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ONTOLOGY REPORT - ANNOTATIONS

Term:inclusion body assembly
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Accession:GO:0070841 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inclusion body.


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inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epg5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_or_within ISO
IEA 		(PMID:27715390)
GO_REF:0000107 		RGD
Ensembl		 PMID:27715390 GO_REF:0000107 NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO
IEA 		(PMID:27654426)
GO_REF:0000107 		RGD
Ensembl		 PMID:27654426 GO_REF:0000107 NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:1888378 (PMID:9678511) RGD PMID:9678511 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
aggresome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlgap1 DLG associated protein 1 involved_in IMP PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:14675537)
GO_REF:0000107
MGI:99919 (PMID:16810319) 		RGD
Ensembl		 PMID:14675537 PMID:16810319 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (PMID:15748170) RGD PMID:15748170 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS 		(PMID:14645198)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
ParkinsonsUK-UCL		 PMID:14645198 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA 		(PMID:15885686)
GO_REF:0000033 		RGD
GO_Central		 PMID:15885686 GO_REF:0000033 NCBI chr10:72,440,672...72,572,831
Ensembl chr10:71,943,375...72,075,558 		JBrowse link
G Ubd ubiquitin D involved_in ISS
ISO 		GO_REF:0000024
(PMID:19033385) 		UniProt
RGD		 PMID:19033385 GO_REF:0000024 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Vcp valosin-containing protein acts_upstream_of_or_within ISO
IEA 		MGI:1333752 (PMID:16810319)
GO_REF:0000107 		RGD
Ensembl		 PMID:16810319 GO_REF:0000107 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
negative regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 involved_in ISO
IEA 		(PMID:21231916)
GO_REF:0000107 		RGD
Ensembl		 PMID:21231916 GO_REF:0000107 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO
IEA 		(PMID:15936278), (PMID:20889486)
GO_REF:0000107
(PMID:21231916) 		RGD
Ensembl		 PMID:15936278 PMID:20889486 PMID:21231916 GO_REF:0000107 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 involved_in ISO (PMID:20889486), (PMID:21231916) RGD PMID:20889486 PMID:21231916 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659 		JBrowse link
G Dnajb8 DnaJ heat shock protein family (Hsp40) member B8 involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 4:120,681,918...120,685,108
Ensembl chr 4:120,681,926...120,687,552 		JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:22216146 RGD:10402367 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:15603737), (PMID:21231916) RGD PMID:15603737 PMID:21231916 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:15603737), (PMID:21231916) RGD PMID:15603737 PMID:21231916 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 involved_in ISO
IEA 		(PMID:21231916)
GO_REF:0000107 		RGD
Ensembl		 PMID:21231916 GO_REF:0000107 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Sacs sacsin molecular chaperone involved_in ISO
IEA 		(PMID:19208651)
GO_REF:0000107 		RGD
Ensembl		 PMID:19208651 GO_REF:0000107 NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335 		JBrowse link
negative regulation of Lewy body formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnb1 interferon beta 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:26451483) 		UniProt
RGD		 PMID:26451483 GO_REF:0000024 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
negative regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir219a1 microRNA 219a-1 acts_upstream_of ISO (PMID:30556160) RGD PMID:30556160 NCBI chr20:4,829,687...4,829,796
Ensembl chr20:4,829,687...4,829,796 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO
IEA 		(PMID:22986780)
GO_REF:0000107 		RGD
Ensembl		 PMID:22986780 GO_REF:0000107 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO
IEA 		(PMID:19363271)
GO_REF:0000107 		RGD
Ensembl		 PMID:19363271 GO_REF:0000107 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
positive regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc34 cell division cycle 34, ubiquitin conjugating enzyme IMP RGD PMID:12401444 RGD:2316159 NCBI chr 7:10,668,209...10,674,206
Ensembl chr 7:10,017,588...10,023,186 		JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IDA PMID:9798945 UniProt PMID:9798945 RGD:10047369 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:22216146 RGD:10402367 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Nox1 NADPH oxidase 1 IMP RGD PMID:23077033 RGD:329961565 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 IMP RGD PMID:18986984 RGD:7242199 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 IMP RGD PMID:18986984 RGD:7242199 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
positive regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24154541) RGD PMID:24154541 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Clu clusterin involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:15897157)
GO_REF:0000024 		Ensembl
RGD
Alzheimers_University_of_Toronto		 PMID:15897157 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO
IBA
IDA 		(PMID:15603737)
GO_REF:0000033 		RGD
GO_Central		 PMID:15603737 PMID:15603737 GO_REF:0000033, RGD:8553807 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Sncaip synuclein, alpha interacting protein involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15603737) 		ParkinsonsUK-UCL
Ensembl
RGD		 PMID:15603737 GO_REF:0000024 GO_REF:0000107 NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929 		JBrowse link
regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in IEA
ISO 		GO_REF:0000107
(PMID:25556849) 		Ensembl
RGD		 PMID:25556849 GO_REF:0000107 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Map2 microtubule-associated protein 2 involved_in IDA PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mark2 microtubule affinity regulating kinase 2 involved_in IMP PMID:24251416 ARUK-UCL PMID:24251416 RGD:13602001 NCBI chr 1:204,461,029...204,526,247
Ensembl chr 1:204,461,030...204,525,652 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cellular component organization or biogenesis 7114
        cellular component biogenesis 3560
          cellular component assembly 3215
            inclusion body assembly 36
              Lewy body formation + 1
              aggresome assembly 7
              negative regulation of inclusion body assembly + 13
              neurofibrillary tangle assembly + 8
              positive regulation of inclusion body assembly + 8
              regulation of inclusion body assembly + 25
paths to the root