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ONTOLOGY REPORT - ANNOTATIONS


Term:inclusion body assembly
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Accession:GO:0070841 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inclusion body.



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inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (PMID:27654426) RGD PMID:27654426 NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971
JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:1888378 (PMID:9678511) RGD PMID:9678511 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
JBrowse link
aggresome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlgap1 DLG associated protein 1 involved_in IMP PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817
JBrowse link
G Hdac6 histone deacetylase 6 involved_in
acts_upstream_of_or_within
ISO (PMID:14675537)
MGI:99919 (PMID:16810319)
RGD PMID:14675537 PMID:16810319 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (PMID:15748170) RGD PMID:15748170 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS
(PMID:14645198)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
ParkinsonsUK-UCL
PMID:14645198 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO (PMID:15885686) RGD PMID:15885686 NCBI chr10:71,943,384...72,075,563
Ensembl chr10:71,943,375...72,075,558
JBrowse link
G Ubd ubiquitin D involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19033385)
UniProt
Ensembl
RGD
PMID:19033385 GO_REF:0000024 GO_REF:0000107 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Vcp valosin-containing protein acts_upstream_of_or_within ISO MGI:1333752 (PMID:16810319) RGD PMID:16810319 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
negative regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278), (PMID:20889486)
(PMID:21231916)
RGD PMID:15936278 PMID:20889486 PMID:21231916 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 involved_in ISO (PMID:20889486), (PMID:21231916) RGD PMID:20889486 PMID:21231916 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dnajb8 DnaJ heat shock protein family (Hsp40) member B8 involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 4:120,681,918...120,685,108
Ensembl chr 4:120,681,926...120,687,552
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:22216146 RGD:10402367 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:15603737), (PMID:21231916) RGD PMID:15603737 PMID:21231916 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:15603737), (PMID:21231916) RGD PMID:15603737 PMID:21231916 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Sacs sacsin molecular chaperone involved_in ISO (PMID:19208651) RGD PMID:19208651 NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335
JBrowse link
negative regulation of Lewy body formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnb1 interferon beta 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5695780|PMID:26451483)
UniProt
RGD
PMID:26451483 GO_REF:0000024 MGI:5695780 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
negative regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sorl1 sortilin related receptor 1 involved_in ISO (MGI:5569468|PMID:22986780) RGD PMID:22986780 MGI:5569468 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
positive regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme IMP RGD PMID:12401444 RGD:2316159 NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IDA PMID:9798945 UniProt PMID:9798945 RGD:10047369 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:22216146 RGD:10402367 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Nox1 NADPH oxidase 1 IMP RGD PMID:23077033 RGD:329961565 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 IMP RGD PMID:18986984 RGD:7242199 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 IMP RGD PMID:18986984 RGD:7242199 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
JBrowse link
positive regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24154541) RGD PMID:24154541 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Clu clusterin involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:15897157)
GO_REF:0000024
Ensembl
RGD
Alzheimers_University_of_Toronto
PMID:15897157 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
regulation of inclusion body assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO
IBA
IDA
(PMID:15603737)
GO_REF:0000033
RGD
GO_Central
PMID:15603737 PMID:15603737 GO_REF:0000033, RGD:8553807 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Sncaip synuclein, alpha interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:15603737)
ParkinsonsUK-UCL
RGD
PMID:15603737 GO_REF:0000024 NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cellular component organization or biogenesis 7217
        cellular component biogenesis 3571
          cellular component assembly 3189
            inclusion body assembly 30
              Lewy body formation + 1
              aggresome assembly 7
              negative regulation of inclusion body assembly + 12
              neurofibrillary tangle assembly + 3
              positive regulation of inclusion body assembly + 8
              regulation of inclusion body assembly + 21
paths to the root