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ONTOLOGY REPORT - ANNOTATIONS

Term:actin-mediated cell contraction
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Accession:GO:0070252 term browser browse the term
Definition:The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.


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actin-mediated cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin, alpha, cardiac muscle 1 acts_upstream_of_or_within ISO (PMID:22750946) RGD PMID:22750946 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18469192), (PMID:22728127)		 UniProt
RGD		 PMID:18469192 PMID:22728127 GO_REF:0000024 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733 		JBrowse link
G Myh2 myosin heavy chain 2 acts_upstream_of_or_within ISO (PMID:22750946) RGD PMID:22750946 NCBI chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236 		JBrowse link
G Parva parvin, alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19798050)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19798050 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:166,547,142...166,704,958
Ensembl chr 1:166,547,132...166,704,950 		JBrowse link
G Pdpn podoplanin involved_in ISS
ISO		 GO_REF:0000024
(PMID:25341788)		 UniProt
RGD		 PMID:25341788 GO_REF:0000024 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
actin-myosin filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin, alpha, cardiac muscle 1 involved_in ISO
IBA		 (PMID:19799913)
GO_REF:0000033		 RGD
GO_Central		 PMID:19799913 GO_REF:0000033 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
apical constriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc88c coiled-coil domain containing 88C involved_in ISO (PMID:30948426) RGD PMID:30948426 NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555 		JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 acts_upstream_of_or_within ISO (PMID:20103536) RGD PMID:20103536 NCBI chr13:30,670,792...30,770,213
Ensembl chr13:30,669,764...30,768,360 		JBrowse link
G Frmd6 FERM domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:107927|MGI:2135608 (PMID:21685893)		 Ensembl
RGD		 PMID:21685893 GO_REF:0000107 NCBI chr 6:89,345,983...89,419,579
Ensembl chr 6:89,346,035...89,419,579 		JBrowse link
G Luzp1 leucine zipper protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:33346378)		 UniProt
RGD		 PMID:33346378 GO_REF:0000024 NCBI chr 5:148,706,094...148,781,616
Ensembl chr 5:148,706,138...148,781,609 		JBrowse link
G Pard3 par-3 family cell polarity regulator acts_upstream_of_or_within ISO MGI:107927|MGI:2442579 (PMID:21685893) RGD PMID:21685893 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2135608|MGI:2442579 (PMID:21685893)		 Ensembl
RGD		 PMID:21685893 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276), (PMID:18832177), (PMID:21859974)
(PMID:21859974)		 RGD PMID:17242276 PMID:18832177 PMID:21859974 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) RGD PMID:19343045 PMID:23264583 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:18313602) RGD PMID:18313602 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251) RGD PMID:12522251 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Nup155 nucleoporin 155 acts_upstream_of_or_within ISO MGI:3840086 (PMID:19070573) RGD PMID:19070573 NCBI chr 2:57,201,310...57,252,918
Ensembl chr 2:57,201,272...57,254,148 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO (PMID:21051419) RGD PMID:21051419 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18065446)		 BHF-UCL
RGD		 PMID:18065446 GO_REF:0000024 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO
ISS		 (PMID:15454078)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:15454078 GO_REF:0000024 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in ISO
IEA		 (PMID:21131953)
GO_REF:0000107		 RGD
Ensembl		 PMID:21131953 GO_REF:0000107 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G involved_in ISS GO_REF:0000024 BHF-UCL GO_REF:0000024 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO
IEA		 (PMID:25527503)
GO_REF:0000107		 RGD
Ensembl		 PMID:25527503 GO_REF:0000107 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:10400998) RGD PMID:10400998 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 involved_in ISO (PMID:11371347) RGD PMID:11371347 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445 		JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730 		JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 involved_in ISO
IEA		 (PMID:27207958)
GO_REF:0000107		 RGD
Ensembl		 PMID:27207958 GO_REF:0000107 NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IBA
IEA		 (PMID:19808477)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:19808477 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in ISO
IBA		 (PMID:19808477)
GO_REF:0000033		 RGD
GO_Central		 PMID:19808477 GO_REF:0000033 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO (PMID:21051419) RGD PMID:21051419 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISO
IBA		 (PMID:17592081)
GO_REF:0000033		 RGD
GO_Central		 PMID:17592081 GO_REF:0000033 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
ISS		 (PMID:21895525)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:21895525 GO_REF:0000024 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 GO_REF:0000107
MGI:6389242 (PMID:31575858)		 Ensembl
RGD		 PMID:31575858 GO_REF:0000107 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in IDA PMID:12676814 BHF-UCL PMID:12676814 RGD:8656014 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Gsn gelsolin involved_in IEA
ISO		 GO_REF:0000107
(PMID:30568254)		 Ensembl
RGD		 PMID:30568254 GO_REF:0000107 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO (PMID:30568254) RGD PMID:30568254 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Sgcd sarcoglycan, delta acts_upstream_of_or_within ISO MGI:2154694 (PMID:10481911) RGD PMID:10481911 NCBI chr10:31,346,480...32,328,364
Ensembl chr10:31,280,511...31,724,840 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 IEP RGD PMID:20868366 RGD:7349316 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (PMID:22192413) RGD PMID:22192413 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422 		JBrowse link
cytoplasmic actin-based contraction involved in cell motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Limch1 LIM and calponin homology domains 1 involved_in ISO (PMID:28228547) RGD PMID:28228547 NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191 		JBrowse link
G Shtn1 shootin 1 involved_in IDA PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr 1:258,121,966...258,225,861
Ensembl chr 1:258,121,968...258,228,265 		JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15342783) RGD PMID:15342783 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858 		JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO
ISS		 (PMID:17224476)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:17224476 GO_REF:0000024 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17224476)		 BHF-UCL
Ensembl
RGD		 PMID:17224476 GO_REF:0000024 GO_REF:0000107 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA		 (PMID:18065446)
GO_REF:0000107		 RGD
Ensembl		 PMID:18065446 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) RGD PMID:19343045 PMID:23264583 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 involved_in ISO
IEA		 (PMID:20560207)
GO_REF:0000107		 RGD
Ensembl		 PMID:20560207 GO_REF:0000107 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (PMID:19139040) RGD PMID:19139040 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA		 (PMID:12522251), (PMID:25786344)
GO_REF:0000107		 RGD
Ensembl		 PMID:12522251 PMID:25786344 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25447080)		 Ensembl
RGD		 PMID:25447080 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) RGD PMID:9354802 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979 		JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 involved_in ISO (PMID:20558321) RGD PMID:20558321 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:8528244)
MGI:2680653 (PMID:12766260), (PMID:15004216)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:8528244 PMID:12766260 PMID:15004216 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102551071 myosin light polypeptide 6-like involved_in TAS PMID:2304459 HGNC-UCL PMID:2304459 RGD:8554813 NCBI chr13:9,903,286...9,903,991 JBrowse link
G Myh6 myosin heavy chain 6 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:16088376)		 Ensembl
GO_Central
RGD		 PMID:16088376 GO_REF:0000033 GO_REF:0000107 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myh7 myosin heavy chain 7 involved_in ISO
IBA
IEA		 (PMID:16088376), (PMID:8514894)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:8514894 PMID:16088376 GO_REF:0000033 GO_REF:0000107 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Myh8 myosin heavy chain 8 involved_in ISO
IEA		 (PMID:17041932)
GO_REF:0000107		 RGD
Ensembl		 PMID:17041932 GO_REF:0000107 NCBI chr10:51,963,510...51,993,103
Ensembl chr10:51,963,510...51,993,232 		JBrowse link
G Myl6 myosin light chain 6 involved_in TAS PMID:2304459 HGNC-UCL PMID:2304459 RGD:8554813 NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791 		JBrowse link
G Myl6l2 myosin light chain 6 like 2 involved_in TAS PMID:2304459 HGNC-UCL PMID:2304459 RGD:8554813 NCBI chr12:29,488,091...29,488,746
Ensembl chr12:29,488,256...29,488,711 		JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in ISO
IEA
ISS		 (PMID:12186860), (PMID:15923195)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12186860 PMID:15923195 GO_REF:0000024 GO_REF:0000107 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tpm1 tropomyosin 1 involved_in IDA PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epdr1 ependymin related 1 involved_in ISO (PMID:27245865) RGD PMID:27245865 NCBI chr17:45,333,932...45,358,597
Ensembl chr17:45,333,956...45,358,594 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in IEA
ISO		 GO_REF:0000107
(PMID:33397958), (PMID:36627242)		 Ensembl
RGD		 PMID:33397958 PMID:36627242 GO_REF:0000107 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
negative regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31754830 RGD:329403060 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
negative regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos1 nitric oxide synthase 1 IDA RGD PMID:10727442 RGD:13824993 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) RGD PMID:22987075 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 IDA RGD PMID:17543276 RGD:10398727 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24836577)		 Ensembl
RGD		 PMID:24836577 GO_REF:0000107 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23954346 RGD:10003031 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IMP RGD PMID:19443576 RGD:7205486 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Strit1 small transmembrane regulator of ion transport 1 involved_in ISO (PMID:30299255) RGD PMID:30299255 NCBI chr 2:147,935,219...147,938,083
Ensembl chr 2:147,935,222...147,938,083 		JBrowse link
positive regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle IMP RGD PMID:24204762 RGD:12879446 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 acts_upstream_of ISO (PMID:25281747) RGD PMID:25281747 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375 		JBrowse link
positive regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:19239477 RGD:10045899 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 IDA RGD PMID:30336567 RGD:155882532 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:12571597) RGD PMID:12571597 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:23348765) RGD PMID:23348765 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO
IEA		 (PMID:17875969)
GO_REF:0000107		 RGD
Ensembl		 PMID:17875969 GO_REF:0000107 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in ISO (PMID:18093912) RGD PMID:18093912 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in IDA PMID:9851937 BHF-UCL PMID:9851937 RGD:10047146 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in IC PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:17060380) RGD PMID:17060380 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISO (PMID:21817159) RGD PMID:21817159 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 involved_in ISO
IEA		 (PMID:16407510)
GO_REF:0000107		 RGD
Ensembl		 PMID:16407510 GO_REF:0000107 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639 		JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) RGD PMID:21621375 NCBI chr10:53,677,467...53,678,880
Ensembl chr10:53,677,467...53,678,840 		JBrowse link
regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA RGD PMID:19525381 RGD:2317914 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
IDA		 RGD PMID:22216755 PMID:19525381 RGD:6893639, RGD:2317914 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Ank2 ankyrin 2 involved_in ISO UniProtKB:Q8C8R3 (PMID:17242276) RGD PMID:17242276 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 IMP RGD PMID:15629895 RGD:6903236 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 IMP RGD PMID:17442282 RGD:6903343 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Casq2 calsequestrin 2 involved_in IMP PMID:17569730 BHF-UCL PMID:17569730 RGD:2314601 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267 		JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 IMP RGD PMID:14684371 RGD:9685468 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278 		JBrowse link
G Gata4 GATA binding protein 4 IMP RGD PMID:21702924 RGD:7207043 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 IMP RGD PMID:22426100 RGD:7247430 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445 		JBrowse link
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in IMP
ISO		 (PMID:21670503), (PMID:21903937)
PMID:19801680		 RGD PMID:21670503 PMID:21903937 PMID:19801680 PMID:19801680 RGD:7327160, RGD:7327160 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO MGI:2158357 (PMID:8620604) RGD PMID:8620604 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within		 ISO
ISS
IEA		 (PMID:22529811)
MGI:2179753 (PMID:16172272)
GO_REF:0000024
GO_REF:0000107		 RGD
BHF-UCL
Ensembl		 PMID:16172272 PMID:22529811 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Sri sorcin involved_in ISO (PMID:12754254), (PMID:17130302) RGD PMID:12754254 PMID:17130302 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO (PMID:12663264) RGD PMID:12663264 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO (PMID:21900893) RGD PMID:21900893 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylk2 myosin light chain kinase 2 involved_in ISO
IEA		 (PMID:16448786)
GO_REF:0000107		 RGD
Ensembl		 PMID:16448786 GO_REF:0000107 NCBI chr 3:141,376,450...141,388,357
Ensembl chr 3:141,376,691...141,387,728 		JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnc1 troponin C1, slow skeletal and cardiac type involved_in ISO (PMID:10747195) RGD PMID:10747195 NCBI chr16:6,400,801...6,405,634
Ensembl chr16:6,402,171...6,405,634 		JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in IMP PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdpn podoplanin involved_in ISS
ISO		 GO_REF:0000024
(PMID:25347465)		 UniProt
RGD		 PMID:25347465 GO_REF:0000024 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISS
ISO		 GO_REF:0000024
(PMID:15454078), (PMID:26253506)		 BHF-UCL
RGD		 PMID:15454078 PMID:26253506 GO_REF:0000024 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25017399)		 Ensembl
RGD		 PMID:25017399 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ctnna3 catenin alpha 3 involved_in ISO (PMID:23136403) RGD PMID:23136403 NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25447080)		 Ensembl
RGD		 PMID:25447080 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dsc2 desmocollin 2 involved_in ISO (PMID:23863954) RGD PMID:23863954 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392 		JBrowse link
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173), (PMID:23381804) RGD PMID:16505173 PMID:23381804 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156 		JBrowse link
G Dsp desmoplakin involved_in ISO (PMID:12373648) RGD PMID:12373648 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800 		JBrowse link
G Jup junction plakoglobin involved_in ISO
IEA		 (PMID:17924338)
GO_REF:0000107		 RGD
Ensembl		 PMID:17924338 GO_REF:0000107 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057 		JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO
IEA		 (PMID:17875969)
GO_REF:0000107		 RGD
Ensembl		 PMID:17875969 GO_REF:0000107 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA		 (PMID:27207958)
GO_REF:0000107		 RGD
Ensembl		 PMID:27207958 GO_REF:0000107 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
substrate-dependent cell migration, cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 NAS RGD PMID:11967023 RGD:728123 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276) RGD PMID:17242276 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Cav3 caveolin 3 involved_in IMP PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445238 (PMID:9501070) RGD PMID:9501070 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:17967977), (PMID:19666841) RGD PMID:17967977 PMID:19666841 NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO
IBA		 (PMID:9354802)
GO_REF:0000033		 RGD
GO_Central		 PMID:9354802 GO_REF:0000033 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10219239)
MGI:3699589 (PMID:18603586)
GO_REF:0000033		 RGD
GO_Central		 PMID:10219239 PMID:18603586 GO_REF:0000033 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979 		JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO
IBA		 (PMID:21493962)
GO_REF:0000033		 RGD
GO_Central		 PMID:21493962 GO_REF:0000033 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) RGD PMID:8528244 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in IMP PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17872467)		 Ensembl
RGD		 PMID:17872467 GO_REF:0000107 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20042427)
MGI:5294639 (PMID:19351516)
GO_REF:0000033		 RGD
GO_Central		 PMID:19351516 PMID:20042427 GO_REF:0000033 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA		 (PMID:22529811)
GO_REF:0000107		 RGD
Ensembl		 PMID:22529811 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Snta1 syntrophin, alpha 1 involved_in ISO (PMID:18591664) RGD PMID:18591664 NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      actin filament-based process 856
        actin filament-based movement 129
          actin-mediated cell contraction 105
            actin-myosin filament sliding + 12
            apical constriction + 6
            cardiac muscle cell contraction + 74
            cochlear outer hair cell electromotile response 0
            cytoplasmic actin-based contraction involved in cell motility + 4
            hepatic stellate cell contraction + 2
            myofibroblast contraction + 5
paths to the root