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ONTOLOGY REPORT - ANNOTATIONS

Term:U2-type catalytic step 1 spliceosome
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Accession:GO:0071006 term browser browse the term
Definition:A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.
Synonyms:exact_synonym: U2-type activated spliceosome;   major catalytic step 1 spliceosome
 narrow_synonym: GT-AG catalytic step 1 spliceosome;   mammalian U2-type spliceosomal complex B*;   mammalian U2-type spliceosomal complex B2;   yeast U2-type spliceosomal complex A1

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U2-type catalytic step 1 spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casc3 CASC3 exon junction complex subunit part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955451:14,784,915...14,804,191
Ensembl chrNW_004955451:14,784,915...14,806,773 		JBrowse link
G Cwc22 CWC22 spliceosome associated protein homolog part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955403:17,070,588...17,125,918
Ensembl chrNW_004955403:17,083,414...17,125,982 		JBrowse link
G Cwc25 CWC25 spliceosome associated protein homolog part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955451:13,867,570...13,884,433
Ensembl chrNW_004955451:13,868,845...13,884,267 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955506:2,749,534...2,760,873
Ensembl chrNW_004955506:2,749,534...2,760,873 		JBrowse link
G Isy1 ISY1 splicing factor homolog part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955429:13,513,191...13,527,516
Ensembl chrNW_004955429:13,511,914...13,527,516 		JBrowse link
G Magohb mago homolog B, exon junction complex subunit part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955413:7,195,078...7,201,659
Ensembl chrNW_004955413:7,194,798...7,201,969 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955481:1,499,634...1,530,670
Ensembl chrNW_004955481:1,499,634...1,530,670 		JBrowse link
G Rbm8a RNA binding motif protein 8A part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955568:164,050...166,162
Ensembl chrNW_004955568:164,050...166,162 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955470:3,828,943...3,856,059
Ensembl chrNW_004955470:3,828,943...3,856,236 		JBrowse link
G Yju2 YJU2 splicing factor homolog part_of ISO (PMID:29301961) UniProt PMID:29301961 NCBI chrNW_004955495:4,591,242...4,605,403
Ensembl chrNW_004955495:4,592,523...4,606,005 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12732
    protein-containing complex 4263
      catalytic complex 1343
        catalytic step 1 spliceosome 10
          U2-type catalytic step 1 spliceosome 10
Path 2
Term Annotations click to browse term
  cellular_component 12732
    cellular anatomical entity 12574
      organelle 10002
        membrane-bounded organelle 9135
          intracellular membrane-bounded organelle 8689
            nucleus 5251
              nuclear protein-containing complex 978
                spliceosomal complex 141
                  U2-type spliceosomal complex 80
                    U2-type catalytic step 1 spliceosome 10
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