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ONTOLOGY REPORT - ANNOTATIONS

Term:SMAD protein complex
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Accession:GO:0071141 term browser browse the term
Definition:A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.
Synonyms:exact_synonym: SMAD complex


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SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga2 high mobility group AT-hook 2 part_of ISS
ISO		 GO_REF:0000024
(PMID:18832382)		 UniProt
RGD		 PMID:18832382 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Smad2 SMAD family member 2 part_of ISO (PMID:18832382) RGD PMID:18832382 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 part_of ISO
ISS		 (PMID:18832382), (PMID:21947082)
GO_REF:0000024		 RGD
UniProt		 PMID:18832382 PMID:21947082 GO_REF:0000024 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 part_of ISO (PMID:10647180), (PMID:18832382) RGD PMID:10647180 PMID:18832382 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Snw1 SNW domain containing 1 IDA RGD PMID:17592128 RGD:2306466 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
heteromeric SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad1 SMAD family member 1 part_of IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:11779505)		 Ensembl
GO_Central
RGD		 PMID:11779505 GO_REF:0000033 GO_REF:0000107 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad2 SMAD family member 2 part_of IBA
ISO		 GO_REF:0000033
(PMID:15350224), (PMID:21828274)		 GO_Central
RGD		 PMID:15350224 PMID:21828274 GO_REF:0000033 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 part_of ISO
IBA		 (PMID:21828274)
GO_REF:0000033		 RGD
GO_Central		 PMID:21828274 GO_REF:0000033 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 part_of IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:11779505), (PMID:15350224)		 Ensembl
GO_Central
RGD		 PMID:11779505 PMID:15350224 GO_REF:0000033 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad5 SMAD family member 5 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634 		JBrowse link
G Smad6 SMAD family member 6 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Smad7 SMAD family member 7 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smad9 SMAD family member 9 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
homomeric SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad1 SMAD family member 1 part_of IEA
ISO		 GO_REF:0000107
(PMID:11779505)
(MGI:5014035|PMID:20147459)		 Ensembl
RGD		 PMID:11779505 PMID:20147459 GO_REF:0000107 MGI:5014035 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad2 SMAD family member 2 part_of ISO (PMID:11779503) RGD PMID:11779503 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20814
    protein-containing complex 6438
      SMAD protein complex 10
        heteromeric SMAD protein complex 8
        homomeric SMAD protein complex 2
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