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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA threonylcarbamoyladenosine metabolic process
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Accession:GO:0070525 term browser browse the term
Definition:The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.
Synonyms:exact_synonym: t6A metabolic process;   t6A metabolism;   threonylcarbamoyladenosine metabolism


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tRNA threonylcarbamoyladenosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctag2 cancer/testis antigen 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:143,531,907...143,533,201
Ensembl chr  X:143,531,907...143,533,201 		JBrowse link
G Ctag2l1 cancer/testis antigen 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:152,266,680...152,267,835
Ensembl chr  X:152,266,522...152,267,835 		JBrowse link
G Ctag2l2 cancer/testis antigen 2 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr  X:152,340,658...152,341,853 JBrowse link
G Lage3 L antigen family, member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:152,138,209...152,139,632
Ensembl chr  X:152,138,218...152,139,632 		JBrowse link
G LOC134484033 EKC/KEOPS complex subunit LAGE3-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G LOC134484035 EKC/KEOPS complex subunit LAGE3-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Tp53rka Tp53 tumor protein p53 regulating kinase A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:154,219,672...154,224,841
Ensembl chr 3:154,220,851...154,224,328 		JBrowse link
G Tp53rkb tumor protein p53 regulating kinase B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:155,529,298...155,532,662
Ensembl chr 3:155,529,298...155,532,728 		JBrowse link
mitochondrial tRNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:23042678), (PMID:25925575), (PMID:28888424)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23042678 PMID:25925575 PMID:28888424 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit involved_in ISO (PMID:23042678) RGD PMID:23042678 NCBI chr11:44,584,388...44,589,466
Ensembl chr11:44,584,113...44,589,568 		JBrowse link
G Trmt5 tRNA methyltransferase 5 involved_in ISO
IBA		 (PMID:26189817)
GO_REF:0000033		 RGD
GO_Central		 PMID:26189817 GO_REF:0000033 NCBI chr 6:91,963,558...91,987,660
Ensembl chr 6:91,943,724...91,987,555 		JBrowse link
mitochondrial tRNA modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 acts_upstream_of_or_within ISO MGI:5750452 (PMID:25738458) RGD PMID:25738458 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Mettl8 methyltransferase 8, tRNA N3-cytidine involved_in ISO (PMID:34774131) RGD PMID:34774131 NCBI chr 3:55,731,453...55,863,652
Ensembl chr 3:55,770,167...55,863,676 		JBrowse link
G Trit1 tRNA isopentenyltransferase 1 involved_in ISO (PMID:34774131)
(PMID:24901367)		 RGD PMID:24901367 PMID:34774131 NCBI chr 5:135,293,472...135,341,522
Ensembl chr 5:135,295,330...135,338,764 		JBrowse link
mitochondrial tRNA pseudouridine synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpusd4 RNA pseudouridine synthase D4 involved_in ISO (PMID:28082677) RGD PMID:28082677 NCBI chr 8:33,617,384...33,626,873
Ensembl chr 8:33,617,379...33,626,873 		JBrowse link
mitochondrial tRNA wobble uridine modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mto1 mitochondrial tRNA translation optimization 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
SGD:S000003205 (PMID:14522080)		 GO_Central
RGD		 PMID:14522080 GO_REF:0000033 NCBI chr 8:79,309,681...79,335,231
Ensembl chr 8:79,309,982...79,335,231 		JBrowse link
tRNA threonylcarbamoyladenosine modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gon7 GON7 subunit of KEOPS complex involved_in ISO (PMID:31481669) RGD PMID:31481669 NCBI chr 6:121,882,565...121,898,452
Ensembl chr 6:121,885,694...121,898,643
Ensembl chr 6:121,885,694...121,898,643 		JBrowse link
G Osgep O-sialoglycoprotein endopeptidase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:28805828), (PMID:31481669)		 UniProt
RGD		 PMID:28805828 PMID:31481669 GO_REF:0000024 GO_REF:0000104 NCBI chr15:24,137,149...24,144,568
Ensembl chr15:24,137,153...24,144,568 		JBrowse link
G Osgepl1 O-sialoglycoprotein endopeptidase-like 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:29760464), (PMID:32047918)		 UniProt
RGD		 PMID:29760464 PMID:32047918 GO_REF:0000024 GO_REF:0000104 NCBI chr 9:48,214,995...48,229,440
Ensembl chr 9:48,215,402...48,229,388 		JBrowse link
G Tprkb Tp53rk binding protein involved_in ISO
IBA
ISS		 (PMID:28805828)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:28805828 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:118,342,910...118,357,908
Ensembl chr 4:118,342,945...118,357,901 		JBrowse link
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29760464), (PMID:31481669), (PMID:34545459)		 UniProt
Ensembl
RGD		 PMID:29760464 PMID:31481669 PMID:34545459 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:137,110,244...137,115,127
Ensembl chr 5:137,110,279...137,115,120 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      macromolecule metabolic process 10147
        nucleic acid metabolic process 5149
          RNA metabolic process 4579
            tRNA metabolic process 200
              tRNA threonylcarbamoyladenosine metabolic process 21
                mitochondrial tRNA modification + 8
                tRNA threonylcarbamoyladenosine modification + 5
Path 2
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      primary metabolic process 10923
        nucleobase-containing compound metabolic process 5735
          nucleic acid metabolic process 5149
            RNA metabolic process 4579
              tRNA metabolic process 200
                tRNA threonylcarbamoyladenosine metabolic process 21
                  mitochondrial tRNA modification + 8
                  tRNA threonylcarbamoyladenosine modification + 5
paths to the root