Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
Synonyms:
exact_synonym:
down regulation of thiamine diphosphate biosynthetic process; downregulation of thiamine diphosphate biosynthetic process; negative regulation of thiamin diphosphate biosynthetic process; negative regulation of thiamine diphosphate anabolism; negative regulation of thiamine diphosphate biosynthesis; negative regulation of thiamine diphosphate formation; negative regulation of thiamine diphosphate synthesis
narrow_synonym:
inhibition of thiamine diphosphate biosynthetic process