,218,456
Ensembl chr15:33,208,216...33,218,456 		JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 involved_in ISO (PMID:23303788) RGD PMID:23303788 NCBI chr 9:101,388,148...101,388,819
Ensembl chr 9:101,388,151...101,388,833 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP RGD PMID:18054269 RGD:9068899 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) RGD PMID:29353861 MGI:6271078 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908 		JBrowse link
G Usp19 ubiquitin specific peptidase 19 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:22128162)		 Ensembl
UniProt
RGD		 PMID:22128162 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:117,280,690...117,291,729
Ensembl chr 8:117,280,705...117,291,351 		JBrowse link
regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bach1 BTB domain and CNC homolog 1 involved_in ISO (PMID:12511571) RGD PMID:12511571 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
Ensembl chr11:27,364,916...27,398,842 		JBrowse link
G Egr1 early growth response 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3847400|PMID:18323529)		 Ensembl
RGD		 PMID:18323529 GO_REF:0000107 MGI:3847400 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Stox1 storkhead box 1 involved_in ISO (PMID:24738702) RGD PMID:24738702 NCBI chr20:32,276,857...32,353,677
Ensembl chr20:32,276,658...32,353,677 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    response to stimulus 10423
      response to stress 4031
        response to hypoxia 438
          cellular response to hypoxia 183
            hypoxia-inducible factor-1alpha signaling pathway + 7
            intrinsic apoptotic signaling pathway in response to hypoxia + 9
            negative regulation of cellular response to hypoxia + 12
            positive regulation of cellular response to hypoxia 1
            positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia 2
            regulation of cellular response to hypoxia + 18
            regulation of transcription from RNA polymerase II promoter in response to hypoxia + 13
Path 2
Term Annotations click to browse term
  biological_process 19634
    cellular process 18481
      cellular response to stimulus 8791
        cellular response to chemical stimulus 3518
          cellular response to oxygen levels 232
            cellular response to decreased oxygen levels 210
              cellular response to hypoxia 183
                hypoxia-inducible factor-1alpha signaling pathway + 7
                intrinsic apoptotic signaling pathway in response to hypoxia + 9
                negative regulation of cellular response to hypoxia + 12
                positive regulation of cellular response to hypoxia 1
                positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia 2
                regulation of cellular response to hypoxia + 18
                regulation of transcription from RNA polymerase II promoter in response to hypoxia + 13
paths to the root