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ONTOLOGY REPORT - ANNOTATIONS


Term:CRD-mediated mRNA stability complex
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Accession:GO:0070937 term browser browse the term
Definition:A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.
Comment:See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'.
Synonyms:exact_synonym: coding-region determinant of instability-mediated mRNA stability complex;   coding-region instability determinant -mediated mRNA stability complex



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CRD-mediated mRNA stability complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csde1 cold shock domain containing E1 part_of ISO (PMID:15314026) RGD PMID:15314026 NCBI chr 2:190,546,015...190,582,790
Ensembl chr 2:190,554,980...190,582,784
JBrowse link
G Dhx9 DExH-box helicase 9 part_of ISO (PMID:19029303) RGD PMID:19029303 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U part_of IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:19029303)
Ensembl
RGD
PMID:19029303 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 part_of ISO
ISS
(PMID:19029303)
GO_REF:0000024
RGD
UniProt
PMID:19029303 GO_REF:0000024 NCBI chr10:80,908,300...80,951,097
Ensembl chr10:80,908,076...80,951,129
JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein part_of ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19029303)
UniProt
RGD
PMID:19029303 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515
JBrowse link
G Ybx1 Y box binding protein 1 part_of ISO (PMID:19029303) RGD PMID:19029303 NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      CRD-mediated mRNA stability complex 6
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      intracellular anatomical structure 14287
        cytoplasm 11289
          CRD-mediated mRNA stability complex 6
paths to the root