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ONTOLOGY REPORT - ANNOTATIONS


Term:polyadenylation-dependent mRNA catabolic process
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Accession:GO:0071047 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
Synonyms:related_synonym: poly(A)-dependent mRNA catabolic process


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nuclear polyadenylation-dependent mRNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Exosc7 exosome component 7 JBrowse link 8 132,204,628 132,229,968 RGD:13792537
G Exosc8 exosome component 8 JBrowse link 2 143,925,643 143,932,240 RGD:13792537
G Exosc9 exosome component 9 JBrowse link 2 123,264,679 123,275,623 RGD:13792537
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 14 113,530,470 113,561,645 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    negative regulation of biological process 5617
      negative regulation of metabolic process 3227
        negative regulation of macromolecule metabolic process 2957
          negative regulation of gene expression 2076
            mRNA catabolic process 225
              polyadenylation-dependent mRNA catabolic process 4
                nuclear polyadenylation-dependent mRNA catabolic process 4
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      cellular metabolic process 10918
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              RNA metabolic process 4347
                RNA catabolic process 261
                  mRNA catabolic process 225
                    polyadenylation-dependent mRNA catabolic process 4
                      nuclear polyadenylation-dependent mRNA catabolic process 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.