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ONTOLOGY REPORT - ANNOTATIONS

Term:U2-type catalytic step 2 spliceosome
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Accession:GO:0071007 term browser browse the term
Definition:A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.
Synonyms:exact_synonym: major catalytic step 2 spliceosome
 narrow_synonym: GT-AG catalytic step 2 spliceosome;   mammalian U2-type spliceosomal complex C;   mammalian U2-type spliceosomal complex C1;   yeast U2-type spliceosomal complex A2-2


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U2-type catalytic step 2 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqr aquarius intron-binding spliceosomal factor part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:100,874,987...100,945,044 		JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389 		JBrowse link
G Bud31 BUD31 homolog part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr12:9,462,838...9,470,387
Ensembl chr12:9,462,441...9,470,509 		JBrowse link
G Cdc40 cell division cycle 40 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr20:44,273,080...44,325,605
Ensembl chr20:44,273,089...44,325,358 		JBrowse link
G Cdc5l cell division cycle 5-like part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:28076346)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28076346 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450 		JBrowse link
G Crnkl1 crooked neck pre-mRNA splicing factor 1 part_of ISS
ISO
IBA		 GO_REF:0000024
(PMID:28076346)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:28076346 GO_REF:0000024 GO_REF:0000033 NCBI chr 3:133,338,593...133,354,329
Ensembl chr 3:133,337,039...133,354,302
Ensembl chr 6:133,337,039...133,354,302 		JBrowse link
G Cwc15 CWC15 spliceosome-associated protein part_of ISO
ISS		 (PMID:28076346)
GO_REF:0000024		 RGD
UniProt		 PMID:28076346 GO_REF:0000024 NCBI chr 8:11,305,401...11,316,326
Ensembl chr 8:11,305,424...11,316,325 		JBrowse link
G Cwc22 CWC22 spliceosome associated protein part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228 		JBrowse link
G Dhx8 DEAH-box helicase 8 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr10:86,667,641...86,704,198
Ensembl chr10:86,667,834...86,705,137 		JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 part_of ISO
IBA		 (PMID:28076346)
GO_REF:0000033		 RGD
GO_Central		 PMID:28076346 GO_REF:0000033 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079 		JBrowse link
G Plrg1 pleiotropic regulator 1 part_of ISO
ISS
IEA		 (PMID:28076346)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28076346 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522 		JBrowse link
G Ppie peptidylprolyl isomerase E part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 5:135,406,172...135,419,332
Ensembl chr 5:135,406,176...135,419,235 		JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr20:7,302,292...7,322,349
Ensembl chr20:7,302,621...7,322,354 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of ISO
IEA		 (PMID:28076346)
GO_REF:0000107		 RGD
Ensembl		 PMID:28076346 GO_REF:0000107 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606 		JBrowse link
G Rbm22 RNA binding motif protein 22 part_of ISO
IBA		 (PMID:28076346)
GO_REF:0000033		 RGD
GO_Central		 PMID:28076346 GO_REF:0000033 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569 		JBrowse link
G Snrnp40 small nuclear ribonucleoprotein U5 subunit 40 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 5:142,700,632...142,733,776
Ensembl chr 5:142,700,534...142,733,776 		JBrowse link
G Snrpa1 small nuclear ribonucleoprotein polypeptide A' part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 1:119,641,402...119,654,653
Ensembl chr 1:119,638,481...119,654,653 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of ISO
ISS		 (PMID:28076346)
GO_REF:0000024		 RGD
UniProt		 PMID:28076346 GO_REF:0000024 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812 		JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr18:1,696,838...1,707,400
Ensembl chr18:1,696,852...1,708,256 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 		JBrowse link
G Snw1 SNW domain containing 1 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 part_of ISO (PMID:28076346) RGD PMID:28076346 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751 		JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor part_of ISS
ISO		 GO_REF:0000024
(PMID:28076346)		 UniProt
RGD		 PMID:28076346 GO_REF:0000024 NCBI chr 5:147,156,492...147,164,416
Ensembl chr 5:147,156,480...147,164,414 		JBrowse link
G Xab2 XPA binding protein 2 part_of ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:28076346)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:28076346 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:1,667,672...1,679,702
Ensembl chr12:1,667,672...1,679,692 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20817
    protein-containing complex 6437
      catalytic complex 1837
        catalytic step 2 spliceosome 101
          U2-type catalytic step 2 spliceosome 30
Path 2
Term Annotations click to browse term
  cellular_component 20817
    cellular anatomical entity 20577
      organelle 14007
        membrane-bounded organelle 12604
          intracellular membrane-bounded organelle 12056
            nucleus 7484
              nuclear protein-containing complex 1305
                spliceosomal complex 222
                  U2-type spliceosomal complex 100
                    U2-type catalytic step 2 spliceosome 30
paths to the root