ONTOLOGY REPORT - ANNOTATIONS
Term: catalytic step 1 spliceosome
Accession: GO:0071012
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Definition: A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
Synonyms: exact_synonym: activated spliceosome
narrow_synonym: mammalian spliceosomal complex B*; mammalian spliceosomal complex B2; yeast spliceosomal complex A1
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Casc3
CASC3 exon junction complex subunit
part_of
ISS ISO
GO_REF:0000024 (PMID:29301961)
UniProt RGD
PMID:29301961
GO_REF:0000024
NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966
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Cwc22
CWC22 spliceosome associated protein
part_of
ISO
(PMID:29301961)
RGD
PMID:29301961
NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228
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Cwc25
CWC25 spliceosome-associated protein homolog
part_of
ISO
(PMID:29301961)
RGD
PMID:29301961
NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354
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Eif4a3
eukaryotic translation initiation factor 4A3
part_of
ISO ISS
(PMID:29301961) GO_REF:0000024
RGD UniProt
PMID:29301961
GO_REF:0000024
NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
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Isy1
ISY1 splicing factor homolog
part_of
ISS ISO
GO_REF:0000024 (PMID:29301961)
UniProt RGD
PMID:29301961
GO_REF:0000024
NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188
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Magohb
mago homolog B, exon junction complex subunit
part_of
ISO
(PMID:29301961)
RGD
PMID:29301961
NCBI chr 4:165,034,131...165,041,977
Ensembl chr 4:165,034,122...165,041,967
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Prpf19
pre-mRNA processing factor 19
part_of
IBA
PMID:21873635
GO_Central
PMID:21873635
RGD:13792537
NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
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Prpf8
pre-mRNA processing factor 8
part_of
ISO
(PMID:29301961)
RGD
PMID:29301961
NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606
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Rbm22
RNA binding motif protein 22
part_of
IBA
PMID:21873635
GO_Central
PMID:21873635
RGD:13792537
NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569
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Rbm8a
RNA binding motif protein 8A
part_of
ISS ISO
GO_REF:0000024 (PMID:29301961)
UniProt RGD
PMID:29301961
GO_REF:0000024
NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959
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RGD1560857
similar to RIKEN cDNA 2900016D05
part_of
IBA
PMID:21873635
GO_Central
PMID:21873635
RGD:13792537
NCBI chr16:21,108,807...21,109,887
Ensembl chr16:21,108,942...21,109,883
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Snrnp200
small nuclear ribonucleoprotein U5 subunit 200
part_of
ISS ISO IEA
GO_REF:0000024 (PMID:29301961) GO_REF:0000107
UniProt RGD Ensembl
PMID:29301961
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182
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Yju2
YJU2 splicing factor
part_of
ISO IBA
(PMID:29301961) PMID:21873635
RGD
PMID:29301961 PMID:21873635
RGD:13792537
NCBI chr 9:789,603...799,505
Ensembl chr 9:789,606...799,496
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