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ONTOLOGY REPORT - ANNOTATIONS

Term:L-methionine biosynthetic process
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Accession:GO:0071265 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.
Synonyms:exact_synonym: L-methionine anabolism;   L-methionine biosynthesis;   L-methionine formation;   L-methionine synthesis


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'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IMP (PMID:10529246) UniProt PMID:10529246 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IDA
IBA		 (PMID:18230605)
(PMID:21873635)		 BHF-UCL
GO_Central		 PMID:18230605 PMID:21873635 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IDA
IBA		 (PMID:18230605)
(PMID:21873635)		 BHF-UCL
GO_Central		 PMID:18230605 PMID:21873635 NCBI chr 5:79,069,767...79,090,069
Ensembl chr 5:79,069,767...79,090,069 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IDA
IEA		 (PMID:15938715) UniProt
InterPro		 PMID:15938715 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 NCBI chr 2:3,497,366...3,519,531
Ensembl chr 2:3,497,366...3,519,531 		JBrowse link
G APIP APAF1 interacting protein involved_in IEA
IBA
IMP		 (PMID:21873635)
(PMID:22837397), (PMID:23285211)		 UniProt
GO_Central
InterPro		 PMID:21873635 PMID:22837397 PMID:23285211 GO_REF:0000002 GO_REF:0000041 NCBI chr11:34,882,295...34,916,379
Ensembl chr11:34,853,094...34,916,379 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA
IDA
IBA		 (PMID:15843022)
(PMID:21873635)		 UniProt
GO_Central
InterPro		 PMID:15843022 PMID:21873635 GO_REF:0000002 GO_REF:0000041 NCBI chr 4:82,430,590...82,461,177
Ensembl chr 4:82,430,590...82,461,177 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in TAS
IBA
IEA		 (PMID:21873635) Reactome
GO_Central
UniProt		 PMID:21873635 GO_REF:0000041 Reactome:R-HSA-1237112 NCBI chr19:13,764,522...13,774,282
Ensembl chr19:13,764,522...13,774,282 		JBrowse link
G MTAP methylthioadenosine phosphorylase involved_in IEA
IBA		 (PMID:21873635) UniProt
GO_Central		 PMID:21873635 GO_REF:0000041 GO_REF:0000104 NCBI chr 9:21,802,636...21,941,115
Ensembl chr 9:21,802,636...21,937,651 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chr11:34,882,295...34,916,379
Ensembl chr11:34,853,094...34,916,379 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:82,430,590...82,461,177
Ensembl chr 4:82,430,590...82,461,177 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr19:13,764,522...13,774,282
Ensembl chr19:13,764,522...13,774,282 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19555
    metabolic process 12588
      cellular metabolic process 11257
        sulfur compound metabolic process 342
          sulfur compound biosynthetic process 166
            sulfur amino acid biosynthetic process 17
              methionine biosynthetic process 12
                L-methionine biosynthetic process 7
                  'de novo' L-methionine biosynthetic process + 1
                  L-methionine salvage + 7
Path 2
Term Annotations click to browse term
  biological_process 19555
    metabolic process 12588
      cellular metabolic process 11257
        organic acid metabolic process 1088
          oxoacid metabolic process 1080
            carboxylic acid metabolic process 1056
              amino acid metabolic process 315
                alpha-amino acid metabolic process 228
                  aspartate family amino acid metabolic process 50
                    methionine metabolic process 16
                      methionine biosynthetic process 12
                        L-methionine biosynthetic process 7
                          'de novo' L-methionine biosynthetic process + 1
                          L-methionine salvage + 7
paths to the root