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ONTOLOGY REPORT - ANNOTATIONS

Term:U2-type catalytic step 1 spliceosome
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Accession:GO:0071006 term browser browse the term
Definition:A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.
Synonyms:exact_synonym: U2-type activated spliceosome;   major catalytic step 1 spliceosome
 narrow_synonym: GT-AG catalytic step 1 spliceosome;   mammalian U2-type spliceosomal complex B*;   mammalian U2-type spliceosomal complex B2;   yeast U2-type spliceosomal complex A1


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U2-type catalytic step 1 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASC3 CASC3 exon junction complex subunit part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr17:40,140,537...40,172,171
Ensembl chr17:40,140,318...40,172,171 		JBrowse link
G CWC22 CWC22 spliceosome associated protein homolog part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr 2:179,944,876...180,007,297
Ensembl chr 2:179,944,876...180,007,297 		JBrowse link
G CWC25 CWC25 spliceosome associated protein homolog part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr17:38,800,441...38,825,321
Ensembl chr17:38,800,441...38,825,355 		JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr17:80,134,369...80,147,128
Ensembl chr17:80,134,369...80,147,151 		JBrowse link
G ISY1 ISY1 splicing factor homolog part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr 3:129,127,415...129,161,063
Ensembl chr 3:129,127,415...129,161,063 		JBrowse link
G ISY1-RAB43 ISY1-RAB43 readthrough part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr 3:129,087,572...129,161,063
Ensembl chr 3:129,087,575...129,161,036 		JBrowse link
G MAGOHB mago homolog B, exon junction complex subunit part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr12:10,599,524...10,613,609
Ensembl chr12:10,604,193...10,613,609 		JBrowse link
G PRPF19 pre-mRNA processing factor 19 part_of IBA GO_Central GO_REF:0000033 NCBI chr11:60,890,547...60,906,585
Ensembl chr11:60,890,547...60,906,585 		JBrowse link
G PRPF8 pre-mRNA processing factor 8 part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr17:1,650,629...1,684,867
Ensembl chr17:1,650,629...1,684,867 		JBrowse link
G RBM22 RNA binding motif protein 22 part_of IBA GO_Central GO_REF:0000033 NCBI chr 5:150,690,792...150,701,062
Ensembl chr 5:150,690,792...150,701,077 		JBrowse link
G RBM8A RNA binding motif protein 8A part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr 1:145,921,556...145,927,484
Ensembl chr 1:145,921,556...145,927,678 		JBrowse link
G SNRNP200 small nuclear ribonucleoprotein U5 subunit 200 part_of IDA (PMID:29301961) UniProt PMID:29301961 NCBI chr 2:96,274,338...96,305,546
Ensembl chr 2:96,274,338...96,321,271 		JBrowse link
G YJU2 YJU2 splicing factor homolog part_of IDA
IEA
IBA		 (PMID:29301961) UniProt
GO_Central		 PMID:29301961 GO_REF:0000033 GO_REF:0000104 NCBI chr19:4,247,080...4,269,088
Ensembl chr19:4,247,080...4,269,088 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20785
    protein-containing complex 6759
      catalytic complex 1859
        catalytic step 1 spliceosome 13
          U2-type catalytic step 1 spliceosome 13
Path 2
Term Annotations click to browse term
  cellular_component 20785
    cellular anatomical structure 20400
      organelle 15615
        membrane-bounded organelle 14687
          intracellular membrane-bounded organelle 13466
            nucleus 8646
              nuclear protein-containing complex 1403
                spliceosomal complex 214
                  U2-type spliceosomal complex 97
                    U2-type catalytic step 1 spliceosome 13
paths to the root