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ONTOLOGY REPORT - ANNOTATIONS


Term:SMAD protein complex
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Accession:GO:0071141 term browser browse the term
Definition:A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.
Synonyms:exact_synonym: SMAD complex



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SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga2 high mobility group AT-hook 2 part_of ISS
ISO
GO_REF:0000024
(PMID:18832382)
UniProt
RGD
PMID:18832382 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Smad2 SMAD family member 2 part_of ISO (PMID:18832382) RGD PMID:18832382 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 part_of ISO
ISS
(PMID:18832382), (PMID:21947082)
GO_REF:0000024
RGD
UniProt
PMID:18832382 PMID:21947082 GO_REF:0000024 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 part_of ISO
IEA
(PMID:10647180), (PMID:18832382)
GO_REF:0000107
RGD
Ensembl
PMID:10647180 PMID:18832382 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Snw1 SNW domain containing 1 IDA RGD PMID:17592128 RGD:2306466 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
heteromeric SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad1 SMAD family member 1 part_of
located_in
IBA
ISO
PMID:21873635
(PMID:11779505)
RGD PMID:11779505 PMID:21873635 RGD:13792537 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad2 SMAD family member 2 part_of
located_in
ISO
IBA
(PMID:21828274)
(PMID:15350224)
PMID:21873635
RGD PMID:15350224 PMID:21828274 PMID:21873635 RGD:13792537 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 part_of
located_in
IBA
ISO
PMID:21873635
(PMID:15350224)
(PMID:21828274)
RGD PMID:15350224 PMID:21828274 PMID:21873635 RGD:13792537 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 part_of
located_in
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:11779505), (PMID:15350224)
Ensembl
RGD
PMID:11779505 PMID:15350224 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smad5 SMAD family member 5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
JBrowse link
G Smad6 SMAD family member 6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smad9 SMAD family member 9 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307
JBrowse link
homomeric SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad1 SMAD family member 1 located_in ISO (PMID:11779505)
(MGI:5014035|PMID:20147459)
RGD PMID:11779505 PMID:20147459 MGI:5014035 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad2 SMAD family member 2 located_in
part_of
ISO
IEA
(PMID:11779503)
GO_REF:0000107
RGD
Ensembl
PMID:11779503 GO_REF:0000107 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19969
    protein-containing complex 6165
      SMAD protein complex 10
        heteromeric SMAD protein complex 8
        homomeric SMAD protein complex 2
paths to the root