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ONTOLOGY REPORT - ANNOTATIONS


Term:protein kinase C signaling
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Accession:GO:0070528 term browser browse the term
Definition:A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
Synonyms:exact_synonym: PKC signal transduction;   protein kinase C signal transduction
 related_synonym: PKC signaling cascade;   protein kinase C signaling cascade;   protein kinase C signalling cascade



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protein kinase C signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrg1 adhesion G protein-coupled receptor G1 involved_in ISO
IEA
ISS
(PMID:21724588)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21724588 GO_REF:0000024 GO_REF:0000107 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 involved_in ISO (MGI:5609214|PMID:25313067) RGD PMID:25313067 MGI:5609214 NCBI chr15:24,398,383...24,415,837
Ensembl chr15:24,398,419...24,398,922
JBrowse link
G Ankrd1 ankyrin repeat domain 1 acts_upstream_of_or_within ISO MGI:1330824 (MGI:5882279|PMID:27353086) RGD PMID:27353086 MGI:5882279 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IDA RGD PMID:16027158 RGD:11534986 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Avp arginine vasopressin involved_in ISO (PMID:18402937) RGD PMID:18402937 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Coro1b coronin 1B IDA RGD PMID:16027158 RGD:11534986 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1097717 (MGI:5882279|PMID:27353086)
Ensembl
RGD
PMID:27353086 GO_REF:0000107 MGI:5882279 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:15632189) RGD PMID:15632189 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
JBrowse link
G Fibin fin bud initiation factor homolog acts_upstream_of_or_within ISO (PMID:21615908) RGD PMID:21615908 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
JBrowse link
G Flot1 flotillin 1 involved_in ISO
IBA
(PMID:21399631)
(MGI:5634885|PMID:21399631)
PMID:21873635
RGD PMID:21399631 PMID:21873635 MGI:5634885, RGD:13792537 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20099302)
UniProt
Ensembl
RGD
PMID:20099302 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor involved_in ISO (PMID:16611642) RGD PMID:16611642 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
ISO
GO_REF:0000107
(PMID:24008408)
Ensembl
RGD
PMID:24008408 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Plek pleckstrin involved_in ISO
IEA
(MGI:3844782|PMID:19190246)
GO_REF:0000107
RGD
Ensembl
PMID:19190246 GO_REF:0000107 MGI:3844782 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Plvap plasmalemma vesicle associated protein NOT|involved_in ISO (PMID:15155804) RGD PMID:15155804 NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301
JBrowse link
G Prkch protein kinase C, eta IMP RGD PMID:9677361 RGD:5131657 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prkcz protein kinase C, zeta IMP RGD PMID:20570724 RGD:5131661 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Prss33 serine protease 33 involved_in ISO (PMID:12795636) RGD PMID:12795636 NCBI chr10:12,858,941...12,861,281
Ensembl chr10:12,858,941...12,861,281
JBrowse link
G Slc26a6 solute carrier family 26 member 6 involved_in ISO (PMID:15990874)
(MGI:5514332|PMID:17151144)
RGD PMID:15990874 PMID:17151144 MGI:5514332 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in ISO (MGI:5892167|PMID:28096417) RGD PMID:28096417 MGI:5892167 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
JBrowse link
negative regulation of protein kinase C signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkd diacylglycerol kinase, delta involved_in ISO (MGI:3691361|PMID:17021016) RGD PMID:17021016 MGI:3691361 NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
JBrowse link
G Dgkg diacylglycerol kinase, gamma involved_in ISS
ISO
GO_REF:0000024
(MGI:6431961|PMID:32033984)
UniProt
RGD
PMID:32033984 GO_REF:0000024 MGI:6431961 NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like involved_in ISO (PMID:19666841) RGD PMID:19666841 NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723
JBrowse link
G Myadm myeloid-associated differentiation marker involved_in ISO
IEA
(PMID:23264465)
GO_REF:0000107
RGD
Ensembl
PMID:23264465 GO_REF:0000107 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IMP PMID:20819118 RGD
UniProt
PMID:20819118 PMID:20819118 RGD:8693633, RGD:8693633 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
positive regulation of protein kinase C signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:5523726|PMID:24191038) RGD PMID:24191038 MGI:5523726 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IDA
IMP
PMID:19011682 RGD
BHF-UCL
PMID:18467629 PMID:19011682 RGD:5688343, RGD:5688340 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Cd40 CD40 molecule involved_in ISO (PMID:21410936) RGD PMID:21410936 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:11532940)
Ensembl
RGD
PMID:11532940 GO_REF:0000107 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
JBrowse link
G Mc1r melanocortin 1 receptor involved_in ISO (MGI:4412441|PMID:18292087) RGD PMID:18292087 MGI:4412441 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IMP PMID:20819118 UniProt PMID:20819118 RGD:8693633 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:22057271 RGD:6482746 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:18059339) RGD PMID:18059339 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wnt11 Wnt family member 11 involved_in ISO (PMID:20103596) RGD PMID:20103596 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:19099253) RGD PMID:19099253 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
regulation of protein kinase C signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap12 A-kinase anchoring protein 12 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within ISO (MGI:3777904|PMID:12089068) RGD PMID:12089068 MGI:3777904 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Sez6 seizure related 6 homolog acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1935121|MGI:2385295 (MGI:3654399|PMID:16814779)
PMID:21873635
RGD PMID:16814779 PMID:21873635 MGI:3654399, RGD:13792537 NCBI chr10:62,818,931...62,868,686
Ensembl chr10:62,819,069...62,868,671
JBrowse link
G Sez6l seizure related 6 homolog like acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:104745|MGI:2385295 (MGI:3654399|PMID:16814779)
PMID:21873635
RGD PMID:16814779 PMID:21873635 MGI:3654399, RGD:13792537 NCBI chr12:44,064,628...44,221,815
Ensembl chr12:44,064,935...44,219,663
JBrowse link
G Sez6l2 seizure related 6 homolog like 2 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:104745|MGI:1935121 (MGI:3654399|PMID:16814779)
PMID:21873635
RGD PMID:16814779 PMID:21873635 MGI:3654399, RGD:13792537 NCBI chr 1:181,557,109...181,577,456
Ensembl chr 1:181,557,109...181,577,456
JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO (PMID:24284070) RGD PMID:24284070 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    signaling 7399
      signal transduction 6838
        intracellular signal transduction 2675
          protein kinase C signaling 41
            negative regulation of protein kinase C signaling 5
            positive regulation of protein kinase C signaling 11
            regulation of protein kinase C signaling + 21
Path 2
Term Annotations click to browse term
  biological_process 18877
    biological regulation 13380
      regulation of biological process 12644
        regulation of cellular process 11961
          signal transduction 6838
            intracellular signal transduction 2675
              protein kinase C signaling 41
                negative regulation of protein kinase C signaling 5
                positive regulation of protein kinase C signaling 11
                regulation of protein kinase C signaling + 21
paths to the root