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ONTOLOGY REPORT - ANNOTATIONS

Term:ERK1 and ERK2 cascade
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Accession:GO:0070371 term browser browse the term
Definition:An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
Comment:Note that this MAPKKK cascade is commonly referred to as the ERK pathway in the literature, but involves only ERK1 or ERK2 and should not be confused with cascades that involve other ERK kinases.
Synonyms:exact_synonym: ERK1 and ERK2 signaling pathway;   ERK1 and ERK2 signalling pathway;   ERK1/2 cascade;   extracellular signal-regulated kinase 1/2 (ERK1/2) cascade;   extracellular signal-regulated kinase 1/2 cascade
 narrow_synonym: ERK1 cascade;   ERK2 cascade;   MAPK1 cascade;   MAPK3 cascade
 broad_synonym: ERK cascade


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ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of
involved_in		 ISO
IEA		 MGI:104738 (MGI:5449665|PMID:22729085)
GO_REF:0000107		 RGD
Ensembl		 PMID:22729085 GO_REF:0000107 MGI:5449665 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Agt angiotensinogen IDA RGD PMID:21367774 RGD:5129174 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ankrd26 ankyrin repeat domain containing 26 acts_upstream_of ISO MGI:3774418 (MGI:5285770|PMID:21669876) RGD PMID:21669876 MGI:5285770 NCBI chr 4:151,670,604...151,740,032
Ensembl chr 4:151,672,037...151,739,968 		JBrowse link
G Apoa1 apolipoprotein A1 NOT|involved_in ISO (PMID:23726972) RGD PMID:23726972 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Avp arginine vasopressin involved_in ISO (PMID:18402937) RGD PMID:18402937 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of ISO MGI:1857579|MGI:3620008|MGI:3622450|MGI:3711006 (MGI:3047520|PMID:15199148), (MGI:3620005|PMID:16342120), (MGI:3695981|PMID:15784729), (MGI:5473721|PMID:23334952), (MGI:5490391|PMID:23616533) RGD PMID:15199148 PMID:15784729 PMID:16342120 PMID:23334952 PMID:23616533 MGI:3047520 MGI:3620005 MGI:3695981 MGI:5473721 MGI:5490391 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5520006|PMID:23589618)
GO_REF:0000107		 RGD
Ensembl		 PMID:23589618 GO_REF:0000107 MGI:5520006 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G C1ql4 complement C1q like 4 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5527130|PMID:23449976)
GO_REF:0000107		 RGD
Ensembl		 PMID:23449976 GO_REF:0000107 MGI:5527130 NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678 		JBrowse link
G C1qtnf3 C1q and TNF related 3 acts_upstream_of ISO (MGI:4868567|PMID:20952387) RGD PMID:20952387 MGI:4868567 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433 		JBrowse link
G Cckbr cholecystokinin B receptor IMP RGD PMID:17226751 RGD:2311329 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 IGI RGD PMID:12413953 RGD:4145648 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 IGI RGD PMID:12413953 RGD:4145648 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO (MGI:6477849|PMID:32675284) RGD PMID:32675284 MGI:6477849 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:24520418) RGD PMID:24520418 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctsh cathepsin H involved_in ISO
IEA
ISS		 (PMID:21217776)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21217776 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (MGI:4850213|PMID:20929948) RGD PMID:20929948 MGI:4850213 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egf epidermal growth factor involved_in ISO
IEA		 (PMID:16314496)
GO_REF:0000107		 RGD
Ensembl		 PMID:16314496 GO_REF:0000107 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Eno1 enolase 1 involved_in IDA PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Fgf10 fibroblast growth factor 10 involved_in
acts_upstream_of		 ISO (PMID:17959718)
MGI:1345138|MGI:1345139|MGI:1859647|MGI:95523 (MGI:3040788|PMID:15130516), (MGI:3703479|PMID:17202188), (MGI:5052190|PMID:21764747)		 RGD PMID:15130516 PMID:17202188 PMID:17959718 PMID:21764747 MGI:3040788 MGI:3703479 MGI:5052190 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf18 fibroblast growth factor 18 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:2175916|PMID:11741978)
GO_REF:0000107		 RGD
Ensembl		 PMID:11741978 GO_REF:0000107 MGI:2175916 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3701731|PMID:16858399)
GO_REF:0000107		 RGD
Ensembl		 PMID:16858399 GO_REF:0000107 MGI:3701731 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (MGI:5512808|PMID:23523568) RGD PMID:23523568 MGI:5512808 NCBI chr 4:159,914,393...159,922,073
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of ISO MGI:1099809 (MGI:3703479|PMID:17202188) RGD PMID:17202188 MGI:3703479 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (MGI:4437389|PMID:20053668) RGD PMID:20053668 MGI:4437389 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Flcn folliculin acts_upstream_of
involved_in		 ISO
IEA		 MGI:3774414|MGI:4348628 (MGI:3772618|PMID:18182616), (MGI:5050037|PMID:21258407)
GO_REF:0000107		 RGD
Ensembl		 PMID:18182616 PMID:21258407 GO_REF:0000107 MGI:3772618 MGI:5050037 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Grb10 growth factor receptor bound protein 10 involved_in
acts_upstream_of_or_within_negative_effect		 IEA
ISO		 GO_REF:0000107
(MGI:5921469|PMID:26941017)		 Ensembl
RGD		 PMID:26941017 GO_REF:0000107 MGI:5921469 NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Hesx1 HESX homeobox 1 acts_upstream_of_or_within ISO (MGI:6451356|PMID:31761678) RGD PMID:31761678 MGI:6451356 NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:4457445|PMID:20450948), (MGI:86840|PMID:8621713)
GO_REF:0000024
(PMID:19308295)		 Ensembl
RGD
UniProt		 PMID:8621713 PMID:19308295 PMID:20450948 GO_REF:0000024 GO_REF:0000107 MGI:4457445 MGI:86840 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:24508636)
GO_REF:0000107		 RGD
Ensembl		 PMID:24508636 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 acts_upstream_of_or_within ISO (MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:3835718 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (MGI:5284791|PMID:16014375) RGD PMID:16014375 MGI:5284791 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Kars1 lysyl-tRNA synthetase 1 involved_in ISO
IMP		 UniProtKB:Q5XIM7 (PMID:19524539) RGD PMID:19524539 PMID:19524539 RGD:12793003 NCBI chr19:39,957,846...39,976,886
Ensembl chr19:39,957,846...39,977,632 		JBrowse link
G Kdr kinase insert domain receptor involved_in ISO
IEA		 (PMID:24863063)
GO_REF:0000107		 RGD
Ensembl		 PMID:24863063 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1346867 (MGI:5588044|PMID:25100655)		 Ensembl
RGD		 PMID:25100655 GO_REF:0000107 MGI:5588044 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:24375836)
MGI:1346866 (MGI:5588044|PMID:25100655)		 RGD PMID:24375836 PMID:25100655 MGI:5588044 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:19524539
MGI:1346859 (MGI:3828894|PMID:19047410)
(PMID:16314496)		 RGD PMID:16314496 PMID:19047410 PMID:19524539 MGI:3828894, RGD:12793003 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO MGI:1346858 (MGI:3828894|PMID:19047410) RGD PMID:19047410 MGI:3828894 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mir504 microRNA 504 acts_upstream_of_or_within_positive_effect ISO (MGI:5921469|PMID:26941017) RGD PMID:26941017 MGI:5921469 NCBI chr  X:137,318,540...137,318,616
Ensembl chr  X:137,318,540...137,318,616 		JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase involved_in ISO (PMID:12533425) RGD PMID:12533425 NCBI chr 5:16,859,957...16,861,264
Ensembl chr 5:16,859,957...16,861,264 		JBrowse link
G Mt3 metallothionein 3 involved_in ISO
ISS		 (PMID:18554677)
GO_REF:0000024		 RGD
UniProt		 PMID:18554677 GO_REF:0000024 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:15459207) RGD PMID:15459207 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 acts_upstream_of
involved_in		 ISO
IEA		 MGI:4836357 (MGI:5436198|PMID:22503542)
GO_REF:0000107		 RGD
Ensembl		 PMID:22503542 GO_REF:0000107 MGI:5436198 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:10497238 RGD:2304226 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Ptger4 prostaglandin E receptor 4 involved_in IDA PMID:19233324 UniProt PMID:19233324 RGD:8554254 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 acts_upstream_of
involved_in		 ISO
IEA		 MGI:95516 (MGI:3701731|PMID:16858399)
GO_REF:0000107		 RGD
Ensembl		 PMID:16858399 GO_REF:0000107 MGI:3701731 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of
involved_in		 ISO
IEA		 MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:11894098 PMID:18261938 GO_REF:0000107 MGI:2176422 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Smad4 SMAD family member 4 IMP RGD PMID:11401854 RGD:12903275 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285125|PMID:21512138)		 UniProt
RGD		 PMID:21512138 GO_REF:0000024 MGI:5285125 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 acts_upstream_of
involved_in		 ISO
IEA		 MGI:1099809|MGI:1345138 (MGI:5052190|PMID:21764747)
GO_REF:0000107		 RGD
Ensembl		 PMID:21764747 GO_REF:0000107 MGI:5052190 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 acts_upstream_of
involved_in		 ISO
IEA		 MGI:1099809|MGI:1345139 (MGI:5052190|PMID:21764747)
GO_REF:0000107		 RGD
Ensembl		 PMID:21764747 GO_REF:0000107 MGI:5052190 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Tbc1d10c TBC1 domain family, member 10C acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5576870|PMID:23109291)
GO_REF:0000107		 RGD
Ensembl		 PMID:23109291 GO_REF:0000107 MGI:5576870 NCBI chr 1:201,476,258...201,484,876
Ensembl chr 1:201,477,157...201,564,920 		JBrowse link
G Tf transferrin involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of ISO MGI:2674036 (MGI:5299952|PMID:22033934) RGD PMID:22033934 MGI:5299952 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO
IEA		 (MGI:3838421|PMID:19252502)
GO_REF:0000107		 RGD
Ensembl		 PMID:19252502 GO_REF:0000107 MGI:3838421 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in ISO MGI:3771073 (MGI:5314179|PMID:22114204) RGD PMID:22114204 MGI:5314179 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:6109167|PMID:29118970)		 Ensembl
RGD		 PMID:29118970 GO_REF:0000107 MGI:6109167 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25106868)		 UniProt
RGD		 PMID:25106868 GO_REF:0000024 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO (PMID:25106868) RGD PMID:25106868 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
negative regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:104738 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 IMP RGD PMID:20703229 RGD:9685431 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:12070119)		 UniProt
RGD		 PMID:12070119 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Ankrd26 ankyrin repeat domain containing 26 acts_upstream_of_or_within ISO MGI:3774418 (MGI:5285770|PMID:21669876) RGD PMID:21669876 MGI:5285770 NCBI chr 4:151,670,604...151,740,032
Ensembl chr 4:151,672,037...151,739,968 		JBrowse link
G Arrb1 arrestin, beta 1 IMP RGD PMID:19254952 RGD:5509898 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Atf3 activating transcription factor 3 involved_in ISO (MGI:5297260|PMID:22053207) RGD PMID:22053207 MGI:5297260 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within ISO (MGI:5520006|PMID:23589618) RGD PMID:23589618 MGI:5520006 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G C1ql4 complement C1q like 4 acts_upstream_of_or_within ISO (MGI:5527130|PMID:23449976) RGD PMID:23449976 MGI:5527130 NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678 		JBrowse link
G C2h3orf33 similar to human chromosome 3 open reading frame 33 involved_in ISO (PMID:20680465) RGD PMID:20680465 NCBI chr 2:148,376,598...148,404,343
Ensembl chr 2:148,380,581...148,404,387 		JBrowse link
G Cav1 caveolin 1 IDA RGD PMID:20172952 RGD:6849300 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit IMP RGD PMID:20505147 RGD:8549538 NCBI chr 1:156,487,279...156,494,277
Ensembl chr 1:156,487,279...156,491,476 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IMP RGD PMID:20505147 RGD:8549538 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit IMP RGD PMID:20505147 RGD:8549538 NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192 		JBrowse link
G Cnksr3 Cnksr family member 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:4457233|PMID:19567370)		 UniProt
Ensembl
RGD		 PMID:19567370 GO_REF:0000024 GO_REF:0000107 MGI:4457233 NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635 		JBrowse link
G Cryba1 crystallin, beta A1 IMP RGD PMID:21993393 RGD:10059647 NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726 		JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:9325302 RGD:2303720 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IDA PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:19903888)		 UniProt
RGD		 PMID:19903888 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISO
IEA		 (PMID:20551903)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551903 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dmd dystrophin acts_upstream_of_or_within ISO MGI:1856328 (MGI:3028267|PMID:14718391) RGD PMID:14718391 MGI:3028267 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IMP RGD PMID:17437549 RGD:7771545 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in ISO (MGI:5905244|PMID:25772234) RGD PMID:25772234 MGI:5905244 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp26 dual specificity phosphatase 26 involved_in ISO (PMID:16581800) RGD PMID:16581800 NCBI chr16:61,041,784...61,049,319
Ensembl chr16:61,041,792...61,049,051 		JBrowse link
G Dusp29 dual specificity phosphatase 29 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6450308|PMID:32639872)		 UniProt
RGD		 PMID:32639872 GO_REF:0000024 MGI:6450308 NCBI chr15:2,593,473...2,634,019
Ensembl chr15:2,593,578...2,633,503 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11085983)		 RGD PMID:11085983 PMID:21873635 RGD:13792537 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G Dusp4 dual specificity phosphatase 4 involved_in ISO
ISS		 (PMID:7535768)
GO_REF:0000024		 RGD
UniProt		 PMID:7535768 GO_REF:0000024 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp6 dual specificity phosphatase 6 involved_in IDA
ISO
IBA		 (PMID:18771677)
PMID:21873635		 RGD PMID:18771677 PMID:8626780 PMID:21873635 RGD:728656, RGD:13792537 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dusp9 dual specificity phosphatase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821 		JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A IMP RGD PMID:22025682 RGD:10755441 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO (PMID:29093007) RGD PMID:29093007 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (MGI:5905277|PMID:11585923) RGD PMID:11585923 MGI:5905277 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IDA RGD PMID:19204184 RGD:9685562 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) RGD PMID:20551903 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fbln1 fibulin 1 involved_in ISO (PMID:11792823) RGD PMID:11792823 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:3774414|MGI:4348628 (MGI:3772618|PMID:18182616), (MGI:5050037|PMID:21258407)		 UniProt
RGD		 PMID:18182616 PMID:21258407 GO_REF:0000024 MGI:3772618 MGI:5050037 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24337748) RGD PMID:24337748 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA		 (PMID:23840305)
GO_REF:0000107		 RGD
Ensembl		 PMID:23840305 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009411|PMID:16023107)
(PMID:11408560)		 BHF-UCL
RGD		 PMID:11408560 PMID:16023107 GO_REF:0000024 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:96787 (MGI:3640953|PMID:16691571) RGD PMID:16691571 MGI:3640953 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Klf4 Kruppel like factor 4 involved_in IMP PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:96432 (MGI:3640953|PMID:16691571)		 Ensembl
RGD		 PMID:16691571 GO_REF:0000107 MGI:3640953 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lmo3 LIM domain only 3 involved_in ISO (PMID:23823477) RGD PMID:23823477 NCBI chr 4:171,234,686...171,297,677
Ensembl chr 4:171,234,696...171,292,222 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:2687173|PMID:14525964), (MGI:3044099|PMID:14726379)		 UniProt
RGD		 PMID:14525964 PMID:14726379 GO_REF:0000024 MGI:2687173 MGI:3044099 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir200c microRNA 200c acts_upstream_of ISO (PMID:24205206) RGD PMID:24205206 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:20483747) RGD PMID:20483747 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:23333386) RGD PMID:23333386 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir322 microRNA 322 involved_in ISO RNAcentral:URS00000F6E49_9606 (PMID:23263626) RGD PMID:23263626 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir503 microRNA 503 involved_in ISO RNAcentral:URS00000F0F49_9606 (PMID:23263626) RGD PMID:23263626 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Ndrg2 NDRG family member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4835375|PMID:19815093)
GO_REF:0000107		 RGD
Ensembl		 PMID:19815093 GO_REF:0000107 MGI:4835375 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 acts_upstream_of_or_within ISO MGI:4836357 (MGI:5436198|PMID:22503542) RGD PMID:22503542 MGI:5436198 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISO (MGI:5432950|PMID:22763455) RGD PMID:22763455 MGI:5432950 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:24732013) RGD PMID:24732013 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IMP PMID:20819118 UniProt PMID:20819118 RGD:8693633 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:20179103) RGD PMID:20179103 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Psca prostate stem cell antigen involved_in ISO (PMID:25680266) RGD PMID:25680266 NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IBA		 UniProtKB:P97333 (MGI:5490930|PMID:23639442)
PMID:21873635		 RGD PMID:23639442 PMID:21873635 MGI:5490930, RGD:13792537 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:3530208|PMID:15696169)		 UniProt
RGD		 PMID:15696169 PMID:21873635 GO_REF:0000024 MGI:3530208, RGD:13792537 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:P06240 (MGI:3530407|PMID:15661907) RGD PMID:15661907 MGI:3530407 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R involved_in IEA
ISO		 GO_REF:0000107
(PMID:21724833)		 Ensembl
RGD		 PMID:21724833 GO_REF:0000107 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603 		JBrowse link
G Ranbp9 RAN binding protein 9 involved_in ISO (PMID:23118896) RGD PMID:23118896 NCBI chr17:21,220,807...21,303,009
Ensembl chr17:21,220,618...21,303,004 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:95516 (MGI:3701731|PMID:16858399) RGD PMID:16858399 MGI:3701731 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in IDA PMID:19878719 UniProt PMID:19878719 RGD:8553779 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 involved_in ISO (MGI:3041939|PMID:15121846) RGD PMID:15121846 MGI:3041939 NCBI chr  X:76,354,824...76,454,484
Ensembl chr  X:76,353,760...76,454,484 		JBrowse link
G Sema6a semaphorin 6A involved_in ISO (PMID:21536891) RGD PMID:21536891 NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954 		JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Sirt3 sirtuin 3 IMP RGD PMID:23397292 RGD:9586042 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3689643|PMID:16151019)		 Ensembl
RGD		 PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:5766647|PMID:26934179), (MGI:6414698|PMID:29501879) RGD PMID:26934179 PMID:29501879 MGI:5766647 MGI:6414698 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414698|PMID:29501879)		 UniProt
RGD		 PMID:29501879 GO_REF:0000024 MGI:6414698 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within
involved_in		 ISO MGI:1099809|MGI:1345138 (MGI:2154590|PMID:11585837), (MGI:5052190|PMID:21764747)
(MGI:3831894|PMID:19043405), (MGI:6414698|PMID:29501879)		 RGD PMID:11585837 PMID:19043405 PMID:21764747 PMID:29501879 MGI:2154590 MGI:3831894 MGI:5052190 MGI:6414698 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:20489163), (PMID:21536891)
(MGI:5693366|PMID:18508928), (MGI:6414698|PMID:29501879)
MGI:1099809|MGI:1345139 (MGI:2154590|PMID:11585837), (MGI:5052190|PMID:21764747)		 RGD PMID:11585837 PMID:18508928 PMID:20489163 PMID:21536891 PMID:21764747 More... MGI:2154590 MGI:5052190 MGI:5693366 MGI:6414698 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Spry3 sprouty RTK signaling antagonist 3 involved_in ISO (MGI:3695236|PMID:16877379) RGD PMID:16877379 MGI:3695236 NCBI chr12:16,663,188...16,673,124
Ensembl chr12:16,663,389...16,672,531 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004 		JBrowse link
G Synj2bp synaptojanin 2 binding protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:24025447)		 UniProt
RGD		 PMID:24025447 GO_REF:0000024 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406 		JBrowse link
G Tbc1d10c TBC1 domain family, member 10C acts_upstream_of_or_within ISO MGI:1932389 (MGI:5576870|PMID:23109291) RGD PMID:23109291 MGI:5576870 NCBI chr 1:201,476,258...201,484,876
Ensembl chr 1:201,477,157...201,564,920 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19962668)		 Ensembl
RGD		 PMID:19962668 GO_REF:0000107 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4421230|PMID:20051628)		 Ensembl
RGD		 PMID:20051628 GO_REF:0000107 MGI:4421230 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 acts_upstream_of_or_within ISO MGI:1922072 (MGI:5576870|PMID:23109291) RGD PMID:23109291 MGI:5576870 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in IBA
ISO		 PMID:21873635
(PMID:12220502)		 RGD PMID:12220502 PMID:21873635 RGD:13792537 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625 		JBrowse link
G Vrk3 VRK serine/threonine kinase 3 acts_upstream_of_or_within ISO (MGI:3778226|PMID:18035061) RGD PMID:18035061 MGI:3778226 NCBI chr 1:95,243,344...95,270,780
Ensembl chr 1:95,243,364...95,270,780 		JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 involved_in ISO (PMID:17667937) RGD PMID:17667937 NCBI chr17:15,503,672...15,612,479
Ensembl chr17:15,504,261...15,612,479 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3662940|PMID:16908670)		 Alzheimers_University_of_Toronto
RGD		 PMID:16908670 GO_REF:0000024 MGI:3662940 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3814963|PMID:18827006) RGD PMID:18827006 MGI:3814963 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:99511 (MGI:3814963|PMID:18827006) RGD PMID:18827006 MGI:3814963 NCBI chr13:68,673,702...68,839,742
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Ackr3 atypical chemokine receptor 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:22300987)
MGI:1341264|MGI:95294|MGI:98397 (MGI:5507957|PMID:22956548)		 UniProt
RGD		 PMID:22300987 PMID:22956548 GO_REF:0000024 MGI:5507957 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Acta2 actin alpha 2, smooth muscle IMP RGD PMID:24204762 RGD:12879446 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in IMP
ISO		 (PMID:23389627) RGD PMID:23389627 PMID:23688779 RGD:13703057 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 involved_in ISO
IDA
IBA		 (PMID:23800469)
PMID:21873635		 RGD PMID:23800469 PMID:23800469 PMID:21873635 RGD:8554519, RGD:13792537 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO UniProtKB:P05067 (PMID:15457210) RGD PMID:15457210 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akap12 A-kinase anchoring protein 12 IMP RGD PMID:19937403 RGD:14348968 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Alkal1 ALK and LTK ligand 1 involved_in ISO
IBA		 (PMID:26418745)
PMID:21873635		 RGD PMID:26418745 PMID:21873635 RGD:13792537 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948 		JBrowse link
G Alkal2 ALK and LTK ligand 2 involved_in ISO
IBA		 (PMID:26418745)
PMID:21873635		 RGD PMID:26418745 PMID:21873635 RGD:13792537 NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISO
ISS		 (PMID:21831839)
GO_REF:0000024		 RGD
UniProt		 PMID:21831839 GO_REF:0000024 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Angpt1 angiopoietin 1 involved_in ISO
IEA		 (PMID:18425120), (PMID:19615361)
GO_REF:0000107		 RGD
Ensembl		 PMID:18425120 PMID:19615361 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Apela apelin receptor early endogenous ligand involved_in IMP PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chr16:24,694,231...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:28111074)		 Ensembl
RGD		 PMID:28111074 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein involved_in IGI
ISO
IDA		 PMID:11404397
UniProtKB:Q15109 (PMID:15457210)
UniProtKB:F1M670|UniProtKB:P25090|UniProtKB:Q9UEW3 (PMID:18723082), (PMID:20141570)		 RGD PMID:15457210 PMID:18723082 PMID:20141570 PMID:11404397 PMID:11404397 RGD:12790656, RGD:12790656 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arhgap8 Rho GTPase activating protein 8 involved_in ISO (PMID:20179103) RGD PMID:20179103 NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in IMP
IBA
ISO		 PMID:21873635
(PMID:10644702)
(MGI:4453294|PMID:19915011)		 RGD PMID:10644702 PMID:19915011 PMID:19289825 PMID:21873635 MGI:4453294, RGD:5509998, RGD:13792537 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
ISO
IBA		 (PMID:10644702), (PMID:12582207)
PMID:21873635		 RGD PMID:10644702 PMID:12582207 PMID:19171933 PMID:28274926 PMID:19254952 More... RGD:5510006, RGD:13506828, RGD:5509898, RGD:13792537 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C IMP RGD PMID:17845832 RGD:14700553 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 (PMID:19664780), (PMID:22540193)
GO_REF:0000107		 RGD
Ensembl		 PMID:19664780 PMID:22540193 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3820452|PMID:18692041)		 Ensembl
RGD		 PMID:18692041 GO_REF:0000107 MGI:3820452 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmper BMP-binding endothelial regulator involved_in ISO (PMID:18787191) RGD PMID:18787191 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IMP
ISO		 (PMID:22065586)
MGI:1857579|MGI:3620008|MGI:3622450|MGI:3711006 (MGI:3047520|PMID:15199148), (MGI:3620005|PMID:16342120), (MGI:3695981|PMID:15784729), (MGI:3773982|PMID:18228248), (MGI:5436330|PMID:22892241), (MGI:5473721|PMID:23334952), (MGI:5490391|PMID:23616533)		 RGD PMID:15199148 PMID:15784729 PMID:16342120 PMID:18228248 PMID:22065586 More... MGI:3047520 MGI:3620005 MGI:3695981 MGI:3773982 MGI:5436330 MGI:5473721 MGI:5490391, RGD:2315869 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G C1qtnf3 C1q and TNF related 3 acts_upstream_of_or_within ISO (MGI:4868567|PMID:20952387) RGD PMID:20952387 MGI:4868567 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433 		JBrowse link
G C3 complement C3 IDA RGD PMID:18178156 RGD:5129534 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO
ISS		 (PMID:22496247)
GO_REF:0000024		 RGD
UniProt		 PMID:22496247 GO_REF:0000024 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517 		JBrowse link
G Calcr calcitonin receptor involved_in ISO UniProtKB:O60896|UniProtKB:P05067:PRO_0000000092|UniProtKB:P10997:PRO_0000004106 (PMID:22500019) RGD PMID:22500019 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:18385282 RGD:6907067 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5618187|PMID:25267792)		 UniProt
RGD		 PMID:25267792 GO_REF:0000024 MGI:5618187 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casr calcium-sensing receptor IDA RGD PMID:22192592 RGD:7207059 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811 		JBrowse link
G Cavin3 caveolae associated protein 3 acts_upstream_of_or_within ISO MGI:5518819 (MGI:5518817|PMID:24069528) RGD PMID:24069528 MGI:5518817 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO
IBA		 UniProtKB:O00182 (PMID:15778365), (PMID:25754930)
PMID:21873635		 RGD PMID:15778365 PMID:25754930 PMID:21873635 RGD:13792537 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO
IBA		 (PMID:12729902), (PMID:15778365)
PMID:21873635		 RGD PMID:12729902 PMID:15778365 PMID:21873635 RGD:13792537 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in IBA
ISO
ISS		 PMID:21873635
(PMID:21403648)
GO_REF:0000024		 RGD
UniProt		 PMID:21403648 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,381,179...68,385,811
Ensembl chr10:68,380,188...68,384,001 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn2 cellular communication network factor 2 involved_in ISO (PMID:20008146) RGD PMID:20008146 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:123,589,997...123,613,767
Ensembl chr 8:123,589,621...123,612,687 		JBrowse link
G Cd36 CD36 molecule involved_in ISO
IEA		 (MGI:5693361|PMID:21610069)
GO_REF:0000107		 RGD
Ensembl		 PMID:21610069 GO_REF:0000107 MGI:5693361 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd36-ps1 CD36 molecule, pseudogene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,487,837...17,514,900 JBrowse link
G Cd4 Cd4 molecule involved_in IBA
ISO		 PMID:21873635
(PMID:24942581)		 RGD PMID:24942581 PMID:21873635 RGD:13792537 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in ISO
IBA		 (PMID:17045821)
(MGI:3690285|PMID:17045821)
PMID:21873635		 RGD PMID:17045821 PMID:21873635 MGI:3690285, RGD:13792537 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISO
ISS
IBA		 (PMID:12782713), (PMID:17045821), (PMID:24942581)
GO_REF:0000024
PMID:21873635
(MGI:4419085|PMID:12782713)		 RGD
BHF-UCL		 PMID:12782713 PMID:17045821 PMID:24942581 PMID:21873635 GO_REF:0000024 MGI:4419085, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:23412386 RGD:11341713 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chi3l1 chitinase 3 like 1 involved_in ISO
ISS		 (PMID:21385870)
GO_REF:0000024		 RGD
UniProt		 PMID:21385870 GO_REF:0000024 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IMP
IDA
IEA
ISO		 PMID:11404397
PMID:17898229
GO_REF:0000107
UniProtKB:P05067 (MGI:4437154|PMID:20164328), (MGI:5819349|PMID:17898229), (MGI:5825438|PMID:11404397)		 Ensembl
RGD		 PMID:11404397 PMID:17898229 PMID:20164328 PMID:11404397 PMID:17898229 GO_REF:0000107 MGI:4437154 MGI:5819349 MGI:5825438, RGD:12790656, RGD:12050111 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3818804|PMID:17975111)		 UniProt
RGD		 PMID:17975111 GO_REF:0000024 MGI:3818804 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:23959425)
PMID:21873635
MGI:1931805 (MGI:3614590|PMID:16399079)		 RGD PMID:16399079 PMID:23959425 PMID:21873635 MGI:3614590, RGD:13792537 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5294320|PMID:8007983)		 Ensembl
UniProt
RGD		 PMID:8007983 GO_REF:0000024 GO_REF:0000107 MGI:5294320 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 acts_upstream_of_or_within ISO MGI:1341264 (MGI:5507957|PMID:22956548) RGD PMID:22956548 MGI:5507957 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 involved_in ISO
ISS		 (PMID:23115081)
GO_REF:0000024		 RGD
UniProt		 PMID:23115081 GO_REF:0000024 NCBI chr 1:80,984,751...80,996,842
Ensembl chr 1:80,984,964...80,996,726 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 acts_upstream_of_or_within ISO (MGI:4453532|PMID:20376365) RGD PMID:20376365 MGI:4453532 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 IMP RGD PMID:21055410 RGD:5144006 NCBI chr15:48,190,251...48,229,906
Ensembl chr15:48,189,073...48,304,136 		JBrowse link
G Dcc DCC netrin 1 receptor IMP RGD PMID:15811950 RGD:2314384 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:26674152 RGD:11554781 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddt D-dopachrome tautomerase involved_in ISO UniProtKB:P14174 (PMID:21817065) RGD PMID:21817065 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482 		JBrowse link
G Dennd2b DENN domain containing 2B involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:9632734)		 RGD PMID:9632734 PMID:21873635 RGD:13792537 NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680 		JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 involved_in ISO (MGI:5571536|PMID:24746703) RGD PMID:24746703 MGI:5571536 NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449 		JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18809670 RGD:2311559 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dstyk dual serine/threonine and tyrosine protein kinase involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:23862974)		 UniProt
RGD		 PMID:23862974 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269 		JBrowse link
G Dusp15 dual specificity phosphatase 15 involved_in IMP PMID:27891578 UniProt PMID:27891578 RGD:12903239 NCBI chr 3:141,408,495...141,419,137
Ensembl chr 3:141,408,498...141,418,999 		JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:16543720 RGD:4892323 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Egf epidermal growth factor IDA RGD PMID:17310240 RGD:1626216 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:20551055), (PMID:21673316) RGD PMID:20551055 PMID:21673316 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epo erythropoietin IMP RGD PMID:21749867 RGD:10400910 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Epor erythropoietin receptor IMP RGD PMID:21749867 RGD:10400910 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISO
ISS		 (PMID:10348342)
GO_REF:0000024		 RGD
UniProt		 PMID:10348342 GO_REF:0000024 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Esr1 estrogen receptor 1 IDA RGD PMID:17928626 RGD:5128669 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 IDA
IMP		 RGD PMID:17928626 PMID:24440742 RGD:5128669, RGD:10045880 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5285163|PMID:20215560)		 UniProt
Ensembl
RGD		 PMID:20215560 GO_REF:0000024 GO_REF:0000107 MGI:5285163 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS		 (PMID:10725339)
(MGI:5285163|PMID:20215560)
GO_REF:0000024		 RGD
UniProt		 PMID:10725339 PMID:20215560 GO_REF:0000024 MGI:5285163 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:24226523) RGD PMID:24226523 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3582120|PMID:15774482)		 UniProt
RGD		 PMID:15774482 GO_REF:0000024 MGI:3582120 NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA		 (PMID:10903502), (PMID:19193866)
PMID:21873635		 RGD PMID:10903502 PMID:19193866 PMID:21873635 RGD:13792537 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:10903502), (PMID:19193866) RGD PMID:10903502 PMID:19193866 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO
ISS		 (PMID:18441324)
GO_REF:0000024		 RGD
UniProt		 PMID:18441324 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1345138|MGI:1345139|MGI:1859647|MGI:95523 (MGI:3040788|PMID:15130516), (MGI:3703479|PMID:17202188), (MGI:5052190|PMID:21764747)
PMID:21873635		 RGD PMID:15130516 PMID:17202188 PMID:21764747 PMID:21873635 MGI:3040788 MGI:3703479 MGI:5052190, RGD:13792537 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2175916|PMID:11741978)		 Ensembl
RGD		 PMID:11741978 GO_REF:0000107 MGI:2175916 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf19 fibroblast growth factor 19 involved_in ISO (PMID:17623664), (PMID:19085950) RGD PMID:17623664 PMID:19085950 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in
acts_upstream_of_or_within		 IDA
ISO		 (PMID:17167778)
(MGI:6414698|PMID:29501879)
(MGI:3701731|PMID:16858399)		 RGD PMID:16858399 PMID:17167778 PMID:29501879 PMID:19952283 MGI:3701731 MGI:6414698, RGD:2325174 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf20 fibroblast growth factor 20 acts_upstream_of_or_within IDA PMID:12704805 MGI PMID:12704805 RGD:8553960 NCBI chr16:52,030,853...52,037,612
Ensembl chr16:52,010,194...52,038,204 		JBrowse link
G Fgf21 fibroblast growth factor 21 involved_in ISO (PMID:17623664) RGD PMID:17623664 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (MGI:3696596|PMID:17086194) RGD PMID:17086194 MGI:3696596 NCBI chr 4:159,914,393...159,922,073
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Fgf4 fibroblast growth factor 4 involved_in ISO (PMID:17167778) RGD PMID:17167778 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:99511 (MGI:5545830|PMID:24431450) RGD PMID:24431450 MGI:5545830 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 involved_in ISO (MGI:4949582|PMID:20851768) RGD PMID:20851768 MGI:4949582 NCBI chr 1:234,644,023...234,646,028
Ensembl chr 1:234,644,019...234,646,547 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:1099809 (MGI:3703479|PMID:17202188) RGD PMID:17202188 MGI:3703479 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (PMID:11294897) RGD PMID:11294897 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in ISO
IBA
ISS		 (PMID:21653700)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:21653700 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502), (PMID:19193866) RGD PMID:10903502 PMID:19193866 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 involved_in ISO
IEA		 (PMID:11532940)
GO_REF:0000107		 RGD
Ensembl		 PMID:11532940 GO_REF:0000107 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in ISO UniProtKB:P05067:PRO_0000000092|UniProtKB:Q9UEW3 (PMID:20141570) RGD PMID:20141570 NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Fshr follicle stimulating hormone receptor involved_in ISO
ISS		 (PMID:24058690)
GO_REF:0000024		 RGD
UniProt		 PMID:24058690 GO_REF:0000024 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 involved_in ISO (PMID:19509291) RGD PMID:19509291 NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,423,882...12,585,345 		JBrowse link
G Gas6 growth arrest specific 6 acts_upstream_of_or_within ISO (PMID:15184064) RGD PMID:15184064 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:5780531 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gcg glucagon involved_in IEA
ISO		 GO_REF:0000107
(PMID:25050009)
(MGI:4453294|PMID:19915011)		 Ensembl
RGD		 PMID:19915011 PMID:25050009 GO_REF:0000107 MGI:4453294 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 involved_in ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)		 RGD PMID:21750175 MGI:5545971 NCBI chr17:23,796,859...23,901,625
NCBI chr17:23,866,602...23,868,691
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Glipr2 GLI pathogenesis-related 2 involved_in ISO (PMID:23516513) RGD PMID:23516513 NCBI chr 5:58,170,417...58,200,947
Ensembl chr 5:58,170,425...58,202,272 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11495629 RGD:728462 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 IMP RGD PMID:28543567 RGD:14700993 NCBI chr 9:75,862,151...75,863,140
Ensembl chr 9:75,860,677...75,863,168 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA
IEA
ISO
IMP		 GO_REF:0000107
PMID:23907461
(PMID:20551055), (PMID:21427217)
PMID:23283935
(MGI:5141337|PMID:21673097), (MGI:5512928|PMID:23545157)		 Ensembl
RGD		 PMID:20551055 PMID:21427217 PMID:21673097 PMID:23545157 PMID:19717735 More... GO_REF:0000107 MGI:5141337 MGI:5512928, RGD:4892081, RGD:4892084, RGD:8553942, RGD:8553898, RGD:4892081 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (MGI:3768878|PMID:18036345) RGD PMID:18036345 MGI:3768878 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21673108), (PMID:25297897)		 UniProt
RGD		 PMID:21673108 PMID:25297897 GO_REF:0000024 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559 		JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in ISO (PMID:19805329) RGD PMID:19805329 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24161931)		 Ensembl
RGD		 PMID:24161931 GO_REF:0000107 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:3763563|PMID:18006747) RGD PMID:18006747 MGI:3763563 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hcrtr1 hypocretin receptor 1 acts_upstream_of_or_within ISO (MGI:5303025|PMID:22028875) RGD PMID:22028875 MGI:5303025 NCBI chr 5:142,477,214...142,486,674
Ensembl chr 5:142,477,214...142,486,674 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22370717)
(MGI:3760906|PMID:16365390)		 RGD PMID:16365390 PMID:22370717 MGI:3760906 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:17161379 RGD:5508698 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in IMP
ISO		 (PMID:22065586) RGD PMID:22065586 PMID:18163378 RGD:2314843 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in ISO (PMID:19057895) RGD PMID:19057895 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO
IEA
ISS		 (PMID:19057895)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19057895 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in ISO (PMID:19057895) RGD PMID:19057895 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Iapp islet amyloid polypeptide involved_in ISO ComplexPortal:CPX-3187|UniProtKB:O60896|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:19578119)
GO_REF:0000107		 RGD
Ensembl		 PMID:19578119 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:16595703 RGD:2311095 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 IDA Phosphorylation of STAT3, ERK1/2 RGD PMID:19061939 PMID:20227492 RGD:2306937, RGD:5128677 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A IDA RGD PMID:27477354 RGD:151665478 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Ins2 insulin 2 acts_upstream_of_or_within ISO (MGI:2387283|PMID:12059784) RGD PMID:12059784 MGI:2387283 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17620283 RGD:4892659 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:2673694 (MGI:5608927|PMID:25224220) RGD PMID:25224220 MGI:5608927 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kdr kinase insert domain receptor involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:15215251)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15215251 GO_REF:0000024 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lgals9 galectin 9 involved_in ISO UniProtKB:Q99731 (PMID:24465902), (PMID:25754930) RGD PMID:24465902 PMID:25754930 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lrp1 LDL receptor related protein 1 IMP RGD PMID:24865476 RGD:13800516 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24375836)		 Ensembl
RGD		 PMID:24375836 GO_REF:0000107 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
ISS		 (PMID:28111074)
GO_REF:0000024		 RGD
UniProt		 PMID:28111074 GO_REF:0000024 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28111074)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28111074 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:19664780) RGD PMID:19664780 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Marco macrophage receptor with collagenous structure involved_in IGI PMID:20141570 ARUK-UCL PMID:20141570 RGD:12907556 NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:23327923) RGD PMID:23327923 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO UniProtKB:P30046 (PMID:12782713), (PMID:17045821), (PMID:21817065)
(MGI:3690285|PMID:17045821), (MGI:4437204|PMID:10364264)		 RGD PMID:10364264 PMID:12782713 PMID:17045821 PMID:21817065 MGI:3690285 MGI:4437204 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23239100) RGD PMID:23239100 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir23a microRNA 23a involved_in ISO RNAcentral:URS0000183BED_9606 (PMID:21536891) RGD PMID:21536891 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mir27a microRNA 27a involved_in ISO RNAcentral:URS000059311D_9606 (PMID:21536891) RGD PMID:21536891 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b involved_in ISO RNAcentral:URS00003B95DA_9606 (PMID:21536891) RGD PMID:21536891 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mirlet7b microRNA let-7b involved_in ISO (PMID:26296645) RGD PMID:26296645 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5299282|PMID:21726645)
(PMID:18295594)
PMID:21873635		 UniProt
RGD		 PMID:18295594 PMID:21726645 PMID:21873635 GO_REF:0000024 MGI:5299282, RGD:13792537 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog involved_in ISO (PMID:24681962) RGD PMID:24681962 NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:23354122 RGD:12798521 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Ndrg4 NDRG family member 4 involved_in IBA
IEA
ISO
IDA		 PMID:21873635
GO_REF:0000107
(PMID:12755708)
PMID:16408304		 Ensembl
RGD		 PMID:12755708 PMID:21873635 PMID:16408304 GO_REF:0000107, RGD:13792537, RGD:10047195 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA		 (PMID:19694902)
GO_REF:0000107		 RGD
Ensembl		 PMID:19694902 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684 		JBrowse link
G Nelfe negative elongation factor complex member E IMP RGD PMID:19014935 RGD:9693721 NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355 		JBrowse link
G Ngf nerve growth factor IDA RGD PMID:17310240 RGD:1626216 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO MGI:3529594 (MGI:3775161|PMID:18261938), (MGI:5299952|PMID:22033934)
(MGI:4946442|PMID:21156799)		 RGD PMID:18261938 PMID:21156799 PMID:22033934 MGI:3775161 MGI:4946442 MGI:5299952 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO (PMID:21116837) RGD PMID:21116837 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:11306509) RGD PMID:11306509 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11306509)		 Ensembl
RGD		 PMID:11306509 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) RGD PMID:17942966 MGI:5009390 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Npnt nephronectin involved_in ISO (MGI:4414689|PMID:19944102) RGD PMID:19944102 MGI:4414689 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Npsr1 neuropeptide S receptor 1 IMP RGD PMID:23761908 RGD:9831201 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
G Nptn neuroplastin IDA RGD PMID:19952283 RGD:2325174 NCBI chr 8:58,996,876...59,063,402
Ensembl chr 8:58,996,887...59,063,401 		JBrowse link
G Npy neuropeptide Y IDA RGD PMID:21595512 RGD:10448272 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 IMP RGD PMID:21595512 RGD:10448272 NCBI chr16:23,055,427...23,063,384
Ensembl chr16:23,055,427...23,063,382 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 IMP RGD PMID:23554738 RGD:11073697 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
IEA
ISS		 (PMID:20682778)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20682778 GO_REF:0000024 GO_REF:0000107 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5490930|PMID:23639442) RGD PMID:23639442 MGI:5490930 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:26078884) RGD PMID:26078884 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in
NOT|involved_in		 ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:15488758)		 UniProt
RGD		 PMID:15488758 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Ntsr2 neurotensin receptor 2 IDA RGD PMID:16564027 RGD:9743898 NCBI chr 6:39,424,297...39,431,015
Ensembl chr 6:39,424,324...39,431,014 		JBrowse link
G Olr35 olfactory receptor 35 involved_in ISO (PMID:24999593) RGD PMID:24999593 NCBI chr 1:153,994,678...154,043,281
Ensembl chr 1:154,041,306...154,043,257 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IDA PMID:17384143 UniProt PMID:17384143 RGD:8656005 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IDA PMID:20847060 BHF-UCL PMID:20847060 RGD:8554370 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Pde8a phosphodiesterase 8A involved_in IBA
ISO		 PMID:21873635
(MGI:5484722|PMID:23509299)
(PMID:23509299)		 RGD PMID:23509299 PMID:21873635 MGI:5484722, RGD:13792537 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in IBA
ISO
ISS		 PMID:21873635
(PMID:11788434)
GO_REF:0000024		 RGD
UniProt		 PMID:11788434 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
ISO
IBA
ISS		 GO_REF:0000107
(PMID:11788434), (PMID:16530387), (PMID:17942966)
PMID:21873635
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:11788434 PMID:16530387 PMID:17942966 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfc platelet derived growth factor C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Pdgfd platelet derived growth factor D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO
ISS
IEA		 (PMID:10734113)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:10734113 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO
ISS		 (PMID:21679854)
GO_REF:0000024
(MGI:2680741|PMID:14624252), (MGI:5009390|PMID:17942966)		 RGD
UniProt		 PMID:14624252 PMID:17942966 PMID:21679854 GO_REF:0000024 MGI:2680741 MGI:5009390 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:22417827) RGD PMID:22417827 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO
IEA		 (PMID:22417827)
GO_REF:0000107		 RGD
Ensembl		 PMID:22417827 GO_REF:0000107 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in ISO (PMID:22837859) RGD PMID:22837859 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISO (PMID:22837859) RGD PMID:22837859 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Prkca protein kinase C, alpha involved_in IMP PMID:11864993 UniProt PMID:11864993 RGD:8554603 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcz protein kinase C, zeta involved_in IMP
ISO
ISS		 PMID:8557035
(PMID:11035106)
GO_REF:0000024		 RGD
UniProt		 PMID:11035106 PMID:8557035 GO_REF:0000024, RGD:8554313 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5306299|PMID:17226786)		 UniProt
RGD		 PMID:17226786 GO_REF:0000024 MGI:5306299 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Prxl2c peroxiredoxin like 2C involved_in ISO (PMID:29901208) RGD PMID:29901208 NCBI chr17:812,199...844,075
Ensembl chr17:812,213...844,075 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (MGI:5610055|PMID:25512490) RGD PMID:25512490 MGI:5610055 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO
ISS		 (PMID:7544443)
GO_REF:0000024		 RGD
UniProt		 PMID:7544443 GO_REF:0000024 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA		 GO_REF:0000024
(PMID:28074573)
MGI:87860|MGI:99604 (MGI:3814963|PMID:18827006), (MGI:5545830|PMID:24431450)
PMID:21873635		 UniProt
RGD		 PMID:18827006 PMID:24431450 PMID:28074573 PMID:21873635 GO_REF:0000024 MGI:3814963 MGI:5545830, RGD:13792537 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in IBA
ISO		 PMID:21873635
(MGI:5640942|PMID:23991106)
(PMID:23991106)		 RGD PMID:23991106 PMID:21873635 MGI:5640942, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:P05480 (MGI:3530407|PMID:15661907) RGD PMID:15661907 MGI:3530407 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:21487011)
(MGI:5448518|PMID:21487011)		 RGD PMID:21487011 MGI:5448518 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P10997:PRO_0000004106|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:17724123
MGI:894315 (MGI:5490391|PMID:23616533)		 RGD PMID:23616533 PMID:17724123 MGI:5490391, RGD:8554481 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family acts_upstream_of_or_within ISO MGI:97852 (MGI:5490391|PMID:23616533) RGD PMID:23616533 MGI:5490391 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:16507992 RGD:11534985 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in IMP
IBA
ISO
ISS		 PMID:17724123
PMID:21873635
(MGI:5499726|PMID:16272156), (MGI:5514088|PMID:23800469)
GO_REF:0000024
(PMID:16272156), (PMID:23800469)		 RGD
UniProt		 PMID:16272156 PMID:23800469 PMID:17724123 PMID:21873635 GO_REF:0000024 MGI:5499726 MGI:5514088, RGD:8554481, RGD:13792537 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rara retinoic acid receptor, alpha involved_in IMP PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) RGD PMID:19933860 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G RGD1565355 similar to fatty acid translocase/CD36 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938) RGD PMID:11894098 PMID:18261938 MGI:2176422 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:21930792)
(MGI:5300118|PMID:21930792)		 RGD PMID:21930792 MGI:5300118 NCBI chr10:55,507,593...55,528,288
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in ISO
IBA		 (PMID:12879062)
PMID:21873635
(MGI:3710037|PMID:17377534)		 RGD PMID:12879062 PMID:17377534 PMID:21873635 MGI:3710037, RGD:13792537 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:20008146) RGD PMID:20008146 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Shc1 SHC adaptor protein 1 involved_in ISO
IEA		 (PMID:20624904)
GO_REF:0000107		 RGD
Ensembl		 PMID:20624904 GO_REF:0000107 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:20231852) RGD PMID:20231852 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 involved_in ISO (PMID:26728129) RGD PMID:26728129 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:18070883) RGD PMID:18070883 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP
ISO		 PMID:16530387
(MGI:3690285|PMID:17045821)		 RGD PMID:17045821 PMID:16530387 MGI:3690285, RGD:8553998 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689 		JBrowse link
G Tek TEK receptor tyrosine kinase involved_in ISO (PMID:18425120), (PMID:19615361) RGD PMID:18425120 PMID:19615361 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tff2 trefoil factor 2 acts_upstream_of_or_within ISO UniProtKB:P61072 (MGI:3841526|PMID:19064997) RGD PMID:19064997 MGI:3841526 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:25310401)
GO_REF:0000024		 RGD
UniProt		 PMID:25310401 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thpo thrombopoietin involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5314162|PMID:22128142)
PMID:21873635		 UniProt
RGD		 PMID:22128142 PMID:21873635 GO_REF:0000024 MGI:5314162, RGD:13792537 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) RGD PMID:11544529 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2674036 (MGI:5299952|PMID:22033934) RGD PMID:22033934 MGI:5299952 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3775161|PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfaip8l3 TNF alpha induced protein 8 like 3 involved_in ISO (MGI:5613301|PMID:25242044) RGD PMID:25242044 MGI:5613301 NCBI chr 8:54,413,503...54,455,648
Ensembl chr 8:54,414,457...54,500,079 		JBrowse link
G Tpbg trophoblast glycoprotein acts_upstream_of_or_within ISO MGI:103556|MGI:109563 (MGI:4453532|PMID:20376365), (MGI:5507957|PMID:22956548) RGD PMID:20376365 PMID:22956548 MGI:4453532 MGI:5507957 NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IBA
ISO		 PMID:21873635
(MGI:6294162|PMID:28592261)
(PMID:11602640), (PMID:27995897)		 RGD PMID:11602640 PMID:27995897 PMID:28592261 PMID:21873635 MGI:6294162, RGD:13792537 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:5440106 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:23639442)
(MGI:5287519|PMID:21828096)		 RGD PMID:21828096 PMID:23639442 MGI:5287519 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfb vascular endothelial growth factor B involved_in ISO (PMID:18259607) RGD PMID:18259607 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf11a TNF receptor superfamily member 11A involved_in ISO (PMID:18606301) RGD PMID:18606301 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO
IEA		 (PMID:18606301)
GO_REF:0000107		 RGD
Ensembl		 PMID:18606301 GO_REF:0000107 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in ISO (MGI:5486555|PMID:17086211) RGD PMID:17086211 MGI:5486555 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Arhgef5 Rho guanine nucleotide exchange factor 5 NOT|involved_in ISO (PMID:15601624) RGD PMID:15601624 NCBI chr 4:72,087,205...72,112,316
Ensembl chr 4:72,087,247...72,111,254 		JBrowse link
G Bmp4 bone morphogenetic protein 4 IDA RGD PMID:19229878 RGD:8885195 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) RGD PMID:20675382 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IDA PMID:11694516 UniProt PMID:11694516 RGD:11041061 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:21277852 RGD:5491003 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:21878523 RGD:7243869 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:20861311) RGD PMID:20861311 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Epha7 Eph receptor A7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17726105)		 UniProt
RGD		 PMID:17726105 GO_REF:0000024 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
G Ephb1 Eph receptor B1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12925710), (PMID:18034775)		 UniProt
RGD		 PMID:12925710 PMID:18034775 GO_REF:0000024 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in ISO
ISS		 (PMID:16314522)
GO_REF:0000024		 RGD
UniProt		 PMID:16314522 GO_REF:0000024 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Fam83d family with sequence similarity 83, member D involved_in IBA
ISO		 PMID:21873635
(PMID:24736947), (PMID:25646692)		 RGD PMID:24736947 PMID:25646692 PMID:21873635 RGD:13792537 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:3629660 (MGI:3688953|PMID:16989802) RGD PMID:16989802 MGI:3688953 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fn1 fibronectin 1 involved_in ISO
IEA		 (PMID:11792823)
GO_REF:0000107		 RGD
Ensembl		 PMID:11792823 GO_REF:0000107 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO MGI:3768913 (MGI:5528616|PMID:23782834) RGD PMID:23782834 MGI:5528616 NCBI chr 7:52,711,255...52,792,758
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009198|PMID:10945608)		 BHF-UCL
RGD		 PMID:10945608 GO_REF:0000024 MGI:5009198 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:25204733) RGD PMID:25204733 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G L1cam L1 cell adhesion molecule IDA RGD PMID:16478533 RGD:11570403 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:894972|PMID:9252121)		 UniProt
RGD		 PMID:9252121 GO_REF:0000024 MGI:894972 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IDA RGD PMID:26581593 RGD:12879823 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Nek10 NIMA-related kinase 10 involved_in ISO (PMID:20956560) RGD PMID:20956560 NCBI chr15:10,387,063...10,564,177
Ensembl chr15:10,381,140...10,559,722 		JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in ISO (PMID:17669261) RGD PMID:17669261 NCBI chr 9:22,547,396...23,037,443
Ensembl chr 9:22,549,513...23,037,381 		JBrowse link
G Prmt5 protein arginine methyltransferase 5 IMP RGD PMID:21917714 RGD:9491825 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in ISO
IEA
ISS		 (PMID:11266449)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11266449 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:23908768) RGD PMID:23908768 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Rit2 Ras-like without CAAX 2 NOT|involved_in ISO (MGI:2179663|PMID:11877426) RGD PMID:11877426 MGI:2179663 NCBI chr18:22,565,403...22,921,648
Ensembl chr18:22,565,404...22,921,648 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:1930880|PMID:11266449)		 UniProt
RGD		 PMID:11266449 GO_REF:0000024 MGI:1930880 NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865 		JBrowse link
G Rras RAS related involved_in ISO (PMID:24705357) RGD PMID:24705357 NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357 		JBrowse link
G Styx serine/threonine/tyrosine interacting protein involved_in ISO
IBA		 (PMID:23847209)
PMID:21873635		 RGD PMID:23847209 PMID:21873635 RGD:13792537 NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4414596|PMID:19797524)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19797524 GO_REF:0000024 GO_REF:0000107 MGI:4414596 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 NOT|involved_in ISO (MGI:2663364|PMID:12773577) RGD PMID:12773577 MGI:2663364 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:22564263 RGD:9835036 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO (PMID:29961569) RGD PMID:29961569 NCBI chr10:13,533,570...13,552,290
Ensembl chr10:13,533,570...13,552,203 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta involved_in ISO
IEA
ISS		 (PMID:31024343)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31024343 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
G Zdhhc17 zinc finger DHHC-type palmitoyltransferase 17 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5775247|PMID:26232532)		 UniProt
RGD		 PMID:26232532 GO_REF:0000024 MGI:5775247 NCBI chr 7:46,369,963...46,433,691
Ensembl chr 7:46,369,988...46,433,764 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18872
    signaling 7397
      signal transduction 6836
        intracellular signal transduction 2675
          MAPK cascade 852
            ERK1 and ERK2 cascade 378
              negative regulation of ERK1 and ERK2 cascade 88
              positive regulation of ERK1 and ERK2 cascade + 248
              regulation of ERK1 and ERK2 cascade + 351
Path 2
Term Annotations click to browse term
  biological_process 18872
    biological regulation 13378
      regulation of biological process 12642
        regulation of cellular process 11957
          signal transduction 6836
            intracellular signal transduction 2675
              MAPK cascade 852
                ERK1 and ERK2 cascade 378
                  negative regulation of ERK1 and ERK2 cascade 88
                  positive regulation of ERK1 and ERK2 cascade + 248
                  regulation of ERK1 and ERK2 cascade + 351
paths to the root