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ONTOLOGY REPORT - ANNOTATIONS


Term:hematopoietic stem cell proliferation
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Accession:GO:0071425 term browser browse the term
Definition:The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.
Synonyms:exact_synonym: hemopoietic stem cell proliferation



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hematopoietic stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ang angiogenin involved_in ISO (PMID:27518564) RGD PMID:27518564 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in ISO (PMID:16118314), (PMID:19340006) RGD PMID:16118314 PMID:19340006 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852
JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 acts_upstream_of_or_within ISO MGI:3994220 (PMID:25636339) RGD PMID:25636339 NCBI chr16:18,068,830...18,074,938
Ensembl chr16:18,068,884...18,074,923
JBrowse link
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2448890 (PMID:16859999)
Ensembl
RGD
PMID:16859999 GO_REF:0000107 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Cd34 CD34 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:21873977)
UniProt
RGD
PMID:21873977 GO_REF:0000024 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha acts_upstream_of ISO MGI:2177135 (PMID:15073037) RGD PMID:15073037 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Ctc1 CST telomere replication complex component 1 acts_upstream_of_or_within ISO MGI:5427642 (PMID:22531781) RGD PMID:22531781 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298
JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (PMID:29925839) RGD PMID:29925839 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO MGI:2183947 (PMID:17554309) RGD PMID:17554309 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Etv6 ETS variant transcription factor 6 involved_in ISO (PMID:25581430) RGD PMID:25581430 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
JBrowse link
G Fubp1 far upstream element binding protein 1 acts_upstream_of_or_within ISO MGI:4335984|MGI:4351702 (PMID:26095368) RGD PMID:26095368 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within_positive_effect ISO (PMID:22665763) RGD PMID:22665763 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Hoxb4 homeo box B4 acts_upstream_of_or_within ISO MGI:3045971 (PMID:14962901) RGD PMID:14962901 NCBI chr10:81,284,552...81,287,134
Ensembl chr10:81,284,552...81,287,128
JBrowse link
G Mecom MDS1 and EVI1 complex locus involved_in ISO (PMID:15889140) RGD PMID:15889140 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Mir143 microRNA 143 acts_upstream_of_or_within_positive_effect ISO MGI:2676830|MGI:5531026 (PMID:29925839) RGD PMID:29925839 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir145 microRNA 145 acts_upstream_of_or_within_positive_effect ISO MGI:2676828|MGI:5531026 (PMID:29925839) RGD PMID:29925839 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Nkap NFKB activating protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176073|MGI:4839023 (PMID:20610818)
Ensembl
RGD
PMID:20610818 GO_REF:0000107 NCBI chr  X:116,373,031...116,392,677
Ensembl chr  X:116,372,839...116,394,945
JBrowse link
G Prg4 proteoglycan 4 acts_upstream_of_or_within ISO MGI:3513195 (PMID:21939632) RGD PMID:21939632 NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119
JBrowse link
G Sart3 spliceosome associated factor 3, U4/U6 recycling protein acts_upstream_of_or_within ISO MGI:5052106 (PMID:21447833) RGD PMID:21447833 NCBI chr12:42,859,026...42,887,041
Ensembl chr12:42,859,305...42,887,038
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:19778523) RGD PMID:19778523 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO MGI:3721903 (PMID:23528453) RGD PMID:23528453 NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of ISO MGI:2447174 (PMID:20032500) RGD PMID:20032500 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:1857930 (PMID:17554309) RGD PMID:17554309 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of
acts_upstream_of_or_within
ISO (PMID:9160667) RGD PMID:9160667 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt10b Wnt family member 10B involved_in
acts_upstream_of_or_within
ISO (PMID:9787155)
(PMID:9160667)
RGD PMID:9160667 PMID:9787155 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
JBrowse link
G Wnt2b Wnt family member 2B involved_in ISO (PMID:9787155) RGD PMID:9787155 NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:9787155)
(PMID:9160667)
GO_REF:0000107
RGD
Ensembl
PMID:9160667 PMID:9787155 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 acts_upstream_of_or_within ISO MGI:2152542 (PMID:17554309) RGD PMID:17554309 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:30065315), (PMID:30150673) RGD PMID:30065315 PMID:30150673 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144
JBrowse link
negative regulation of hematopoietic stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpa CCAAT/enhancer binding protein alpha acts_upstream_of_or_within ISO MGI:2177135 (PMID:15073037) RGD PMID:15073037 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO
GO_REF:0000024
(PMID:21633090)
UniProt
RGD
PMID:21633090 GO_REF:0000024 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:16330772) RGD PMID:16330772 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:16330772) RGD PMID:16330772 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO MGI:2447174 (PMID:20032500) RGD PMID:20032500 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19329776)
UniProt
RGD
PMID:19329776 GO_REF:0000024 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
positive regulation of hematopoietic stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn1l ataxin 1 like acts_upstream_of_or_within ISO MGI:5301616 (PMID:23555280) RGD PMID:23555280 NCBI chr19:37,700,341...37,711,529
Ensembl chr19:37,700,106...37,711,538
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:10725737)
Ensembl
RGD
PMID:10725737 GO_REF:0000107 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISS
ISO
GO_REF:0000024
(PMID:31827282)
UniProt
RGD
PMID:31827282 GO_REF:0000024 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (PMID:21540074) RGD PMID:21540074 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 involved_in ISO (PMID:19506020) RGD PMID:19506020 NCBI chr12:137,342...200,292
Ensembl chr12:103,590...197,784
JBrowse link
G Pdcd2 programmed cell death 2 involved_in ISO (PMID:22922207) RGD PMID:22922207 NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437
JBrowse link
G Thpo thrombopoietin acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(PMID:21540074)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:21540074 GO_REF:0000033 GO_REF:0000107 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Thpol1 thrombopoietin like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (PMID:9160667) RGD PMID:9160667 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:9160667) RGD PMID:9160667 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:9160667)
Ensembl
RGD
PMID:9160667 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
regulation of hematopoietic stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme involved_in IEA
ISO
GO_REF:0000107
(PMID:20116413)
Ensembl
RGD
PMID:20116413 GO_REF:0000107 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23403623)
UniProt
RGD
PMID:23403623 GO_REF:0000024 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Mecom MDS1 and EVI1 complex locus acts_upstream_of_or_within ISO MGI:1857461 (PMID:15889140) RGD PMID:15889140 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:23495171) RGD PMID:23495171 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cell population proliferation 2267
        stem cell proliferation 156
          hematopoietic stem cell proliferation 44
            negative regulation of hematopoietic stem cell proliferation 6
            positive regulation of hematopoietic stem cell proliferation 11
            regulation of hematopoietic stem cell proliferation + 21
Path 2
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cellular developmental process 4812
        cell differentiation 4811
          cell development 3339
            hemopoiesis 1079
              hematopoietic stem cell proliferation 44
                negative regulation of hematopoietic stem cell proliferation 6
                positive regulation of hematopoietic stem cell proliferation 11
                regulation of hematopoietic stem cell proliferation + 21
paths to the root