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ONTOLOGY REPORT - ANNOTATIONS

Term:ERK1 and ERK2 cascade
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Accession:GO:0070371 term browser browse the term
Definition:A MAPK cascade containing at least the ERK1 or ERK2 MAP kinases. It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK1 or ERK2. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier. The ERK1/ERK2 cascade is activated by mitogens, growth factors, G protein-coupled receptors, and results in cellular responses such as cell proliferation, cell differentiation and development.
Comment:Note that this MAPKKK cascade is commonly referred to as the ERK pathway in the literature, but involves only ERK1 or ERK2 and should not be confused with cascades that involve other ERK kinases.
Synonyms:exact_synonym: ERK1 and ERK2 signaling pathway;   ERK1 and ERK2 signalling pathway;   ERK1/2 cascade;   extracellular signal-regulated kinase 1/2 (ERK1/2) cascade;   extracellular signal-regulated kinase 1/2 cascade
 narrow_synonym: ERK1 cascade;   ERK2 cascade;   MAPK1 cascade;   MAPK3 cascade
 broad_synonym: ERK cascade


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ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22729085) Ensembl
MGI		 PMID:22729085 GO_REF:0000107 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:21367774 RGD:5129174 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G ANKRD26 ankyrin repeat domain containing 26 acts_upstream_of ISO (PMID:21669876) MGI PMID:21669876 NCBI chr10:27,111,909...27,210,001
Ensembl chr10:27,478,452...27,572,261 		JBrowse link
G APOA1 apolipoprotein A1 NOT|involved_in ISO (PMID:23726972) UniProt PMID:23726972 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO (PMID:22025725) MGI PMID:22025725 NCBI chr19:38,854,243...38,882,034
Ensembl chr19:47,358,281...47,384,716 		JBrowse link
G AVP arginine vasopressin involved_in ISO (PMID:18402937) UniProt PMID:18402937 NCBI chr20:3,169,094...3,172,900 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of ISO (PMID:15199148), (PMID:23616533)
(PMID:16342120)
(PMID:23334952)
(PMID:15784729)		 MGI PMID:15199148 PMID:15784729 PMID:16342120 PMID:23334952 PMID:23616533 NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115 		JBrowse link
G C1QL4 complement C1q like 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23449976) Ensembl
MGI		 PMID:23449976 GO_REF:0000107 NCBI chr12:39,414,635...39,419,422
Ensembl chr12:40,301,076...40,304,503 		JBrowse link
G C1QTNF3 C1q and TNF related 3 acts_upstream_of ISO (PMID:20952387) MGI PMID:20952387 NCBI chr 5:76,292,679...76,325,064
Ensembl chr 5:81,687,891...81,742,003 		JBrowse link
G CCKBR cholecystokinin B receptor ISO RGD PMID:17226751 RGD:2311329 NCBI chr11:6,393,435...6,405,821
Ensembl chr11:6,075,816...6,088,145 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:12413953 RGD:4145648 NCBI chr 3:46,147,928...46,172,947
Ensembl chr 3:47,253,878...47,278,630 		JBrowse link
G CD2AP CD2 associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28878342) Ensembl
MGI		 PMID:28878342 GO_REF:0000107 NCBI chr 6:47,065,284...47,210,746
Ensembl chr 6:48,328,863...48,474,163 		JBrowse link
G CNTNAP2 contactin associated protein 2 involved_in ISO (PMID:32675284) MGI PMID:32675284 NCBI chr 7:137,858,607...140,150,820
Ensembl chr 7:150,345,240...152,626,818 		JBrowse link
G CTSH cathepsin H involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:57,893,379...57,917,194
Ensembl chr15:76,852,668...76,876,976 		JBrowse link
G EDN1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460 		JBrowse link
G ENO1 enolase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21764747)
(PMID:15130516)
(PMID:17202188)		 Ensembl
MGI		 PMID:15130516 PMID:17202188 PMID:21764747 GO_REF:0000107 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G FGF18 fibroblast growth factor 18 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11741978) Ensembl
MGI		 PMID:11741978 GO_REF:0000107 NCBI chr 5:166,765,061...166,802,277 JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of ISO (PMID:16858399) MGI PMID:16858399 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G FGF23 fibroblast growth factor 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 acts_upstream_of ISO (PMID:17202188) MGI PMID:17202188 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692 		JBrowse link
G FLCN folliculin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18182616)
(PMID:21258407)		 Ensembl
MGI		 PMID:18182616 PMID:21258407 GO_REF:0000107 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160 		JBrowse link
G GRB10 growth factor receptor bound protein 10 involved_in
acts_upstream_of_or_within_negative_effect		 IEA
ISO		 (PMID:26941017) Ensembl
MGI		 PMID:26941017 GO_REF:0000107 NCBI chr 7:51,230,945...51,434,560
Ensembl chr 7:51,474,166...51,666,638 		JBrowse link
G HESX1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31761678) Ensembl
MGI		 PMID:31761678 GO_REF:0000107 NCBI chr 3:57,131,419...57,161,205
Ensembl chr 3:58,341,965...58,370,347 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:118,362,719...118,381,253
Ensembl chr2B:237,153,709...237,170,591 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28878342) Ensembl
MGI		 PMID:28878342 GO_REF:0000107 NCBI chr11:67,302,066...67,317,785
Ensembl chr11:70,527,017...70,540,846 		JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18604197) Ensembl
MGI		 PMID:18604197 GO_REF:0000107 NCBI chr 1:131,869,002...131,916,554
Ensembl chr 1:135,695,602...135,740,564 		JBrowse link
G ITGAV integrin subunit alpha V involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:73,880,962...73,972,486
Ensembl chr2B:191,680,655...191,773,028 		JBrowse link
G KARS1 lysyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:56,196,867...56,216,909
Ensembl chr16:75,545,002...75,565,043 		JBrowse link
G LOC100975566 butyrophilin subfamily 2 member A2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23589618) Ensembl
MGI		 PMID:23589618 GO_REF:0000107 NCBI chr 6:26,215,215...26,227,261
Ensembl chr 6:26,873,828...26,885,592 		JBrowse link
G LOC100977210 galectin-9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 acts_upstream_of_or_within ISO (PMID:25100655) MGI PMID:25100655 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25100655) Ensembl
MGI		 PMID:25100655 GO_REF:0000107 NCBI chr19:3,114,445...3,148,619
Ensembl chr19:4,064,626...4,097,933 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19047410) Ensembl
MGI		 PMID:19047410 GO_REF:0000107 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19047410) Ensembl
MGI		 PMID:19047410 GO_REF:0000107 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MOS MOS proto-oncogene, serine/threonine kinase involved_in ISO (PMID:12533425) AgBase PMID:12533425 NCBI chr 8:52,559,066...52,560,362
Ensembl chr 8:49,930,077...49,931,117 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863 		JBrowse link
G NLRP12 NLR family pyrin domain containing 12 acts_upstream_of ISO (PMID:22503542) MGI PMID:22503542 NCBI chr19:50,735,124...50,765,556
Ensembl chr19:59,582,005...59,614,436 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G OXTR oxytocin receptor ISO RGD PMID:10497238 RGD:2304226 NCBI chr 3:8,701,344...8,721,706 JBrowse link
G PTGER4 prostaglandin E receptor 4 involved_in ISO PMID:19233324 UniProt PMID:19233324 RGD:8554254 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16858399) Ensembl
MGI		 PMID:16858399 GO_REF:0000107 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11894098)
(PMID:18261938)		 Ensembl
MGI		 PMID:11894098 PMID:18261938 GO_REF:0000107 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268 		JBrowse link
G SMAD4 SMAD family member 4 ISO RGD PMID:11401854 RGD:12903275 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISO (MGI:5285125|PMID:21512138) UniProt PMID:21512138 MGI:5285125 NCBI chr17:66,028,737...66,034,122 JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21764747) Ensembl
MGI		 PMID:21764747 GO_REF:0000107 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21764747) Ensembl
MGI		 PMID:21764747 GO_REF:0000107 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408 		JBrowse link
G TBC1D10C TBC1 domain family member 10C involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23109291) Ensembl
MGI		 PMID:23109291 GO_REF:0000107 NCBI chr11:62,762,075...62,768,569
Ensembl chr11:66,073,830...66,080,019 		JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of ISO (PMID:22033934) MGI PMID:22033934 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,750,835...23,784,740 JBrowse link
G WNK4 WNK lysine deficient protein kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,520,448...14,537,799
Ensembl chr17:14,746,365...14,762,423 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta acts_upstream_of_or_within ISO (PMID:29118970) MGI PMID:29118970 NCBI chr 8:97,560,251...97,595,117
Ensembl chr 8:99,730,393...99,762,990 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in ISO (PMID:25106868) UniProt PMID:25106868 NCBI chr2A:43,311,744...43,315,928 JBrowse link
negative regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22729085) Ensembl
MGI		 PMID:22729085 GO_REF:0000107 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941 		JBrowse link
G ACE2 angiotensin converting enzyme 2 ISO RGD PMID:20703229 RGD:9685431 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
G ANKRD26 ankyrin repeat domain containing 26 acts_upstream_of_or_within ISO (PMID:21669876) MGI PMID:21669876 NCBI chr10:27,111,909...27,210,001
Ensembl chr10:27,478,452...27,572,261 		JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:19254952 RGD:5509898 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G ATF3 activating transcription factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:188,176,728...188,188,842
Ensembl chr 1:193,036,793...193,049,150 		JBrowse link
G C1QL4 complement C1q like 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23449976) Ensembl
MGI		 PMID:23449976 GO_REF:0000107 NCBI chr12:39,414,635...39,419,422
Ensembl chr12:40,301,076...40,304,503 		JBrowse link
G C2H3orf33 chromosome 2 C3orf33 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:152,818,445...152,861,945
Ensembl chr 3:160,870,570...160,912,955 		JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:20172952 RGD:6849300 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit ISO RGD PMID:20505147 RGD:8549538 NCBI chr11:3,543,450...3,552,036
Ensembl chr11:3,651,580...3,656,780 		JBrowse link
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit ISO RGD PMID:20505147 RGD:8549538 NCBI chr 4:34,654,043...34,675,984
Ensembl chr 4:40,509,475...40,528,869 		JBrowse link
G CNKSR3 CNKSR family member 3 involved_in ISO (MGI:4457233|PMID:19567370) UniProt PMID:19567370 MGI:4457233 NCBI chr 6:152,221,458...152,326,885 JBrowse link
G CRYBA1 crystallin beta A1 ISO RGD PMID:21993393 RGD:10059647 NCBI chr17:27,522,647...27,530,767
Ensembl chr17:28,032,809...28,040,525 		JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:9325302 RGD:2303720 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in ISO PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987 		JBrowse link
G DMD dystrophin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14718391) Ensembl
MGI		 PMID:14718391 GO_REF:0000107 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO RGD PMID:17437549 RGD:7771545 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960 		JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G DUSP26 dual specificity phosphatase 26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:32,906,182...32,915,015
Ensembl chr 8:30,091,092...30,100,699 		JBrowse link
G DUSP29 dual specificity phosphatase 29 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:71,566,439...71,587,499
Ensembl chr10:74,230,734...74,266,565 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:13,618,860...13,631,743
Ensembl chr17:13,784,594...13,797,045 		JBrowse link
G DUSP4 dual specificity phosphatase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:28,623,777...28,641,432
Ensembl chr 8:25,819,989...25,834,332 		JBrowse link
G DUSP6 dual specificity phosphatase 6 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:8626780 GO_REF:0000107 GO_REF:0000118 RGD:728656 NCBI chr12:86,875,289...86,879,731
Ensembl chr12:90,195,482...90,200,321 		JBrowse link
G DYNLT1 dynein light chain Tctex-type 1 acts_upstream_of_or_within ISO (PMID:22028875) MGI PMID:22028875 NCBI chr 6:156,530,068...156,538,346 JBrowse link
G EIF3A eukaryotic translation initiation factor 3 subunit A ISO RGD PMID:22025682 RGD:10755441 NCBI chr10:115,608,394...115,654,586
Ensembl chr10:119,033,253...119,072,889 		JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:27,077,551...27,085,437
Ensembl chr2A:27,166,747...27,174,525 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790 		JBrowse link
G EPHB2 EPH receptor B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:19204184 RGD:9685562 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G EZR ezrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:156,656,146...156,709,986
Ensembl chr 6:161,670,483...161,723,102 		JBrowse link
G FBLN1 fibulin 1 involved_in ISO (PMID:11792823) UniProt PMID:11792823 NCBI chr22:26,390,379...26,488,737
Ensembl chr22:44,582,843...44,666,011 		JBrowse link
G FLCN folliculin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18182616)
(PMID:21258407)		 Ensembl
MGI		 PMID:18182616 PMID:21258407 GO_REF:0000107 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160 		JBrowse link
G GBP1 guanylate binding protein 1 involved_in ISO (PMID:24337748) UniProt PMID:24337748 NCBI chr 1:91,763,835...91,776,843
Ensembl chr 1:90,467,260...90,528,491 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO (PMID:23840305) AgBase PMID:23840305 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155 		JBrowse link
G KLF4 KLF transcription factor 4 involved_in ISO PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797 		JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16691571) Ensembl
MGI		 PMID:16691571 GO_REF:0000107 NCBI chr22:11,276,576...11,282,972
Ensembl chr22:29,078,862...29,095,608 		JBrowse link
G LMO3 LIM domain only 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:16,544,474...16,605,925
Ensembl chr12:16,902,025...16,997,809 		JBrowse link
G LOC100975566 butyrophilin subfamily 2 member A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23589618) Ensembl
MGI		 PMID:23589618 GO_REF:0000107 NCBI chr 6:26,215,215...26,227,261
Ensembl chr 6:26,873,828...26,885,592 		JBrowse link
G LOC100977072 neuronal acetylcholine receptor subunit alpha-7 ISO RGD PMID:20505147 RGD:8549538 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194 		JBrowse link
G LOC100986336 twinfilin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G NDRG2 NDRG family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19815093) Ensembl
MGI		 PMID:19815093 GO_REF:0000107 NCBI chr14:1,831,764...1,840,819
Ensembl chr14:19,913,674...19,967,470 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:68,694,468...68,715,157
Ensembl chr17:74,250,406...74,271,234 		JBrowse link
G NLRP12 NLR family pyrin domain containing 12 acts_upstream_of_or_within ISO (PMID:22503542) MGI PMID:22503542 NCBI chr19:50,735,124...50,765,556
Ensembl chr19:59,582,005...59,614,436 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:274,904...281,590
Ensembl chr11:319,082...325,888 		JBrowse link
G PHB1 prohibitin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790 		JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 involved_in ISO PMID:20819118 UniProt PMID:20819118 RGD:8693633 NCBI chr18:56,084,851...56,338,551 JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853 		JBrowse link
G PSCA prostate stem cell antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:139,384,002...139,394,993
Ensembl chr 8:142,435,849...142,438,401 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G PTPRR protein tyrosine phosphatase receptor type R involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:68,148,200...68,430,618
Ensembl chr12:70,915,951...71,196,732 		JBrowse link
G RANBP9 RAN binding protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:13,466,063...13,556,303
Ensembl chr 6:13,837,308...13,926,693 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16858399) Ensembl
MGI		 PMID:16858399 GO_REF:0000107 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G RGS14 regulator of G protein signaling 14 involved_in ISO PMID:19878719 UniProt PMID:19878719 RGD:8553779 NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453 		JBrowse link
G RPS6KA6 ribosomal protein S6 kinase A6 involved_in ISO (MGI:3041939|PMID:15121846) UniProt PMID:15121846 MGI:3041939 NCBI chr  X:73,131,457...73,261,906
Ensembl chr  X:83,243,957...83,373,194 		JBrowse link
G SEMA6A semaphorin 6A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:111,793,272...111,924,937
Ensembl chr 5:117,592,313...117,651,098 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106 		JBrowse link
G SIRT3 sirtuin 3 ISO RGD PMID:23397292 RGD:9586042 NCBI chr11:210,052...233,969
Ensembl chr11:255,191...278,732 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359 		JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (MGI:6414698|PMID:29501879) UniProt PMID:29501879 MGI:6414698 NCBI chr2A:65,380,608...65,503,139
Ensembl chr2A:66,503,260...66,624,840 		JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 involved_in ISO (MGI:6414698|PMID:29501879) UniProt PMID:29501879 MGI:6414698 NCBI chr19:35,482,436...35,490,745
Ensembl chr19:44,054,053...44,061,962 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21764747)
(PMID:11585837)		 Ensembl
MGI		 PMID:11585837 PMID:21764747 GO_REF:0000107 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21764747)
(PMID:11585837)		 Ensembl
MGI		 PMID:11585837 PMID:21764747 GO_REF:0000107 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408 		JBrowse link
G SPRY3 sprouty RTK signaling antagonist 3 involved_in ISO (MGI:3695236|PMID:16877379) UniProt PMID:16877379 MGI:3695236 NCBI chr  X:145,080,299...145,239,922
Ensembl chr  X:155,131,596...155,132,462 		JBrowse link
G SYNJ2BP synaptojanin 2 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:50,958,861...51,009,395
Ensembl chr14:69,835,548...69,879,537 		JBrowse link
G TBC1D10C TBC1 domain family member 10C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23109291) Ensembl
MGI		 PMID:23109291 GO_REF:0000107 NCBI chr11:62,762,075...62,768,569
Ensembl chr11:66,073,830...66,080,019 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:146,457,347...146,514,515
Ensembl chr 5:152,459,868...152,510,540 		JBrowse link
G VRK3 VRK serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18035061) Ensembl
MGI		 PMID:18035061 GO_REF:0000107 NCBI chr19:46,988,994...47,037,962
Ensembl chr19:55,904,653...55,953,505 		JBrowse link
G WNK2 WNK lysine deficient protein kinase 2 involved_in ISO (PMID:17667937) UniProt PMID:17667937 NCBI chr 9:64,307,620...64,444,141
Ensembl chr 9:92,372,410...92,507,916 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
positive regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:3662940|PMID:16908670) Alzheimers_University_of_Toronto PMID:16908670 MGI:3662940 NCBI chr19:62,811...77,897
Ensembl chr19:1,018,095...1,042,104 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18827006) Ensembl
MGI		 PMID:18827006 GO_REF:0000107 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18827006) MGI PMID:18827006 NCBI chr 1:154,586,423...154,711,621
Ensembl chr 1:158,280,994...158,313,915 		JBrowse link
G ACKR3 atypical chemokine receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22956548) Ensembl
MGI		 PMID:22956548 GO_REF:0000107 NCBI chr2B:123,795,664...123,810,067
Ensembl chr2B:242,666,173...242,667,261 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle ISO RGD PMID:24204762 RGD:12879446 NCBI chr10:85,660,983...85,678,729
Ensembl chr10:89,164,344...89,182,080 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:23389627) RGD
AgBase		 PMID:23389627 PMID:23688779 RGD:13703057 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in ISO PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G AKAP12 A-kinase anchoring protein 12 ISO RGD PMID:19937403 RGD:14348968 NCBI chr 6:149,058,350...149,176,710
Ensembl chr 6:153,757,081...153,873,925 		JBrowse link
G ALKAL1 ALK and LTK ligand 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:48,957,611...48,989,157
Ensembl chr 8:46,341,310...46,372,344 		JBrowse link
G ALKAL2 ALK and LTK ligand 2 involved_in ISO (PMID:26418745) UniProt PMID:26418745 NCBI chr2A:272,597...281,725 JBrowse link
G ALOX15 arachidonate 15-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669 		JBrowse link
G ANGPT1 angiopoietin 1 involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 (PMID:18425120) Ensembl
GO_Central		 PMID:18425120 GO_REF:0000107 NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783 		JBrowse link
G APELA apelin receptor early endogenous ligand involved_in ISO PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chr 4:157,125,485...157,145,999
Ensembl chr 4:169,176,910...169,195,553 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G APP amyloid beta precursor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G ARHGAP8 Rho GTPase activating protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:25,650,927...25,755,578
Ensembl chr22:43,760,203...43,820,836
Ensembl chr22:43,760,203...43,820,836 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299 		JBrowse link
G ARRB1 arrestin beta 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:19289825 GO_REF:0000107 GO_REF:0000118 RGD:5509998 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G ARRB2 arrestin beta 2 involved_in IEA
ISO		 Ensembl
TreeGrafter
RGD		 PMID:19014370 PMID:19171933 PMID:19254952 PMID:28274926 GO_REF:0000107 GO_REF:0000118 RGD:13506828 RGD:401938609 RGD:5509898 RGD:5510006 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517 		JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c ISO RGD PMID:17845832 RGD:14700553 NCBI chr16:1,370,460...1,376,775
Ensembl chr16:2,613,096...2,619,204 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18692041) Ensembl
MGI		 PMID:18692041 GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G BMPER BMP binding endothelial regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:34,508,583...34,759,860
Ensembl chr 7:34,903,178...35,152,110 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15199148), (PMID:23616533)
(PMID:23334952)
(PMID:16342120)
(PMID:22892241)
(PMID:15784729), (PMID:18228248)		 RGD
MGI
Ensembl		 PMID:15199148 PMID:15784729 PMID:16342120 PMID:18228248 PMID:19720729 More... GO_REF:0000107 RGD:2315869 NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115 		JBrowse link
G C1QTNF3 C1q and TNF related 3 acts_upstream_of_or_within ISO (PMID:20952387) MGI PMID:20952387 NCBI chr 5:76,292,679...76,325,064
Ensembl chr 5:81,687,891...81,742,003 		JBrowse link
G C3 complement C3 ISO RGD PMID:18178156 RGD:5129534 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699 		JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:44,293,612...44,310,430
Ensembl chr19:52,950,317...52,966,146 		JBrowse link
G CALCR calcitonin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:85,382,167...85,532,562
Ensembl chr 7:98,975,906...99,047,162 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:18385282 RGD:6907067 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,432,709...107,446,271
Ensembl chr 9:136,416,279...136,424,756 		JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:22192592 RGD:7207059 NCBI chr 3:119,278,071...119,383,901
Ensembl chr 3:126,252,765...126,285,268 		JBrowse link
G CAVIN3 caveolae associated protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24069528) Ensembl
MGI		 PMID:24069528 GO_REF:0000107 NCBI chr11:6,451,364...6,453,206
Ensembl chr11:6,133,656...6,135,485 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,545,248...34,546,801
Ensembl chr 9:35,353,768...35,354,924 		JBrowse link
G CCN2 cellular communication network factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:46,107,526...46,114,229
Ensembl chr 3:47,214,688...47,215,755 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865 		JBrowse link
G CD4 CD4 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:6,920,587...6,951,814
Ensembl chr12:6,834,011...6,864,204 		JBrowse link
G CD44 CD44 molecule (IN blood group) involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009 		JBrowse link
G CD74 CD74 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:23412386 RGD:11341713 NCBI chr2B:88,373,057...88,429,959
Ensembl chr2B:206,528,943...206,577,045 		JBrowse link
G CHI3L1 chitinase 3 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:178,778,081...178,789,704
Ensembl chr 1:183,075,312...183,083,229 		JBrowse link
G CIB1 calcium and integrin binding 1 involved_in ISO (MGI:3818804|PMID:17975111) UniProt PMID:17975111 MGI:3818804 NCBI chr15:68,919,377...68,923,213 JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16399079) Ensembl
MGI
TreeGrafter		 PMID:16399079 GO_REF:0000107 GO_REF:0000118 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858 		JBrowse link
G CSF1R colony stimulating factor 1 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415 		JBrowse link
G CSF2 colony stimulating factor 2 involved_in ISO (PMID:24520418) GO_Central PMID:24520418 NCBI chr 5:127,496,951...127,499,325
Ensembl chr 5:133,660,775...133,663,146 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 acts_upstream_of_or_within ISO (PMID:22956548) MGI PMID:22956548 NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231 		JBrowse link
G CXCL17 C-X-C motif chemokine ligand 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:39,315,929...39,331,651
Ensembl chr19:47,908,179...47,922,120 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 acts_upstream_of_or_within ISO (PMID:20376365) MGI PMID:20376365 NCBI chr2B:23,744,271...23,748,106
Ensembl chr2B:140,181,829...140,189,647 		JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO RGD PMID:21055410 RGD:5144006 NCBI chr13:29,796,598...29,853,676
Ensembl chr13:48,551,757...48,552,797 		JBrowse link
G DCC DCC netrin 1 receptor ISO RGD PMID:15811950 RGD:2314384 NCBI chr18:45,717,924...46,913,998
Ensembl chr18:49,268,812...50,255,155 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:26674152 RGD:11554781 NCBI chr 1:138,048,730...138,200,426
Ensembl chr 1:141,932,158...141,990,766 		JBrowse link
G DENND2B DENN domain containing 2B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9632734) MGI
TreeGrafter		 PMID:9632734 GO_REF:0000118 NCBI chr11:8,817,897...9,039,913
Ensembl chr11:8,560,468...8,617,257 		JBrowse link
G DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:24,937,091...24,965,423
Ensembl chr2A:25,032,836...25,061,149 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18809670 RGD:2311559 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G DSTYK dual serine/threonine and tyrosine protein kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:180,750,987...180,820,096
Ensembl chr 1:185,041,994...185,107,041 		JBrowse link
G DUSP15 dual specificity phosphatase 15 involved_in ISO PMID:27891578 UniProt PMID:27891578 RGD:12903239 NCBI chr20:28,141,174...28,164,287
Ensembl chr20:29,284,838...29,293,367 		JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:16543720 RGD:4892323 NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497 		JBrowse link
G EGF epidermal growth factor ISO RGD PMID:17310240 RGD:1626216 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460 		JBrowse link
G EGFR epidermal growth factor receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615 		JBrowse link
G EPO erythropoietin ISO RGD PMID:21749867 RGD:10400910 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974 		JBrowse link
G EPOR erythropoietin receptor ISO RGD PMID:21749867 RGD:10400910 NCBI chr19:10,925,148...10,931,955
Ensembl chr19:11,635,248...11,642,383 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:17928626 RGD:5128669 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:17928626 PMID:24440742 RGD:10045880 RGD:5128669 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303 		JBrowse link
G F2R coagulation factor II thrombin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,110,170...39,129,688
Ensembl chr 5:39,110,170...39,129,688 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351 		JBrowse link
G FERMT2 FERM domain containing kindlin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:33,453,983...33,547,721
Ensembl chr14:51,737,188...51,829,766 		JBrowse link
G FFAR4 free fatty acid receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:90,312,647...90,336,115
Ensembl chr10:93,823,004...93,860,262 		JBrowse link
G FGA fibrinogen alpha chain involved_in ISO (PMID:10903502), (PMID:19193866) BHF-UCL PMID:10903502 PMID:19193866 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21764747)
(PMID:17202188)
(PMID:15130516)		 Ensembl
MGI
TreeGrafter		 PMID:15130516 PMID:17202188 PMID:21764747 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G FGF18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11741978) Ensembl
MGI		 PMID:11741978 GO_REF:0000107 NCBI chr 5:166,765,061...166,802,277 JBrowse link
G FGF19 fibroblast growth factor 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:64,794,157...64,800,512
Ensembl chr11:68,085,306...68,090,028 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:16858399)
(MGI:6414698|PMID:29501879)
(PMID:17167778)		 RGD
MGI
UniProt		 PMID:16858399 PMID:17167778 PMID:19952283 PMID:29501879 MGI:6414698 RGD:2325174 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G FGF20 fibroblast growth factor 20 acts_upstream_of_or_within ISO PMID:12704805 MGI PMID:12704805 RGD:8553960 NCBI chr 8:16,205,791...16,216,257
Ensembl chr 8:13,151,867...13,161,216 		JBrowse link
G FGF21 fibroblast growth factor 21 involved_in ISO (PMID:17623664) UniProt PMID:17623664 NCBI chr19:45,755,466...45,758,472 JBrowse link
G FGF23 fibroblast growth factor 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000 		JBrowse link
G FGF4 fibroblast growth factor 4 involved_in ISO (PMID:17167778) UniProt PMID:17167778 NCBI chr11:64,866,649...64,871,031 JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24431450) Ensembl
MGI		 PMID:24431450 GO_REF:0000107 NCBI chr10:98,372,251...98,378,811
Ensembl chr10:101,844,792...101,853,916 		JBrowse link
G FGFBP3 fibroblast growth factor binding protein 3 involved_in ISO (MGI:4949582|PMID:20851768) UniProt PMID:20851768 MGI:4949582 NCBI chr10:88,655,350...88,657,282 JBrowse link
G FGFR2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (PMID:17202188) MGI PMID:17202188 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605 		JBrowse link
G FGG fibrinogen gamma chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G FGL1 fibrinogen like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:17,083,524...17,128,152
Ensembl chr 8:14,035,855...14,066,956 		JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:175,804,728...175,852,703
Ensembl chr 5:183,115,856...183,149,006 		JBrowse link
G FPR2 formyl peptide receptor 2 involved_in ISO (PMID:20141570) ARUK-UCL PMID:20141570 NCBI chr19:48,663,622...48,715,535 JBrowse link
G FSHR follicle stimulating hormone receptor involved_in ISO (PMID:24058690) UniProt PMID:24058690 NCBI chr2A:49,088,450...49,287,688
Ensembl chr2A:50,008,328...50,207,258 		JBrowse link
G GAREM1 GRB2 associated regulator of MAPK1 subtype 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:25,470,702...25,678,146
Ensembl chr18:29,065,053...29,272,231 		JBrowse link
G GAS6 growth arrest specific 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15184064) MGI
Ensembl		 PMID:15184064 GO_REF:0000107 Ensembl chr13:113,968,843...114,009,562 JBrowse link
G GCG glucagon involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:49,436,379...49,446,559
Ensembl chr2B:166,806,016...166,811,155 		JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,357,919...10,470,512
Ensembl chr 6:10,626,891...10,750,975 		JBrowse link
G GLIPR2 GLI pathogenesis related 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:35,986,341...36,013,662
Ensembl chr 9:36,787,649...36,814,812 		JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:11495629 RGD:728462 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988 		JBrowse link
G GPBAR1 G protein-coupled bile acid receptor 1 ISO RGD PMID:28543567 RGD:14700993 NCBI chr2B:105,520,364...105,523,229
Ensembl chr2B:224,120,127...224,121,119 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO (MGI:5141337|PMID:21673097), (MGI:5512928|PMID:23545157)
(PMID:20551055), (PMID:21427217)
PMID:23283935
PMID:23907461		 UniProt
RGD		 PMID:19717735 PMID:20445128 PMID:20551055 PMID:21427217 PMID:21673097 More... MGI:5141337 MGI:5512928 RGD:4892081 RGD:4892084 RGD:8553898 RGD:8553942 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G GPNMB glycoprotein nmb involved_in ISO (MGI:3768878|PMID:18036345) ParkinsonsUK-UCL PMID:18036345 MGI:3768878 NCBI chr 7:23,931,220...23,959,687
Ensembl chr 7:23,539,928...23,568,624 		JBrowse link
G GPR183 G protein-coupled receptor 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:80,461,908...80,475,046
Ensembl chr13:99,601,220...99,602,305 		JBrowse link
G GPR55 G protein-coupled receptor 55 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:118,159,511...118,163,334
Ensembl chr2B:236,958,210...236,959,169 		JBrowse link
G HAND2 heart and neural crest derivatives expressed 2 involved_in ISO (PMID:24161931) BHF-UCL PMID:24161931 NCBI chr 4:165,755,000...165,758,735 JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:152,486,125...152,514,004
Ensembl chr 5:159,108,915...159,131,007 		JBrowse link
G HCRTR1 hypocretin receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22028875) Ensembl
MGI		 PMID:22028875 GO_REF:0000107 NCBI chr 1:30,901,772...30,913,633
Ensembl chr 1:31,919,980...31,928,290 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:17161379 RGD:5508698 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in ISO
IEA		 RGD
Ensembl		 PMID:18163378 GO_REF:0000107 RGD:2314843 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A involved_in IEA
ISO		 Ensembl
RGD		 PMID:24997405 GO_REF:0000107 RGD:401938605 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:118,362,719...118,381,253
Ensembl chr2B:237,153,709...237,170,591 		JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:103,673,172...103,999,133
Ensembl chr  X:114,199,485...114,503,201 		JBrowse link
G IAPP islet amyloid polypeptide involved_in ISO (PMID:22500019) ARUK-UCL PMID:22500019 NCBI chr12:64,918,000...64,925,191
Ensembl chr12:67,520,986...67,528,103 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:19578119), (PMID:24508636) UniProt PMID:19578119 PMID:24508636 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:16595703 RGD:2311095 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:15671867 RGD:1358666 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL26 interleukin 26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,710,066...65,734,659
Ensembl chr12:68,495,807...68,519,637 		JBrowse link
G IL6 interleukin 6 ISO Phosphorylation of STAT3, ERK1/2 RGD PMID:19061939 PMID:20227492 RGD:2306937 RGD:5128677 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:27477354 RGD:151665478 NCBI chr 7:42,538,591...42,556,578
Ensembl chr 7:42,580,730...42,595,097 		JBrowse link
G INS insulin acts_upstream_of_or_within ISO (PMID:12059784) MGI PMID:12059784 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO RGD PMID:17620283 RGD:4892659 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:25224220) MGI PMID:25224220 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G KDR kinase insert domain receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109 		JBrowse link
G LOC100967833 tyrosine-protein phosphatase non-receptor type 11-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:104,237,567...104,240,285 JBrowse link
G LOC100977072 neuronal acetylcholine receptor subunit alpha-7 involved_in ISO PMID:17898229
(MGI:5819349|PMID:17898229)
(MGI:4437154|PMID:20164328)
(MGI:5825438|PMID:11404397)		 ARUK-UCL PMID:11404397 PMID:17898229 PMID:20164328 MGI:4437154 MGI:5819349 MGI:5825438 RGD:12050111 RGD:12790656 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194 		JBrowse link
G LOC100977210 galectin-9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G LOC100983286 olfactory receptor 2AT4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:70,147,876...70,156,223
Ensembl chr11:73,453,301...73,454,264 		JBrowse link
G LOC100986475 metallothionein-2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:36,894,853...36,895,826
Ensembl chr16:56,007,922...56,028,093 		JBrowse link
G LOC100991346 D-dopachrome decarboxylase involved_in ISO (PMID:21817065) BHF-UCL PMID:21817065
G LOC100992193 protein S100-A7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:128,812,685...128,813,961
Ensembl chr 1:132,436,200...132,444,820 		JBrowse link
G LOC100992309 C-C motif chemokine 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:20,704,738...20,706,641
Ensembl chr17:21,000,709...21,002,610 		JBrowse link
G LRP1 LDL receptor related protein 1 ISO RGD PMID:24865476 RGD:13800516 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512 		JBrowse link
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,253,814...35,273,739
Ensembl chr12:36,038,634...36,058,200 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MFAP3 microfibril associated protein 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:149,440,427...149,458,929
Ensembl chr 5:155,438,476...155,456,890 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,318,455...10,428,469 JBrowse link
G MIF macrophage migration inhibitory factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009 		JBrowse link
G MOS MOS proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:52,559,066...52,560,362
Ensembl chr 8:49,930,077...49,931,117 		JBrowse link
G MT3 metallothionein 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093 		JBrowse link
G MTURN maturin, neural progenitor differentiation regulator homolog involved_in ISO (PMID:24681962) UniProt PMID:24681962 NCBI chr 7:30,766,592...30,794,436 JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:23354122 RGD:12798521 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618 		JBrowse link
G NDRG4 NDRG family member 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:38,729,616...38,780,173
Ensembl chr16:57,857,414...57,907,557 		JBrowse link
G NECAB2 N-terminal EF-hand calcium binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,636,198...64,670,019
Ensembl chr16:83,983,626...84,013,436 		JBrowse link
G NELFE negative elongation factor complex member E ISO RGD PMID:19014935 RGD:9693721 NCBI chr 6:31,612,924...31,619,732
Ensembl chr 6:32,499,540...32,506,382 		JBrowse link
G NGF nerve growth factor ISO RGD PMID:17310240 PMID:25062286 RGD:1626216 RGD:401977578 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22033934)
(PMID:18261938)		 Ensembl
MGI		 PMID:18261938 PMID:22033934 GO_REF:0000107 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G NODAL nodal growth differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:66,906,866...66,916,938
Ensembl chr10:69,433,959...69,443,972 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G NOTCH2 notch receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840 		JBrowse link
G NOX4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) UniProt PMID:17942966 MGI:5009390 NCBI chr11:84,330,362...84,496,755 JBrowse link
G NPNT nephronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,365,727...98,445,746
Ensembl chr 4:108,974,971...109,054,671 		JBrowse link
G NPSR1 neuropeptide S receptor 1 ISO RGD PMID:23761908 RGD:9831201 NCBI chr 7:35,274,102...35,494,389
Ensembl chr 7:35,663,335...35,883,988 		JBrowse link
G NPTN neuroplastin ISO RGD PMID:19952283 RGD:2325174 NCBI chr15:52,470,545...52,544,046
Ensembl chr15:71,229,992...71,269,579 		JBrowse link
G NPY neuropeptide Y ISO RGD PMID:21595512 RGD:10448272 NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657 		JBrowse link
G NPY5R neuropeptide Y receptor Y5 ISO RGD PMID:21595512 RGD:10448272 NCBI chr 4:155,603,739...155,612,302 JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 ISO RGD PMID:23554738 RGD:11073697 NCBI chr 6:2,819,422...2,844,765
Ensembl chr 6:2,928,021...2,947,304 		JBrowse link
G NRG1 neuregulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977 		JBrowse link
G NRP1 neuropilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G NRXN1 neurexin 1 involved_in ISO (PMID:26078884) ARUK-UCL PMID:26078884 NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 involved_in
NOT|involved_in		 IEA
ISO		 (PMID:15488758) Ensembl
UniProt		 PMID:15488758 GO_REF:0000107 Ensembl chr 1:136,007,476...136,047,355 JBrowse link
G NTSR2 neurotensin receptor 2 ISO RGD PMID:16564027 RGD:9743898 NCBI chr2A:11,645,312...11,657,377 JBrowse link
G OPRM1 opioid receptor mu 1 involved_in ISO PMID:17384143 UniProt PMID:17384143 RGD:8656005 NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251 		JBrowse link
G P2RY1 purinergic receptor P2Y1 involved_in ISO PMID:20847060 BHF-UCL PMID:20847060 RGD:8554370 NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813 		JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:68,341,722...68,375,923
Ensembl chr11:71,594,250...71,595,236 		JBrowse link
G PDE8A phosphodiesterase 8A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:63,649,336...63,805,613
Ensembl chr15:82,971,986...83,127,957 		JBrowse link
G PDGFA platelet derived growth factor subunit A involved_in ISO (PMID:11788434) UniProt PMID:11788434 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883 		JBrowse link
G PDGFC platelet derived growth factor C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:149,105,330...149,317,254
Ensembl chr 4:160,922,827...161,131,960 		JBrowse link
G PDGFD platelet derived growth factor D involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:98,852,652...99,110,147
Ensembl chr11:102,357,079...102,593,273 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530 		JBrowse link
G PHB1 prohibitin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790 		JBrowse link
G PHB2 prohibitin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053 		JBrowse link
G PLA2G2A phospholipase A2 group IIA involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,930,294...18,934,563
Ensembl chr 1:19,971,084...19,977,627 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,983,104...19,046,834
Ensembl chr 1:20,068,110...20,089,840 		JBrowse link
G PRKCA protein kinase C alpha involved_in ISO PMID:11864993 UniProt PMID:11864993 RGD:8554603 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855 		JBrowse link
G PRKD2 protein kinase D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:43,666,591...43,710,858
Ensembl chr19:52,195,303...52,237,731 		JBrowse link
G PRXL2C peroxiredoxin like 2C involved_in ISO (PMID:29901208) UniProt PMID:29901208 NCBI chr 9:67,737,639...67,751,691 JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:25512490) MGI PMID:25512490 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18827006)
(PMID:24431450)		 TreeGrafter
MGI		 PMID:18827006 PMID:24431450 GO_REF:0000118 NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RAMP3 receptor activity modifying protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:45,871,687...45,898,159
Ensembl chr 7:45,937,607...45,966,041 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family involved_in
acts_upstream_of_or_within		 ISO PMID:17724123
(PMID:23616533)		 UniProt
MGI		 PMID:17724123 PMID:23616533 RGD:8554481 NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family acts_upstream_of_or_within ISO (PMID:23616533) MGI PMID:23616533 NCBI chr12:66,122,212...66,172,450
Ensembl chr12:68,942,053...68,955,649 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:16507992 RGD:11534985 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:16272156), (PMID:23800469)
(MGI:5514088|PMID:23800469)
(MGI:5499726|PMID:16272156)
PMID:17724123		 UniProt PMID:16272156 PMID:17724123 PMID:23800469 MGI:5499726 MGI:5514088 RGD:8554481 NCBI chr 4:151,419,402...151,680,769
Ensembl chr 4:163,316,396...163,487,495 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938)
(PMID:11894098)		 Ensembl
MGI		 PMID:11894098 PMID:18261938 GO_REF:0000107 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268 		JBrowse link
G SAA2 serum amyloid A2 involved_in ISO (PMID:21701568) AgBase PMID:21701568 NCBI chr11:18,280,393...18,283,913 JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,258,376...5,283,747
Ensembl chr17:5,247,307...5,270,817 		JBrowse link
G SEMA7A semaphorin 7A (JohnMiltonHagen blood group) involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:53,351,662...53,376,327
Ensembl chr15:72,972,475...72,996,953 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,725,469...1,738,887
Ensembl chr17:1,618,549...1,631,570 		JBrowse link
G SHC1 SHC adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,310,778...130,323,001
Ensembl chr 1:133,920,532...133,929,008 		JBrowse link
G SLAMF1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:20231852) UniProt PMID:20231852 NCBI chr 1:135,963,748...136,002,982
Ensembl chr 1:139,888,772...139,925,461 		JBrowse link
G SLC30A10 solute carrier family 30 member 10 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:26728129) Ensembl
UniProt		 PMID:26728129 GO_REF:0000107 NCBI chr 1:195,480,707...195,528,243
Ensembl chr 1:200,522,554...200,566,228 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G SSTR4 somatostatin receptor 4 ISO RGD PMID:8175684 RGD:2325010 NCBI chr20:22,982,009...22,986,058
Ensembl chr20:23,333,320...23,334,766 		JBrowse link
G TEK TEK receptor tyrosine kinase involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 (PMID:18425120) Ensembl
GO_Central		 PMID:18425120 GO_REF:0000107 NCBI chr 9:26,955,339...27,077,809
Ensembl chr 9:27,561,421...27,683,572 		JBrowse link
G TFF2 trefoil factor 2 acts_upstream_of_or_within ISO (PMID:19064997) MGI PMID:19064997 NCBI chr21:28,653,077...28,657,709
Ensembl chr21:41,973,111...41,977,227 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973 		JBrowse link
G THPO thrombopoietin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:181,409,038...181,416,986
Ensembl chr 3:189,891,025...189,897,429 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:121,100,558...121,112,844
Ensembl chr11:125,018,064...125,022,309 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:22033934) MGI PMID:22033934 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNFAIP8L3 TNF alpha induced protein 8 like 3 involved_in ISO (MGI:5613301|PMID:25242044) UniProt PMID:25242044 MGI:5613301 NCBI chr15:30,008,024...30,046,021
Ensembl chr15:48,343,714...48,390,020 		JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:55,695,394...55,761,307
Ensembl chr18:59,034,770...59,075,044 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,750,835...23,784,740 JBrowse link
G TPBG trophoblast glycoprotein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22956548)
(PMID:20376365)		 Ensembl
MGI		 PMID:20376365 PMID:22956548 GO_REF:0000107 NCBI chr 6:80,265,172...80,273,022
Ensembl chr 6:83,530,571...83,531,915 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (PMID:23639442)
(PMID:24863063)
(MGI:5287519|PMID:21828096)		 BHF-UCL PMID:21828096 PMID:23639442 PMID:24863063 MGI:5287519 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
G VEGFB vascular endothelial growth factor B involved_in ISO (PMID:18259607) UniProt PMID:18259607 NCBI chr11:59,591,750...59,595,926 JBrowse link
regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in ISO (MGI:5486555|PMID:17086211) UniProt PMID:17086211 MGI:5486555 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732 		JBrowse link
G ARHGEF5 Rho guanine nucleotide exchange factor 5 NOT|involved_in ISO (PMID:15601624) UniProt PMID:15601624 NCBI chr 7:136,069,598...136,094,866
Ensembl chr 7:148,558,803...148,584,078 		JBrowse link
G BMP4 bone morphogenetic protein 4 ISO RGD PMID:19229878 RGD:8885195 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO PMID:11694516 UniProt PMID:11694516 RGD:11041061 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:21277852 RGD:5491003 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220 		JBrowse link
G ECE1 endothelin converting enzyme 1 ISO RGD PMID:21878523 RGD:7243869 NCBI chr 1:20,166,019...20,290,803
Ensembl chr 1:21,206,199...21,278,909 		JBrowse link
G EGFR epidermal growth factor receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615 		JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787 		JBrowse link
G EPHA7 EPH receptor A7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:91,143,240...91,322,040
Ensembl chr 6:94,392,353...94,566,716 		JBrowse link
G EPHB1 EPH receptor B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:131,841,459...132,309,082
Ensembl chr 3:139,313,387...139,776,802 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862 		JBrowse link
G FAM83B family with sequence similarity 83 member B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:54,396,231...54,493,970
Ensembl chr 6:56,033,426...56,128,390 		JBrowse link
G FAM83D family with sequence similarity 83 member D involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:35,251,338...35,278,057
Ensembl chr20:36,357,610...36,384,355 		JBrowse link
G FAM83E family with sequence similarity 83 member E involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:45,602,210...45,615,518 JBrowse link
G FAM83F family with sequence similarity 83 member F involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:20,900,012...20,948,588
Ensembl chr22:38,719,795...38,753,949 		JBrowse link
G FAM83G family with sequence similarity 83 member G involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:32,237,065...32,273,015
Ensembl chr17:37,169,509...37,204,872 		JBrowse link
G FAM83H family with sequence similarity 83 member H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:140,476,051...140,492,613
Ensembl chr 8:143,491,945...143,496,919 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (PMID:16989802) MGI PMID:16989802 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815 		JBrowse link
G FN1 fibronectin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23782834) Ensembl
MGI		 PMID:23782834 GO_REF:0000107 NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (MGI:5009198|PMID:10945608) BHF-UCL PMID:10945608 MGI:5009198 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16271875) Ensembl
MGI		 PMID:16271875 GO_REF:0000107 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G L1CAM L1 cell adhesion molecule ISO RGD PMID:16478533 RGD:11570403 NCBI chr  X:143,412,303...143,437,090
Ensembl chr  X:153,298,690...153,324,228 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO RGD PMID:26581593 RGD:12879823 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
G NEK10 NIMA related kinase 10 involved_in ISO (PMID:20956560) UniProt PMID:20956560 NCBI chr 3:27,002,397...27,257,856
Ensembl chr 3:27,330,021...27,584,340 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16271875) Ensembl
MGI		 PMID:16271875 GO_REF:0000107 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,166,516...51,635,057
Ensembl chr 6:52,435,462...52,903,309 		JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:21917714 RGD:9491825 NCBI chr14:3,737,741...3,746,646
Ensembl chr14:21,836,984...21,846,018 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G RIT2 Ras like without CAAX 2 NOT|involved_in ISO (MGI:2179663|PMID:11877426) ParkinsonsUK-UCL PMID:11877426 MGI:2179663 NCBI chr18:36,008,302...36,381,259
Ensembl chr18:39,557,814...39,930,393 		JBrowse link
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:115,095,753...115,234,525
Ensembl chr 6:119,238,419...119,376,053 		JBrowse link
G RRAS RAS related involved_in ISO (PMID:24705357) UniProt PMID:24705357 NCBI chr19:46,649,892...46,654,754
Ensembl chr19:55,569,749...55,573,721 		JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:33,326,587...33,371,399
Ensembl chr14:51,610,523...51,651,096 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 NOT|involved_in ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:22564263 RGD:9835036 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883 		JBrowse link
G TRAF7 TNF receptor associated factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,013,831...1,036,486
Ensembl chr16:2,266,194...2,279,031 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta involved_in ISO (PMID:31024343) UniProt PMID:31024343 NCBI chr 8:97,560,251...97,595,117
Ensembl chr 8:99,730,393...99,762,990 		JBrowse link
G ZDHHC17 zinc finger DHHC-type palmitoyltransferase 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:74,281,716...74,371,885
Ensembl chr12:77,132,723...77,222,509 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      signal transduction 5399
        intracellular signal transduction 2589
          intracellular signaling cassette 1812
            MAPK cascade 745
              ERK1 and ERK2 cascade 352
                negative regulation of ERK1 and ERK2 cascade 79
                positive regulation of ERK1 and ERK2 cascade 222
                regulation of ERK1 and ERK2 cascade + 325
Path 2
Term Annotations click to browse term
  biological_process 16313
    biological regulation 11327
      regulation of biological process 10982
        signaling 5900
          signal transduction 5399
            intracellular signal transduction 2589
              intracellular signaling cassette 1812
                MAPK cascade 745
                  ERK1 and ERK2 cascade 352
                    negative regulation of ERK1 and ERK2 cascade 79
                    positive regulation of ERK1 and ERK2 cascade 222
                    regulation of ERK1 and ERK2 cascade + 325
paths to the root