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ONTOLOGY REPORT - ANNOTATIONS


Term:catalytic step 1 spliceosome
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Accession:GO:0071012 term browser browse the term
Definition:A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
Synonyms:exact_synonym: activated spliceosome
 narrow_synonym: mammalian spliceosomal complex B*;   mammalian spliceosomal complex B2;   yeast spliceosomal complex A1



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U2-type catalytic step 1 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casc3 CASC3 exon junction complex subunit part_of ISS
ISO
GO_REF:0000024
(PMID:29301961)
UniProt
RGD
PMID:29301961 GO_REF:0000024 NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966
JBrowse link
G Cwc22 CWC22 spliceosome associated protein part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228
JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 part_of ISO
ISS
(PMID:29301961)
GO_REF:0000024
RGD
UniProt
PMID:29301961 GO_REF:0000024 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
G Isy1 ISY1 splicing factor homolog part_of ISS
ISO
GO_REF:0000024
(PMID:29301961)
UniProt
RGD
PMID:29301961 GO_REF:0000024 NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188
JBrowse link
G Magohb mago homolog B, exon junction complex subunit part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr 4:165,034,131...165,041,977
Ensembl chr 4:165,034,122...165,041,967
JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606
JBrowse link
G Rbm22 RNA binding motif protein 22 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569
JBrowse link
G Rbm8a RNA binding motif protein 8A part_of ISS
ISO
GO_REF:0000024
(PMID:29301961)
UniProt
RGD
PMID:29301961 GO_REF:0000024 NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959
JBrowse link
G RGD1560857 similar to RIKEN cDNA 2900016D05 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:21,108,807...21,109,887
Ensembl chr16:21,108,942...21,109,883
JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 part_of ISS
ISO
IEA
GO_REF:0000024
(PMID:29301961)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29301961 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182
JBrowse link
G Yju2 YJU2 splicing factor part_of ISO
IBA
(PMID:29301961)
PMID:21873635
RGD PMID:29301961 PMID:21873635 RGD:13792537 NCBI chr 9:789,603...799,505
Ensembl chr 9:789,606...799,496
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20534
    protein-containing complex 6321
      catalytic complex 1869
        catalytic step 1 spliceosome 13
          U12-type catalytic step 1 spliceosome 0
          U2-type catalytic step 1 spliceosome 13
Path 2
Term Annotations click to browse term
  cellular_component 20534
    cellular anatomical entity 20291
      organelle 13525
        membrane-bounded organelle 12075
          intracellular membrane-bounded organelle 11565
            nucleus 7215
              nuclear protein-containing complex 1283
                spliceosomal complex 211
                  catalytic step 1 spliceosome 13
                    U12-type catalytic step 1 spliceosome 0
                    U2-type catalytic step 1 spliceosome 13
paths to the root