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ONTOLOGY REPORT - ANNOTATIONS


Term:WASH complex
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Accession:GO:0071203 term browser browse the term
Definition:A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.


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WASH complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 ISO
ISS
(PMID:19922875)
GO_REF:0000024
RGD
UniProt
PMID:19922875 GO_REF:0000024 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta ISO
ISS
(PMID:19922875)
GO_REF:0000024
RGD
UniProt
PMID:19922875 GO_REF:0000024 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 colocalizes_with ISO (PMID:24643499) RGD PMID:24643499 NCBI chr 8:112,697,907...112,830,445
Ensembl chr 8:112,698,348...112,807,598
JBrowse link
G Snx27 sorting nexin 27 colocalizes_with IEA
ISO
ISS
GO_REF:0000107
(PMID:21602791), (PMID:23563491)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21602791, PMID:23563491 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:195,738,613...195,821,608
Ensembl chr 2:195,738,619...195,821,608
JBrowse link
G Tbc1d23 TBC1 domain family, member 23 colocalizes_with ISO (PMID:29084197)
(MGI:MGI:5920698|PMID:29084197)
RGD PMID:29084197 MGI:MGI:5920698 NCBI chr11:45,401,396...45,459,841
Ensembl chr11:45,401,403...45,459,821
JBrowse link
G Washc1 WASH complex subunit 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:5806548|PMID:26965651), (MGI:MGI:5883184|PMID:27390154)
GO_REF:0000024
(PMID:19922875)
Ensembl
RGD
UniProt
PMID:19922875, PMID:26965651, PMID:27390154 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5806548, MGI:MGI:5883184 NCBI chr 9:113,918,914...113,936,861
Ensembl chr 9:113,918,858...113,936,860
JBrowse link
G Washc2c WASH complex subunit 2C ISO
IEA
ISS
(PMID:19922875)
(MGI:MGI:5883184|PMID:27390154)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19922875, PMID:27390154 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5883184 NCBI chr 4:148,139,512...148,197,363
Ensembl chr 4:148,139,528...148,197,365
JBrowse link
G Washc3 WASH complex subunit 3 ISO
IBA
(PMID:19922875)
(MGI:MGI:5883184|PMID:27390154)
PMID:21873635
RGD PMID:19922875, PMID:27390154, PMID:21873635 MGI:MGI:5883184, RGD:13792537 NCBI chr 7:28,762,417...28,809,286
Ensembl chr 7:28,762,417...28,809,280
JBrowse link
G Washc4 WASH complex subunit 4 ISO
IBA
(PMID:19922875)
(MGI:MGI:5883184|PMID:27390154)
PMID:21873635
RGD PMID:19922875, PMID:27390154, PMID:21873635 MGI:MGI:5883184, RGD:13792537 NCBI chr 7:26,309,279...26,361,221
Ensembl chr 7:26,311,094...26,361,221
JBrowse link
G Washc5 WASH complex subunit 5 ISO (PMID:19922875)
(MGI:MGI:5883184|PMID:27390154)
RGD PMID:19922875, PMID:27390154 MGI:MGI:5883184 NCBI chr 7:99,625,379...99,677,237
Ensembl chr 7:99,625,619...99,677,268
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6092
      WASH complex 10
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      intracellular anatomical structure 14706
        cytoplasm 11457
          WASH complex 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.