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ONTOLOGY REPORT - ANNOTATIONS


Term:inclusion body assembly
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Accession:GO:0070841 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inclusion body.



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inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PSAP prosaposin acts_upstream_of_or_within ISO (MGI:3664385|PMID:9678511) MGI PMID:9678511 MGI:3664385 NCBI chr 4:22,571,095...22,603,880
Ensembl chr 4:22,572,153...22,603,848
JBrowse link
aggresome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLGAP1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 7:70,082,563...70,949,116
Ensembl chr 7:70,081,885...70,406,213
JBrowse link
G HDAC6 histone deacetylase 6 acts_upstream_of_or_within
involved_in
ISO (MGI:3653156|PMID:16810319)
(PMID:14675537)
MGI
BHF-UCL
PMID:14675537 PMID:16810319 MGI:3653156 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (MGI:3574149|PMID:15748170) MGI PMID:15748170 MGI:3574149 NCBI chr 5:38,806,731...38,839,002
Ensembl chr 5:38,807,826...38,838,971
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:14645198) BHF-UCL PMID:14645198 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G TRIM37 tripartite motif containing 37 involved_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chr 9:33,446,903...33,687,650
Ensembl chr 9:33,446,918...33,687,555
JBrowse link
G UBD ubiquitin D involved_in ISO (PMID:19033385) UniProt PMID:19033385 NCBI chr35:26,426,919...26,436,189 JBrowse link
G VCP valosin containing protein acts_upstream_of_or_within ISO (MGI:3653156|PMID:16810319) MGI PMID:16810319 MGI:3653156 NCBI chr11:51,636,986...51,651,749
Ensembl chr11:51,637,411...51,651,714
JBrowse link
negative regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chr 3:58,390,379...58,402,497
Ensembl chr 3:58,342,874...58,401,276
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,120,604...48,131,091
Ensembl chr20:48,121,379...48,130,060
JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278), (PMID:21231916)
(PMID:20889486)
BHF-UCL
ParkinsonsUK-UCL
PMID:15936278 PMID:20889486 PMID:21231916 NCBI chr37:25,826,496...25,834,011
Ensembl chr37:25,827,713...25,833,144
JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 involved_in ISO (PMID:20889486)
(PMID:21231916)
ParkinsonsUK-UCL
UniProt
PMID:20889486 PMID:21231916 NCBI chr16:19,792,957...19,849,299
Ensembl chr16:19,768,639...19,848,139
JBrowse link
G DNAJB8 DnaJ heat shock protein family (Hsp40) member B8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:2,453,100...2,454,152
Ensembl chr20:2,453,297...2,453,650
JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252
JBrowse link
G HSP70 heat shock protein 70 involved_in ISO (PMID:15603737), (PMID:21231916) BHF-UCL PMID:15603737 PMID:21231916 NCBI chr12:1,285,282...1,287,670 JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:38,967,104...38,969,806
Ensembl chr 8:38,967,400...38,969,313
JBrowse link
G SACS sacsin molecular chaperone involved_in ISO (PMID:19208651) BHF-UCL PMID:19208651 NCBI chr25:15,207,959...15,297,483
Ensembl chr25:15,207,839...15,296,078
JBrowse link
negative regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORL1 sortilin related receptor 1 involved_in ISO (MGI:5569468|PMID:22986780) Alzheimers_University_of_Toronto PMID:22986780 MGI:5569468 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784
JBrowse link
positive regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme ISO RGD PMID:12401444 RGD:2316159 NCBI chr20:57,960,506...57,967,388
Ensembl chr20:57,960,833...57,967,371
JBrowse link
G HAP1 huntingtin associated protein 1 involved_in ISO PMID:9798945 UniProt PMID:9798945 RGD:10047369 NCBI chr 9:21,065,770...21,074,462
Ensembl chr 9:21,065,846...21,072,991
JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252
JBrowse link
G LOC100687259 26S proteasome regulatory subunit 10B ISO RGD PMID:18986984 RGD:7242199 NCBI chr32:35,814,756...35,816,311 JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 ISO RGD PMID:18986984 RGD:7242199 NCBI chr 9:11,783,422...11,787,624
Ensembl chr 9:11,783,466...11,787,617
JBrowse link
positive regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO (PMID:24154541) Alzheimers_University_of_Toronto PMID:24154541 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G CLU clusterin involved_in ISO (PMID:15897157) Alzheimers_University_of_Toronto PMID:15897157 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563
JBrowse link
regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in ISO PMID:15603737
(PMID:15603737)
BHF-UCL PMID:15603737 RGD:8553807 NCBI chr 8:71,318,730...71,324,743
Ensembl chr 8:71,321,625...71,322,992
JBrowse link
G SNCAIP synuclein alpha interacting protein involved_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chr11:12,226,940...12,375,725
Ensembl chr11:12,301,719...12,375,560
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13969
    cellular process 13228
      cellular component organization or biogenesis 5515
        cellular component biogenesis 2768
          cellular component assembly 2600
            inclusion body assembly 26
              Lewy body formation + 0
              aggresome assembly 7
              negative regulation of inclusion body assembly + 10
              neurofibrillary tangle assembly + 3
              positive regulation of inclusion body assembly + 7
              regulation of inclusion body assembly + 18
paths to the root