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ONTOLOGY REPORT - ANNOTATIONS

Term:U2-type catalytic step 1 spliceosome
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Accession:GO:0071006 term browser browse the term
Definition:A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.
Synonyms:exact_synonym: U2-type activated spliceosome;   major catalytic step 1 spliceosome
 narrow_synonym: GT-AG catalytic step 1 spliceosome;   mammalian U2-type spliceosomal complex B*;   mammalian U2-type spliceosomal complex B2;   yeast U2-type spliceosomal complex A1


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U2-type catalytic step 1 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casc3 exon junction complex subunit part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr11:98,700,634...98,724,633
Ensembl chr11:98,695,731...98,724,640 		JBrowse link
G Cwc22 CWC22 spliceosome-associated protein part_of ISO
ISS		 MGI
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 2:77,706,312...77,776,705
Ensembl chr 2:77,711,503...77,776,719 		JBrowse link
G Cwc22rt1 CWC22 spliceosome-associated protein, retrotransposed 1 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 2:83,785,949...83,789,002
Ensembl chr 2:83,786,037...83,788,529 		JBrowse link
G Cwc22rt2 CWC22 spliceosome-associated protein, retrotransposed 2 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 2:83,791,759...83,794,812
Ensembl chr 2:83,791,847...83,794,339 		JBrowse link
G Cwc22rt3 CWC22 spliceosome-associated protein, retrotransposed 3 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:83,797,569...83,800,622
Ensembl chr 2:83,797,657...83,800,149 		JBrowse link
G Cwc22rt4 CWC22 spliceosome-associated protein, retrotransposed 4 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 2:83,803,379...83,806,432
Ensembl chr 2:83,803,467...83,805,959 		JBrowse link
G Cwc22rt5 CWC22 spliceosome-associated protein, retrotransposed 5 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:83,809,189...83,812,242
Ensembl chr 2:83,809,277...83,811,769 		JBrowse link
G Cwc22rt6 CWC22 spliceosome-associated protein, retrotransposed 6 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 2:83,820,809...83,823,862
Ensembl chr 2:83,820,897...83,823,389 		JBrowse link
G Cwc22rt7 CWC22 spliceosome-associated protein, retrotransposed 7 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:83,814,999...83,818,052
Ensembl chr 2:83,815,087...83,817,579 		JBrowse link
G Cwc25 CWC25 spliceosome-associated protein part_of ISO
ISS		 MGI
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr11:97,636,296...97,657,439
Ensembl chr11:97,636,307...97,657,382 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr11:119,179,189...119,190,869
Ensembl chr11:119,179,189...119,190,915 		JBrowse link
G Eif4a3l1 eukaryotic translation initiation factor 4A3 like 1 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 6:136,304,537...136,306,981
Ensembl chr 6:136,304,537...136,306,981 		JBrowse link
G Eif4a3l2 eukaryotic translation initiation factor 4A3 like 2 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 6:116,527,132...116,529,563
Ensembl chr 6:116,528,102...116,529,463 		JBrowse link
G Isy1 ISY1 splicing factor homolog part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 6:87,795,429...87,815,723
Ensembl chr 6:87,791,251...87,815,780 		JBrowse link
G Magohb mago homolog B, exon junction complex core component part_of ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 6:131,261,351...131,270,207
Ensembl chr 6:131,261,351...131,270,207 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of IBA GO_Central GO_REF:0000033 NCBI chr19:10,872,595...10,886,923
Ensembl chr19:10,872,595...10,886,923 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr11:75,377,603...75,400,273
Ensembl chr11:75,377,642...75,400,275 		JBrowse link
G Rbm22 RNA binding motif protein 22 part_of IBA GO_Central GO_REF:0000033 NCBI chr18:60,693,858...60,705,801
Ensembl chr18:60,693,808...60,705,882 		JBrowse link
G Rbm8a RNA binding motif protein 8a part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:96,537,244...96,541,107
Ensembl chr 3:96,537,249...96,541,107 		JBrowse link
G Rbm8a2 RNA binding motif protein 8A2 part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 1:175,805,784...175,806,509
Ensembl chr 1:175,805,343...175,806,680 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein 200 (U5) part_of ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 2:127,050,306...127,082,373
Ensembl chr 2:127,050,306...127,082,371 		JBrowse link
G Tex16 testis expressed gene 16 part_of IBA GO_Central GO_REF:0000033 NCBI chr  X:110,804,655...111,159,053
Ensembl chr  X:111,148,746...111,153,549
Ensembl chr  X:111,148,746...111,153,549
Ensembl chr  X:111,148,746...111,153,549 		JBrowse link
G Yju2 YJU2 splicing factor part_of ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:56,266,187...56,274,951
Ensembl chr17:56,266,099...56,275,285 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28621
    protein-containing complex 6105
      catalytic complex 1846
        catalytic step 1 spliceosome 23
          U2-type catalytic step 1 spliceosome 23
Path 2
Term Annotations click to browse term
  cellular_component 28621
    cellular anatomical entity 19715
      organelle 13702
        membrane-bounded organelle 12704
          intracellular membrane-bounded organelle 12151
            nucleus 7540
              nuclear protein-containing complex 1291
                spliceosomal complex 234
                  U2-type spliceosomal complex 115
                    U2-type catalytic step 1 spliceosome 23
paths to the root