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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of stress-activated protein kinase signaling cascade
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Accession:GO:0070302 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.
Synonyms:exact_synonym: regulation of SAPK signaling pathway;   regulation of stress-activated protein kinase signaling pathway;   regulation of stress-activated protein kinase signalling pathway


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regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3789238|PMID:16079796) MGI
Ensembl		 PMID:16079796 GO_REF:0000107 MGI:3789238 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747 		JBrowse link
negative regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated involved_in ISO (MGI:3799599|PMID:17681137) UniProt PMID:17681137 MGI:3799599 NCBI chr 1:198,341,375...198,385,682 JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:17064355 RGD:2298577 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:3693042|PMID:17081782) MGI PMID:17081782 MGI:3693042 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:31,004,393...31,064,546
Ensembl chr16:49,882,751...49,942,629 		JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:39,231,910...39,242,353
Ensembl chr14:57,499,906...57,510,019 		JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3051749|PMID:15306813) MGI
Ensembl		 PMID:15306813 GO_REF:0000107 MGI:3051749 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,618,860...13,631,743
Ensembl chr17:13,784,594...13,797,045 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265 		JBrowse link
G FKTN fukutin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:76,723,071...76,821,611
Ensembl chr 9:104,849,496...104,925,422
Ensembl chr 9:104,849,496...104,925,422 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,346,766...7,349,682
Ensembl chr17:7,333,571...7,335,871 		JBrowse link
G HDAC3 histone deacetylase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:136,981,790...136,997,786
Ensembl chr 5:143,094,406...143,110,322 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:30,690,172...30,840,504
Ensembl chr20:31,852,203...31,971,945 		JBrowse link
G KLHL31 kelch like family member 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,201,483...53,351,320
Ensembl chr 6:54,839,066...54,893,640 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 ISO RGD PMID:12064607 RGD:1299562 NCBI chr11:45,839,754...45,860,615
Ensembl chr11:46,332,159...46,352,010 		JBrowse link
G MARVELD3 MARVEL domain containing 3 acts_upstream_of_or_within ISO (PMID:24567356) MGI PMID:24567356 NCBI chr16:53,369,080...53,385,031
Ensembl chr16:71,463,824...71,477,631 		JBrowse link
G MECOM MDS1 and EVI1 complex locus involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:166,099,530...166,677,739
Ensembl chr 3:174,154,814...174,731,252 		JBrowse link
G MEN1 menin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,934,452...35,121,195 JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5308511|PMID:22073305) MGI
Ensembl		 PMID:22073305 GO_REF:0000107 MGI:5308511 NCBI chr17:2,584,349...2,676,928
Ensembl chr17:2,590,007...2,680,994 		JBrowse link
G PER1 period circadian regulator 1 involved_in ISO PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr17:43,502,080...43,518,098
Ensembl chr17:48,234,360...48,250,391 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,691,795...46,705,179
Ensembl chr19:55,610,938...55,623,135 		JBrowse link
G SFRP4 secreted frizzled related protein 4 ISO RGD PMID:18567805 RGD:4107045 NCBI chr 7:38,542,105...38,553,008
Ensembl chr 7:38,764,146...38,774,264 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in ISO PMID:22128169 UniProt PMID:22128169 RGD:13673844 NCBI chr 5:141,386,060...141,530,993
Ensembl chr 5:147,401,188...147,545,703 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106 		JBrowse link
G TAOK3 TAO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:115,730,619...115,954,149
Ensembl chr12:119,109,642...119,226,502 		JBrowse link
G ZMYND11 zinc finger MYND-type containing 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:139,879...264,711
Ensembl chr10:226,880...346,369 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated acts_upstream_of_or_within ISO (MGI:3799599|PMID:17681137)
(PMID:17681137)		 MGI PMID:17681137 MGI:3799599 NCBI chr 1:198,341,375...198,385,682 JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:32,800,077...32,814,745
Ensembl chr 9:33,608,502...33,622,275 		JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3051749|PMID:15306813) MGI
Ensembl		 PMID:15306813 GO_REF:0000107 MGI:3051749 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G DUSP16 dual specificity phosphatase 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,497,185...12,585,591
Ensembl chr12:12,865,400...12,912,502 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G HIPK3 homeodomain interacting protein kinase 3 involved_in ISO (MGI:1913166|PMID:11034606) UniProt PMID:11034606 MGI:1913166 NCBI chr11:33,230,731...33,330,617
Ensembl chr11:33,114,534...33,212,783 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISO PMID:21076496 RGD
UniProt		 PMID:12064607 PMID:21076496 RGD:1299562 RGD:13673827 NCBI chr11:45,839,754...45,860,615
Ensembl chr11:46,332,159...46,352,010 		JBrowse link
G NPPA natriuretic peptide A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830 		JBrowse link
G SFRP1 secreted frizzled related protein 1 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3839161|PMID:19300477) Ensembl
MGI		 PMID:19300477 GO_REF:0000107 MGI:3839161 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258 		JBrowse link
G SFRP5 secreted frizzled related protein 5 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr10:94,383,269...94,389,053
Ensembl chr10:97,877,790...97,882,850 		JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (MGI:3574697|PMID:15483136) MGI PMID:15483136 MGI:3574697 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206 		JBrowse link
negative regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYLD CYLD lysine 63 deubiquitinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:31,004,393...31,064,546
Ensembl chr16:49,882,751...49,942,629 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987 		JBrowse link
G DUSP1 dual specificity phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960 		JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G EZR ezrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:156,656,146...156,709,986
Ensembl chr 6:161,670,483...161,723,102 		JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3822965|PMID:18681888) MGI PMID:18681888 MGI:3822965 NCBI chr13:12,412,826...12,438,563
Ensembl chr13:30,846,631...30,871,161 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4366202|PMID:19696743) MGI
Ensembl		 PMID:19696743 GO_REF:0000107 MGI:4366202 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G FOXM1 forkhead box M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,978,400...2,999,077
Ensembl chr12:2,910,028...2,930,503 		JBrowse link
G FOXO1 forkhead box O1 involved_in ISO (PMID:19696738) BHF-UCL PMID:19696738 NCBI chr13:21,763,729...21,874,279 JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (MGI:5009411|PMID:16023107) BHF-UCL PMID:16023107 MGI:5009411 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:59,401,426...59,434,363
Ensembl chr  X:69,460,734...69,493,616 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5293269|PMID:21715333) MGI
Ensembl		 PMID:21715333 GO_REF:0000107 MGI:5293269 NCBI chr 8:27,084,789...27,112,986
Ensembl chr 8:24,285,395...24,313,658 		JBrowse link
G PPIA peptidylprolyl isomerase A involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545 		JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in ISO (PMID:11096076) CAFA PMID:11096076 NCBI chr 3:49,020,310...49,029,443
Ensembl chr 3:50,100,216...50,125,112 		JBrowse link
positive regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G APP amyloid beta precursor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3797993|PMID:18316368) MGI
Ensembl		 PMID:18316368 GO_REF:0000107 MGI:3797993 Ensembl chr16:278,239...337,891 JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:59,618,530...59,623,612
Ensembl chr20:61,157,302...61,161,932 		JBrowse link
G CARD9 caspase recruitment domain family member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3697751|PMID:17187069)
(PMID:17187069)		 MGI
Ensembl		 PMID:17187069 GO_REF:0000107 MGI:3697751 NCBI chr 9:107,432,709...107,446,271
Ensembl chr 9:136,416,279...136,424,756 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,545,248...34,546,801
Ensembl chr 9:35,353,768...35,354,924 		JBrowse link
G CCN2 cellular communication network factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G CD27 CD27 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,575,104...6,582,127
Ensembl chr12:6,492,119...6,499,427 		JBrowse link
G CDC42 cell division cycle 42 ISO RGD PMID:17161586 RGD:2298583 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:2667426|PMID:12832451) MGI PMID:12832451 MGI:2667426 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739 		JBrowse link
G CRACR2A calcium release activated channel regulator 2A involved_in ISO (PMID:27016526)
(MGI:6141997|PMID:27016526)		 UniProt PMID:27016526 MGI:6141997 NCBI chr12:3,729,241...3,875,715
Ensembl chr12:3,655,031...3,737,592 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO RGD PMID:12198159 RGD:1298803 NCBI chr17:1,406,335...1,438,587
Ensembl chr17:1,306,509...1,336,569 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in ISO (MGI:5442512|PMID:15894542) GO_Central PMID:15894542 MGI:5442512 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G DIXDC1 DIX domain containing 1 ISO RGD PMID:19339625 RGD:2308917 NCBI chr11:106,813,905...106,908,898
Ensembl chr11:110,657,803...110,753,114 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266 		JBrowse link
G DUSP22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:2387732|PMID:12138158) MGI PMID:12138158 MGI:2387732 NCBI chr 6:107,145...180,777
Ensembl chr 6:242,121...301,248 		JBrowse link
G EDA2R ectodysplasin A2 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:55,786,361...55,830,798
Ensembl chr  X:65,850,306...65,894,975 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265 		JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (MGI:5514474|PMID:23921129) ARUK-UCL PMID:23921129 MGI:5514474 NCBI chr 1:137,074,342...137,090,962
Ensembl chr 1:140,882,043...140,890,637 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 ISO RGD PMID:9668039 RGD:1299389 NCBI chr12:53,574,573...53,822,971
Ensembl chr12:56,181,565...56,421,810 		JBrowse link
G FGF19 fibroblast growth factor 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:64,794,157...64,800,512
Ensembl chr11:68,085,306...68,090,028 		JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:175,804,728...175,852,703
Ensembl chr 5:183,115,856...183,149,006 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,489,263...1,491,391
Ensembl chr19:2,451,837...2,453,992 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:60,695,307...60,696,860
Ensembl chr 9:88,740,411...88,741,958 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14678985) UniProt PMID:14678985 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:12765338) UniProt PMID:12765338 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527 		JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:15671867 RGD:1358666 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801 		JBrowse link
G IL1B interleukin 1 beta involved_in
acts_upstream_of_or_within		 ISO (MGI:5902681|PMID:20739563)
(MGI:3607973|PMID:16260493)		 RGD
ARUK-UCL
MGI		 PMID:15671867 PMID:16260493 PMID:20739563 MGI:3607973 MGI:5902681 RGD:1358666 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (MGI:3032484|PMID:14967141) MGI PMID:14967141 MGI:3032484 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213 		JBrowse link
G LTBR lymphotoxin beta receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,514,432...6,521,966
Ensembl chr12:6,422,470...6,438,510 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:17064355 RGD:2298577 NCBI chr17:39,497,105...39,622,331
Ensembl chr17:44,248,857...44,359,909 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO
IEA		 RGD
Ensembl		 PMID:10051439 PMID:11849756 PMID:17064355 GO_REF:0000107 RGD:2298561 RGD:2298565 RGD:2298577 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959 		JBrowse link
G MAP3K10 mitogen-activated protein kinase kinase kinase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:37,236,438...37,260,314
Ensembl chr19:45,753,354...45,775,137 		JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17064355 GO_REF:0000107 RGD:2298577 NCBI chr11:60,956,880...60,973,972
Ensembl chr11:64,291,635...64,307,737 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:134,316,841...134,582,843
Ensembl chr 6:138,406,398...138,641,727 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (MGI:3607973|PMID:16260493) MGI PMID:16260493 MGI:3607973 NCBI chr 6:88,398,329...88,470,926
Ensembl chr 6:91,664,263...91,737,468 		JBrowse link
G MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:60,142,445...60,158,728
Ensembl chr11:63,486,827...63,499,746 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (MGI:86683|PMID:9135144) UniProt PMID:9135144 MGI:86683 Ensembl chr2A:102,750,221...102,945,263 JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:45,839,754...45,860,615
Ensembl chr11:46,332,159...46,352,010 		JBrowse link
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 involved_in ISO PMID:21076496 UniProt PMID:21076496 RGD:13673827 NCBI chr16:327,995...392,691
Ensembl chr16:1,759,171...1,821,246 		JBrowse link
G MAPKBP1 mitogen-activated protein kinase binding protein 1 acts_upstream_of_or_within ISO (MGI:1344829|PMID:10471813) MGI PMID:10471813 MGI:1344829 NCBI chr15:20,713,859...20,768,224 JBrowse link
G MBIP MAP3K12 binding inhibitory protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:17,052,270...17,074,609
Ensembl chr14:35,231,398...35,253,746 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,318,455...10,428,469 JBrowse link
G MINK1 misshapen like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,879,851...4,944,374
Ensembl chr17:4,868,620...4,932,789 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:97,650,408...97,663,731
Ensembl chr11:101,143,268...101,156,736 		JBrowse link
G MTURN maturin, neural progenitor differentiation regulator homolog involved_in ISO (PMID:24681962) UniProt PMID:24681962 NCBI chr 7:30,766,592...30,794,436 JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2669022|PMID:12855817) MGI
Ensembl		 PMID:12855817 GO_REF:0000107 MGI:2669022 NCBI chr 3:38,036,565...38,041,014
Ensembl chr 3:38,319,024...38,323,572 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,345,623...44,401,358
Ensembl chr 5:45,920,125...45,973,937 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:81,917,167...81,932,589 JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
(PMID:17187069)		 MGI
Ensembl		 PMID:17187069 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G NOX1 NADPH oxidase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4881403|PMID:19661248) MGI
Ensembl		 PMID:19661248 GO_REF:0000107 MGI:4881403 NCBI chr  X:90,046,023...90,076,968
Ensembl chr  X:100,182,398...100,215,192 		JBrowse link
G NRK Nik related kinase acts_upstream_of_or_within ISO (MGI:1860727|PMID:10801798) MGI PMID:10801798 MGI:1860727 NCBI chr  X:94,957,923...95,094,749
Ensembl chr  X:105,337,327...105,470,331 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:104,688,464...104,759,669
Ensembl chr 5:110,497,245...110,541,354 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G RASSF2 Ras association domain family member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19962960) MGI
Ensembl		 PMID:19962960 GO_REF:0000107 NCBI chr20:4,804,802...4,845,633
Ensembl chr20:4,603,414...4,641,529 		JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3689241|PMID:17015619) MGI
Ensembl		 PMID:17015619 GO_REF:0000107 MGI:3689241 NCBI chr 8:49,046,830...49,138,795
Ensembl chr 8:46,430,131...46,521,722 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938)
(MGI:2176424|PMID:11894097)		 MGI
Ensembl		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,725,469...1,738,887
Ensembl chr17:1,618,549...1,631,570 		JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in ISO (MGI:5546548|PMID:23963642), (MGI:6158776|PMID:27084103) UniProt PMID:23963642 PMID:27084103 MGI:5546548 MGI:6158776 NCBI chr 4:161,319,093...161,495,917
Ensembl chr 4:173,394,739...173,567,096 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:141,386,060...141,530,993
Ensembl chr 5:147,401,188...147,545,703 		JBrowse link
G SH3RF3 SH3 domain containing ring finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:92,137,951...92,519,627
Ensembl chr2A:110,848,452...111,219,915 		JBrowse link
G SLAMF1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:20231852) UniProt PMID:20231852 NCBI chr 1:135,963,748...136,002,982
Ensembl chr 1:139,888,772...139,925,461 		JBrowse link
G STK3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4420852|PMID:20080598) Ensembl
MGI		 PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 8:95,098,185...95,465,324
Ensembl chr 8:97,355,173...97,708,437 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,222,725...27,385,713
Ensembl chr17:27,746,797...27,840,623 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,347,229...30,366,743 JBrowse link
G TAOK3 TAO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:115,730,619...115,954,149
Ensembl chr12:119,109,642...119,226,502 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:121,100,558...121,112,844
Ensembl chr11:125,018,064...125,022,309 		JBrowse link
G TLR3 toll like receptor 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3607973|PMID:16260493) MGI
Ensembl		 PMID:16260493 GO_REF:0000107 MGI:3607973 NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938) MGI
Ensembl		 PMID:16260493 PMID:18261938 GO_REF:0000107 MGI:3607973 MGI:3775161 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3607973|PMID:16260493), (MGI:4420852|PMID:20080598) MGI
Ensembl		 PMID:16260493 PMID:20080598 GO_REF:0000107 MGI:3607973 MGI:4420852 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TNFSF11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5308511|PMID:22073305) MGI
Ensembl		 PMID:22073305 GO_REF:0000107 MGI:5308511 NCBI chr13:23,750,835...23,784,740 JBrowse link
G TNIK TRAF2 and NCK interacting kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:168,067,839...168,466,290
Ensembl chr 3:176,255,547...176,650,795 		JBrowse link
G TPD52L1 TPD52 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:122,943,780...123,053,201
Ensembl chr 6:127,062,573...127,172,174 		JBrowse link
G TRAF4 TNF receptor associated factor 4 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr17:28,025,288...28,031,379
Ensembl chr17:28,531,867...28,536,994 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
G UNC5CL unc-5 family C-terminal like acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22158417) MGI
Ensembl		 PMID:22158417 GO_REF:0000107 NCBI chr 6:40,615,697...40,627,997
Ensembl chr 6:41,923,872...41,936,198 		JBrowse link
G WNT16 Wnt family member 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:113,338,322...113,354,002
Ensembl chr 7:126,025,337...126,041,057 		JBrowse link
G WNT5A Wnt family member 5A acts_upstream_of ISO (MGI:4820702|PMID:20032469) BHF-UCL PMID:20032469 MGI:4820702 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051 		JBrowse link
G WNT7A Wnt family member 7A ISO RGD PMID:18567805 RGD:4107045 NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386 		JBrowse link
G WNT7B Wnt family member 7B ISO RGD PMID:18177422 RGD:2292645 Ensembl chr22:44,988,647...45,044,841 JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606 		JBrowse link
G ZNF622 zinc finger protein 622 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,753,135...16,767,378
Ensembl chr 5:16,591,135...16,605,842 		JBrowse link
positive regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:18584881 RGD:2303073 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,489,263...1,491,391
Ensembl chr19:2,451,837...2,453,992 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:60,695,307...60,696,860
Ensembl chr 9:88,740,411...88,741,958 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in ISO (MGI:5751611|PMID:26774823) UniProt PMID:26774823 MGI:5751611 NCBI chr 8:92,767,401...92,785,955 JBrowse link
G HAND2 heart and neural crest derivatives expressed 2 involved_in ISO (PMID:24161931) BHF-UCL PMID:24161931 NCBI chr 4:165,755,000...165,758,735 JBrowse link
G IL1B interleukin 1 beta involved_in ISO (MGI:5902681|PMID:20739563) ARUK-UCL PMID:20739563 MGI:5902681 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G LEP leptin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519 		JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1353859|PMID:10700190) MGI
Ensembl		 PMID:10700190 GO_REF:0000107 MGI:1353859 NCBI chr17:57,702,242...57,776,601
Ensembl chr17:62,858,635...62,922,874 		JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:20716917 RGD:10412640 NCBI chr 6:134,316,841...134,582,843
Ensembl chr 6:138,406,398...138,641,727 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:5529574|PMID:23994610) MGI PMID:23994610 MGI:5529574 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,318,455...10,428,469 JBrowse link
G MINK1 misshapen like kinase 1 involved_in ISO (MGI:1354211|PMID:10708748) UniProt PMID:10708748 MGI:1354211 NCBI chr17:4,879,851...4,944,374
Ensembl chr17:4,868,620...4,932,789 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:81,917,167...81,932,589 JBrowse link
G OPRK1 opioid receptor kappa 1 ISO RGD PMID:16648139 RGD:9831415 NCBI chr 8:49,650,844...49,677,494
Ensembl chr 8:47,029,313...47,056,577 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:104,688,464...104,759,669
Ensembl chr 5:110,497,245...110,541,354 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISO PMID:23483889 BHF-UCL PMID:23483889 RGD:10047341 NCBI chr19:46,691,795...46,705,179
Ensembl chr19:55,610,938...55,623,135 		JBrowse link
G RELL1 RELT like 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 4:31,939,962...32,013,856
Ensembl chr 4:37,798,632...37,869,421 		JBrowse link
G RELL2 RELT like 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 5:136,997,811...137,002,695
Ensembl chr 5:143,110,359...143,118,157 		JBrowse link
G SASH1 SAM and SH3 domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23776175) MGI
Ensembl		 PMID:23776175 GO_REF:0000107 NCBI chr 6:146,154,178...146,368,101
Ensembl chr 6:150,863,677...151,075,816 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:55,204,203...55,501,033
Ensembl chr2B:172,674,514...172,970,063 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (PMID:18386220) UniProt PMID:18386220 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
G XDH xanthine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556 		JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,020,908...69,042,065
Ensembl chr 3:70,387,581...70,408,909 		JBrowse link
G CARD9 caspase recruitment domain family member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3697751|PMID:17187069)
(PMID:17187069)		 MGI
Ensembl		 PMID:17187069 GO_REF:0000107 MGI:3697751 NCBI chr 9:107,432,709...107,446,271
Ensembl chr 9:136,416,279...136,424,756 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19211730 RGD:5130956 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:37,130,386...37,184,587
Ensembl chr2A:37,895,814...37,941,686 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:17161379 RGD:5508698 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,654,172...35,659,115
Ensembl chr12:36,435,221...36,440,132 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:15671867 RGD:1358666 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:12629164 PMID:15671867 RGD:1358666 RGD:1626685 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL26 interleukin 26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,710,066...65,734,659
Ensembl chr12:68,495,807...68,519,637 		JBrowse link
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:176,491,264...176,514,719
Ensembl chr 1:180,794,646...180,818,853 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor NOT ISO RGD PMID:16222076 RGD:1599289 NCBI chr 1:179,792,116...179,800,377
Ensembl chr 1:184,080,570...184,104,815 		JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 ISO RGD PMID:12024021 RGD:2302280 NCBI chr22:30,846,613...30,857,737
Ensembl chr22:49,957,769...49,966,986 		JBrowse link
G MID1 midline 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:3,075,834...3,463,845
Ensembl chr  X:10,328,476...10,459,284 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
(PMID:17187069)		 MGI
Ensembl		 PMID:17187069 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G PDCD10 programmed cell death 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:164,703,909...164,755,085
Ensembl chr 3:172,760,923...172,811,430 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2176424|PMID:11894097)
(MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938)		 MGI
Ensembl		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 MGI:2176422 MGI:2176424 MGI:3775161 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,258,376...5,283,747
Ensembl chr17:5,247,307...5,270,817 		JBrowse link
G SEMA4C semaphorin 4C involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:102,443,333...102,455,176
Ensembl chr2A:97,780,242...97,787,341 		JBrowse link
G STK25 serine/threonine kinase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:128,766,408...128,779,939
Ensembl chr2B:247,560,624...247,574,249 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,222,725...27,385,713
Ensembl chr17:27,746,797...27,840,623 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,347,229...30,366,743 JBrowse link
G TAOK3 TAO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:115,730,619...115,954,149
Ensembl chr12:119,109,642...119,226,502 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
positive regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G RNF13 ring finger protein 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:146,828,951...146,983,613
Ensembl chr 3:154,408,822...154,563,298 		JBrowse link
regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:63,586,062...63,605,213
Ensembl chr 8:65,247,950...65,266,511 		JBrowse link
G EGFR epidermal growth factor receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615 		JBrowse link
G EPHB1 EPH receptor B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:131,841,459...132,309,082
Ensembl chr 3:139,313,387...139,776,802 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265 		JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 involved_in ISO PMID:11152698 UniProt PMID:11152698 RGD:8554109 NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (PMID:14966141) UniProt PMID:14966141 Ensembl chr2A:102,750,221...102,945,263 JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:45,839,754...45,860,615
Ensembl chr11:46,332,159...46,352,010 		JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:30,846,613...30,857,737
Ensembl chr22:49,957,769...49,966,986 		JBrowse link
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 involved_in ISO (MGI:1352260|PMID:10629060) UniProt PMID:10629060 MGI:1352260 NCBI chr16:327,995...392,691
Ensembl chr16:1,759,171...1,821,246 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:17348686 RGD:2298766 NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135 		JBrowse link
G MDFI MyoD family inhibitor involved_in ISO (MGI:4441137|PMID:12192039) UniProt PMID:12192039 MGI:4441137 NCBI chr 6:41,222,123...41,239,474
Ensembl chr 6:42,527,805...42,545,030 		JBrowse link
G MDFIC MyoD family inhibitor domain containing involved_in ISO (PMID:12192039) UniProt PMID:12192039 NCBI chr 7:106,886,481...106,983,546
Ensembl chr 7:119,584,817...119,678,614 		JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 involved_in ISO (PMID:17386267) UniProt PMID:17386267 NCBI chr18:56,084,851...56,338,551 JBrowse link
G RAP2A RAP2A, member of RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:78,595,330...78,629,012
Ensembl chr13:97,751,799...97,785,194 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:10811109 RGD:11534984 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:141,386,060...141,530,993
Ensembl chr 5:147,401,188...147,545,703 		JBrowse link
G SH3RF3 SH3 domain containing ring finger 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr2A:92,137,951...92,519,627
Ensembl chr2A:110,848,452...111,219,915 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 NOT|involved_in ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587 		JBrowse link
G TRAF2 TNF receptor associated factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2680840|PMID:12958312) MGI
Ensembl
InterPro		 PMID:12958312 GO_REF:0000002 GO_REF:0000107 MGI:2680840 NCBI chr 9:107,938,935...107,984,797
Ensembl chr 9:136,917,358...136,955,331 		JBrowse link
G ULK4 unc-51 like kinase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24284070) MGI
Ensembl		 PMID:24284070 GO_REF:0000107 NCBI chr 3:41,152,261...41,864,865
Ensembl chr 3:41,568,907...42,121,959 		JBrowse link
G ZNF274 zinc finger protein 274 involved_in ISO (MGI:3579762|PMID:15668238) UniProt PMID:15668238 MGI:3579762 NCBI chr19:55,163,153...55,221,933
Ensembl chr19:64,017,183...64,048,097 		JBrowse link
regulation of p38MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G CAV3 caveolin 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4946902|PMID:21182936) MGI
Ensembl		 PMID:21182936 GO_REF:0000107 MGI:4946902 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G HGF hepatocyte growth factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5529574|PMID:23994610) MGI
Ensembl		 PMID:23994610 GO_REF:0000107 MGI:5529574 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G PER1 period circadian regulator 1 involved_in ISO PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr17:43,502,080...43,518,098
Ensembl chr17:48,234,360...48,250,391 		JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 involved_in ISO (PMID:17386267) UniProt PMID:17386267 NCBI chr18:56,084,851...56,338,551 JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 NOT|involved_in ISO (PMID:19933860) UniProt PMID:19933860 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 NOT|involved_in ISO (MGI:5440106|PMID:23021218) UniProt PMID:23021218 MGI:5440106 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
G ULK4 unc-51 like kinase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24284070) MGI
Ensembl		 PMID:24284070 GO_REF:0000107 NCBI chr 3:41,152,261...41,864,865
Ensembl chr 3:41,568,907...42,121,959 		JBrowse link
regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAS Fas cell surface death receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISO (MGI:5318033|PMID:12135612) BHF-UCL PMID:12135612 MGI:5318033 NCBI chr15:11,213,870...11,230,619 JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (MGI:5009198|PMID:10945608) BHF-UCL PMID:10945608 MGI:5009198 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IEA UniProt GO_REF:0000117 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G NBR1 NBR1 autophagy cargo receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,119,638...14,197,827
Ensembl chr17:14,351,229...14,390,597 		JBrowse link
G PRDX1 peroxiredoxin 1 acts_upstream_of_or_within ISO (MGI:3695235|PMID:16880205) MGI PMID:16880205 MGI:3695235 NCBI chr 1:44,813,508...44,824,430
Ensembl chr 1:46,171,453...46,182,018 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15365
    cellular process 14212
      regulation of cellular process 9681
        regulation of cellular response to stress 680
          regulation of stress-activated protein kinase signaling cascade 197
            negative regulation of stress-activated protein kinase signaling cascade + 49
            positive regulation of stress-activated protein kinase signaling cascade + 130
            regulation of stress-activated MAPK cascade + 194
Path 2
Term Annotations click to browse term
  biological_process 15365
    biological regulation 11000
      regulation of biological process 10399
        regulation of cellular process 9681
          signal transduction 4977
            intracellular signal transduction 2382
              regulation of intracellular signal transduction 1613
                regulation of stress-activated protein kinase signaling cascade 197
                  negative regulation of stress-activated protein kinase signaling cascade + 49
                  positive regulation of stress-activated protein kinase signaling cascade + 130
                  regulation of stress-activated MAPK cascade + 194
paths to the root