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ONTOLOGY REPORT - ANNOTATIONS

Term:inclusion body assembly
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Accession:GO:0070841 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inclusion body.

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inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (PMID:27654426) MGI PMID:27654426 NCBI chrNW_004955428:13,519,285...13,548,007
Ensembl chrNW_004955428:13,519,277...13,544,695 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:9678511) MGI PMID:9678511 NCBI chrNW_004955437:19,667,252...19,683,669 JBrowse link
aggresome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlgap1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chrNW_004955402:6,809,126...7,105,356
Ensembl chrNW_004955402:6,451,864...7,105,411 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:14675537)
(PMID:16810319)		 BHF-UCL
MGI		 PMID:14675537 PMID:16810319 NCBI chrNW_004955543:348,314...378,391
Ensembl chrNW_004955543:348,019...378,071 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (PMID:15748170) MGI PMID:15748170 NCBI chrNW_004955467:2,422,181...2,456,925
Ensembl chrNW_004955467:2,423,659...2,457,307 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:14645198) BHF-UCL PMID:14645198 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
G Trim37 tripartite motif containing 37 involved_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chrNW_004955451:3,839,757...4,014,178
Ensembl chrNW_004955451:3,878,416...3,989,208 		JBrowse link
G Ubd ubiquitin D involved_in ISO (PMID:19033385) UniProt PMID:19033385 NCBI chrNW_004955583:29,438...29,873
Ensembl chrNW_004955583:29,438...31,555 		JBrowse link
G Vcp valosin containing protein acts_upstream_of_or_within ISO (PMID:16810319) MGI PMID:16810319 NCBI chrNW_004955472:1,111,649...1,124,076
Ensembl chrNW_004955472:1,107,164...1,124,076 		JBrowse link
negative regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004955450:757,485...771,033
Ensembl chrNW_004955450:757,485...771,033 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004955415:33,098,503...33,102,125
Ensembl chrNW_004955415:33,098,210...33,103,143 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278), (PMID:21231916)
(PMID:20889486)		 BHF-UCL
ParkinsonsUK-UCL		 PMID:15936278 PMID:20889486 PMID:21231916 NCBI chrNW_004955453:14,147,286...14,154,396
Ensembl chrNW_004955453:14,148,070...14,154,670 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 involved_in ISO (PMID:20889486)
(PMID:21231916)		 ParkinsonsUK-UCL
UniProt		 PMID:20889486 PMID:21231916 NCBI chrNW_004955579:240,058...298,592
Ensembl chrNW_004955579:240,058...298,592 		JBrowse link
G Dnajb8 DnaJ heat shock protein family (Hsp40) member B8 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004955429:15,349,346...15,350,343
Ensembl chrNW_004955429:15,349,564...15,350,268 		JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chrNW_004955466:5,344,366...5,347,707
Ensembl chrNW_004955466:5,344,366...5,347,707 		JBrowse link
G Sacs sacsin molecular chaperone involved_in ISO (PMID:19208651) BHF-UCL PMID:19208651 NCBI chrNW_004955497:3,701,515...3,752,627
Ensembl chrNW_004955497:3,706,882...3,754,663 		JBrowse link
negative regulation of Lewy body formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnb1 interferon beta 1 involved_in ISO (MGI:5695780|PMID:26451483) UniProt PMID:26451483 MGI:5695780 NCBI chrNW_004955434:23,301,623...23,302,304 JBrowse link
negative regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sorl1 sortilin related receptor 1 involved_in ISO (MGI:5569468|PMID:22986780) Alzheimers_University_of_Toronto PMID:22986780 MGI:5569468 NCBI chrNW_004955412:22,421,984...22,576,179
Ensembl chrNW_004955412:22,421,984...22,576,179 		JBrowse link
positive regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme ISO RGD PMID:12401444 RGD:2316159 NCBI chrNW_004955495:7,170,419...7,178,093
Ensembl chrNW_004955495:7,170,419...7,178,093 		JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351 		JBrowse link
G Nox1 NADPH oxidase 1 ISO RGD PMID:23077033 RGD:329961565 NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004955478:7,996,902...8,002,183
Ensembl chrNW_004955478:7,996,902...8,002,183 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 ISO RGD PMID:18986984 RGD:7242199 NCBI chrNW_004955409:10,454,210...10,474,872
Ensembl chrNW_004955409:10,452,615...10,475,100 		JBrowse link
positive regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24154541) Alzheimers_University_of_Toronto PMID:24154541 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888 		JBrowse link
G Clu clusterin involved_in ISO (PMID:15897157) Alzheimers_University_of_Toronto PMID:15897157 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876 		JBrowse link
regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:15603737) BHF-UCL PMID:15603737 RGD:8553807 NCBI chrNW_004955538:2,412,297...2,416,094
Ensembl chrNW_004955538:2,412,297...2,415,132 		JBrowse link
G Sncaip synuclein alpha interacting protein involved_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chrNW_004955521:410,270...548,691
Ensembl chrNW_004955521:482,433...548,751 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    cellular process 11505
      cellular component organization or biogenesis 5341
        cellular component biogenesis 2613
          cellular component assembly 2439
            inclusion body assembly 27
              Lewy body formation + 1
              aggresome assembly 7
              negative regulation of inclusion body assembly + 10
              neurofibrillary tangle assembly + 3
              positive regulation of inclusion body assembly + 7
              regulation of inclusion body assembly + 18
paths to the root