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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to hydrogen peroxide
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Accession:GO:0070301 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.


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cellular response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase JBrowse link 2 31,688,244 31,807,093 RGD:2290270
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) JBrowse link 6 34,303,930 34,317,489 RGD:2290270
G Ankzf1 ankyrin repeat and zinc finger domain containing 1 JBrowse link 1 75,192,160 75,199,387 RGD:2290270
G Anxa1 annexin A1 JBrowse link 19 20,373,434 20,390,671 RGD:2290270
G Apex1 apurinic/apyrimidinic endonuclease 1 JBrowse link 14 50,924,949 50,927,188 RGD:2290270
G Aqp1 aquaporin 1 JBrowse link 6 55,336,299 55,348,555 RGD:2290270
G Axl AXL receptor tyrosine kinase JBrowse link 7 25,756,500 25,788,924 RGD:2290270
G Bnip3 BCL2/adenovirus E1B interacting protein 3 JBrowse link 7 138,890,836 138,909,506 RGD:2290270
G Capn1 calpain 1 JBrowse link 19 5,988,545 6,015,825 RGD:2290270
G Cdkn2a cyclin dependent kinase inhibitor 2A JBrowse link 4 89,274,473 89,294,619 RGD:2290270
G Cfl1 cofilin 1, non-muscle JBrowse link 19 5,490,455 5,494,031 RGD:2290270
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:2290270
G Ect2 ect2 oncogene JBrowse link 3 27,097,222 27,154,253 RGD:2290270
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 6 47,530,274 47,595,270 RGD:2290270
G Fabp1 fatty acid binding protein 1, liver JBrowse link 6 71,199,879 71,205,034 RGD:2290270
G Fxn frataxin JBrowse link 19 24,259,545 24,280,590 RGD:2290270
G Hdac2 histone deacetylase 2 JBrowse link 10 36,974,297 37,001,889 RGD:2290270
G Hdac6 histone deacetylase 6 JBrowse link X 7,930,116 7,948,047 RGD:2290270
G Hsf1 heat shock factor 1 JBrowse link 15 76,477,362 76,501,155 RGD:2290270
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:2290270
G Impact impact, RWD domain protein JBrowse link 18 12,954,690 12,992,950 RGD:2290270
G Kdm6b KDM1 lysine (K)-specific demethylase 6B JBrowse link 11 69,398,508 69,420,367 RGD:2290270
G Lcn2 lipocalin 2 JBrowse link 2 32,384,637 32,387,739 RGD:2290270
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 10 19,934,101 20,142,750 RGD:2290270
G Mapk13 mitogen-activated protein kinase 13 JBrowse link 17 28,769,286 28,778,704 RGD:2290270
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 11 61,488,812 61,494,267 RGD:2290270
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 14 33,377,898 33,447,353 RGD:2290270
G Net1 neuroepithelial cell transforming gene 1 JBrowse link 13 3,882,018 3,918,220 RGD:2290270
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:2290270
G Nqo1 NAD(P)H dehydrogenase, quinone 1 JBrowse link 8 107,388,225 107,403,205 RGD:2290270
G Oser1 oxidative stress responsive serine rich 1 JBrowse link 2 163,405,822 163,419,470 RGD:2290270
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Pax2 paired box 2 JBrowse link 19 44,746,601 44,838,269 RGD:2290270
G Pcgf2 polycomb group ring finger 2 JBrowse link 11 97,688,821 97,702,434 RGD:2290270
G Pdgfrb platelet derived growth factor receptor, beta polypeptide JBrowse link 18 61,045,127 61,085,067 RGD:2290270
G Plekha1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 JBrowse link 7 130,860,551 130,913,494 RGD:2290270
G Ppif peptidylprolyl isomerase F (cyclophilin F) JBrowse link 14 25,693,574 25,700,468 RGD:2290270
G Prkcd protein kinase C, delta JBrowse link 14 30,595,353 30,626,414 RGD:2290270
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:2290270
G Rhob ras homolog family member B JBrowse link 12 8,497,661 8,500,009 RGD:2290270
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 JBrowse link 13 34,002,225 34,035,170 RGD:2290270
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 14 55,784,995 55,788,857 RGD:2290270
G Rps3 ribosomal protein S3 JBrowse link 7 99,477,896 99,483,709 RGD:2290270
G Setx senataxin JBrowse link 2 29,123,588 29,182,471 RGD:2290270
G Sirpa signal-regulatory protein alpha JBrowse link 2 129,591,042 129,632,228 RGD:2290270
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:2290270
G Smpd3 sphingomyelin phosphodiesterase 3, neutral JBrowse link 8 106,252,548 106,337,965 RGD:2290270
G Sphk1 sphingosine kinase 1 JBrowse link 11 116,530,836 116,536,675 RGD:2290270
G Src Rous sarcoma oncogene JBrowse link 2 157,423,906 157,471,838 RGD:2290270
G Stat6 signal transducer and activator of transcription 6 JBrowse link 10 127,642,955 127,660,987 RGD:2290270
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 JBrowse link 10 19,000,910 19,015,410 RGD:2290270
G Top2b topoisomerase (DNA) II beta JBrowse link 14 16,365,206 16,430,787 RGD:2290270
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 JBrowse link 9 8,543,867 8,680,752 RGD:2290270
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 10 77,907,722 77,969,909 RGD:2290270
G Zfp277 zinc finger protein 277 JBrowse link 12 40,315,046 40,445,790 RGD:2290270
G Zfp580 zinc finger protein 580 JBrowse link 7 5,038,519 5,053,723 RGD:2290270
cell death in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf112 ring finger protein 112 JBrowse link 11 61,448,417 61,454,188 RGD:2290270
G Sigmar1 sigma non-opioid intracellular receptor 1 JBrowse link 4 41,738,493 41,741,359 RGD:2290270
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdcd10 programmed cell death 10 JBrowse link 3 75,516,490 75,556,852 RGD:2290270
G Stk25 serine/threonine kinase 25 (yeast) JBrowse link 1 93,620,751 93,654,216 RGD:2290270
negative regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epor erythropoietin receptor JBrowse link 9 21,958,897 21,963,576 RGD:2290270
G Gpr37 G protein-coupled receptor 37 JBrowse link 6 25,668,523 25,689,980 RGD:2290270
G Gpr37l1 G protein-coupled receptor 37-like 1 JBrowse link 1 135,160,250 135,167,681 RGD:2290270
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 15 91,672,791 91,816,124 RGD:2290270
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:2290270
G Ngb neuroglobin JBrowse link 12 87,097,531 87,102,539 RGD:2290270
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) JBrowse link 8 105,276,145 105,281,939 RGD:2290270
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Pde8a phosphodiesterase 8A JBrowse link 7 81,213,265 81,334,535 RGD:2290270
G Psap prosaposin JBrowse link 10 60,277,628 60,302,600 RGD:2290270
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 11 120,635,712 120,643,769 RGD:2290270
G Rnf146 ring finger protein 146 JBrowse link 10 29,344,176 29,362,442 RGD:2290270
G Txn1 thioredoxin 1 JBrowse link 4 57,943,373 57,956,411 RGD:2290270
negative regulation of hydrogen peroxide-induced neuron death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxo7 F-box protein 7 JBrowse link 10 86,020,449 86,051,873 RGD:2290270
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:2290270
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 4 48,045,078 48,086,447 RGD:2290270
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Rack1 receptor for activated C kinase 1 JBrowse link 11 48,800,360 48,806,241 RGD:2290270
G Reg3b regenerating islet-derived 3 beta JBrowse link 6 78,370,885 78,373,466 RGD:2290270
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Pink1 PTEN induced putative kinase 1 JBrowse link 4 138,313,409 138,326,296 RGD:2290270
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glrx glutaredoxin JBrowse link 13 75,839,885 75,850,151 RGD:2290270
G Hgf hepatocyte growth factor JBrowse link 5 16,553,495 16,619,439 RGD:2290270
G Hk3 hexokinase 3 JBrowse link 13 55,005,985 55,021,475 RGD:2290270
G Met met proto-oncogene JBrowse link 6 17,463,349 17,573,980 RGD:2290270
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsph1 heat shock 105kDa/110kDa protein 1 JBrowse link 5 149,616,843 149,636,498 RGD:2290270
G Pink1 PTEN induced putative kinase 1 JBrowse link 4 138,313,409 138,326,296 RGD:2290270
G Trap1 TNF receptor-associated protein 1 JBrowse link 16 4,039,971 4,077,840 RGD:2290270
positive regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 6 98,925,342 99,522,746 RGD:2290270
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 JBrowse link 13 34,002,225 34,035,170 RGD:2290270
positive regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Endog endonuclease G JBrowse link 2 30,171,408 30,174,069 RGD:2290270
G Foxo3 forkhead box O3 JBrowse link 10 42,181,845 42,276,839 RGD:2290270
G Hdac6 histone deacetylase 6 JBrowse link X 7,930,116 7,948,047 RGD:2290270
G Pawr PRKC, apoptosis, WT1, regulator JBrowse link 10 108,332,189 108,414,391 RGD:2290270
regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stk26 serine/threonine kinase 26 JBrowse link X 50,841,174 50,893,103 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23162
    cellular process 16953
      cellular response to stimulus 8035
        cellular response to chemical stimulus 3171
          cellular response to drug 437
            cellular response to hydrogen peroxide 89
              cell death in response to hydrogen peroxide + 37
              cellular detoxification of hydrogen peroxide 0
              positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide 0
Path 2
Term Annotations click to browse term
  biological_process 23162
    cellular process 16953
      cellular response to stimulus 8035
        cellular response to chemical stimulus 3171
          cellular response to chemical stress 333
            cellular response to oxidative stress 273
              cellular response to reactive oxygen species 150
                cellular response to hydrogen peroxide 89
                  cell death in response to hydrogen peroxide + 37
                  cellular detoxification of hydrogen peroxide 0
                  positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.