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ONTOLOGY REPORT - ANNOTATIONS


Term:SMAD protein complex
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Accession:GO:0071141 term browser browse the term
Definition:A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.
Synonyms:exact_synonym: SMAD complex


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SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmga2 high mobility group AT-hook 2 part_of ISS
ISO
GO_REF:0000024
(PMID:18832382)
UniProt
RGD
PMID:18832382 GO_REF:0000024 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Smad2 SMAD family member 2 part_of ISO (PMID:18832382) RGD PMID:18832382 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 part_of ISO
ISS
(PMID:18832382), (PMID:21947082)
GO_REF:0000024
RGD
UniProt
PMID:18832382 PMID:21947082 GO_REF:0000024 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 part_of ISO
IEA
(PMID:10647180), (PMID:18832382)
GO_REF:0000107
RGD
Ensembl
PMID:10647180 PMID:18832382 GO_REF:0000107 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Snw1 SNW domain containing 1 IDA RGD PMID:17592128 RGD:2306466 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
heteromeric SMAD protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad1 SMAD family member 1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad2 SMAD family member 2 part_of ISO
IBA
(PMID:21828274)
PMID:21873635
RGD PMID:21828274, PMID:21873635 RGD:13792537 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 part_of IBA
ISO
PMID:21873635
(PMID:21828274)
RGD PMID:21828274, PMID:21873635 RGD:13792537 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad5 SMAD family member 5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:8,307,448...8,336,996
Ensembl chr17:8,311,796...8,331,032
JBrowse link
G Smad6 SMAD family member 6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Smad7 SMAD family member 7 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smad9 SMAD family member 9 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      SMAD protein complex 10
        heteromeric SMAD protein complex 8
        homomeric SMAD protein complex 0
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