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ONTOLOGY REPORT - ANNOTATIONS


Term:nonhomologous end joining complex
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Accession:GO:0070419 term browser browse the term
Definition:A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.
Synonyms:exact_synonym: NHEJ complex;   non-homologous end joining complex


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nonhomologous end joining complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1c DNA cross-link repair 1C ISO
ISS
(PMID:25941166)
GO_REF:0000024
RGD
UniProt
PMID:25941166 GO_REF:0000024 NCBI chr17:78,782,512...78,812,140
Ensembl chr17:78,783,437...78,812,111
JBrowse link
G Lig4 DNA ligase 4 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20383123), (PMID:25941166)
UniProt
RGD
PMID:20383123, PMID:25941166, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 9:82,230,230...82,327,923
Ensembl chr 9:82,230,232...82,327,534
JBrowse link
G Paxx PAXX, non-homologous end joining factor ISO
IBA
(PMID:25670504), (PMID:25941166)
PMID:21873635
RGD PMID:25670504, PMID:25941166, PMID:21873635 RGD:13792537 NCBI chr 3:2,678,987...2,681,668
Ensembl chr 3:2,678,956...2,680,622
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
JBrowse link
DNA-dependent protein kinase-DNA ligase 4 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig4 DNA ligase 4 ISO
IBA
(MGI:MGI:3052572|PMID:15194694)
PMID:21873635
(PMID:15194694)
RGD PMID:15194694, PMID:21873635 MGI:MGI:3052572, RGD:13792537 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (PMID:15194694) RGD PMID:15194694 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO
IBA
(PMID:15194694)
PMID:21873635
(MGI:MGI:3052572|PMID:15194694)
RGD PMID:15194694, PMID:21873635 MGI:MGI:3052572, RGD:13792537 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 TAS RGD PMID:11966321 RGD:727219 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  cellular_component 20610
    protein-containing complex 6104
      DNA repair complex 37
        nonhomologous end joining complex 8
          DNA-dependent protein kinase-DNA ligase 4 complex 4
          Ku-DNA ligase complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.