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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to interleukin-1
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Accession:GO:0071347 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
Synonyms:exact_synonym: cellular response to IL-1


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cellular response to interleukin-1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07054614.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Abcc2 ATP binding cassette subfamily C member 2 IEP RGD PMID:20702406 RGD:11081005 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5489057|PMID:19014335) RGD PMID:19014335 MGI:5489057 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Actr3 actin related protein 3 IEP RGD PMID:21191089 RGD:11571626 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:18485748) RGD PMID:18485748 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 involved_in ISO (PMID:18485748) RGD PMID:18485748 NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328 		JBrowse link
G Akap12 A-kinase anchoring protein 12 IEP RGD PMID:20454828 RGD:14348957 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 involved_in ISO
IEA		 (PMID:7730328)
GO_REF:0000107		 RGD
Ensembl		 PMID:7730328 GO_REF:0000107 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Apoe apolipoprotein E IEP RGD PMID:22171672 RGD:6903907 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:22449442 RGD:8695996 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Bcl2l1 Bcl2-like 1 IEP plus interferon-gamma RGD PMID:20798690 RGD:11353801 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger IEP RGD PMID:22706317 RGD:7240518 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Bysl bystin-like IEP IL-1 beta RGD PMID:15305856 RGD:2316201 NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Camp cathelicidin antimicrobial peptide IEP IL-1beta RGD PMID:19879657 RGD:2316237 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in IEP
ISO
IBA		 (MGI:3699670|PMID:14662900)
PMID:21873635
(PMID:9407497)		 RGD PMID:9407497 PMID:14662900 PMID:14512159 PMID:21873635 MGI:3699670, RGD:8548859, RGD:13792537 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO
IBA		 (PMID:9407497)
PMID:21873635		 RGD PMID:9407497 PMID:21873635 RGD:13792537 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in IBA
ISO		 PMID:21873635
(PMID:9407497)		 RGD PMID:9407497 PMID:21873635 RGD:13792537 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,380,185...68,385,859
Ensembl chr10:68,380,188...68,384,001 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Cd40 CD40 molecule involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:10403401 PMID:21873635 RGD:634252, RGD:13792537 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd47 Cd47 molecule involved_in IMP PMID:12023387 ARUK-UCL PMID:12023387 RGD:625650 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta IDA RGD PMID:18405661 RGD:10401220 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cfl1 cofilin 1 IDA RGD PMID:24760020 RGD:11570414 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Chi3l1 chitinase 3 like 1 IEP IL-1beta RGD PMID:16234240 RGD:4892601 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP RGD PMID:16239643 RGD:5135237 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:9582502 PMID:9397943 RGD:4891986, RGD:4891988 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA
ISS		 (PMID:19948740)
GO_REF:0000107
(MGI:4453088|PMID:19948740)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19948740 GO_REF:0000024 GO_REF:0000107 MGI:4453088 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Edn1 endothelin 1 IEP RGD PMID:20512083 RGD:4144864 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:18315570 RGD:2312264 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epas1 endothelial PAS domain protein 1 IEP RGD PMID:12099714 RGD:11041576 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Fas Fas cell surface death receptor IEP RGD PMID:10678925 RGD:8662912 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgb fibrinogen beta chain IEP RGD PMID:17521427 RGD:7175504 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain IEP RGD PMID:11071643 RGD:731198 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fn1 fibronectin 1 IMP RGD PMID:12679595 RGD:7205467 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:17266443) RGD PMID:17266443 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gbp2 guanylate binding protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17266443)		 Ensembl
RGD		 PMID:17266443 GO_REF:0000107 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp3 guanylate binding protein 3 involved_in ISO (PMID:17266443) RGD PMID:17266443 NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098 		JBrowse link
G Has2 hyaluronan synthase 2 involved_in ISO (PMID:20522558) RGD PMID:20522558 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 IEP RGD PMID:23589286 RGD:9685382 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEP
IEA
ISO		 GO_REF:0000107
(PMID:12958148)		 Ensembl
RGD		 PMID:12958148 PMID:12101082 GO_REF:0000107, RGD:9068871 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 IEP RGD PMID:16354107 RGD:2316792 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 IEP RGD PMID:15621568 RGD:6784519 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18390475)		 UniProt
Ensembl
RGD		 PMID:18390475 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in ISO
IEA
ISS		 (PMID:18390475)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18390475 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Hyal3 hyaluronidase 3 involved_in ISO (PMID:18390475) RGD PMID:18390475 NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:20643106 RGD:4145376 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit IEP RGD PMID:9473516 RGD:12910942 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677 		JBrowse link
G Il17a interleukin 17A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4355633|PMID:19666510)		 Ensembl
RGD		 PMID:19666510 GO_REF:0000107 MGI:4355633 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within IEP
ISO		 (MGI:4415769|PMID:19955433) RGD PMID:19955433 PMID:2121800 MGI:4415769, RGD:7829782 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhbb inhibin subunit beta B IEP RGD PMID:15817831 RGD:9743911 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Irf1 interferon regulatory factor 1 IDA RGD PMID:19843519 RGD:5128776 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Klf2 KLF transcription factor 2 IEP RGD PMID:18406357 RGD:2316543 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Kmo kynurenine 3-monooxygenase IEP RGD PMID:25675848 RGD:13513907 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Lcn2 lipocalin 2 IEP IL-1beta RGD PMID:19329498 PMID:22249220 RGD:2316495, RGD:126781756 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA		 (MGI:1101248|PMID:9405446)
GO_REF:0000107		 RGD
Ensembl		 PMID:9405446 GO_REF:0000107 MGI:1101248 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 involved_in ISO (PMID:8663524) RGD PMID:8663524 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 involved_in ISO
IEA		 (PMID:9218798)
GO_REF:0000107		 RGD
Ensembl		 PMID:9218798 GO_REF:0000107 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEP RGD PMID:9513050 RGD:10412698 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEP Interleukin-1 beta RGD PMID:10593906 PMID:9513050 RGD:2304240, RGD:10412698 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP Il1-alpha RGD PMID:22410640 RGD:7207278 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP Il-1beta RGD PMID:20371087 PMID:16046515 RGD:2325687, RGD:2313720 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP Il-1beta RGD PMID:16046515 RGD:2313720 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP Il-1beta RGD PMID:20145375 PMID:16046515 RGD:2325789, RGD:2313720 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Muc19 mucin 19, oligomeric ISO RGD RGD:11554183 RGD:150520179 NCBI chr 7:123,017,896...123,139,053
Ensembl chr 7:123,017,896...123,139,053 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO RGD RGD:11554332 RGD:150520179 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP IL-1beta RGD PMID:22706317 RGD:7240518 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in ISO (PMID:18390750) RGD PMID:18390750 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:12958148)		 Ensembl
RGD		 PMID:12958148 PMID:17726227 GO_REF:0000107, RGD:10045667 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:18757402) RGD PMID:18757402 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nos2 nitric oxide synthase 2 IEP RGD PMID:22001142 RGD:5508716 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox1 NADPH oxidase 1 IEP RGD PMID:26682942 RGD:329961560 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nox4 NADPH oxidase 4 IEP RGD PMID:26682942 RGD:329961560 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6162161|PMID:29533925)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:29533925 GO_REF:0000024 GO_REF:0000107 MGI:6162161 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 IEP RGD PMID:22279542 RGD:7175260 NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483 		JBrowse link
G P2ry2 purinergic receptor P2Y2 IEP RGD PMID:19317852 RGD:2316656 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP RGD PMID:23775412 RGD:9835367 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IEP RGD PMID:18335579 RGD:10445832 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:7546776 RGD:10449507 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit IEP RGD PMID:16830232 RGD:8693738 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 IEP RGD PMID:22612225 RGD:9850286 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IEP RGD PMID:16405508 RGD:9850258 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IEP RGD PMID:11207665 RGD:10043377 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptgis prostaglandin I2 synthase involved_in ISO
IEA
ISS		 (PMID:8185632)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:8185632 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:12486103) RGD PMID:12486103 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rbmx RNA binding motif protein, X-linked involved_in ISO (PMID:18445477) RGD PMID:18445477 NCBI chr  X:135,305,237...135,314,806
Ensembl chr  X:135,305,325...135,314,743 		JBrowse link
G Rbmxl1 Rbmx like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:29,407,902...29,411,519
Ensembl chr19:29,407,912...29,412,859 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:18073330) RGD PMID:18073330 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rora RAR-related orphan receptor A acts_upstream_of_or_within ISO (MGI:4415769|PMID:19955433) RGD PMID:19955433 MGI:4415769 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N IEP RGD PMID:10547273 RGD:5147417 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpine1 serpin family E member 1 IDA RGD PMID:9420877 RGD:8547942 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:16149051)
GO_REF:0000107		 RGD
Ensembl		 PMID:16149051 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sirpa signal-regulatory protein alpha involved_in IMP PMID:12023387 ARUK-UCL PMID:12023387 RGD:625650 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IEP RGD PMID:17693623 RGD:10042964 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:20079164) RGD PMID:20079164 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tank TRAF family member-associated NFKB activator involved_in ISO (PMID:25861989) RGD PMID:25861989 NCBI chr 3:46,114,230...46,190,270
Ensembl chr 3:46,114,274...46,190,264 		JBrowse link
G Tfpi tissue factor pathway inhibitor IEP RGD PMID:11816723 RGD:727341 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:25861989)		 UniProt
Ensembl
RGD		 PMID:25861989 GO_REF:0000024 GO_REF:0000107 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
G Vldlr very low density lipoprotein receptor IEP IL-1beta RGD PMID:16376325 RGD:1625574 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
G Xdh xanthine dehydrogenase IEP RGD PMID:12653206 RGD:1624380 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Yy1 YY1 transcription factor IDA RGD PMID:10860774 RGD:9588259 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20018936)		 Ensembl
RGD		 PMID:20018936 GO_REF:0000107 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:25816133)		 Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1a interleukin 1 alpha acts_upstream_of_or_within ISO (MGI:5468848|PMID:23395675) RGD PMID:23395675 MGI:5468848 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:1919436), (PMID:25327529), (PMID:28331908), (PMID:2950091), (PMID:32719155), (PMID:33377178) RGD PMID:1919436 PMID:2950091 PMID:25327529 PMID:28331908 PMID:32719155 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in IMP
IBA
ISO
IEA		 PMID:21873635
(PMID:10383454), (PMID:2950091)
(MGI:1889886|PMID:10854325)
GO_REF:0000108		 RGD
GOC		 PMID:2950091 PMID:10383454 PMID:10854325 PMID:20967881 PMID:21873635 GO_REF:0000108 MGI:1889886, RGD:5130945, RGD:13792537 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:9065432)		 Ensembl
RGD		 PMID:9065432 GO_REF:0000107 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 NOT|involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11397809)
(PMID:10383454), (PMID:14625308)
PMID:21873635
(MGI:1889886|PMID:10854325)
(MGI:2181508|PMID:12054681)		 RGD PMID:10383454 PMID:10854325 PMID:11397809 PMID:12054681 PMID:14625308 More... MGI:1889886 MGI:2181508, RGD:13792537 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in IBA
ISO		 PMID:21873635
(PMID:10383454)		 RGD PMID:10383454 PMID:21873635 RGD:13792537 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10383454)
(MGI:2181508|PMID:12054681)
PMID:21873635		 RGD PMID:10383454 PMID:12054681 PMID:21873635 MGI:2181508, RGD:13792537 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 involved_in ISO (PMID:20485341) RGD PMID:20485341 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:20018936) RGD PMID:20018936 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mir146a microRNA 146a involved_in ISO (PMID:20937840) RGD PMID:20937840 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (MGI:1889886|PMID:10854325)
(PMID:9430229)		 RGD PMID:9430229 PMID:10854325 MGI:1889886 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:26020802) RGD PMID:26020802 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:8872139)		 Ensembl
RGD		 PMID:8872139 GO_REF:0000107 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 involved_in ISO (PMID:20018936) RGD PMID:20018936 NCBI chr 1:204,021,805...204,032,781
Ensembl chr 1:204,021,806...204,032,761 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 involved_in ISO (PMID:20018936) RGD PMID:20018936 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224 		JBrowse link
G St18 ST18 C2H2C-type zinc finger transcription factor involved_in ISO
IEA		 (PMID:18676404)
GO_REF:0000107		 RGD
Ensembl		 PMID:18676404 GO_REF:0000107 NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790 		JBrowse link
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (MGI:2149909|PMID:11544529) RGD PMID:11544529 MGI:2149909 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) RGD PMID:16633345 MGI:3656197 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Tollip toll interacting protein involved_in ISO (MGI:1889886|PMID:10854325)
(PMID:10854325)		 RGD PMID:10854325 MGI:1889886 NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IMP
IEA
ISO		 GO_REF:0000107
(MGI:2181820|PMID:10421844)		 Ensembl
RGD		 PMID:10421844 PMID:20967881 GO_REF:0000107 MGI:2181820, RGD:5130945 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
negative regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
PR:000045525 (MGI:5468848|PMID:23395675)		 Ensembl
RGD		 PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rn interleukin 1 receptor antagonist involved_in ISO
IEA
IBA		 (PMID:2137200), (PMID:2139180)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:2137200 PMID:2139180 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mir21 microRNA 21 acts_upstream_of_or_within ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir27a microRNA 27a involved_in ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO
IBA		 (PMID:29395066)
(MGI:6120140|PMID:29395066)
PMID:21873635		 RGD PMID:29395066 PMID:21873635 MGI:6120140, RGD:13792537 NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
positive regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r1 interleukin 1 receptor type 1 acts_upstream_of_or_within ISO PR:000045524 (MGI:5468848|PMID:23395675) RGD PMID:23395675 MGI:5468848 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vrk2 VRK serine/threonine kinase 2 involved_in ISO (PMID:18286207) RGD PMID:18286207 NCBI chr14:100,313,771...100,434,520
Ensembl chr14:100,313,601...100,434,527 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6394181|PMID:31630209)		 UniProt
RGD		 PMID:31630209 GO_REF:0000024 MGI:6394181 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19527
    response to stimulus 10386
      response to chemical 5926
        response to organic substance 3757
          response to cytokine 1201
            response to interleukin-1 179
              cellular response to interleukin-1 144
                interleukin-1-mediated signaling pathway + 31
paths to the root