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ONTOLOGY REPORT - ANNOTATIONS

Term:NADPH binding
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Accession:GO:0070402 term browser browse the term
Definition:Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
Synonyms:exact_synonym: reduced NADP binding;   reduced nicotinamide adenine dinucleotide phosphate binding


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NADPH binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables IEA
ISO		 GO_REF:0000107
(MGI:5883408|PMID:20124700)		 Ensembl
RGD		 PMID:20124700 GO_REF:0000107 MGI:5883408 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Cbr3 carbonyl reductase 3 enables ISO (PMID:18493841) RGD PMID:18493841 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Cbr4 carbonyl reductase 4 enables ISO
ISS
IEA		 (PMID:19000905), (PMID:25203508)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19000905 PMID:25203508 GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G Cryz crystallin zeta enables IBA
ISO
ISS
IEA		 PMID:21873635
(PMID:17497241)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17497241 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 enables ISO
IEA		 (PMID:15531764)
GO_REF:0000107		 RGD
Ensembl		 PMID:15531764 GO_REF:0000107 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Dhfr dihydrofolate reductase enables ISO (PMID:2303423) RGD PMID:2303423 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dus2 dihydrouridine synthase 2 enables ISO (PMID:26429968) RGD PMID:26429968 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709 		JBrowse link
G Fdxr ferredoxin reductase IDA RGD PMID:10525147 RGD:727285 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase enables ISO (PMID:16756993) RGD PMID:16756993 NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase enables ISO
IEA		 (PMID:10698924)
GO_REF:0000107		 RGD
Ensembl		 PMID:10698924 GO_REF:0000107 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables ISO
ISS
IEA		 (PMID:17540341)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17540341 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
G Lbr lamin B receptor enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:27336722)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27336722 GO_REF:0000024 GO_REF:0000107 NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase enables ISO (PMID:11466310) RGD PMID:11466310 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 enables ISO (PMID:10625700) RGD PMID:10625700 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860 		JBrowse link
G Nos1 nitric oxide synthase 1 IDA RGD PMID:14966111 RGD:1358520 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Qdpr quinoid dihydropteridine reductase enables IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:1639779 PMID:21873635 RGD:5128591, RGD:13792537 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:11377984 RGD:4891997 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 enables ISO (PMID:19349281) RGD PMID:19349281 NCBI chr 6:27,818,327...27,825,753 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20464
    binding 17452
      ion binding 5628
        anion binding 2515
          NADPH binding 19
Path 2
Term Annotations click to browse term
  molecular_function 20464
    binding 17452
      organic cyclic compound binding 6064
        nucleoside phosphate binding 2249
          nucleotide binding 2249
            purine nucleotide binding 2094
              adenyl nucleotide binding 1715
                NADP binding 65
                  NADPH binding 19
paths to the root