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ONTOLOGY REPORT - ANNOTATIONS


Term:Grb2-Sos complex
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Accession:GO:0070618 term browser browse the term
Definition:A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
Synonyms:narrow_synonym: Grb2-mSos1 complex


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Grb2-Sos complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 IDA RGD PMID:12112020 RGD:634064 NCBI chr 5:147,927,145...147,953,093
Ensembl chr 5:147,927,152...147,953,093
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Path 1
Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      membrane protein complex 1237
        plasma membrane protein complex 558
          Grb2-Sos complex 1
Path 2
Term Annotations click to browse term
  cellular_component 20142
    cellular anatomical entity 19842
      membrane 10019
        plasma membrane 6231
          plasma membrane protein complex 558
            Grb2-Sos complex 1
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