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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of ERK1 and ERK2 cascade
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Accession:GO:0070373 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
Synonyms:exact_synonym: down regulation of ERK1 and ERK2 cascade;   downregulation of ERK1 and ERK2 cascade;   negative regulation of ERK1 and ERK2 signaling pathway;   negative regulation of ERK1 and ERK2 signalling pathway;   negative regulation of ERK1/2 cascade
 narrow_synonym: inhibition of ERK1 and ERK2 cascade;   negative regulation of ERK1 cascade;   negative regulation of ERK2 cascade;   negative regulation of MAPK1 cascade;   negative regulation of MAPK3 cascade
 broad_synonym: negative regulation of ERK cascade



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negative regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:104738 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Ace2 angiotensin I converting enzyme 2 IMP RGD PMID:20703229 RGD:9685431 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO
GO_REF:0000024
(PMID:12070119)
UniProt
RGD
PMID:12070119 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ankrd26 ankyrin repeat domain containing 26 acts_upstream_of_or_within ISO MGI:3774418 (MGI:5285770|PMID:21669876) RGD PMID:21669876 MGI:5285770 NCBI chr 4:151,670,604...151,740,032
Ensembl chr 4:151,672,037...151,739,968
JBrowse link
G Arrb1 arrestin, beta 1 IMP RGD PMID:19254952 RGD:5509898 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Atf3 activating transcription factor 3 involved_in ISO (MGI:5297260|PMID:22053207) RGD PMID:22053207 MGI:5297260 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within ISO (MGI:5520006|PMID:23589618) RGD PMID:23589618 MGI:5520006 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618
JBrowse link
G C1ql4 complement C1q like 4 acts_upstream_of_or_within ISO (MGI:5527130|PMID:23449976) RGD PMID:23449976 MGI:5527130 NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678
JBrowse link
G C2h3orf33 similar to human chromosome 3 open reading frame 33 involved_in ISO (PMID:20680465) RGD PMID:20680465 NCBI chr 2:148,376,598...148,404,343
Ensembl chr 2:148,380,581...148,404,387
JBrowse link
G Cav1 caveolin 1 IDA RGD PMID:20172952 RGD:6849300 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit IMP RGD PMID:20505147 RGD:8549538 NCBI chr 1:156,487,279...156,494,277
Ensembl chr 1:156,487,279...156,491,476
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IMP RGD PMID:20505147 RGD:8549538 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit IMP RGD PMID:20505147 RGD:8549538 NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192
JBrowse link
G Cnksr3 Cnksr family member 3 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:4457233|PMID:19567370)
UniProt
Ensembl
RGD
PMID:19567370 GO_REF:0000024 GO_REF:0000107 MGI:4457233 NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635
JBrowse link
G Cryba1 crystallin, beta A1 IMP RGD PMID:21993393 RGD:10059647 NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726
JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:9325302 RGD:2303720 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IDA PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:19903888)
UniProt
RGD
PMID:19903888 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISO
IEA
(PMID:20551903)
GO_REF:0000107
RGD
Ensembl
PMID:20551903 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Dmd dystrophin acts_upstream_of_or_within ISO MGI:1856328 (MGI:3028267|PMID:14718391) RGD PMID:14718391 MGI:3028267 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dusp1 dual specificity phosphatase 1 IMP RGD PMID:17437549 RGD:7771545 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in ISO (MGI:5905244|PMID:25772234) RGD PMID:25772234 MGI:5905244 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dusp26 dual specificity phosphatase 26 involved_in ISO (PMID:16581800) RGD PMID:16581800 NCBI chr16:61,041,784...61,049,319
Ensembl chr16:61,041,792...61,049,051
JBrowse link
G Dusp29 dual specificity phosphatase 29 involved_in ISS
ISO
GO_REF:0000024
(MGI:6450308|PMID:32639872)
UniProt
RGD
PMID:32639872 GO_REF:0000024 MGI:6450308 NCBI chr15:2,593,473...2,634,019
Ensembl chr15:2,593,578...2,633,503
JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in IBA
ISO
PMID:21873635
(PMID:11085983)
RGD PMID:11085983 PMID:21873635 RGD:13792537 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Dusp4 dual specificity phosphatase 4 involved_in ISO
ISS
(PMID:7535768)
GO_REF:0000024
RGD
UniProt
PMID:7535768 GO_REF:0000024 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp6 dual specificity phosphatase 6 involved_in IDA
ISO
IBA
(PMID:18771677)
PMID:21873635
RGD PMID:18771677 PMID:8626780 PMID:21873635 RGD:728656, RGD:13792537 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dusp9 dual specificity phosphatase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821
JBrowse link
G Dynlt1 dynein light chain Tctex-type 1 acts_upstream_of_or_within ISO (MGI:5303025|PMID:22028875) RGD PMID:22028875 MGI:5303025 NCBI chr 1:46,887,017...46,893,956
Ensembl chr 1:46,887,017...46,893,881
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A IMP RGD PMID:22025682 RGD:10755441 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698
JBrowse link
G Epha4 Eph receptor A4 involved_in ISO (PMID:29093007) RGD PMID:29093007 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (MGI:5905277|PMID:11585923) RGD PMID:11585923 MGI:5905277 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IDA RGD PMID:19204184 RGD:9685562 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) RGD PMID:20551903 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fbln1 fibulin 1 involved_in ISO (PMID:11792823) RGD PMID:11792823 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:3774414|MGI:4348628 (MGI:3772618|PMID:18182616), (MGI:5050037|PMID:21258407)
UniProt
RGD
PMID:18182616 PMID:21258407 GO_REF:0000024 MGI:3772618 MGI:5050037 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24337748) RGD PMID:24337748 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA
(PMID:23840305)
GO_REF:0000107
RGD
Ensembl
PMID:23840305 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009411|PMID:16023107)
(PMID:11408560)
BHF-UCL
RGD
PMID:11408560 PMID:16023107 GO_REF:0000024 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:96787 (MGI:3640953|PMID:16691571) RGD PMID:16691571 MGI:3640953 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037
JBrowse link
G Klf4 Kruppel like factor 4 involved_in IMP PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:96432 (MGI:3640953|PMID:16691571)
Ensembl
RGD
PMID:16691571 GO_REF:0000107 MGI:3640953 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lmo3 LIM domain only 3 involved_in ISO (PMID:23823477) RGD PMID:23823477 NCBI chr 4:171,234,686...171,297,677
Ensembl chr 4:171,234,696...171,292,222
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(MGI:2687173|PMID:14525964), (MGI:3044099|PMID:14726379)
UniProt
RGD
PMID:14525964 PMID:14726379 GO_REF:0000024 MGI:2687173 MGI:3044099 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Mir138-1 microRNA 138-1 acts_upstream_of ISO (PMID:21444814) RGD PMID:21444814 NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064
JBrowse link
G Mir138-2 microRNA 138-2 acts_upstream_of ISO (PMID:21444814) RGD PMID:21444814 NCBI chr19:10,674,193...10,674,274
Ensembl chr19:10,674,193...10,674,274
JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir200c microRNA 200c acts_upstream_of ISO (PMID:24205206) RGD PMID:24205206 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir205 microRNA 205 acts_upstream_of ISO (PMID:23974361) RGD PMID:23974361 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:20483747) RGD PMID:20483747 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:23333386) RGD PMID:23333386 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir322 microRNA 322 involved_in ISO RNAcentral:URS00000F6E49_9606 (PMID:23263626) RGD PMID:23263626 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688
JBrowse link
G Mir503 microRNA 503 involved_in ISO RNAcentral:URS00000F0F49_9606 (PMID:23263626) RGD PMID:23263626 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373
JBrowse link
G Ndrg2 NDRG family member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4835375|PMID:19815093)
GO_REF:0000107
RGD
Ensembl
PMID:19815093 GO_REF:0000107 MGI:4835375 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 acts_upstream_of_or_within ISO MGI:4836357 (MGI:5436198|PMID:22503542) RGD PMID:22503542 MGI:5436198 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISO (MGI:5432950|PMID:22763455) RGD PMID:22763455 MGI:5432950 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113
JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:24732013) RGD PMID:24732013 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IMP PMID:20819118 UniProt PMID:20819118 RGD:8693633 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:20179103) RGD PMID:20179103 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Psca prostate stem cell antigen involved_in ISO (PMID:25680266) RGD PMID:25680266 NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IBA
UniProtKB:P97333 (MGI:5490930|PMID:23639442)
PMID:21873635
RGD PMID:23639442 PMID:21873635 MGI:5490930, RGD:13792537 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:3530208|PMID:15696169)
UniProt
RGD
PMID:15696169 PMID:21873635 GO_REF:0000024 MGI:3530208, RGD:13792537 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:P06240 (MGI:3530407|PMID:15661907) RGD PMID:15661907 MGI:3530407 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R involved_in IEA
ISO
GO_REF:0000107
(PMID:21724833)
Ensembl
RGD
PMID:21724833 GO_REF:0000107 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603
JBrowse link
G Ranbp9 RAN binding protein 9 involved_in ISO (PMID:23118896) RGD PMID:23118896 NCBI chr17:21,220,807...21,303,009
Ensembl chr17:21,220,618...21,303,004
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:95516 (MGI:3701731|PMID:16858399) RGD PMID:16858399 MGI:3701731 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984
JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in IDA PMID:19878719 UniProt PMID:19878719 RGD:8553779 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 involved_in ISO (MGI:3041939|PMID:15121846) RGD PMID:15121846 MGI:3041939 NCBI chr  X:76,354,824...76,454,484
Ensembl chr  X:76,353,760...76,454,484
JBrowse link
G Sema6a semaphorin 6A involved_in ISO (PMID:21536891) RGD PMID:21536891 NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954
JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
JBrowse link
G Sirt3 sirtuin 3 IMP RGD PMID:23397292 RGD:9586042 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3689643|PMID:16151019)
Ensembl
RGD
PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:5766647|PMID:26934179), (MGI:6414698|PMID:29501879) RGD PMID:26934179 PMID:29501879 MGI:5766647 MGI:6414698 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414698|PMID:29501879)
UniProt
RGD
PMID:29501879 GO_REF:0000024 MGI:6414698 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within
involved_in
ISO MGI:1099809|MGI:1345138 (MGI:2154590|PMID:11585837), (MGI:5052190|PMID:21764747)
(MGI:3831894|PMID:19043405), (MGI:6414698|PMID:29501879)
RGD PMID:11585837 PMID:19043405 PMID:21764747 PMID:29501879 MGI:2154590 MGI:3831894 MGI:5052190 MGI:6414698 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in
acts_upstream_of_or_within
ISO (PMID:20489163), (PMID:21536891)
(MGI:5693366|PMID:18508928), (MGI:6414698|PMID:29501879)
MGI:1099809|MGI:1345139 (MGI:2154590|PMID:11585837), (MGI:5052190|PMID:21764747)
RGD PMID:11585837 PMID:18508928 PMID:20489163 PMID:21536891 PMID:21764747 More... MGI:2154590 MGI:5052190 MGI:5693366 MGI:6414698 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009
JBrowse link
G Spry3 sprouty RTK signaling antagonist 3 involved_in ISO (MGI:3695236|PMID:16877379) RGD PMID:16877379 MGI:3695236 NCBI chr12:16,663,188...16,673,124
Ensembl chr12:16,663,389...16,672,531
JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004
JBrowse link
G Synj2bp synaptojanin 2 binding protein involved_in ISS
ISO
GO_REF:0000024
(PMID:24025447)
UniProt
RGD
PMID:24025447 GO_REF:0000024 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
JBrowse link
G Tbc1d10c TBC1 domain family, member 10C acts_upstream_of_or_within ISO MGI:1932389 (MGI:5576870|PMID:23109291) RGD PMID:23109291 MGI:5576870 NCBI chr 1:201,476,258...201,484,876
Ensembl chr 1:201,477,157...201,564,920
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:19962668)
Ensembl
RGD
PMID:19962668 GO_REF:0000107 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:4421230|PMID:20051628)
Ensembl
RGD
PMID:20051628 GO_REF:0000107 MGI:4421230 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr9 toll-like receptor 9 acts_upstream_of_or_within ISO MGI:1922072 (MGI:5576870|PMID:23109291) RGD PMID:23109291 MGI:5576870 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in IBA
ISO
PMID:21873635
(PMID:12220502)
RGD PMID:12220502 PMID:21873635 RGD:13792537 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625
JBrowse link
G Vrk3 VRK serine/threonine kinase 3 acts_upstream_of_or_within ISO (MGI:3778226|PMID:18035061) RGD PMID:18035061 MGI:3778226 NCBI chr 1:95,243,344...95,270,780
Ensembl chr 1:95,243,364...95,270,780
JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 involved_in ISO (PMID:17667937) RGD PMID:17667937 NCBI chr17:15,503,672...15,612,479
Ensembl chr17:15,504,261...15,612,479
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    cellular process 18675
      signal transduction 7133
        intracellular signal transduction 2748
          MAPK cascade 859
            negative regulation of MAPK cascade 205
              negative regulation of ERK1 and ERK2 cascade 92
Path 2
Term Annotations click to browse term
  biological_process 20091
    biological regulation 13996
      regulation of biological process 13218
        regulation of cellular process 12482
          signal transduction 7133
            intracellular signal transduction 2748
              MAPK cascade 859
                regulation of MAPK cascade 773
                  negative regulation of MAPK cascade 205
                    negative regulation of ERK1 and ERK2 cascade 92
paths to the root