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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of stress-activated protein kinase signaling cascade
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Accession:GO:0070302 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.
Synonyms:exact_synonym: regulation of SAPK signaling pathway;   regulation of stress-activated protein kinase signaling pathway;   regulation of stress-activated protein kinase signalling pathway


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regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3789238|PMID:16079796) Ensembl
MGI		 PMID:16079796 GO_REF:0000107 MGI:3789238 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160 		JBrowse link
negative regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:16,938,279...16,971,200
Ensembl chr38:16,939,556...16,971,200 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:17064355 RGD:2298577 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:3693042|PMID:17081782) MGI PMID:17081782 MGI:3693042 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175 		JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:33,950,016...33,959,671
Ensembl chr 8:33,949,926...33,958,449 		JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3051749|PMID:15306813) MGI
Ensembl		 PMID:15306813 GO_REF:0000107 MGI:3051749 NCBI chr38:16,196,354...16,233,640
Ensembl chr38:16,196,635...16,231,315 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr36:26,095,436...26,111,700
Ensembl chr36:26,095,463...26,111,774 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:19,518,302...19,531,000
Ensembl chr 9:19,518,746...19,527,624 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in ISO (PMID:19781631) UniProt PMID:19781631 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G FKTN fukutin involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr11:61,394,002...61,462,056
Ensembl chr11:61,405,034...61,461,396 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:32,273,169...32,275,915
Ensembl chr 5:32,273,173...32,275,580 		JBrowse link
G HDAC3 histone deacetylase 3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:36,583,283...36,598,121
Ensembl chr 2:36,583,283...36,597,682 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in ISO (MGI:3774677|PMID:18246070) BHF-UCL PMID:18246070 MGI:3774677 NCBI chr24:23,476,619...23,630,574
Ensembl chr24:23,476,736...23,627,469 		JBrowse link
G KLHL31 kelch like family member 31 involved_in ISO (PMID:18719355) UniProt PMID:18719355 NCBI chr12:21,153,843...21,201,345
Ensembl chr12:21,156,440...21,160,527 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 ISO RGD PMID:12064607 RGD:1299562 NCBI chr18:43,517,186...43,522,603
Ensembl chr18:43,517,677...43,526,379 		JBrowse link
G MARVELD3 MARVEL domain containing 3 acts_upstream_of_or_within ISO (PMID:24567356) MGI PMID:24567356 NCBI chr 5:77,412,353...77,421,032
Ensembl chr 5:77,412,101...77,425,578 		JBrowse link
G MECOM MDS1 and EVI1 complex locus involved_in ISO (PMID:10856240) UniProt PMID:10856240 NCBI chr34:33,747,495...34,299,389
Ensembl chr34:33,748,843...34,299,276 		JBrowse link
G MEN1 menin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,346,747...52,352,884
Ensembl chr18:52,346,933...52,353,340 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:39,687,530...39,837,003
Ensembl chr 5:39,687,543...39,836,464 		JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5308511|PMID:22073305) Ensembl
MGI		 PMID:22073305 GO_REF:0000107 MGI:5308511 NCBI chr 9:46,648,057...46,731,259
Ensembl chr 9:46,648,052...46,771,400 		JBrowse link
G PER1 period circadian regulator 1 involved_in ISO PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr 5:32,957,517...32,972,368
Ensembl chr 5:32,957,127...32,968,465 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G SFRP4 secreted frizzled related protein 4 ISO RGD PMID:18567805 RGD:4107045 NCBI chr18:12,018,049...12,028,123
Ensembl chr18:12,017,978...12,027,788 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in ISO PMID:22128169 UniProt PMID:22128169 RGD:13673844 NCBI chr 2:40,380,313...40,514,211
Ensembl chr 2:40,380,218...40,510,853 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr24:19,094,930...19,136,655 JBrowse link
G TAOK3 TAO kinase 3 involved_in ISO (PMID:10559204) HGNC-UCL PMID:10559204 NCBI chr26:14,534,083...14,712,779
Ensembl chr26:14,534,901...14,631,899 		JBrowse link
G ZMYND11 zinc finger MYND-type containing 11 involved_in ISO (PMID:20732415) UniProt PMID:20732415 NCBI chr 2:34,492,283...34,614,152
Ensembl chr 2:34,493,994...34,570,523 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3799599|PMID:17681137)
(PMID:17681137)		 MGI
Ensembl
Ensembl		 PMID:17681137 GO_REF:0000107 MGI:3799599 NCBI chr38:16,938,279...16,971,200
Ensembl chr38:16,939,556...16,971,200 		JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:50,156,089...50,168,379
Ensembl chr11:50,156,089...50,167,536 		JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (MGI:3051749|PMID:15306813)
(PMID:21873635)		 MGI
Ensembl
GO_Central		 PMID:15306813 PMID:21873635 GO_REF:0000107 MGI:3051749 NCBI chr38:16,196,354...16,233,640
Ensembl chr38:16,196,635...16,231,315 		JBrowse link
G DUSP16 dual specificity phosphatase 16 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr27:33,728,209...33,831,258
Ensembl chr27:33,789,557...33,832,075 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr36:26,095,436...26,111,700
Ensembl chr36:26,095,463...26,111,774 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664)
(MGI:3721484|PMID:12646564)
(MGI:5009198|PMID:10945608), (MGI:5009411|PMID:16023107)		 BHF-UCL PMID:10945608 PMID:12646564 PMID:16023107 PMID:16636664 MGI:3721484 MGI:5009198 MGI:5009411 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G HIPK3 homeodomain interacting protein kinase 3 involved_in ISO (MGI:1913166|PMID:11034606) UniProt PMID:11034606 MGI:1913166 NCBI chr18:34,305,208...34,397,593
Ensembl chr18:34,308,584...34,397,511 		JBrowse link
G LOC119863874 DnaJ heat shock protein family (Hsp40) member A1 involved_in IEA Ensembl GO_REF:0000107
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISO PMID:21076496 RGD
UniProt		 PMID:12064607 PMID:21076496 RGD:1299562 RGD:13673827 NCBI chr18:43,517,186...43,522,603
Ensembl chr18:43,517,677...43,526,379 		JBrowse link
G NPPA natriuretic peptide A involved_in ISO (PMID:22399583) UniProt PMID:22399583 NCBI chr 2:84,406,317...84,408,115
Ensembl chr 2:84,396,073...84,408,385 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G SFRP1 secreted frizzled related protein 1 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3839161|PMID:19300477) Ensembl
MGI
Ensembl		 PMID:19300477 GO_REF:0000107 MGI:3839161 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SFRP5 secreted frizzled related protein 5 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr28:10,994,180...10,999,552
Ensembl chr28:10,993,930...10,999,564 		JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (MGI:3574697|PMID:15483136) MGI PMID:15483136 MGI:3574697 NCBI chr 5:58,194,385...58,241,159
Ensembl chr 5:58,187,826...58,240,839 		JBrowse link
negative regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYLD CYLD lysine 63 deubiquitinase involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr33:30,016,323...30,253,180
Ensembl chr33:30,016,600...30,253,547 		JBrowse link
G DUSP1 dual specificity phosphatase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:39,588,833...39,591,065
Ensembl chr 4:39,588,339...39,590,514 		JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr38:16,196,354...16,233,640
Ensembl chr38:16,196,635...16,231,315 		JBrowse link
G EZR ezrin involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:48,160,206...48,210,036
Ensembl chr 1:48,160,206...48,210,036 		JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3822965|PMID:18681888) MGI PMID:18681888 MGI:3822965 NCBI chr25:8,972,942...8,998,404
Ensembl chr25:8,972,724...8,997,893 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:22696064) BHF-UCL PMID:22696064 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4366202|PMID:19696743) MGI
Ensembl		 PMID:19696743 GO_REF:0000107 MGI:4366202 NCBI chr38:16,196,354...16,233,640
Ensembl chr38:16,196,635...16,231,315 		JBrowse link
G FOXM1 forkhead box M1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr27:41,894,605...41,905,656
Ensembl chr27:41,894,672...41,905,663 		JBrowse link
G FOXO1 forkhead box O1 involved_in ISO (PMID:19696738) BHF-UCL PMID:19696738 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (MGI:5009411|PMID:16023107) BHF-UCL PMID:16023107 MGI:5009411 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in ISO (PMID:17438131) UniProt PMID:17438131 NCBI chr  X:54,558,515...54,612,029
Ensembl chr  X:54,547,446...54,613,171 		JBrowse link
G LOC403581 peptidylprolyl isomerase A (cyclophilin A) pseudogene involved_in ISO (PMID:26095851) UniProt PMID:26095851 NCBI chr 7:80,937,433...80,938,175 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IMP (PMID:19545562) UniProt
UniProt		 PMID:19545562 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within ISO (MGI:5293269|PMID:21715333) MGI PMID:21715333 MGI:5293269 NCBI chr25:29,751,805...29,781,806
Ensembl chr25:29,751,848...29,781,300 		JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,077,856...40,085,100
Ensembl chr20:40,078,163...40,085,099 		JBrowse link
positive regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129 		JBrowse link
G ANKRD6 ankyrin repeat domain 6 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:48,646,173...48,844,231
Ensembl chr12:48,646,173...48,842,451 		JBrowse link
G APP amyloid beta precursor protein involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3797993|PMID:18316368) MGI
Ensembl		 PMID:18316368 GO_REF:0000107 MGI:3797993 NCBI chr 6:40,155,797...40,218,330
Ensembl chr 6:40,158,244...40,218,343 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:46,950,700...46,956,375
Ensembl chr24:46,952,474...46,955,495 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17187069)
(MGI:3697751|PMID:17187069)		 Ensembl
Ensembl
MGI		 PMID:17187069 GO_REF:0000107 MGI:3697751 NCBI chr 9:49,110,913...49,120,758
Ensembl chr 9:49,113,923...49,120,591 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,375,107...51,375,790 JBrowse link
G CCN2 cellular communication network factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145 		JBrowse link
G CD27 CD27 molecule involved_in ISO (MGI:3687722|PMID:9692890) UniProt PMID:9692890 MGI:3687722 NCBI chr27:38,534,704...38,537,806
Ensembl chr27:38,534,707...38,537,604 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:2667426|PMID:12832451) MGI PMID:12832451 MGI:2667426 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G CRACR2A calcium release activated channel regulator 2A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:41,090,906...41,228,677
Ensembl chr27:41,094,009...41,217,919 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO RGD PMID:12198159 RGD:1298803 NCBI chr 9:45,594,657...45,627,499
Ensembl chr 9:45,598,899...45,627,589 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in ISO (MGI:5442512|PMID:15894542) GO_Central PMID:15894542 MGI:5442512 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:17389591), (PMID:19903888) UniProt PMID:17389591 PMID:19903888 NCBI chr 9:60,725,887...60,918,242
Ensembl chr 9:60,726,809...60,918,139 		JBrowse link
G DIXDC1 DIX domain containing 1 ISO RGD PMID:19339625 RGD:2308917 NCBI chr 5:21,097,000...21,168,470
Ensembl chr 5:21,100,045...21,167,166 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr36:26,095,436...26,111,700
Ensembl chr36:26,095,463...26,111,774 		JBrowse link
G DUSP22 dual specificity phosphatase 22 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:21873635)
(MGI:2387732|PMID:12138158)		 GO_Central
MGI		 PMID:12138158 PMID:21873635 MGI:2387732 NCBI chr35:678,320...733,225
Ensembl chr35:678,155...732,397 		JBrowse link
G EDAR ectodysplasin A receptor involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:34,873,311...34,943,140
Ensembl chr10:34,848,526...34,940,784 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in ISO (PMID:11413129) UniProt PMID:11413129 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (MGI:5514474|PMID:23921129) ARUK-UCL PMID:23921129 MGI:5514474 NCBI chr38:20,980,777...20,994,403 JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 ISO RGD PMID:9668039 RGD:1299389 NCBI chr27:16,252,405...16,464,099
Ensembl chr27:16,254,542...16,464,112 		JBrowse link
G FGF19 fibroblast growth factor 19 involved_in ISO (PMID:12815072) UniProt PMID:12815072 NCBI chr18:48,464,931...48,469,967
Ensembl chr18:48,464,928...48,469,782 		JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 involved_in ISO (PMID:16076871) UniProt PMID:16076871 NCBI chr11:1,145,643...1,184,097
Ensembl chr11:1,145,585...1,185,165 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:77,393,026...77,396,473
Ensembl chr 6:77,393,036...77,396,618 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta involved_in ISO (PMID:9827804) UniProt PMID:9827804 NCBI chr20:56,627,915...56,629,960
Ensembl chr20:56,628,485...56,629,730 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:96,745,001...96,746,535
Ensembl chr 1:96,744,985...96,746,520 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:15671867 RGD:1358666 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL1B interleukin 1 beta acts_upstream_of_or_within
involved_in		 ISO (MGI:3607973|PMID:16260493)
(MGI:5902681|PMID:20739563)		 RGD
MGI
ARUK-UCL		 PMID:15671867 PMID:16260493 PMID:20739563 MGI:3607973 MGI:5902681 RGD:1358666 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (MGI:3032484|PMID:14967141) MGI PMID:14967141 MGI:3032484 NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668 		JBrowse link
G LOC403934 cell division cycle 42 ISO RGD PMID:17161586 RGD:2298583 NCBI chr 2:77,153,276...77,169,947
Ensembl chr 2:77,153,095...77,199,211 		JBrowse link
G LTBR lymphotoxin beta receptor involved_in ISO (PMID:20732415) UniProt PMID:20732415 NCBI chr27:38,598,725...38,605,829
Ensembl chr27:38,599,268...38,605,780 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:17064355 RGD:2298577 NCBI chr 5:36,142,610...36,243,673
Ensembl chr 5:36,118,388...36,241,296 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO
IEA		 RGD
Ensembl		 PMID:10051439 PMID:11849756 PMID:17064355 GO_REF:0000107 RGD:2298561 RGD:2298565 RGD:2298577 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,918,210...43,996,817
Ensembl chr 2:43,917,604...43,995,209 		JBrowse link
G MAP3K10 mitogen-activated protein kinase kinase kinase 10 involved_in ISO (PMID:17584736) UniProt PMID:17584736 NCBI chr 1:113,422,239...113,435,979
Ensembl chr 1:113,422,518...113,428,688 		JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO (PMID:17584736) RGD
UniProt		 PMID:17064355 PMID:17584736 RGD:2298577 NCBI chr18:51,593,641...51,609,245
Ensembl chr18:51,594,274...51,608,696 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:29,107,813...29,306,437
Ensembl chr 1:29,108,591...29,306,503 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 involved_in ISO (PMID:17584736) UniProt PMID:17584736 NCBI chr18:52,353,606...52,367,065
Ensembl chr18:52,353,232...52,366,712 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (MGI:86683|PMID:9135144) UniProt PMID:9135144 MGI:86683 NCBI chr10:41,088,020...41,276,801
Ensembl chr10:41,089,371...41,276,891 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISO (MGI:5546548|PMID:23963642) UniProt PMID:23963642 MGI:5546548 NCBI chr18:43,517,186...43,522,603
Ensembl chr18:43,517,677...43,526,379 		JBrowse link
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 involved_in ISO PMID:21076496 UniProt PMID:21076496 RGD:13673827 NCBI chr 6:39,132,746...39,179,427
Ensembl chr 6:39,133,965...39,179,505 		JBrowse link
G MAPKBP1 mitogen-activated protein kinase binding protein 1 acts_upstream_of_or_within ISO (MGI:1344829|PMID:10471813) MGI PMID:10471813 MGI:1344829 NCBI chr30:8,807,584...8,857,693
Ensembl chr30:8,807,993...8,857,920 		JBrowse link
G MBIP MAP3K12 binding inhibitory protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:14,883,317...14,908,664
Ensembl chr 8:14,886,638...14,908,610 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28471450) UniProt PMID:28471450 NCBI chr16:35,579,531...35,676,552
Ensembl chr16:35,579,585...35,674,063 		JBrowse link
G MINK1 misshapen like kinase 1 involved_in ISO (PMID:15469942)
(MGI:1354211|PMID:10708748)		 UniProt PMID:10708748 PMID:15469942 MGI:1354211 NCBI chr 5:31,707,975...31,718,013
Ensembl chr 5:31,708,553...31,749,842 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:29,036,381...29,047,180
Ensembl chr 5:29,035,820...29,046,808 		JBrowse link
G MTURN maturin, neural progenitor differentiation regulator homolog involved_in ISO (PMID:24681962) UniProt PMID:24681962 NCBI chr14:42,890,343...42,928,985
Ensembl chr14:42,899,944...42,930,117 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2669022|PMID:12855817) MGI
Ensembl		 PMID:12855817 GO_REF:0000107 MGI:2669022 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3775161|PMID:18261938) Ensembl
Ensembl
MGI		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr14:43,162,671...43,226,948
Ensembl chr14:43,163,571...43,227,103 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938)
(PMID:17187069)		 MGI PMID:17187069 PMID:18261938 MGI:3775161 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G NOX1 NADPH oxidase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4881403|PMID:19661248) MGI
Ensembl
Ensembl		 PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698 		JBrowse link
G NRK Nik related kinase acts_upstream_of_or_within ISO (MGI:1860727|PMID:10801798) MGI PMID:10801798 MGI:1860727 NCBI chr  X:79,341,449...79,488,046
Ensembl chr  X:79,341,412...79,485,661 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,689,238...2,797,142
Ensembl chr 3:2,751,201...2,794,381 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in ISO (PMID:9500449) BHF-UCL PMID:9500449 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) UniProt PMID:19933860 NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810 		JBrowse link
G RASSF2 Ras association domain family member 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(PMID:19962960)		 GO_Central
Ensembl
Ensembl
MGI		 PMID:19962960 PMID:21873635 GO_REF:0000107 NCBI chr24:16,736,786...16,779,910
Ensembl chr24:16,736,962...16,781,569 		JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3689241|PMID:17015619) Ensembl
Ensembl
MGI		 PMID:17015619 GO_REF:0000107 MGI:3689241 NCBI chr29:4,445,668...4,544,223
Ensembl chr29:4,375,785...4,517,168 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17389591)
(MGI:5306563|PMID:20125124)		 UniProt PMID:17389591 PMID:20125124 MGI:5306563 NCBI chr35:3,367,796...3,407,631
Ensembl chr35:3,263,226...3,405,883 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938)
(MGI:2176424|PMID:11894097)		 MGI
Ensembl		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036 		JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:20,025,920...20,208,470
Ensembl chr25:20,015,915...20,205,946 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:40,380,313...40,514,211
Ensembl chr 2:40,380,218...40,510,853 		JBrowse link
G SH3RF3 SH3 domain containing ring finger 3 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr10:34,374,376...34,730,548
Ensembl chr10:34,376,326...34,730,657 		JBrowse link
G SLAMF1 signaling lymphocytic activation molecule family member 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr38:21,653,801...21,685,408
Ensembl chr38:21,653,487...21,685,408 		JBrowse link
G STK3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4420852|PMID:20080598) Ensembl
MGI
Ensembl		 PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr13:647,363...920,887
Ensembl chr13:648,216...920,847 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 9:43,501,752...43,660,077
Ensembl chr 9:43,559,708...43,651,377 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:18,014,685...18,029,188
Ensembl chr 6:18,000,138...18,029,185 		JBrowse link
G TAOK3 TAO kinase 3 involved_in ISO (PMID:10924369) HGNC-UCL PMID:10924369 NCBI chr26:14,534,083...14,712,779
Ensembl chr26:14,534,901...14,631,899 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISO (PMID:11544529) BHF-UCL PMID:11544529 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G TLR3 toll like receptor 3 acts_upstream_of_or_within ISO (MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3607973|PMID:16260493)
(MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938)		 MGI
Ensembl		 PMID:16260493 PMID:18261938 GO_REF:0000107 MGI:3607973 MGI:3775161 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TMEM219 transmembrane protein 219 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,959,490...18,014,813
Ensembl chr 6:18,000,138...18,029,185 		JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3607973|PMID:16260493), (MGI:4420852|PMID:20080598) Ensembl
Ensembl
MGI		 PMID:16260493 PMID:20080598 GO_REF:0000107 MGI:3607973 MGI:4420852 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TNFRSF19 TNF receptor superfamily member 19 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:14,985,893...15,075,701
Ensembl chr25:14,927,599...15,055,449 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5308511|PMID:22073305) Ensembl
Ensembl
MGI		 PMID:22073305 GO_REF:0000107 MGI:5308511 NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:35,426,716...35,727,308
Ensembl chr34:35,427,217...35,807,059 		JBrowse link
G TPD52L1 TPD52 like 1 involved_in ISO (PMID:14761963) UniProt PMID:14761963 NCBI chr 1:64,165,833...64,216,851
Ensembl chr 1:64,125,934...64,216,787 		JBrowse link
G TRAF1 TNF receptor associated factor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:73,920,729...73,939,644
Ensembl chr11:73,927,007...73,937,655 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:70,739,389...70,794,448
Ensembl chr 8:70,739,417...70,790,645 		JBrowse link
G TRAF4 TNF receptor associated factor 4 involved_in IBA
IEA		 (PMID:21873635) GO_Central
InterPro		 PMID:21873635 GO_REF:0000002 NCBI chr 9:42,933,638...42,940,033
Ensembl chr 9:42,933,750...42,939,520 		JBrowse link
G TRAF5 TNF receptor associated factor 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:9,812,019...9,831,955
Ensembl chr 7:9,812,132...9,831,955 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (MGI:5440106|PMID:23021218) UniProt PMID:23021218 MGI:5440106 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165 		JBrowse link
G UNC5CL unc-5 family C-terminal like involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:21873635)
(PMID:22158417)		 GO_Central
MGI		 PMID:21873635 PMID:22158417 NCBI chr12:9,782,411...9,794,822
Ensembl chr12:9,783,963...9,794,690 		JBrowse link
G WNT16 Wnt family member 16 involved_in ISO (PMID:17200136) BHF-UCL PMID:17200136 NCBI chr14:59,388,034...59,404,812
Ensembl chr14:59,387,846...59,396,622 		JBrowse link
G WNT5A Wnt family member 5A acts_upstream_of
involved_in		 ISO
IEA		 (MGI:4820702|PMID:20032469) BHF-UCL
Ensembl
Ensembl		 PMID:20032469 GO_REF:0000107 MGI:4820702 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
G WNT7A Wnt family member 7A involved_in IBA
ISO		 (PMID:21873635) GO_Central
RGD		 PMID:18567805 PMID:21873635 RGD:4107045 NCBI chr20:4,072,010...4,139,521
Ensembl chr20:4,073,929...4,139,436 		JBrowse link
G WNT7B Wnt family member 7B involved_in ISO
IBA		 (PMID:21873635) RGD
GO_Central		 PMID:18177422 PMID:21873635 RGD:2292645 NCBI chr10:20,160,916...20,208,786
Ensembl chr10:20,160,206...20,243,160 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
G ZNF622 zinc finger protein 622 involved_in ISO (PMID:21771788) UniProt PMID:21771788 NCBI chr 4:86,929,947...86,943,711
Ensembl chr 4:86,826,892...86,951,542 		JBrowse link
positive regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 7:41,835,322...41,850,488
Ensembl chr 7:41,812,353...41,850,488 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in ISO (PMID:22540193) DFLAT PMID:22540193 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:18584881 RGD:2303073 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:77,393,026...77,396,473
Ensembl chr 6:77,393,036...77,396,618 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta involved_in ISO (PMID:9827804) UniProt PMID:9827804 NCBI chr20:56,627,915...56,629,960
Ensembl chr20:56,628,485...56,629,730 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:96,745,001...96,746,535
Ensembl chr 1:96,744,985...96,746,520 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in ISO (MGI:5751611|PMID:26774823) UniProt PMID:26774823 MGI:5751611 NCBI chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174 		JBrowse link
G HAND2 heart and neural crest derivatives expressed 2 involved_in ISO (PMID:24161931) BHF-UCL PMID:24161931 NCBI chr25:24,140,496...24,143,143
Ensembl chr25:24,141,243...24,152,958 		JBrowse link
G IL1B interleukin 1 beta involved_in ISO (MGI:5902681|PMID:20739563) ARUK-UCL PMID:20739563 MGI:5902681 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G LEP leptin involved_in ISS
IBA
IEA		 (PMID:21873635) UniProt
GO_Central
GO_Central
UniProt
Ensembl		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1353859|PMID:10700190) Ensembl
MGI		 PMID:10700190 GO_REF:0000107 MGI:1353859 NCBI chr 9:11,612,527...11,678,407
Ensembl chr 9:11,612,994...11,675,838 		JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:9305639) UniProt PMID:9305639 NCBI chr 1:49,590,615...49,702,289
Ensembl chr 1:49,548,274...49,702,289 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:20716917 RGD:10412640 NCBI chr 1:29,107,813...29,306,437
Ensembl chr 1:29,108,591...29,306,503 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:5529574|PMID:23994610) MGI PMID:23994610 MGI:5529574 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28471450) UniProt PMID:28471450 NCBI chr16:35,579,531...35,676,552
Ensembl chr16:35,579,585...35,674,063 		JBrowse link
G MINK1 misshapen like kinase 1 involved_in ISO (MGI:1354211|PMID:10708748) UniProt PMID:10708748 MGI:1354211 NCBI chr 5:31,707,975...31,718,013
Ensembl chr 5:31,708,553...31,749,842 		JBrowse link
G MIR181A-1 microRNA mir-181a-1 involved_in ISO (PMID:23993976) BHF-UCL PMID:23993976 NCBI chr 7:4,055,465...4,055,526
Ensembl chr 7:4,055,465...4,055,526 		JBrowse link
G MIR181A-2 microRNA mir-181a-2 involved_in ISO (PMID:23993976) BHF-UCL PMID:23993976 NCBI chr 9:58,302,547...58,302,606
Ensembl chr 9:58,302,547...58,302,606 		JBrowse link
G MIR181B-2 microRNA mir-181b-2 involved_in ISO (PMID:23993976) BHF-UCL PMID:23993976 NCBI chr 9:58,301,314...58,301,373
Ensembl chr 9:58,301,300...58,301,388 		JBrowse link
G MIR181D microRNA mir-181d involved_in ISO (PMID:23993976) BHF-UCL PMID:23993976 NCBI chr20:48,593,158...48,593,221 JBrowse link
G NCF1 neutrophil cytosolic factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458 		JBrowse link
G OPRK1 opioid receptor kappa 1 ISO RGD PMID:16648139 RGD:9831415 NCBI chr29:5,022,270...5,054,223
Ensembl chr29:5,025,786...5,051,919 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,689,238...2,797,142
Ensembl chr 3:2,751,201...2,794,381 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISO PMID:23483889 BHF-UCL PMID:23483889 RGD:10047341 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G RELL1 RELT like 1 involved_in IBA
IEA		 (PMID:21873635) GO_Central
InterPro
InterPro		 PMID:21873635 GO_REF:0000002 NCBI chr 3:74,493,133...74,555,976
Ensembl chr 3:74,489,571...74,554,086 		JBrowse link
G RELL1 RELT like 1 involved_in IEA InterPro GO_REF:0000002
G RELL2 RELT like 2 involved_in IBA
IEA		 (PMID:21873635) GO_Central
InterPro		 PMID:21873635 GO_REF:0000002 NCBI chr 2:36,598,175...36,602,607
Ensembl chr 2:36,599,149...36,602,020 		JBrowse link
G SASH1 SAM and SH3 domain containing 1 acts_upstream_of_or_within ISO (PMID:23776175) MGI PMID:23776175 NCBI chr 1:39,221,243...39,478,057
Ensembl chr 1:39,146,020...39,476,914 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,311,698...4,314,773
Ensembl chr 9:4,311,683...4,314,483 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISO (MGI:6478061|PMID:28912174) ARUK-UCL PMID:28912174 MGI:6478061 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in ISO PMID:10980603
(PMID:10980603)		 UniProt PMID:10980603 RGD:727300 NCBI chr36:12,866,867...13,118,736
Ensembl chr36:12,867,188...13,183,160 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (PMID:18386220) UniProt PMID:18386220 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
G XDH xanthine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371 		JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:22,632,613...22,653,894
Ensembl chr20:22,633,808...22,653,870 		JBrowse link
G CARD9 caspase recruitment domain family member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3697751|PMID:17187069)
(PMID:17187069)		 MGI
Ensembl		 PMID:17187069 GO_REF:0000107 MGI:3697751 NCBI chr 9:49,110,913...49,120,758
Ensembl chr 9:49,113,923...49,120,591 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19211730 RGD:5130956 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr17:29,494,641...29,537,933
Ensembl chr17:29,496,128...29,537,933 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:17161379 RGD:5508698 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 involved_in ISO (PMID:24003225) UniProt PMID:24003225 NCBI chr27:2,063,548...2,067,366
Ensembl chr27:1,989,772...2,067,298 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:15671867 RGD:1358666 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:12629164 PMID:15671867 RGD:1358666 RGD:1626685 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL26 interleukin 26 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr10:10,457,091...10,471,547
Ensembl chr10:10,457,083...10,471,582 		JBrowse link
G INAVA innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chr 7:2,264,120...2,284,196 JBrowse link
G KISS1 KiSS-1 metastasis suppressor NOT ISO RGD PMID:16222076 RGD:1599289 NCBI chr38:768,333...774,328
Ensembl chr38:768,585...773,382 		JBrowse link
G KLHDC10 kelch domain containing 10 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:6,750,269...6,771,690
Ensembl chr14:6,755,070...6,781,604 		JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 ISO RGD PMID:12024021 RGD:2302280 NCBI chr10:16,702,623...16,712,426
Ensembl chr10:16,702,621...16,712,278 		JBrowse link
G MID1 midline 1 involved_in ISO (PMID:17438131) UniProt PMID:17438131 NCBI chr  X:7,087,890...7,438,553
Ensembl chr  X:7,089,831...7,194,267 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr14:43,162,671...43,226,948
Ensembl chr14:43,163,571...43,227,103 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938)
(PMID:17187069)		 MGI PMID:17187069 PMID:18261938 MGI:3775161 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G PDCD10 programmed cell death 10 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr34:32,512,109...32,553,524
Ensembl chr34:32,512,112...32,553,445 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938)
(MGI:2176424|PMID:11894097)		 MGI
Ensembl		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) UniProt PMID:27288407 MGI:5803730 NCBI chr 5:31,534,470...31,551,441
Ensembl chr 5:31,534,226...31,549,175 		JBrowse link
G SEMA4C semaphorin 4C involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr10:45,105,701...45,116,504
Ensembl chr10:45,106,666...45,115,592 		JBrowse link
G STK25 serine/threonine kinase 25 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr25:51,425,597...51,434,479
Ensembl chr25:51,425,597...51,434,479 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:43,501,752...43,660,077
Ensembl chr 9:43,559,708...43,651,377 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,014,685...18,029,188
Ensembl chr 6:18,000,138...18,029,185 		JBrowse link
G TAOK3 TAO kinase 3 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chr26:14,534,083...14,712,779
Ensembl chr26:14,534,901...14,631,899 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISS
IEA		 AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) MGI PMID:18261938 MGI:3775161 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
positive regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G RNF13 ring finger protein 13 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr23:44,480,595...44,683,114
Ensembl chr23:44,529,389...44,682,111 		JBrowse link
regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr29:16,562,234...16,579,082
Ensembl chr29:16,562,234...16,578,847 		JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO (PMID:26514923) CAFA PMID:26514923 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G EPHB1 EPH receptor B1 involved_in ISO (PMID:9430661) UniProt PMID:9430661 NCBI chr23:31,485,701...31,918,754
Ensembl chr23:31,485,534...31,917,393 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in ISO (PMID:16410250) UniProt PMID:16410250 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 involved_in ISO PMID:11152698 UniProt PMID:11152698 RGD:8554109 NCBI chr12:58,932,754...59,991,305
Ensembl chr12:59,355,017...59,990,408 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387 		JBrowse link
G MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr17:62,055,705...62,290,808
Ensembl chr17:62,057,610...62,291,157 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (PMID:14966141) UniProt PMID:14966141 NCBI chr10:41,088,020...41,276,801
Ensembl chr10:41,089,371...41,276,891 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:43,517,186...43,522,603
Ensembl chr18:43,517,677...43,526,379 		JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:16,702,623...16,712,426
Ensembl chr10:16,702,621...16,712,278 		JBrowse link
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 involved_in ISO (MGI:1352260|PMID:10629060) UniProt PMID:10629060 MGI:1352260 NCBI chr 6:39,132,746...39,179,427
Ensembl chr 6:39,133,965...39,179,505 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:17348686 RGD:2298766 NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119 		JBrowse link
G MDFI MyoD family inhibitor involved_in ISO (MGI:4441137|PMID:12192039) UniProt PMID:12192039 MGI:4441137 NCBI chr12:10,324,499...10,339,699
Ensembl chr12:10,323,552...10,339,697 		JBrowse link
G MDFIC MyoD family inhibitor domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:54,063,832...54,153,346
Ensembl chr14:54,063,769...54,166,197 		JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 involved_in ISO (PMID:17386267) UniProt PMID:17386267 NCBI chr 1:14,027,741...14,234,229
Ensembl chr 1:14,028,652...14,234,229 		JBrowse link
G RAP2A RAP2A, member of RAS oncogene family involved_in ISO (PMID:14966141) UniProt PMID:14966141 NCBI chr22:47,777,621...47,814,061
Ensembl chr22:47,778,780...47,810,802 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:10811109 RGD:11534984 NCBI chr 9:52,429,204...52,566,775
Ensembl chr 9:52,450,597...52,563,778 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr 2:40,380,313...40,514,211
Ensembl chr 2:40,380,218...40,510,853 		JBrowse link
G SH3RF3 SH3 domain containing ring finger 3 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr10:34,374,376...34,730,548
Ensembl chr10:34,376,326...34,730,657 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 NOT|involved_in ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TRAF2 TNF receptor associated factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2680840|PMID:12958312) MGI
InterPro
Ensembl
Ensembl		 PMID:12958312 GO_REF:0000002 GO_REF:0000107 MGI:2680840 NCBI chr 9:48,688,071...48,713,936
Ensembl chr 9:48,689,331...48,703,633 		JBrowse link
G ULK4 unc-51 like kinase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24284070) MGI
Ensembl
Ensembl		 PMID:24284070 GO_REF:0000107 NCBI chr23:10,578,391...11,176,543
Ensembl chr23:10,578,429...11,176,545 		JBrowse link
G ZNF274 zinc finger protein 274 involved_in ISO (MGI:3579762|PMID:15668238) UniProt PMID:15668238 MGI:3579762 NCBI chr 1:99,696,295...99,719,559
Ensembl chr 1:99,697,185...99,719,455 		JBrowse link
regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129 		JBrowse link
G CAV3 caveolin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4946902|PMID:21182936) Ensembl
Ensembl
MGI		 PMID:21182936 GO_REF:0000107 MGI:4946902 NCBI chr20:9,384,901...9,398,055
Ensembl chr20:9,384,901...9,401,196 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (MGI:4453088|PMID:19948740) UniProt PMID:19948740 MGI:4453088 NCBI chr 9:60,725,887...60,918,242
Ensembl chr 9:60,726,809...60,918,139 		JBrowse link
G HGF hepatocyte growth factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5529574|PMID:23994610) Ensembl
MGI
Ensembl		 PMID:23994610 GO_REF:0000107 MGI:5529574 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G PER1 period circadian regulator 1 involved_in ISO PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr 5:32,957,517...32,972,368
Ensembl chr 5:32,957,127...32,968,465 		JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 involved_in ISO (PMID:17386267) UniProt PMID:17386267 NCBI chr 1:14,027,741...14,234,229
Ensembl chr 1:14,028,652...14,234,229 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 NOT|involved_in ISO (PMID:19933860) UniProt PMID:19933860 NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 NOT|involved_in ISO (MGI:5440106|PMID:23021218) UniProt PMID:23021218 MGI:5440106 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165 		JBrowse link
G ULK4 unc-51 like kinase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24284070) MGI
Ensembl
Ensembl		 PMID:24284070 GO_REF:0000107 NCBI chr23:10,578,391...11,176,543
Ensembl chr23:10,578,429...11,176,545 		JBrowse link
regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAS Fas cell surface death receptor involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISO (MGI:5318033|PMID:12135612) BHF-UCL PMID:12135612 MGI:5318033 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (MGI:5009198|PMID:10945608) BHF-UCL PMID:10945608 MGI:5009198 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA UniProt
UniProt		 GO_REF:0000117 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G NBR1 NBR1 autophagy cargo receptor involved_in ISO (MGI:4818844|PMID:20616007) BHF-UCL PMID:20616007 MGI:4818844 NCBI chr 9:19,926,885...19,959,552
Ensembl chr 9:19,915,973...19,958,789 		JBrowse link
G PRDX1 peroxiredoxin 1 acts_upstream_of_or_within ISO (MGI:3695235|PMID:16880205) MGI PMID:16880205 MGI:3695235 NCBI chr15:14,834,009...14,855,665
Ensembl chr15:14,838,652...14,862,971 		JBrowse link
G TMEM106A transmembrane protein 106A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,917,591...19,926,578
Ensembl chr 9:19,915,973...19,958,789 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17242
    cellular process 16248
      regulation of cellular process 11070
        regulation of cellular response to stress 718
          regulation of stress-activated protein kinase signaling cascade 212
            negative regulation of stress-activated protein kinase signaling cascade + 50
            positive regulation of stress-activated protein kinase signaling cascade + 142
            regulation of stress-activated MAPK cascade + 209
Path 2
Term Annotations click to browse term
  biological_process 17242
    biological regulation 12426
      regulation of biological process 11765
        regulation of cellular process 11070
          signal transduction 6042
            intracellular signal transduction 2684
              regulation of intracellular signal transduction 1738
                regulation of stress-activated protein kinase signaling cascade 212
                  negative regulation of stress-activated protein kinase signaling cascade + 50
                  positive regulation of stress-activated protein kinase signaling cascade + 142
                  regulation of stress-activated MAPK cascade + 209
paths to the root