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ONTOLOGY REPORT - ANNOTATIONS


Term:actin-mediated cell contraction
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Accession:GO:0070252 term browser browse the term
Definition:The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.


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actin-mediated cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTC1 actin alpha cardiac muscle 1 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) MGI PMID:22750946 MGI:5468414 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,230...34,795,549
JBrowse link
G EMP2 epithelial membrane protein 2 involved_in IDA (PMID:18469192), (PMID:22728127) UniProt PMID:18469192 PMID:22728127 NCBI chr16:10,528,422...10,580,598
Ensembl chr16:10,528,422...10,580,632
JBrowse link
G MYH2 myosin heavy chain 2 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) MGI PMID:22750946 MGI:5468414 NCBI chr17:10,521,148...10,549,658
Ensembl chr17:10,521,148...10,549,700
JBrowse link
G PARVA parvin alpha involved_in ISS UniProt GO_REF:0000024 NCBI chr11:12,376,441...12,535,356
Ensembl chr11:12,377,563...12,535,356
JBrowse link
G PDPN podoplanin involved_in IBA
ISS
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957
JBrowse link
actin-myosin filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTC1 actin alpha cardiac muscle 1 involved_in IBA
IMP
(PMID:21873635)
(PMID:19799913)
GO_Central
BHF-UCL
PMID:19799913 PMID:21873635 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,230...34,795,549
JBrowse link
apical constriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC88C coiled-coil domain containing 88C involved_in IDA (PMID:30948426) UniProt PMID:30948426 NCBI chr14:91,271,323...91,417,820
Ensembl chr14:91,271,323...91,417,844
JBrowse link
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4438998|PMID:20103536) Ensembl
MGI
PMID:20103536 GO_REF:0000107 MGI:4438998 NCBI chr 2:120,013,032...120,179,119
Ensembl chr 2:120,013,077...120,179,119
JBrowse link
G FRMD6 FERM domain containing 6 acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chr14:51,489,100...51,730,727
Ensembl chr14:51,489,100...51,730,727
JBrowse link
G PARD3 par-3 family cell polarity regulator acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,946,906...21,111,813
JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:17242276), (PMID:18832177), (PMID:21859974) BHF-UCL PMID:17242276 PMID:18832177 PMID:21859974 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in TAS (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJC1 gap junction protein gamma 1 involved_in TAS (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr17:44,794,988...44,831,364
Ensembl chr17:44,798,448...44,830,816
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IMP (PMID:18313602) BHF-UCL PMID:18313602 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:12522251) BHF-UCL PMID:12522251 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G NUP155 nucleoporin 155 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3839697|PMID:19070573) Ensembl
MGI
PMID:19070573 GO_REF:0000107 MGI:3839697 NCBI chr 5:37,288,137...37,371,106
Ensembl chr 5:37,288,137...37,371,106
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IMP (PMID:21051419) BHF-UCL PMID:21051419 NCBI chr11:123,629,187...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in TAS (PMID:23224879) BHF-UCL PMID:23224879 NCBI chr 1:116,372,986...116,410,259
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:15454078) BHF-UCL PMID:15454078 NCBI chr12:1,969,552...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in IMP (PMID:21131953) BHF-UCL PMID:21131953 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,629,625
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IMP (PMID:25527503) BHF-UCL PMID:25527503 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,777
JBrowse link
G FGF12 fibroblast growth factor 12 involved_in NAS (PMID:12401812) BHF-UCL PMID:12401812 NCBI chr 3:192,139,390...192,727,541
Ensembl chr 3:192,139,390...192,767,764
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP (PMID:10400998) BHF-UCL PMID:10400998 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IMP (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IMP (PMID:11371347) BHF-UCL PMID:11371347 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G PKP2 plakophilin 2 involved_in IMP (PMID:22889254) BHF-UCL PMID:22889254 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,755...32,896,777
JBrowse link
G SCN1A sodium voltage-gated channel alpha subunit 1 involved_in IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr 2:165,984,641...166,149,161
Ensembl chr 2:165,984,641...166,149,214
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IBA
IMP
(PMID:21873635)
(PMID:19808477)
GO_Central
BHF-UCL
PMID:19808477 PMID:21873635 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IMP
IBA
(PMID:19808477)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:19808477 PMID:21873635 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IBA
IMP
(PMID:21873635)
(PMID:21051419)
GO_Central
BHF-UCL
PMID:21051419 PMID:21873635 NCBI chr11:123,629,187...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IMP
IBA
(PMID:17592081)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:17592081 PMID:21873635 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:21895525)
(MGI:6402838|PMID:32109384)
BHF-UCL
MGI
PMID:21895525 PMID:32109384 MGI:6402838 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in ISS (PMID:12676814) BHF-UCL PMID:12676814 NCBI chr 4:113,451,032...113,762,177
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G GSN gelsolin involved_in ISS
IEA
(PMID:30568254) BHF-UCL
Ensembl
PMID:30568254 GO_REF:0000107 NCBI chr 9:121,201,483...121,332,844
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 3:179,148,114...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G SGCD sarcoglycan delta acts_upstream_of_or_within ISO (MGI:1343715|PMID:10481911) MGI PMID:10481911 MGI:1343715 NCBI chr 5:155,728,636...156,767,788
Ensembl chr 5:155,870,344...156,767,788
JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in IEA
ISO
Ensembl
RGD
PMID:20868366 GO_REF:0000107 RGD:7349316 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
G UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (MGI:5305502|PMID:22192413) MGI PMID:22192413 MGI:5305502 NCBI chr  Y:13,231,827...13,480,670
Ensembl chr  Y:13,234,577...13,480,673
JBrowse link
cytoplasmic actin-based contraction involved in cell motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIMCH1 LIM and calponin homology domains 1 involved_in IMP (PMID:28228547) CACAO PMID:28228547 NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044
JBrowse link
G SHTN1 shootin 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:116,881,477...117,126,586
Ensembl chr10:116,881,477...117,126,586
JBrowse link
G VIL1 villin 1 involved_in IDA (PMID:15342783) UniProt PMID:15342783 NCBI chr 2:218,419,123...218,453,295
Ensembl chr 2:218,419,121...218,453,295
JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr12:1,969,552...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr10:18,140,424...18,545,881
Ensembl chr10:18,140,424...18,543,557
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IMP (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 involved_in IEA
ISS
(PMID:19139040) Ensembl
BHF-UCL
PMID:19139040 GO_REF:0000107 NCBI chr 5:114,055,978...114,496,500
Ensembl chr 5:114,055,926...114,496,500
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251 PMID:25786344 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP (PMID:9354802) BHF-UCL PMID:9354802 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNE1B potassium voltage-gated channel subfamily E regulatory subunit 1B involved_in IEA GOC GO_REF:0000108 NCBI chr21:7,816,677...7,829,632
Ensembl chr21:7,816,675...7,829,926
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IMP (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GOC GO_REF:0000108 NCBI chr11:74,454,841...74,467,729
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,051,814...223,198,399
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IMP (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IEA GOC GO_REF:0000108 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in IMP (PMID:20558321) BHF-UCL PMID:20558321 NCBI chr12:21,764,955...21,775,593
Ensembl chr12:21,764,955...21,775,600
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IBA
IMP
(PMID:21873635)
(PMID:8528244)
GO_Central
BHF-UCL
PMID:8528244 PMID:21873635 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYH2 myosin heavy chain 2 involved_in NAS (PMID:3904738) BHF-UCL PMID:3904738 NCBI chr17:10,521,148...10,549,658
Ensembl chr17:10,521,148...10,549,700
JBrowse link
G MYH3 myosin heavy chain 3 involved_in TAS Reactome Reactome:R-HSA-390522 NCBI chr17:10,628,527...10,678,347
Ensembl chr17:10,628,526...10,657,309
JBrowse link
G MYH4 myosin heavy chain 4 involved_in NAS (PMID:3904738) BHF-UCL PMID:3904738 NCBI chr17:10,443,058...10,469,559
Ensembl chr17:10,443,290...10,469,559
JBrowse link
G MYH6 myosin heavy chain 6 involved_in TAS
IMP
(PMID:16088376) Reactome
HGNC-UCL
PMID:16088376 Reactome:R-HSA-390522 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
JBrowse link
G MYH7 myosin heavy chain 7 involved_in IMP (PMID:16088376), (PMID:8514894) HGNC-UCL PMID:8514894 PMID:16088376 NCBI chr14:23,412,740...23,435,677
Ensembl chr14:23,412,740...23,435,660
JBrowse link
G MYH8 myosin heavy chain 8 involved_in IMP
TAS
(PMID:17041932) BHF-UCL
Reactome
PMID:17041932 Reactome:R-HSA-390522 NCBI chr17:10,390,322...10,421,950
Ensembl chr17:10,390,322...10,421,950
JBrowse link
G MYL1 myosin light chain 1 involved_in NAS (PMID:3904738) BHF-UCL PMID:3904738 NCBI chr 2:210,290,150...210,315,174
Ensembl chr 2:210,290,150...210,315,174
JBrowse link
G MYL6 myosin light chain 6 involved_in TAS (PMID:2304459) HGNC-UCL PMID:2304459 NCBI chr12:56,158,359...56,161,579
Ensembl chr12:56,158,346...56,163,496
JBrowse link
G MYL6B myosin light chain 6B involved_in TAS (PMID:2304459) HGNC-UCL PMID:2304459 NCBI chr12:56,152,587...56,157,982
Ensembl chr12:56,152,256...56,159,647
JBrowse link
G TNNT2 troponin T2, cardiac type involved_in IDA (PMID:12186860), (PMID:15923195) UniProt PMID:12186860 PMID:15923195 NCBI chr 1:201,359,014...201,377,828
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
G TPM1 tropomyosin 1 involved_in ISS (PMID:11136687) BHF-UCL PMID:11136687 NCBI chr15:63,042,698...63,071,915
Ensembl chr15:63,042,632...63,071,915
JBrowse link
myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPDR1 ependymin related 1 involved_in IMP (PMID:27245865) UniProt PMID:27245865 NCBI chr 7:37,920,640...37,951,936
Ensembl chr 7:37,683,843...37,951,936
JBrowse link
negative regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS1 nitric oxide synthase 1 ISO RGD PMID:10727442 RGD:13824993 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IMP (PMID:22987075) BHF-UCL PMID:22987075 NCBI chr11:74,454,841...74,467,729
Ensembl chr11:74,454,841...74,467,729
JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBN1 drebrin 1 ISO RGD PMID:17543276 RGD:10398727 NCBI chr 5:177,456,610...177,480,368
Ensembl chr 5:177,456,608...177,474,401
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in ISS
ISO
BHF-UCL
RGD
PMID:23954346 GO_REF:0000024 RGD:10003031 NCBI chr19:49,157,792...49,211,841
Ensembl chr19:49,157,741...49,211,836
JBrowse link
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:19443576 RGD:7205486 NCBI chr16:1,153,106...1,221,769
Ensembl chr16:1,153,106...1,221,771
JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 involved_in ISO (MGI:6304509|PMID:30299255) UniProt PMID:30299255 MGI:6304509 NCBI chr 3:155,290,227...155,293,683
Ensembl chr 3:155,290,227...155,293,683
JBrowse link
positive regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle ISO RGD PMID:24204762 RGD:12879446 NCBI chr10:88,935,074...88,991,397
Ensembl chr10:88,935,074...88,991,339
JBrowse link
positive regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:19239477 RGD:10045899 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,808
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS1AP nitric oxide synthase 1 adaptor protein involved_in ISS (PMID:18337493) BHF-UCL PMID:18337493 NCBI chr 1:162,069,691...162,370,475
Ensembl chr 1:162,069,691...162,370,475
JBrowse link
G RNF207 ring finger protein 207 involved_in ISS
IMP
(PMID:25281747) BHF-UCL PMID:25281747 GO_REF:0000024 NCBI chr 1:6,206,004...6,221,299
Ensembl chr 1:6,205,475...6,221,299
JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:12571597) BHF-UCL PMID:12571597 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IMP (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr 1:147,756,199...147,781,127
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IMP (PMID:17875969) BHF-UCL PMID:17875969 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP9 A-kinase anchoring protein 9 involved_in IMP (PMID:18093912) BHF-UCL PMID:18093912 NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in IC (PMID:12676813) BHF-UCL PMID:12676813 NCBI chr 4:113,451,032...113,762,177
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CAV1 caveolin 1 involved_in IC (PMID:18923542) BHF-UCL PMID:18923542 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CAV3 caveolin 3 involved_in IMP (PMID:17060380) BHF-UCL PMID:17060380 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G FGF13 fibroblast growth factor 13 involved_in ISS (PMID:21817159) BHF-UCL PMID:21817159 NCBI chr  X:138,614,727...139,222,889
Ensembl chr  X:138,614,727...139,222,777
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IMP (PMID:16407510) BHF-UCL PMID:16407510 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in IMP (PMID:21621375) BHF-UCL PMID:21621375 NCBI chr17:8,288,670...8,290,087
Ensembl chr17:8,288,654...8,290,092
JBrowse link
regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor involved_in IEA
ISO
Ensembl
RGD
PMID:19525381 GO_REF:0000107 RGD:2317914 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19525381 PMID:22216755 RGD:2317914 RGD:6893639 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G AKAP6 A-kinase anchoring protein 6 involved_in ISO PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chr14:32,203,610...32,837,684
Ensembl chr14:32,329,298...32,837,684
JBrowse link
G ANK2 ankyrin 2 involved_in IGI (PMID:17242276) BHF-UCL PMID:17242276 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in IEA
ISO
Ensembl
RGD
PMID:15629895 GO_REF:0000107 RGD:6903236 NCBI chr 1:116,372,986...116,410,259
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 involved_in IEA
ISO
Ensembl
RGD
PMID:17442282 GO_REF:0000107 RGD:6903343 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G CASQ2 calsequestrin 2 involved_in ISO PMID:17569730 BHF-UCL PMID:17569730 RGD:2314601 NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,700,021...115,768,714
JBrowse link
G FXYD1 FXYD domain containing ion transport regulator 1 ISO RGD PMID:14684371 RGD:9685468 NCBI chr19:35,137,206...35,143,109
Ensembl chr19:35,138,824...35,143,109
JBrowse link
G GATA4 GATA binding protein 4 involved_in IEA
ISO
Ensembl
RGD
PMID:21702924 GO_REF:0000107 RGD:7207043 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA
ISO
Ensembl
RGD
PMID:22426100 GO_REF:0000107 RGD:7247430 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G PDE4B phosphodiesterase 4B involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579
JBrowse link
G PDE4D phosphodiesterase 4D involved_in IBA
ISO
ISS
(PMID:21873635)
(PMID:21903937)
GO_Central
RGD
BHF-UCL
PMID:19801680 PMID:21873635 PMID:21903937 GO_REF:0000024 RGD:7327160 NCBI chr 5:58,969,038...60,524,329
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
G PLN phospholamban involved_in
acts_upstream_of_or_within
IC
ISO
(PMID:19708671)
(MGI:3655311|PMID:8620604)
BHF-UCL
MGI
PMID:8620604 PMID:19708671 MGI:3655311 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:22529811)
(MGI:3695100|PMID:16172272)
BHF-UCL
MGI
PMID:16172272 PMID:22529811 MGI:3695100 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G SRI sorcin involved_in IMP (PMID:12754254), (PMID:17130302) BHF-UCL PMID:12754254 PMID:17130302 NCBI chr 7:88,205,115...88,226,976
Ensembl chr 7:88,205,115...88,226,993
JBrowse link
G STC1 stanniocalcin 1 involved_in IDA (PMID:12663264) UniProt PMID:12663264 NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806
JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (MGI:5292424|PMID:21900893) BHF-UCL PMID:21900893 MGI:5292424 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599
JBrowse link
regulation of membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A involved_in IC BHF-UCL GO_REF:0000111 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYBPC3 myosin binding protein C3 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
JBrowse link
G MYLK2 myosin light chain kinase 2 involved_in IDA (PMID:16448786) BHF-UCL PMID:16448786 NCBI chr20:31,819,356...31,834,684
Ensembl chr20:31,819,308...31,834,689
JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNNC1 troponin C1, slow skeletal and cardiac type involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 3:52,451,100...52,454,041
Ensembl chr 3:52,451,100...52,454,041
JBrowse link
G TNNT2 troponin T2, cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,359,014...201,377,828
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDPN podoplanin involved_in IBA
ISS
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957
JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:15454078), (PMID:26253506) BHF-UCL PMID:15454078 PMID:26253506 NCBI chr12:1,969,552...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CAV1 caveolin 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CTNNA3 catenin alpha 3 involved_in IMP (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr10:65,912,523...67,696,217
Ensembl chr10:65,912,457...67,763,637
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in ISS (PMID:25447080) BHF-UCL PMID:25447080 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330
JBrowse link
G DSC2 desmocollin 2 involved_in IMP (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,840...31,102,522
JBrowse link
G DSG2 desmoglein 2 involved_in IMP (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173 PMID:23381804 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,498,177...31,549,008
JBrowse link
G DSP desmoplakin involved_in IMP (PMID:12373648) BHF-UCL PMID:12373648 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,617...7,586,714
JBrowse link
G JUP junction plakoglobin involved_in IMP (PMID:17924338) BHF-UCL PMID:17924338 NCBI chr17:41,754,608...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G PKP2 plakophilin 2 involved_in IMP (PMID:22889254) BHF-UCL PMID:22889254 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,755...32,896,777
JBrowse link
G RYR2 ryanodine receptor 2 involved_in IMP (PMID:17875969) BHF-UCL PMID:17875969 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:49,157,792...49,211,841
Ensembl chr19:49,157,741...49,211,836
JBrowse link
ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IMP (PMID:17242276) BHF-UCL PMID:17242276 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G CAV3 caveolin 3 involved_in ISS (PMID:22879586) BHF-UCL PMID:22879586 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:1197846|PMID:9501070) MGI PMID:9501070 MGI:1197846 NCBI chr 1:147,756,199...147,781,127
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like involved_in IMP (PMID:17967977), (PMID:19666841) BHF-UCL PMID:17967977 PMID:19666841 NCBI chr 3:32,106,620...32,168,715
Ensembl chr 3:32,105,689...32,168,709
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IMP
IBA
(PMID:9354802)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:9354802 PMID:21873635 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNE1B potassium voltage-gated channel subfamily E regulatory subunit 1B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:7,816,677...7,829,632
Ensembl chr21:7,816,675...7,829,926
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IMP
(PMID:21873635)
(MGI:3813163|PMID:18603586)
(PMID:10219239)
GO_Central
MGI
BHF-UCL
PMID:10219239 PMID:18603586 PMID:21873635 MGI:3813163 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:74,454,841...74,467,729
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,051,814...223,198,399
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IMP
IBA
(PMID:21493962)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:21493962 PMID:21873635 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IMP (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase involved_in ISS (PMID:22879586) BHF-UCL PMID:22879586 NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
JBrowse link
G PKP2 plakophilin 2 involved_in IMP (PMID:22889254) BHF-UCL PMID:22889254 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,755...32,896,777
JBrowse link
G RYR2 ryanodine receptor 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within
IMP
ISO
IBA
(PMID:20042427)
(MGI:5294649|PMID:19351516)
(PMID:21873635)
BHF-UCL
MGI
GO_Central
PMID:19351516 PMID:20042427 PMID:21873635 MGI:5294649 NCBI chr11:123,629,187...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IMP (PMID:22529811) BHF-UCL PMID:22529811 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G SNTA1 syntrophin alpha 1 involved_in IMP (PMID:18591664) BHF-UCL PMID:18591664 NCBI chr20:33,407,957...33,443,853
Ensembl chr20:33,407,957...33,443,763
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    cellular process 17456
      actin filament-based process 865
        actin filament-based movement 139
          actin-mediated cell contraction 109
            actin-myosin filament sliding + 16
            apical constriction + 5
            cardiac muscle cell contraction + 78
            cytoplasmic actin-based contraction involved in cell motility + 3
            hepatic stellate cell contraction + 2
            myofibroblast contraction + 3
paths to the root