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ONTOLOGY REPORT - ANNOTATIONS

Term:mucus secretion
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Accession:GO:0070254 term browser browse the term
Definition:The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.
Synonyms:exact_synonym: mucus production


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mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of ISO (MGI:3525377|PMID:15630442)
(MGI:3051181|PMID:15240734)
(MGI:3051181|PMID:15240734), (MGI:3525377|PMID:15630442)		 MGI PMID:15240734 PMID:15630442 MGI:3051181 MGI:3525377 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,495...47,072,245 		JBrowse link
G ADORA1 adenosine A1 receptor acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3525377|PMID:15630442) MGI
Ensembl		 PMID:15630442 GO_REF:0000107 MGI:3525377 NCBI chr 9:113,835,279...113,875,899
Ensembl chr 9:113,835,920...113,875,719 		JBrowse link
G ADORA3 adenosine A3 receptor acts_upstream_of ISO (MGI:3051181|PMID:15240734) MGI PMID:15240734 MGI:3051181 NCBI chr 4:108,854,300...108,857,769
Ensembl chr 4:108,814,405...108,873,927 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:86,042,070...86,053,893
Ensembl chr 9:86,039,015...86,053,857 		JBrowse link
G ANO1 anoctamin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:3,202,269...3,373,409
Ensembl chr 2:3,202,274...3,373,411 		JBrowse link
G ATG5 autophagy related 5 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5548044|PMID:24185898) MGI
Ensembl		 PMID:24185898 GO_REF:0000107 MGI:5548044 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,453 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of ISO (MGI:5548044|PMID:24185898) MGI PMID:24185898 MGI:5548044 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,660 		JBrowse link
G CYBA cytochrome b-245 alpha chain acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5548044|PMID:24185898) MGI
Ensembl		 PMID:24185898 GO_REF:0000107 MGI:5548044 NCBI chr 6:1,015,212...1,021,422
Ensembl chr 6:1,015,154...1,021,418 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:6100817|PMID:27959908) MGI PMID:27959908 MGI:6100817 NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta acts_upstream_of ISO (MGI:5548044|PMID:24185898) MGI PMID:24185898 MGI:5548044 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,077 		JBrowse link
G P2RY2 purinergic receptor P2Y2 acts_upstream_of ISO (MGI:3833522|PMID:17728398) MGI PMID:17728398 MGI:3833522 NCBI chr 9:7,672,294...7,695,085
Ensembl chr 9:7,672,401...7,695,163 		JBrowse link
G PRKCE protein kinase C epsilon acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3833522|PMID:17728398) MGI
Ensembl		 PMID:17728398 GO_REF:0000107 MGI:3833522 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,909,020 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:6478086|PMID:22419116) Ensembl
Ensembl
MGI		 PMID:22419116 GO_REF:0000107 MGI:6478086 NCBI chr 3:22,832,259...22,902,592
Ensembl chr 3:22,832,262...22,902,063 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:77,483,997...77,541,557
Ensembl chr 1:77,480,926...77,541,210 		JBrowse link
G VAMP2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:22144578) UniProt PMID:22144578 NCBI chr12:53,378,407...53,382,243 JBrowse link
G VAMP3 vesicle associated membrane protein 3 NOT|involved_in ISO (PMID:22144578) UniProt PMID:22144578 NCBI chr 6:68,473,921...68,482,438 JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr 3:59,187,900...59,193,165 JBrowse link
negative regulation of mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3051181|PMID:15240734), (MGI:3525377|PMID:15630442)
(MGI:3525377|PMID:15630442)		 Ensembl
MGI		 PMID:15240734 PMID:15630442 GO_REF:0000107 MGI:3051181 MGI:3525377 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,495...47,072,245 		JBrowse link
G ADORA1 adenosine A1 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3525377|PMID:15630442) Ensembl
Ensembl
MGI		 PMID:15630442 GO_REF:0000107 MGI:3525377 NCBI chr 9:113,835,279...113,875,899
Ensembl chr 9:113,835,920...113,875,719 		JBrowse link
positive regulation of mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA3 adenosine A3 receptor acts_upstream_of_or_within ISO (MGI:3051181|PMID:15240734) MGI PMID:15240734 MGI:3051181 NCBI chr 4:108,854,300...108,857,769
Ensembl chr 4:108,814,405...108,873,927 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:53,292,530...53,302,850
Ensembl chr12:53,292,524...53,302,993 		JBrowse link
G ATG5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5548044|PMID:24185898) Ensembl
Ensembl
MGI		 PMID:24185898 GO_REF:0000107 MGI:5548044 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,453 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:5548044|PMID:24185898) MGI PMID:24185898 MGI:5548044 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,660 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5548044|PMID:24185898) Ensembl
Ensembl
MGI		 PMID:24185898 GO_REF:0000107 MGI:5548044 NCBI chr 6:1,015,212...1,021,422
Ensembl chr 6:1,015,154...1,021,418 		JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:29183867 RGD:38676259 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,478,882 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta acts_upstream_of_or_within ISO (MGI:5548044|PMID:24185898) MGI PMID:24185898 MGI:5548044 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,077 		JBrowse link
G P2RY2 purinergic receptor P2Y2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3833522|PMID:17728398) InterPro
InterPro
MGI		 PMID:17728398 GO_REF:0000002 MGI:3833522 NCBI chr 9:7,672,294...7,695,085
Ensembl chr 9:7,672,401...7,695,163 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3833522|PMID:17728398) Ensembl
Ensembl
MGI		 PMID:17728398 GO_REF:0000107 MGI:3833522 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,909,020 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11991626 PMID:18254372 RGD:10003046 RGD:10003093 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552 		JBrowse link
G SYTL2 synaptotagmin like 2 involved_in ISO (MGI:3693417|PMID:16716193) UniProt PMID:16716193 MGI:3693417 NCBI chr 9:19,617,287...19,763,439
Ensembl chr 9:19,617,291...19,734,636 		JBrowse link
regulation of mucus secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP6 NLR family pyrin domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5577214|PMID:24581500) Ensembl
Ensembl
MGI		 PMID:24581500 GO_REF:0000107 MGI:5577214 NCBI chr 2:90,001...97,441
Ensembl chr 2:90,027...97,439 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17268
    multicellular organismal process 8456
      secretion by tissue 59
        mucus secretion 22
          negative regulation of mucus secretion 2
          positive regulation of mucus secretion 11
          regulation of mucus secretion + 14
Path 2
Term Annotations click to browse term
  biological_process 17268
    localization 5284
      establishment of localization 4649
        transport 4485
          secretion 1112
            body fluid secretion 127
              mucus secretion 22
                negative regulation of mucus secretion 2
                positive regulation of mucus secretion 11
                regulation of mucus secretion + 14
paths to the root