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ONTOLOGY REPORT - ANNOTATIONS


Term:demethylation
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Accession:GO:0070988 term browser browse the term
Definition:The process of removing one or more methyl groups from a molecule.



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demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh4 alkB homolog 4, lysine demethylase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:20,524,030...20,529,947
Ensembl chr12:20,524,030...20,529,947
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
JBrowse link
G Kdm3a lysine demethylase 3A involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kdm3b lysine demethylase 3B involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr18:26,380,859...26,436,701
Ensembl chr18:26,380,964...26,436,628
JBrowse link
G Mmachc metabolism of cobalamin associated C involved_in ISO (PMID:19801555) RGD PMID:19801555 NCBI chr 5:130,166,056...130,172,735
Ensembl chr 5:130,166,451...130,172,601
JBrowse link
G Por cytochrome p450 oxidoreductase IDA positive regulation of N-demethylation by cytochrome P450 2B4 RGD PMID:19171935 RGD:4889812 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390
JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:12,564,955...12,578,461
Ensembl chr 9:12,564,920...12,578,458
JBrowse link
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922
JBrowse link
G Eomes eomesodermin involved_in ISO (PMID:30186101) RGD PMID:30186101 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Pax6 paired box 6 involved_in IEA
ISO
GO_REF:0000107
(PMID:30186101)
Ensembl
RGD
PMID:30186101 GO_REF:0000107 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:4129024 (PMID:20639862), (PMID:21295276), (PMID:24291790)
GO_Central
RGD
PMID:20639862 PMID:21295276 PMID:24291790 GO_REF:0000033 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:20639862)
GO_Central
RGD
PMID:20639862 GO_REF:0000033 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
JBrowse link
G Tet3 tet methylcytosine dioxygenase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:20639862)
GO_Central
RGD
PMID:20639862 GO_REF:0000033 NCBI chr 4:115,867,412...115,964,433
Ensembl chr 4:115,871,265...115,964,193
JBrowse link
negative regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07015759.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Dppa3 developmental pluripotency-associated 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:155,851,461...155,854,845
Ensembl chr 4:155,815,296...155,854,861
Ensembl chr 5:155,815,296...155,854,861
JBrowse link
G Dppa3l1 developmental pluripotency associated 3-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:56,421,609...56,422,277
Ensembl chr 8:56,421,825...56,422,277
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:15087456) RGD PMID:15087456 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G LOC120096627 developmental pluripotency-associated protein 3-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:69,456,777...69,460,079
Ensembl chr14:69,457,383...69,457,859
JBrowse link
G LOC120096971 developmental pluripotency-associated protein 3-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:27,224,329...27,232,700
Ensembl chr15:27,225,434...27,225,910
JBrowse link
G Trim28 tripartite motif-containing 28 acts_upstream_of_or_within ISO MGI:1928907 (PMID:22442485) RGD PMID:22442485 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
oxidative demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IEA
(PMID:18619574)
GO_REF:0000107
RGD
Ensembl
PMID:18619574 GO_REF:0000107 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:18619574) RGD PMID:18619574
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO
IMP
(PMID:15039299), (PMID:19438707) RGD PMID:15039299 PMID:19438707 PMID:19059219 RGD:401901280 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in IDA
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000118
(PMID:15039299), (PMID:18619574)
GO_Central
TreeGrafter
RGD
PMID:15039299 PMID:18619574 PMID:12971802 GO_REF:0000033 GO_REF:0000118, RGD:5129544 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 involved_in IDA
IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
RGD
PMID:12971802 GO_REF:0000033 GO_REF:0000118, RGD:5129544 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
JBrowse link
G Cyp3a73 cytochrome P450, family 3, subfamily a, polypeptide 73 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr12:8,955,593...8,995,061
Ensembl chr12:8,956,457...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO
IBA
IEA
(PMID:15039299)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:15039299 GO_REF:0000033 GO_REF:0000118 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G ENSRNOG00000062654 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr12:9,126,978...9,150,971 JBrowse link
G ENSRNOG00000063231 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr12:9,015,420...9,025,660 JBrowse link
oxidative RNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO
IBA
(PMID:31188562)
GO_REF:0000033
RGD
GO_Central
PMID:31188562 GO_REF:0000033 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24360279)
UniProt
Ensembl
RGD
PMID:24360279 GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
positive regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stpg1 sperm-tail PG-rich repeat containing 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:147,717,084...147,769,792
Ensembl chr 5:147,726,646...147,769,788
JBrowse link
G Stpg4 sperm-tail PG-rich repeat containing 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:7,108,827...7,158,519
Ensembl chr 6:7,108,869...7,151,390
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      demethylation 37
        DNA demethylation + 18
        oxidative demethylation + 13
        protein demethylation + 0
paths to the root