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ONTOLOGY REPORT - ANNOTATIONS

Term:catalytic step 1 spliceosome
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Accession:GO:0071012 term browser browse the term
Definition:A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
Synonyms:exact_synonym: activated spliceosome
 narrow_synonym: mammalian spliceosomal complex B*;   mammalian spliceosomal complex B2;   yeast spliceosomal complex A1


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U2-type catalytic step 1 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07024964.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:21,108,942...21,109,883 JBrowse link
G Casc3 CASC3 exon junction complex subunit part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:29301961)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:29301961 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966 		JBrowse link
G Cwc22 CWC22 spliceosome associated protein homolog part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228 		JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 part_of ISO
ISS		 (PMID:29301961)
GO_REF:0000024		 RGD
UniProt		 PMID:29301961 GO_REF:0000024 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
G Isy1 ISY1 splicing factor homolog part_of ISS
ISO		 GO_REF:0000024
(PMID:29301961)		 UniProt
RGD		 PMID:29301961 GO_REF:0000024 NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188 		JBrowse link
G Magohb mago homolog B, exon junction complex subunit part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr 4:165,034,131...165,041,977
Ensembl chr 4:165,034,122...165,041,967 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO (PMID:29301961) RGD PMID:29301961 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606 		JBrowse link
G Rbm22 RNA binding motif protein 22 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569 		JBrowse link
G Rbm8a RNA binding motif protein 8A part_of ISS
ISO		 GO_REF:0000024
(PMID:29301961)		 UniProt
RGD		 PMID:29301961 GO_REF:0000024 NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29301961)		 UniProt
Ensembl
RGD		 PMID:29301961 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Yju2 YJU2 splicing factor homolog part_of IBA
ISO		 PMID:21873635
(PMID:29301961)		 RGD PMID:29301961 PMID:21873635 RGD:13792537 NCBI chr 9:789,603...799,505
Ensembl chr 9:789,606...799,496 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      catalytic complex 1450
        catalytic step 1 spliceosome 13
          U12-type catalytic step 1 spliceosome 0
          U2-type catalytic step 1 spliceosome 13
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      organelle 13017
        membrane-bounded organelle 11630
          intracellular membrane-bounded organelle 11161
            nucleus 7006
              nuclear protein-containing complex 1191
                spliceosomal complex 199
                  catalytic step 1 spliceosome 13
                    U12-type catalytic step 1 spliceosome 0
                    U2-type catalytic step 1 spliceosome 13
paths to the root