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ONTOLOGY REPORT - ANNOTATIONS


Term:inclusion body assembly
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Accession:GO:0070841 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inclusion body.


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inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101976627 prosaposin acts_upstream_of_or_within ISO (MGI:3664385|PMID:9678511) MGI PMID:9678511 MGI:3664385 NCBI chrNW_004936521:6,975,844...7,009,460 JBrowse link
aggresome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlgap1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chrNW_004936672:610,020...1,094,718 JBrowse link
G Hdac6 histone deacetylase 6 involved_in
acts_upstream_of_or_within
ISO (PMID:14675537)
(MGI:3653156|PMID:16810319)
BHF-UCL
MGI
PMID:14675537 PMID:16810319 MGI:3653156 NCBI chrNW_004936721:757,500...778,416 JBrowse link
G LOC101972576 valosin containing protein acts_upstream_of_or_within ISO (MGI:3653156|PMID:16810319) MGI PMID:16810319 MGI:3653156 NCBI chrNW_004936524:3,085,959...3,102,461 JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (MGI:3574149|PMID:15748170) MGI PMID:15748170 MGI:3574149 NCBI chrNW_004936724:1,747,015...1,780,298 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:14645198) BHF-UCL PMID:14645198 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Trim37 tripartite motif containing 37 involved_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chrNW_004936490:4,163,871...4,310,016 JBrowse link
G Ubd ubiquitin D involved_in ISO (PMID:19033385) UniProt PMID:19033385 NCBI chrNW_004936723:1,218,621...1,221,070 JBrowse link
negative regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004936471:36,724,689...36,741,029 JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004936659:3,039,304...3,051,373 JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:20889486)
(PMID:15936278), (PMID:21231916)
ParkinsonsUK-UCL
BHF-UCL
PMID:15936278 PMID:20889486 PMID:21231916 NCBI chrNW_004936569:1,689,926...1,697,179 JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 involved_in ISO (PMID:21231916)
(PMID:20889486)
UniProt
ParkinsonsUK-UCL
PMID:20889486 PMID:21231916 NCBI chrNW_004936797:332,962...377,397 JBrowse link
G Dnajb8 DnaJ heat shock protein family (Hsp40) member B8 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004936798:425,156...425,916 JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004936495:8,243,369...8,246,082 JBrowse link
G LOC101955831 heat shock 70 kDa protein 1 involved_in ISO (PMID:15603737), (PMID:21231916) BHF-UCL PMID:15603737 PMID:21231916 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 involved_in ISO (PMID:15603737), (PMID:21231916) BHF-UCL PMID:15603737 PMID:21231916 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Sacs sacsin molecular chaperone involved_in ISO (PMID:19208651) BHF-UCL PMID:19208651 NCBI chrNW_004936688:1,987,075...2,079,148 JBrowse link
negative regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sorl1 sortilin related receptor 1 involved_in ISO (MGI:5569468|PMID:22986780) Alzheimers_University_of_Toronto PMID:22986780 MGI:5569468 NCBI chrNW_004936542:6,192,407...6,352,835 JBrowse link
positive regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme ISO RGD PMID:12401444 RGD:2316159 NCBI chrNW_004936588:160,066...167,259 JBrowse link
G Hap1 huntingtin associated protein 1 involved_in ISO PMID:9798945 UniProt PMID:9798945 RGD:10047369 NCBI chrNW_004936490:16,645,116...16,652,310 JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004936541:4,470,210...4,475,233 JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004936697:2,122,727...2,143,988 JBrowse link
positive regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24154541) Alzheimers_University_of_Toronto PMID:24154541 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Clu clusterin involved_in ISO (PMID:15897157) Alzheimers_University_of_Toronto PMID:15897157 NCBI chrNW_004936675:499,745...513,515 JBrowse link
regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:15603737) BHF-UCL PMID:15603737 RGD:8553807 NCBI chrNW_004936621:1,573,237...1,578,257 JBrowse link
G LOC101967683 synuclein alpha interacting protein involved_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chrNW_004936575:2,727,253...2,873,428 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 12295
    cellular process 11513
      cellular component organization or biogenesis 4977
        cellular component biogenesis 2470
          cellular component assembly 2355
            inclusion body assembly 27
              Lewy body formation + 0
              aggresome assembly 7
              negative regulation of inclusion body assembly + 11
              neurofibrillary tangle assembly + 3
              positive regulation of inclusion body assembly + 7
              regulation of inclusion body assembly + 19
paths to the root