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ONTOLOGY REPORT - ANNOTATIONS


Term:NADPH binding
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Accession:GO:0070402 term browser browse the term
Definition:Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
Synonyms:exact_synonym: reduced NADP binding;   reduced nicotinamide adenine dinucleotide phosphate binding



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NADPH binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07068905.1 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 8:817,915...819,124 JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables IEA
ISO
GO_REF:0000107
(MGI:5883408|PMID:20124700)
Ensembl
RGD
PMID:20124700 GO_REF:0000107 MGI:5883408 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Cbr3 carbonyl reductase 3 enables ISO (PMID:18493841) RGD PMID:18493841 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Cbr4 carbonyl reductase 4 enables ISO
ISS
IEA
(PMID:19000905), (PMID:25203508)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:19000905 PMID:25203508 GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712
JBrowse link
G Cryz crystallin zeta enables ISO
ISS
IEA
IBA
(PMID:17497241)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
RGD
UniProt
Ensembl
GO_Central
PMID:17497241 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 enables ISO
IEA
(PMID:15531764)
GO_REF:0000107
RGD
Ensembl
PMID:15531764 GO_REF:0000107 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dhfr dihydrofolate reductase enables ISO (PMID:2303423) RGD PMID:2303423 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dus2 dihydrouridine synthase 2 enables ISO (PMID:26429968) RGD PMID:26429968 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
JBrowse link
G Fdxr ferredoxin reductase IDA RGD PMID:10525147 RGD:727285 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase enables ISO (PMID:16756993) RGD PMID:16756993 NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase enables ISO
IEA
(PMID:10698924)
GO_REF:0000107
RGD
Ensembl
PMID:10698924 GO_REF:0000107 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables ISO
ISS
IEA
(PMID:17540341)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17540341 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Lbr lamin B receptor enables ISS
ISO
IEA
GO_REF:0000024
(PMID:27336722)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:27336722 GO_REF:0000024 GO_REF:0000107 NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase enables ISO (PMID:11466310) RGD PMID:11466310 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 enables ISO (PMID:10625700) RGD PMID:10625700 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860
JBrowse link
G Nos1 nitric oxide synthase 1 IDA RGD PMID:14966111 RGD:1358520 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Qdpr quinoid dihydropteridine reductase enables IMP
IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
RGD
PMID:1639779 GO_REF:0000033 GO_REF:0000118, RGD:5128591 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:11377984 RGD:4891997 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 enables ISO (PMID:19349281) RGD PMID:19349281 NCBI chr 6:27,818,327...27,825,753 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20936
    binding 17987
      small molecule binding 6159
        ion binding 5868
          anion binding 2546
            NADPH binding 20
Path 2
Term Annotations click to browse term
  molecular_function 20936
    binding 17987
      organic cyclic compound binding 6333
        nucleoside phosphate binding 2275
          nucleotide binding 2275
            purine nucleotide binding 2112
              adenyl nucleotide binding 1731
                NADP binding 65
                  NADPH binding 20
paths to the root