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ONTOLOGY REPORT - ANNOTATIONS


Term:actin-mediated cell contraction
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Accession:GO:0070252 term browser browse the term
Definition:The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.


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actin-mediated cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EMP2 epithelial membrane protein 2 involved_in ISO (PMID:18469192), (PMID:22728127) UniProt PMID:18469192 PMID:22728127 NCBI chr16:9,465,589...9,517,593
Ensembl chr16:10,694,425...10,744,744
JBrowse link
G LOC100987752 actin alpha cardiac muscle 1 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) MGI PMID:22750946 MGI:5468414 NCBI chr15:13,707,475...13,712,905
Ensembl chr15:31,966,278...31,971,782
JBrowse link
G MYH2 myosin heavy chain 2 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) MGI PMID:22750946 MGI:5468414 NCBI chr17:41,103,730...41,132,264
Ensembl chr17:45,851,160...45,879,666
JBrowse link
G PARVA parvin alpha involved_in ISO (MGI:4368016|PMID:19798050) UniProt PMID:19798050 MGI:4368016 NCBI chr11:12,544,232...12,701,517
Ensembl chr11:12,237,446...12,387,584
JBrowse link
G PDPN podoplanin involved_in ISO (MGI:5614157|PMID:25341788) UniProt PMID:25341788 MGI:5614157 NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584
JBrowse link
actin-myosin filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100987752 actin alpha cardiac muscle 1 involved_in ISO (PMID:19799913) BHF-UCL PMID:19799913 NCBI chr15:13,707,475...13,712,905
Ensembl chr15:31,966,278...31,971,782
JBrowse link
apical constriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC88C coiled-coil domain containing 88C involved_in ISO (PMID:30948426) UniProt PMID:30948426 NCBI chr14:71,897,602...72,044,242
Ensembl chr14:91,244,434...91,393,715
JBrowse link
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 acts_upstream_of_or_within ISO (MGI:4438998|PMID:20103536) MGI PMID:20103536 MGI:4438998 NCBI chr2B:6,945,289...7,111,595
Ensembl chr2B:120,521,145...120,687,209
JBrowse link
G FRMD6 FERM domain containing 6 acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chr14:32,093,017...32,334,665
Ensembl chr14:50,540,193...50,620,955
JBrowse link
G PARD3 par-3 family cell polarity regulator acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chr10:34,225,791...34,933,907
Ensembl chr10:34,808,380...35,393,287
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 acts_upstream_of_or_within ISO (MGI:5086051|PMID:21685893) MGI PMID:21685893 MGI:5086051 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086
JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISO (PMID:17242276), (PMID:18832177), (PMID:21859974)
(MGI:5427070|PMID:21859974)
BHF-UCL PMID:17242276 PMID:18832177 PMID:21859974 MGI:5427070 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,165,057...5,168,307 JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:18313602) BHF-UCL PMID:18313602 NCBI chr  X:98,731,109...98,732,575
Ensembl chr  X:109,202,320...109,202,748
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251) BHF-UCL PMID:12522251 NCBI chr11:2,469,750...2,874,467 JBrowse link
G NUP155 nucleoporin 155 acts_upstream_of_or_within ISO (MGI:3839697|PMID:19070573) MGI PMID:19070573 MGI:3839697 NCBI chr 5:73,000,597...73,080,417
Ensembl chr 5:78,285,001...78,360,601
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in ISO (PMID:21051419) BHF-UCL PMID:21051419 NCBI chr11:118,460,860...118,486,563
Ensembl chr11:122,377,643...122,403,063
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:15454078) BHF-UCL PMID:15454078 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in ISO (PMID:21131953) BHF-UCL PMID:21131953 NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO (PMID:25527503) BHF-UCL PMID:25527503 NCBI chr 7:73,917,439...74,410,627
Ensembl chr 7:87,579,004...88,068,482
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:6402838 NCBI chr 1:114,433,203...114,651,894
Ensembl chr 1:125,696,907...125,909,814
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:10400998) BHF-UCL PMID:10400998 NCBI chr21:20,818,395...20,884,053 JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in ISO (PMID:11371347) BHF-UCL PMID:11371347 NCBI chr17:64,097,908...64,112,914
Ensembl chr17:69,487,846...69,489,129
JBrowse link
G LOC100983419 voltage-dependent T-type calcium channel subunit alpha-1G involved_in ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166
Ensembl chr17:49,529,402...49,595,166
JBrowse link
G PKP2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chr12:53,322,227...53,428,747
Ensembl chr12:55,925,174...56,030,998
JBrowse link
G SCN1A sodium voltage-gated channel alpha subunit 1 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr2B:53,258,614...53,348,131
Ensembl chr2B:170,736,651...170,822,014
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in ISO (PMID:19808477) BHF-UCL PMID:19808477 NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in ISO (PMID:19808477) BHF-UCL PMID:19808477 NCBI chr11:112,996,609...113,010,412
Ensembl chr11:116,928,676...116,942,500
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in ISO (PMID:21051419) BHF-UCL PMID:21051419 NCBI chr11:118,460,860...118,486,563
Ensembl chr11:122,377,643...122,403,063
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in ISO (PMID:17592081) BHF-UCL PMID:17592081 NCBI chr11:112,967,190...112,986,727
Ensembl chr11:116,899,268...116,918,892
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
ISO (PMID:21895525)
(MGI:6402838|PMID:32109384)
BHF-UCL
MGI
PMID:21895525 PMID:32109384 MGI:6402838 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in ISO PMID:12676814 BHF-UCL PMID:12676814 RGD:8656014 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387
JBrowse link
G GSN gelsolin involved_in ISO (MGI:6450443|PMID:30568254) BHF-UCL PMID:30568254 MGI:6450443 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (MGI:6450443|PMID:30568254) BHF-UCL PMID:30568254 MGI:6450443 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G SGCD sarcoglycan delta acts_upstream_of_or_within ISO (MGI:1343715|PMID:10481911) MGI PMID:10481911 MGI:1343715 NCBI chr 5:151,131,909...152,164,077
Ensembl chr 5:157,719,540...158,139,633
JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO RGD PMID:20868366 RGD:7349316 NCBI chr 1:26,359,818...26,418,910
Ensembl chr 1:27,414,937...27,475,089
JBrowse link
cytoplasmic actin-based contraction involved in cell motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIMCH1 LIM and calponin homology domains 1 involved_in ISO (PMID:28228547) CACAO PMID:28228547 NCBI chr 4:35,685,904...36,025,582
Ensembl chr 4:41,533,560...41,873,694
JBrowse link
G SHTN1 shootin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr10:113,466,218...113,587,490
Ensembl chr10:116,896,155...117,016,223
JBrowse link
G VIL1 villin 1 involved_in ISO (PMID:15342783) UniProt PMID:15342783 NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550
JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISO (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr10:18,459,528...18,862,495
Ensembl chr10:18,795,832...19,195,226
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:18065446) BHF-UCL PMID:18065446 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,165,057...5,168,307 JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in ISO (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:123,705,361...123,735,370
Ensembl chr11:127,606,208...127,634,213
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:5292192 NCBI chr 5:109,722,916...109,862,747
Ensembl chr 5:115,522,443...115,661,079
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251 PMID:25786344 NCBI chr11:2,469,750...2,874,467 JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) BHF-UCL PMID:9354802 NCBI chr21:20,818,395...20,884,053 JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:142,528,979...142,562,074 JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in ISO (PMID:20558321) BHF-UCL PMID:20558321 NCBI chr12:64,522,172...64,532,848
Ensembl chr12:67,127,263...67,137,128
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr11:2,469,750...2,874,467 JBrowse link
muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100978529 myosin-7 involved_in ISO (PMID:16088376), (PMID:8514894) HGNC-UCL PMID:8514894 PMID:16088376 NCBI chr14:4,231,344...4,254,295
Ensembl chr14:22,325,812...22,348,763
JBrowse link
G MYH6 myosin heavy chain 6 involved_in ISO (PMID:16088376) HGNC-UCL PMID:16088376 NCBI chr14:4,200,616...4,226,193
Ensembl chr14:22,294,965...22,321,331
JBrowse link
G MYH8 myosin heavy chain 8 involved_in ISO (PMID:17041932) BHF-UCL PMID:17041932 NCBI chr17:41,231,081...41,262,671
Ensembl chr17:45,978,472...46,010,038
JBrowse link
G TNNT2 troponin T2, cardiac type involved_in ISO (PMID:12186860), (PMID:15923195) UniProt PMID:12186860 PMID:15923195 NCBI chr 1:176,957,298...176,976,033 JBrowse link
G TPM1 tropomyosin 1 involved_in ISO PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chr15:41,989,239...42,018,520
Ensembl chr15:60,286,587...60,315,530
JBrowse link
myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPDR1 ependymin related 1 involved_in ISO (PMID:27245865) UniProt PMID:27245865 NCBI chr 7:38,556,734...38,588,059 JBrowse link
negative regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS1 nitric oxide synthase 1 ISO RGD PMID:10727442 RGD:13824993 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) BHF-UCL PMID:22987075 NCBI chr11:69,527,663...69,540,236
Ensembl chr11:72,835,048...72,835,359
JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBN1 drebrin 1 ISO RGD PMID:17543276 RGD:10398727 NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in ISO (MGI:5583915|PMID:24836577) ARUK-UCL PMID:24836577 MGI:5583915 NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378
JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23954346 RGD:10003031 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464
JBrowse link
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:19443576 RGD:7205486 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 involved_in ISO (MGI:6304509|PMID:30299255) UniProt PMID:30299255 MGI:6304509 NCBI chr 3:152,346,768...152,351,244
Ensembl chr 3:160,399,367...160,402,051
JBrowse link
positive regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle ISO RGD PMID:24204762 RGD:12879446 NCBI chr10:85,660,983...85,678,729
Ensembl chr10:89,164,344...89,182,080
JBrowse link
positive regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:19239477 RGD:10045899 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF207 ring finger protein 207 involved_in ISO (PMID:25281747) BHF-UCL PMID:25281747 NCBI chr 1:4,972,787...4,986,992
Ensembl chr 1:6,229,241...6,242,770
JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISO (PMID:12571597)
(MGI:2449848|PMID:12571597)
BHF-UCL PMID:12571597 MGI:2449848 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905
JBrowse link
G GJA5 gap junction protein alpha 5 involved_in ISO (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413
JBrowse link
G RYR2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509
JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP9 A-kinase anchoring protein 9 involved_in ISO (PMID:18093912) BHF-UCL PMID:18093912 NCBI chr 7:83,942,590...84,108,648
Ensembl chr 7:97,540,356...97,705,608
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in ISO PMID:9851937 BHF-UCL PMID:9851937 RGD:10047146 NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923
JBrowse link
G CAV3 caveolin 3 involved_in ISO (PMID:17060380) BHF-UCL PMID:17060380 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G FGF13 fibroblast growth factor 13 involved_in ISO (MGI:5437408|PMID:21817159) BHF-UCL PMID:21817159 MGI:5437408 NCBI chr  X:127,764,648...128,353,928
Ensembl chr  X:138,023,016...138,103,217
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in ISO (PMID:16407510) BHF-UCL PMID:16407510 NCBI chr15:52,231,906...52,285,220
Ensembl chr15:70,997,020...71,042,285
JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) BHF-UCL PMID:21621375 NCBI chr17:43,369,556...43,371,025
Ensembl chr17:48,101,744...48,103,394
JBrowse link
regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO RGD PMID:19525381 RGD:2317914 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760
JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19525381 PMID:22216755 RGD:2317914 RGD:6893639 NCBI chr10:110,642,491...110,646,595 JBrowse link
G AKAP6 A-kinase anchoring protein 6 involved_in ISO PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chr14:12,978,221...13,602,732
Ensembl chr14:31,395,026...31,792,166
JBrowse link
G ANK2 ankyrin 2 involved_in ISO (PMID:17242276)
(MGI:3771114|PMID:17242276)
BHF-UCL PMID:17242276 MGI:3771114 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:15629895 RGD:6903236 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO RGD PMID:17442282 RGD:6903343 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303
JBrowse link
G CASQ2 calsequestrin 2 involved_in ISO PMID:17569730 BHF-UCL PMID:17569730 RGD:2314601 NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311
JBrowse link
G FXYD1 FXYD domain containing ion transport regulator 1 ISO RGD PMID:14684371 RGD:9685468 NCBI chr19:32,080,180...32,089,141
Ensembl chr19:40,824,448...40,827,039
JBrowse link
G GATA4 GATA binding protein 4 ISO RGD PMID:21702924 RGD:7207043 NCBI chr 8:7,442,921...7,526,731 JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO RGD PMID:22426100 RGD:7247430 NCBI chr17:64,097,908...64,112,914
Ensembl chr17:69,487,846...69,489,129
JBrowse link
G PDE4B phosphodiesterase 4B involved_in ISO (MGI:5286798|PMID:21670503) BHF-UCL PMID:21670503 MGI:5286798 NCBI chr 1:65,038,120...65,620,764
Ensembl chr 1:67,045,911...67,506,291
JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (MGI:5286798|PMID:21670503), (MGI:5442270|PMID:21903937)
PMID:19801680
RGD
BHF-UCL
PMID:19801680 PMID:21670503 PMID:21903937 MGI:5286798 MGI:5442270 RGD:7327160 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111
JBrowse link
G PLN phospholamban acts_upstream_of_or_within ISO (MGI:3655311|PMID:8620604) MGI PMID:8620604 MGI:3655311 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
ISO (PMID:22529811)
(MGI:3695100|PMID:16172272)
BHF-UCL
MGI
PMID:16172272 PMID:22529811 MGI:3695100 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
G SRI sorcin involved_in ISO (PMID:12754254), (PMID:17130302) BHF-UCL PMID:12754254 PMID:17130302 NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029
JBrowse link
G STC1 stanniocalcin 1 involved_in ISO (PMID:12663264) UniProt PMID:12663264 NCBI chr 8:23,089,339...23,102,245
Ensembl chr 8:20,023,469...20,036,321
JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (MGI:5292424|PMID:21900893) BHF-UCL PMID:21900893 MGI:5292424 NCBI chr2B:89,461,773...89,493,879
Ensembl chr2B:207,613,654...207,645,590
JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYLK2 myosin light chain kinase 2 involved_in ISO (PMID:16448786) BHF-UCL PMID:16448786 NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508
JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNNC1 troponin C1, slow skeletal and cardiac type involved_in ISO (MGI:3793933|PMID:10747195) BHF-UCL PMID:10747195 MGI:3793933 NCBI chr 3:52,393,106...52,396,076
Ensembl chr 3:53,621,749...53,624,726
JBrowse link
G TNNT2 troponin T2, cardiac type involved_in ISO PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chr 1:176,957,298...176,976,033 JBrowse link
regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDPN podoplanin involved_in ISO (MGI:5644359|PMID:25347465) UniProt PMID:25347465 MGI:5644359 NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584
JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in ISO (PMID:15454078), (PMID:26253506) BHF-UCL PMID:15454078 PMID:26253506 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826
JBrowse link
G CAV1 caveolin 1 involved_in ISO (MGI:5607357|PMID:25017399) BHF-UCL PMID:25017399 MGI:5607357 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CTNNA3 catenin alpha 3 involved_in ISO (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr10:62,388,454...64,177,116
Ensembl chr10:64,712,576...66,442,238
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in ISO (MGI:5816439|PMID:25447080) BHF-UCL PMID:25447080 MGI:5816439 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987
JBrowse link
G DSC2 desmocollin 2 involved_in ISO (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:24,296,505...24,332,997
Ensembl chr18:27,894,603...27,930,843
JBrowse link
G DSG2 desmoglein 2 involved_in ISO (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173 PMID:23381804 NCBI chr18:24,716,181...24,766,837
Ensembl chr18:28,313,223...28,363,786
JBrowse link
G DSP desmoplakin involved_in ISO (PMID:12373648) BHF-UCL PMID:12373648 NCBI chr 6:7,381,046...7,426,408
Ensembl chr 6:7,664,211...7,709,391
JBrowse link
G JUP junction plakoglobin involved_in ISO (PMID:17924338) BHF-UCL PMID:17924338 NCBI chr17:15,527,115...15,559,251
Ensembl chr17:15,747,163...15,777,479
JBrowse link
G PKP2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chr12:53,322,227...53,428,747
Ensembl chr12:55,925,174...56,030,998
JBrowse link
G RYR2 ryanodine receptor 2 involved_in ISO (PMID:17875969) BHF-UCL PMID:17875969 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464
JBrowse link
ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in ISO (PMID:17242276) BHF-UCL PMID:17242276 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905
JBrowse link
G CAV3 caveolin 3 involved_in ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:1197846|PMID:9501070) MGI PMID:9501070 MGI:1197846 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413
JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:17967977), (PMID:19666841) BHF-UCL PMID:17967977 PMID:19666841 NCBI chr 3:32,026,586...32,088,512
Ensembl chr 3:32,342,776...32,404,172
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) BHF-UCL PMID:9354802 NCBI chr21:20,818,395...20,884,053 JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within
ISO (PMID:10219239)
(MGI:3813163|PMID:18603586)
BHF-UCL
MGI
PMID:10219239 PMID:18603586 MGI:3813163 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:21493962) BHF-UCL PMID:21493962 NCBI chr  X:98,731,109...98,732,575
Ensembl chr  X:109,202,320...109,202,748
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr 7:142,528,979...142,562,074 JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr11:2,469,750...2,874,467 JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase involved_in ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr18:51,428,077...51,792,995
Ensembl chr18:54,867,149...55,123,423
JBrowse link
G PKP2 plakophilin 2 involved_in ISO (PMID:22889254) BHF-UCL PMID:22889254 NCBI chr12:53,322,227...53,428,747
Ensembl chr12:55,925,174...56,030,998
JBrowse link
G RYR2 ryanodine receptor 2 involved_in ISO (MGI:3820489|PMID:17872467) BHF-UCL PMID:17872467 MGI:3820489 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20042427)
(MGI:5294649|PMID:19351516)
BHF-UCL
MGI
PMID:19351516 PMID:20042427 MGI:5294649 NCBI chr11:118,460,860...118,486,563
Ensembl chr11:122,377,643...122,403,063
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in ISO (PMID:22529811) BHF-UCL PMID:22529811 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
G SNTA1 syntrophin alpha 1 involved_in ISO (PMID:18591664) BHF-UCL PMID:18591664 NCBI chr20:29,696,137...29,732,258
Ensembl chr20:30,810,787...30,844,476
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12657
    cellular process 11790
      actin filament-based process 641
        actin filament-based movement 111
          actin-mediated cell contraction 93
            actin-myosin filament sliding + 9
            apical constriction + 5
            cardiac muscle cell contraction + 68
            cytoplasmic actin-based contraction involved in cell motility + 3
            hepatic stellate cell contraction + 2
            myofibroblast contraction + 3
paths to the root