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ONTOLOGY REPORT - ANNOTATIONS


Term:inclusion body assembly
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Accession:GO:0070841 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inclusion body.



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inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PSAP prosaposin acts_upstream_of_or_within ISO (MGI:3664385|PMID:9678511) MGI PMID:9678511 MGI:3664385 NCBI chr10:68,286,359...68,321,349
Ensembl chr10:70,810,881...70,828,781
JBrowse link
aggresome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLGAP1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr18:9,816,171...10,781,490
Ensembl chr18:12,704,306...13,091,118
JBrowse link
G HDAC6 histone deacetylase 6 involved_in
acts_upstream_of_or_within
ISO (PMID:14675537)
(MGI:3653156|PMID:16810319)
BHF-UCL
MGI
PMID:14675537 PMID:16810319 MGI:3653156 NCBI chr  X:41,099,539...41,122,650
Ensembl chr  X:48,960,430...48,982,642
JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (MGI:3574149|PMID:15748170) MGI PMID:15748170 MGI:3574149 NCBI chr17:36,389,549...36,425,161
Ensembl chr17:41,038,302...41,073,872
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:14645198) BHF-UCL PMID:14645198 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G TRIM37 tripartite motif containing 37 involved_in ISO (PMID:15885686) UniProt PMID:15885686 NCBI chr17:53,070,235...53,178,209
Ensembl chr17:57,904,813...58,027,100
JBrowse link
G UBD ubiquitin D involved_in ISO (PMID:19033385) UniProt PMID:19033385 NCBI chr 6:29,359,680...29,364,014
Ensembl chr 6:30,018,444...30,022,814
JBrowse link
G VCP valosin containing protein acts_upstream_of_or_within ISO (MGI:3653156|PMID:16810319) MGI PMID:16810319 MGI:3653156 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588
JBrowse link
negative regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chr15:57,193,545...57,211,518
Ensembl chr15:76,158,155...76,176,089
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chr19:14,078,201...14,081,884
Ensembl chr19:14,922,389...14,926,268
JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:20889486)
(PMID:15936278), (PMID:21231916)
ParkinsonsUK-UCL
BHF-UCL
PMID:15936278 PMID:20889486 PMID:21231916 NCBI chr2B:106,536,846...106,544,430
Ensembl chr2B:225,127,967...225,135,556
JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 involved_in ISO (PMID:20889486)
(PMID:21231916)
ParkinsonsUK-UCL
UniProt
PMID:20889486 PMID:21231916 NCBI chr 7:148,952,823...149,034,578
Ensembl chr 7:160,646,321...160,726,447
JBrowse link
G DNAJB8 DnaJ heat shock protein family (Hsp40) member B8 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chr 3:125,509,528...125,514,393
Ensembl chr 3:132,873,880...132,874,578
JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:15603737), (PMID:21231916) BHF-UCL PMID:15603737 PMID:21231916 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chr14:45,124,326...45,127,105
Ensembl chr14:63,373,840...63,375,762
JBrowse link
G SACS sacsin molecular chaperone involved_in ISO (PMID:19208651) BHF-UCL PMID:19208651 NCBI chr13:4,642,078...4,745,453
Ensembl chr13:22,937,320...22,982,553
JBrowse link
negative regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORL1 sortilin related receptor 1 involved_in ISO (MGI:5569468|PMID:22986780) Alzheimers_University_of_Toronto PMID:22986780 MGI:5569468 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432
JBrowse link
positive regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme ISO RGD PMID:12401444 RGD:2316159 NCBI chr19:592,856...602,811
Ensembl chr19:502,766...512,173
JBrowse link
G HAP1 huntingtin associated protein 1 involved_in ISO PMID:9798945 UniProt PMID:9798945 RGD:10047369 NCBI chr17:15,578,658...15,596,313
Ensembl chr17:15,797,949...15,810,299
JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:22216146 RGD:10402367 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 ISO RGD PMID:18986984 RGD:7242199 NCBI chr17:57,906,934...57,911,551
Ensembl chr17:63,051,050...63,055,907
JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 ISO RGD PMID:18986984 RGD:7242199 NCBI chr14:33,303,689...33,324,502
Ensembl chr14:51,587,467...51,608,044
JBrowse link
positive regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO (PMID:24154541) Alzheimers_University_of_Toronto PMID:24154541 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G CLU clusterin involved_in ISO (PMID:15897157) Alzheimers_University_of_Toronto PMID:15897157 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523
JBrowse link
regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in ISO (PMID:15603737) BHF-UCL PMID:15603737 RGD:8553807 NCBI chr14:84,182,879...84,189,180
Ensembl chr14:103,997,524...103,998,927
JBrowse link
G SNCAIP synuclein alpha interacting protein involved_in ISO (PMID:15603737) BHF-UCL PMID:15603737 NCBI chr 5:117,692,836...117,847,221
Ensembl chr 5:123,555,073...123,630,921
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12786
    cellular process 11938
      cellular component organization or biogenesis 5052
        cellular component biogenesis 2498
          cellular component assembly 2383
            inclusion body assembly 26
              Lewy body formation + 0
              aggresome assembly 7
              negative regulation of inclusion body assembly + 10
              neurofibrillary tangle assembly + 3
              positive regulation of inclusion body assembly + 7
              regulation of inclusion body assembly + 18
paths to the root