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ONTOLOGY REPORT - ANNOTATIONS


Term:FHF complex
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Accession:GO:0070695 term browser browse the term
Definition:A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
Comment:Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.


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FHF complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07026291.1 part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr16:70,778,913...70,831,164 JBrowse link
G Aktip AKT interacting protein part_of ISS
ISO
GO_REF:0000024
(PMID:18799622), (PMID:32073997)
UniProt
RGD
PMID:18799622 PMID:32073997 GO_REF:0000024 NCBI chr19:17,290,048...17,300,054
Ensembl chr19:17,290,178...17,300,050
JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B part_of ISS
ISO
GO_REF:0000024
(PMID:18799622), (PMID:32073997)
UniProt
RGD
PMID:18799622 PMID:32073997 GO_REF:0000024 NCBI chr 1:170,216,505...170,238,898
Ensembl chr 1:170,212,817...170,238,890
JBrowse link
G Hook1 hook microtubule-tethering protein 1 part_of ISO (PMID:18799622), (PMID:32073997) RGD PMID:18799622 PMID:32073997 NCBI chr 5:114,940,053...115,000,691
Ensembl chr 5:114,940,053...115,000,691
JBrowse link
G Hook2 hook microtubule-tethering protein 2 part_of ISO (PMID:18799622), (PMID:32073997) RGD PMID:18799622 PMID:32073997 NCBI chr19:26,106,713...26,119,353
Ensembl chr19:26,106,838...26,119,352
JBrowse link
G Hook3 hook microtubule-tethering protein 3 part_of ISO (PMID:18799622), (PMID:32073997) RGD PMID:18799622 PMID:32073997 NCBI chr16:70,710,347...70,818,789 JBrowse link

Term paths to the root
Path 1
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  cellular_component 20142
    protein-containing complex 6031
      FHF complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20142
    cellular anatomical entity 19842
      intracellular anatomical structure 14431
        cytoplasm 11416
          FHF complex 6
paths to the root