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ONTOLOGY REPORT - ANNOTATIONS


Term:actin-mediated cell contraction
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Accession:GO:0070252 term browser browse the term
Definition:The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.


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actin-mediated cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin alpha cardiac muscle 1 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) MGI PMID:22750946 MGI:5468414 NCBI chrNW_004936673:1,092,700...1,098,256 JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISO (PMID:18469192), (PMID:22728127) UniProt PMID:18469192 PMID:22728127 NCBI chrNW_004936530:8,854,266...8,862,127 JBrowse link
G Myh2 myosin heavy chain 2 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) MGI PMID:22750946 MGI:5468414 NCBI chrNW_004936595:3,391,179...3,398,610 JBrowse link
G Parva parvin alpha involved_in ISO (MGI:4368016|PMID:19798050) UniProt PMID:19798050 MGI:4368016 NCBI chrNW_004936528:5,977,909...6,130,814 JBrowse link
G Pdpn podoplanin involved_in ISO (MGI:5614157|PMID:25341788) UniProt PMID:25341788 MGI:5614157 NCBI chrNW_004936474:1,751,159...1,779,011 JBrowse link
actin-myosin filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin alpha cardiac muscle 1 involved_in ISO (PMID:19799913) BHF-UCL PMID:19799913 NCBI chrNW_004936673:1,092,700...1,098,256 JBrowse link
apical constriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc88c coiled-coil domain containing 88C involved_in ISO (PMID:30948426) UniProt PMID:30948426 NCBI chrNW_004936488:18,288,504...18,402,125 JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 acts_upstream_of_or_within ISO (MGI:4438998|PMID:20103536) MGI PMID:20103536 MGI:4438998 NCBI chrNW_004936469:50,329,564...50,443,532 JBrowse link
G Frmd6 FERM domain containing 6 acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chrNW_004936495:13,969,753...14,060,946 JBrowse link
G Pard3 par-3 family cell polarity regulator acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chrNW_004936574:2,472,064...3,013,590 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chrNW_004936550:730,462...874,601 JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276), (PMID:18832177), (PMID:21859974)
(MGI:5427070|PMID:21859974)
BHF-UCL PMID:17242276 PMID:18832177 PMID:21859974 MGI:5427070 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:18313602) BHF-UCL PMID:18313602 NCBI chrNW_004936499:5,557,076...5,558,467 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251) BHF-UCL PMID:12522251 NCBI chrNW_004936794:707,122...994,206 JBrowse link
G Nup155 nucleoporin 155 acts_upstream_of_or_within ISO (MGI:3839697|PMID:19070573) MGI PMID:19070573 MGI:3839697 NCBI chrNW_004936518:4,635,970...4,688,669 JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO (PMID:21051419) BHF-UCL PMID:21051419 NCBI chrNW_004936542:8,082,487...8,106,154 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:15454078) BHF-UCL PMID:15454078 NCBI chrNW_004936606:2,168,104...2,867,560 JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in ISO (PMID:21131953) BHF-UCL PMID:21131953 NCBI chrNW_004936473:4,164,633...4,479,866 JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chrNW_004936490:11,093,600...11,157,756 JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO (PMID:25527503) BHF-UCL PMID:25527503 NCBI chrNW_004936734:577,656...1,027,412 JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chrNW_004936690:417,907...627,025 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:10400998) BHF-UCL PMID:10400998 NCBI chrNW_004936500:7,998,464...8,007,848 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) BHF-UCL PMID:10219239 NCBI chrNW_004936500:8,067,009...8,072,383 JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 involved_in ISO (PMID:11371347) BHF-UCL PMID:11371347 NCBI chrNW_004936655:3,447,026...3,459,569 JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chrNW_004936607:3,458,406...3,530,066 JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chrNW_004936469:13,194,769...13,345,979 JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO (PMID:19808477) BHF-UCL PMID:19808477 NCBI chrNW_004936570:1,187,916...1,195,423 JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in ISO (PMID:19808477) BHF-UCL PMID:19808477 NCBI chrNW_004936542:3,262,161...3,274,545 JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO (PMID:21051419) BHF-UCL PMID:21051419 NCBI chrNW_004936542:8,082,487...8,106,154 JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISO (PMID:17592081) BHF-UCL PMID:17592081 NCBI chrNW_004936542:3,236,238...3,252,550 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
ISO (PMID:21895525)
(MGI:6402838|PMID:32109384)
BHF-UCL
MGI
PMID:21895525 PMID:32109384 MGI:6402838 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2d calcium/calmodulin dependent protein kinase II delta involved_in ISO PMID:12676814 BHF-UCL PMID:12676814 RGD:8656014 NCBI chrNW_004936563:4,226,412...4,526,139 JBrowse link
G Gsn gelsolin involved_in ISO (MGI:6450443|PMID:30568254) BHF-UCL PMID:30568254 MGI:6450443 NCBI chrNW_004936487:9,749,755...9,802,787 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (MGI:6450443|PMID:30568254) BHF-UCL PMID:30568254 MGI:6450443 NCBI chrNW_004936566:3,924,013...3,951,052 JBrowse link
G Sgcd sarcoglycan delta acts_upstream_of_or_within ISO (MGI:1343715|PMID:10481911) MGI PMID:10481911 MGI:1343715 NCBI chrNW_004936515:6,278,631...6,908,193 JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO RGD PMID:20868366 RGD:7349316 NCBI chrNW_004936474:11,460,266...11,517,420 JBrowse link
cytoplasmic actin-based contraction involved in cell motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Limch1 LIM and calponin homology domains 1 involved_in ISO (PMID:28228547) CACAO PMID:28228547 NCBI chrNW_004936482:8,620,543...8,932,731 JBrowse link
G Shtn1 shootin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chrNW_004936486:6,786,037...6,867,221 JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15342783) UniProt PMID:15342783 NCBI chrNW_004936569:914,511...938,481 JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:17224476) BHF-UCL PMID:17224476 NCBI chrNW_004936606:2,168,104...2,867,560 JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISO (PMID:17224476) BHF-UCL PMID:17224476 NCBI chrNW_004936520:8,951,994...9,164,039 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj5 potassium inwardly rectifying channel subfamily J member 5 involved_in ISO (PMID:20560207) BHF-UCL PMID:20560207 NCBI chrNW_004936572:3,344,942...3,373,690 JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:5292192 NCBI chrNW_004937043:133,981...269,593 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251 PMID:25786344 NCBI chrNW_004936794:707,122...994,206 JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) BHF-UCL PMID:9354802 NCBI chrNW_004936500:7,998,464...8,007,848 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) BHF-UCL PMID:10219239 NCBI chrNW_004936500:8,067,009...8,072,383 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chrNW_004936527:6,380,222...6,412,390 JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 involved_in ISO (PMID:20558321) BHF-UCL PMID:20558321 NCBI chrNW_004936548:5,125,583...5,132,490 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chrNW_004936794:707,122...994,206 JBrowse link
muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101972165 myosin-7 involved_in ISO (PMID:16088376), (PMID:8514894) HGNC-UCL PMID:8514894 PMID:16088376 NCBI chrNW_004936722:967,443...991,530 JBrowse link
G Myh8 myosin heavy chain 8 involved_in ISO (PMID:17041932) BHF-UCL PMID:17041932 NCBI chrNW_004936595:3,278,829...3,307,134 JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in ISO (PMID:12186860), (PMID:15923195) UniProt PMID:12186860 PMID:15923195 NCBI chrNW_004936567:3,052,167...3,069,077 JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chrNW_004936471:23,643,645...23,670,775 JBrowse link
myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epdr1 ependymin related 1 involved_in ISO (PMID:27245865) UniProt PMID:27245865 NCBI chrNW_004936478:13,270,227...13,296,711 JBrowse link
negative regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos1 nitric oxide synthase 1 ISO RGD PMID:10727442 RGD:13824993 NCBI chrNW_004936558:5,162,471...5,302,488 JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) BHF-UCL PMID:22987075 NCBI chrNW_004936498:3,477,313...3,487,580 JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 ISO RGD PMID:17543276 RGD:10398727 NCBI chrNW_004936597:1,735,589...1,751,628 JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in ISO (MGI:5583915|PMID:24836577) ARUK-UCL PMID:24836577 MGI:5583915 NCBI chrNW_004936469:44,128,308...44,185,739 JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23954346 RGD:10003031 NCBI chrNW_004936664:3,093,258...3,124,473 JBrowse link
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:19443576 RGD:7205486 NCBI chrNW_004936694:2,702,224...2,724,574 JBrowse link
G Strit1 small transmembrane regulator of ion transport 1 involved_in ISO (MGI:6304509|PMID:30299255) UniProt PMID:30299255 MGI:6304509
positive regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle ISO RGD PMID:24204762 RGD:12879446 NCBI chrNW_004936735:266,918...283,858 JBrowse link
positive regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:19239477 RGD:10045899 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 involved_in ISO (PMID:25281747) BHF-UCL PMID:25281747 NCBI chrNW_004936623:1,065,260...1,079,918 JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:12571597)
(MGI:2449848|PMID:12571597)
BHF-UCL PMID:12571597 MGI:2449848 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Gja5 gap junction protein alpha 5 involved_in ISO (PMID:23348765) BHF-UCL PMID:23348765 NCBI chrNW_004936867:269,477...279,549 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in ISO (PMID:18093912) BHF-UCL PMID:18093912 NCBI chrNW_004936621:2,247,082...2,374,407 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in ISO PMID:9851937 BHF-UCL PMID:9851937 RGD:10047146 NCBI chrNW_004936558:3,300,941...3,357,595 JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:17060380) BHF-UCL PMID:17060380 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISO (MGI:5437408|PMID:21817159) BHF-UCL PMID:21817159 MGI:5437408 NCBI chrNW_004936513:8,419,588...8,911,010 JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in ISO (PMID:16407510) BHF-UCL PMID:16407510 NCBI chrNW_004936471:32,527,551...32,570,548 JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) BHF-UCL PMID:21621375 NCBI chrNW_004936595:1,513,855...1,515,300 JBrowse link
regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:19525381 RGD:2317914 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:19525381 PMID:22216755 RGD:2317914 RGD:6893639 NCBI chrNW_004936486:4,400,467...4,401,588 JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in ISO PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chrNW_004936494:6,744,923...7,228,670 JBrowse link
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276)
(MGI:3771114|PMID:17242276)
BHF-UCL PMID:17242276 MGI:3771114 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:15629895 RGD:6903236 NCBI chrNW_004936627:1,555,151...1,584,370 JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 ISO RGD PMID:17442282 RGD:6903343 NCBI chrNW_004936740:489,357...514,235 JBrowse link
G Casq2 calsequestrin 2 involved_in ISO PMID:17569730 BHF-UCL PMID:17569730 RGD:2314601 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Fxyd1 FXYD domain containing ion transport regulator 1 ISO RGD PMID:14684371 RGD:9685468 NCBI chrNW_004936570:1,117,083...1,121,059 JBrowse link
G Gata4 GATA binding protein 4 ISO RGD PMID:21702924 RGD:7207043 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 ISO RGD PMID:22426100 RGD:7247430 NCBI chrNW_004936655:3,447,026...3,459,569 JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO (MGI:5286798|PMID:21670503) BHF-UCL PMID:21670503 MGI:5286798 NCBI chrNW_004936591:5,152,491...5,666,728 JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO (MGI:5286798|PMID:21670503), (MGI:5442270|PMID:21903937)
PMID:19801680
RGD
BHF-UCL
PMID:19801680 PMID:21670503 PMID:21903937 MGI:5286798 MGI:5442270 RGD:7327160 NCBI chrNW_004936480:8,123,437...9,235,586 JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO (MGI:3655311|PMID:8620604) MGI PMID:8620604 MGI:3655311 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
ISO (PMID:22529811)
(MGI:3695100|PMID:16172272)
BHF-UCL
MGI
PMID:16172272 PMID:22529811 MGI:3695100 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
G Sri sorcin involved_in ISO (PMID:12754254), (PMID:17130302) BHF-UCL PMID:12754254 PMID:17130302 NCBI chrNW_004936763:715,884...728,548 JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO (PMID:12663264) UniProt PMID:12663264 NCBI chrNW_004936555:7,240,649...7,251,668 JBrowse link
G Sumo1 small ubiquitin like modifier 1 involved_in ISO (MGI:5292424|PMID:21900893) BHF-UCL PMID:21900893 MGI:5292424 NCBI chrNW_004936726:1,402,977...1,413,974 JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylk2 myosin light chain kinase 2 involved_in ISO (PMID:16448786) BHF-UCL PMID:16448786 NCBI chrNW_004936485:18,782,890...18,795,942 JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnc1 troponin C1, slow skeletal and cardiac type involved_in ISO (MGI:3793933|PMID:10747195) BHF-UCL PMID:10747195 MGI:3793933 NCBI chrNW_004936473:3,290,961...3,293,920 JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in ISO PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chrNW_004936567:3,052,167...3,069,077 JBrowse link
regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdpn podoplanin involved_in ISO (MGI:5644359|PMID:25347465) UniProt PMID:25347465 MGI:5644359 NCBI chrNW_004936474:1,751,159...1,779,011 JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:15454078), (PMID:26253506) BHF-UCL PMID:15454078 PMID:26253506 NCBI chrNW_004936606:2,168,104...2,867,560 JBrowse link
G Cav1 caveolin 1 involved_in ISO (MGI:5607357|PMID:25017399) BHF-UCL PMID:25017399 MGI:5607357 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Ctnna3 catenin alpha 3 involved_in ISO (PMID:23136403) BHF-UCL PMID:23136403 NCBI chrNW_004936521:10,482,434...10,936,554 JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISO (MGI:5816439|PMID:25447080) BHF-UCL PMID:25447080 MGI:5816439 NCBI chrNW_004936833:551,989...843,064 JBrowse link
G Dsc2 desmocollin 2 involved_in ISO (PMID:23863954) BHF-UCL PMID:23863954 NCBI chrNW_004936682:2,057,331...2,091,034 JBrowse link
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173 PMID:23381804 NCBI chrNW_004936682:1,676,301...1,725,132 JBrowse link
G LOC101960169 junction plakoglobin involved_in ISO (PMID:17924338) BHF-UCL PMID:17924338 NCBI chrNW_004936490:16,671,176...16,694,552 JBrowse link
G LOC101968918 desmoplakin involved_in ISO (PMID:12373648) BHF-UCL PMID:12373648 NCBI chrNW_004936534:5,029,008...5,076,467 JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chrNW_004936607:3,458,406...3,530,066 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chrNW_004936664:3,093,258...3,124,473 JBrowse link
ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276) BHF-UCL PMID:17242276 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Cav3 caveolin 3 involved_in ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Gja5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:1197846|PMID:9501070) MGI PMID:9501070 MGI:1197846 NCBI chrNW_004936867:269,477...279,549 JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:17967977), (PMID:19666841) BHF-UCL PMID:17967977 PMID:19666841 NCBI chrNW_004936473:22,649,107...22,774,719 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) BHF-UCL PMID:9354802 NCBI chrNW_004936500:7,998,464...8,007,848 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within
ISO (PMID:10219239)
(MGI:3813163|PMID:18603586)
BHF-UCL
MGI
PMID:10219239 PMID:18603586 MGI:3813163 NCBI chrNW_004936500:8,067,009...8,072,383 JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:21493962) BHF-UCL PMID:21493962 NCBI chrNW_004936499:5,557,076...5,558,467 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chrNW_004936527:6,380,222...6,412,390 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chrNW_004936794:707,122...994,206 JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chrNW_004936497:6,106,284...6,318,339 JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chrNW_004936607:3,458,406...3,530,066 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (MGI:3820489|PMID:17872467) BHF-UCL PMID:17872467 MGI:3820489 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20042427)
(MGI:5294649|PMID:19351516)
BHF-UCL
MGI
PMID:19351516 PMID:20042427 MGI:5294649 NCBI chrNW_004936542:8,082,487...8,106,154 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:22529811) BHF-UCL PMID:22529811 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
G Snta1 syntrophin alpha 1 involved_in ISO (PMID:18591664) BHF-UCL PMID:18591664 NCBI chrNW_004936561:7,101,654...7,134,529 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12170
    cellular process 11365
      actin filament-based process 643
        actin filament-based movement 109
          actin-mediated cell contraction 91
            actin-myosin filament sliding + 8
            apical constriction + 5
            cardiac muscle cell contraction + 67
            cytoplasmic actin-based contraction involved in cell motility + 3
            hepatic stellate cell contraction + 2
            myofibroblast contraction + 3
paths to the root