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ONTOLOGY REPORT - ANNOTATIONS


Term:actin-mediated cell contraction
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Accession:GO:0070252 term browser browse the term
Definition:The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.


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actin-mediated cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin, alpha, cardiac muscle 1 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) RGD PMID:22750946 MGI:5468414 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:18469192), (PMID:22728127)
UniProt
RGD
PMID:18469192 PMID:22728127 GO_REF:0000024 NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839
JBrowse link
G Myh2 myosin heavy chain 2 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) RGD PMID:22750946 MGI:5468414 NCBI chr10:53,711,895...53,738,164
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Parva parvin, alpha involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4368016|PMID:19798050)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19798050 GO_REF:0000024 GO_REF:0000107 MGI:4368016 NCBI chr 1:177,249,302...177,408,160
Ensembl chr 1:177,249,226...177,408,205
JBrowse link
G Pdpn podoplanin involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5614157|PMID:25341788)
GO_REF:0000024
RGD
UniProt
PMID:25341788, PMID:21873635 GO_REF:0000024 MGI:5614157, RGD:13792537 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
actin-myosin filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin, alpha, cardiac muscle 1 involved_in IBA
ISO
PMID:21873635
(PMID:19799913)
RGD PMID:19799913, PMID:21873635 RGD:13792537 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
apical constriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc88c coiled-coil domain containing 88C involved_in ISO (PMID:30948426) RGD PMID:30948426 NCBI chr 6:124,905,811...125,028,011
Ensembl chr 6:124,905,808...125,027,553
JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 acts_upstream_of_or_within ISO (MGI:4438998|PMID:20103536) RGD PMID:20103536 MGI:4438998 NCBI chr13:35,622,472...35,673,449
Ensembl chr13:35,580,098...35,668,968
JBrowse link
G Frmd6 FERM domain containing 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:107927|MGI:2135608 (MGI:5086051|PMID:21685893)
Ensembl
RGD
PMID:21685893 GO_REF:0000107 MGI:5086051 NCBI chr 6:93,281,382...93,358,888
Ensembl chr 6:93,281,408...93,358,840
JBrowse link
G Pard3 par-3 family cell polarity regulator acts_upstream_of_or_within ISO MGI:107927|MGI:2442579 (MGI:5086051|PMID:21685893) RGD PMID:21685893 MGI:5086051 NCBI chr19:60,017,746...60,580,628
Ensembl chr19:60,017,746...60,580,651
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2135608|MGI:2442579 (MGI:5086051|PMID:21685893)
Ensembl
RGD
PMID:21685893 GO_REF:0000107 MGI:5086051 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276), (PMID:18832177), (PMID:21859974)
(MGI:5427070|PMID:21859974)
RGD PMID:17242276 PMID:18832177 PMID:21859974 MGI:5427070 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) RGD PMID:19343045 PMID:23264583 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO (PMID:18313602) RGD PMID:18313602 NCBI chr  X:113,583,844...113,584,459
Ensembl chr  X:113,583,844...113,584,459
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:12522251) RGD PMID:12522251 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Nup155 nucleoporin 155 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3840086 (MGI:3839697|PMID:19070573)
Ensembl
RGD
PMID:19070573 GO_REF:0000107 MGI:3839697 NCBI chr 2:57,206,665...57,258,242
Ensembl chr 2:57,206,613...57,258,295
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO (PMID:21051419) RGD PMID:21051419 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:18065446)
BHF-UCL
RGD
PMID:18065446 GO_REF:0000024 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO
ISS
(PMID:15454078)
GO_REF:0000024
RGD
BHF-UCL
PMID:15454078 GO_REF:0000024 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in ISO
IEA
(PMID:21131953)
GO_REF:0000107
RGD
Ensembl
PMID:21131953 GO_REF:0000107 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G involved_in ISS
ISO
GO_REF:0000024
(MGI:3714901|PMID:16690884)
BHF-UCL
RGD
PMID:16690884 GO_REF:0000024 MGI:3714901 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO
IEA
(PMID:25527503)
GO_REF:0000107
RGD
Ensembl
PMID:25527503 GO_REF:0000107 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 acts_upstream_of_or_within ISO (MGI:6402838|PMID:32109384) RGD PMID:32109384 MGI:6402838 NCBI chr 2:207,923,775...208,140,727
Ensembl chr 2:207,923,775...208,140,727
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:10400998) RGD PMID:10400998 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 involved_in ISO (PMID:11371347) RGD PMID:11371347 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 involved_in ISO (PMID:27207958) RGD PMID:27207958 NCBI chr 3:52,388,811...52,533,365
Ensembl chr 3:52,381,975...52,510,507
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IBA
(PMID:19808477)
PMID:21873635
RGD PMID:19808477, PMID:21873635 RGD:13792537 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in ISO
IBA
(PMID:19808477)
PMID:21873635
RGD PMID:19808477, PMID:21873635 RGD:13792537 NCBI chr 8:49,419,003...49,431,110
Ensembl chr 8:49,418,965...49,427,689
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IBA
ISO
PMID:21873635
(PMID:21051419)
RGD PMID:21051419, PMID:21873635 RGD:13792537 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISO
IBA
(PMID:17592081)
PMID:21873635
RGD PMID:17592081, PMID:21873635 RGD:13792537 NCBI chr 8:49,441,106...49,456,279
Ensembl chr 8:49,441,106...49,456,279
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:21895525)
(MGI:6402838|PMID:32109384)
GO_REF:0000024
RGD
BHF-UCL
PMID:21895525 PMID:32109384 GO_REF:0000024 MGI:6402838 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in IDA PMID:12676814 BHF-UCL PMID:12676814 RGD:8656014 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Gsn gelsolin involved_in ISO (MGI:6450443|PMID:30568254) RGD PMID:30568254 MGI:6450443 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO (MGI:6450443|PMID:30568254) RGD PMID:30568254 MGI:6450443 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Sgcd sarcoglycan, delta acts_upstream_of_or_within ISO MGI:2154694 (MGI:1343715|PMID:10481911) RGD PMID:10481911 MGI:1343715 NCBI chr10:32,062,946...32,471,454
Ensembl chr10:32,062,946...32,471,454
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IEP RGD PMID:20868366 RGD:7349316 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (MGI:5305502|PMID:22192413) RGD PMID:22192413 MGI:5305502 NCBI chr  Y:1,065,274...1,206,127
Ensembl chr  Y:989,240...1,206,096
JBrowse link
cytoplasmic actin-based contraction involved in cell motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Limch1 LIM and calponin homology domains 1 involved_in ISO (PMID:28228547) RGD PMID:28228547 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
JBrowse link
G Shtn1 shootin 1 involved_in IDA PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr 1:280,129,228...280,233,873
Ensembl chr 1:280,130,504...280,233,929
JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15342783) RGD PMID:15342783 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621
JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO
IEA
ISS
(PMID:17224476)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:17224476 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:17224476)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:17224476 GO_REF:0000024 GO_REF:0000107 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
(PMID:18065446)
GO_REF:0000107
RGD
Ensembl
PMID:18065446 GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:19343045), (PMID:23264583) RGD PMID:19343045 PMID:23264583 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 involved_in ISO (PMID:20560207) RGD PMID:20560207 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 involved_in ISO (MGI:5292192|PMID:19139040) RGD PMID:19139040 MGI:5292192 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:12522251), (PMID:25786344)
GO_REF:0000107
RGD
Ensembl
PMID:12522251 PMID:25786344 GO_REF:0000107 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:207,923,775...208,140,727
Ensembl chr 2:207,923,775...208,140,727
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) RGD PMID:9354802 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:84,688,873...84,693,066
Ensembl chr 9:84,689,150...84,690,338
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:113,583,844...113,584,459
Ensembl chr  X:113,583,844...113,584,459
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:21536673)
Ensembl
RGD
PMID:21536673 GO_REF:0000107 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 involved_in ISO (PMID:20558321) RGD PMID:20558321 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IBA
IEA
(PMID:8528244)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:8528244, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh6 myosin heavy chain 6 involved_in IEA
ISO
GO_REF:0000107
(PMID:16088376)
Ensembl
RGD
PMID:16088376 GO_REF:0000107 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 involved_in ISO
IEA
(PMID:16088376), (PMID:8514894)
GO_REF:0000107
RGD
Ensembl
PMID:8514894 PMID:16088376 GO_REF:0000107 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myh8 myosin heavy chain 8 involved_in IEA
ISO
GO_REF:0000107
(PMID:17041932)
Ensembl
RGD
PMID:17041932 GO_REF:0000107 NCBI chr10:53,818,818...53,848,490
Ensembl chr10:53,818,818...53,918,524
JBrowse link
G Myl6l myosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like involved_in TAS PMID:2304459 HGNC-UCL PMID:2304459 RGD:8554813
G Tnnt2 troponin T2, cardiac type involved_in ISO
ISS
(PMID:12186860), (PMID:15923195)
GO_REF:0000024
RGD
UniProt
PMID:12186860 PMID:15923195 GO_REF:0000024 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Tpm1 tropomyosin 1 involved_in IDA PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epdr1 ependymin related 1 involved_in ISO (PMID:27245865) RGD PMID:27245865 NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182
JBrowse link
negative regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos1 nitric oxide synthase 1 IDA RGD PMID:10727442 RGD:13824993 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO (PMID:22987075) RGD PMID:22987075 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 IDA RGD PMID:17543276 RGD:10398727 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5583915|PMID:24836577)
Ensembl
RGD
PMID:24836577 GO_REF:0000107 MGI:5583915 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23954346 RGD:10003031 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IMP RGD PMID:19443576 RGD:7205486 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
positive regulation of hepatic stellate cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle IMP RGD PMID:24204762 RGD:12879446 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
positive regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:19239477 RGD:10045899 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 involved_in ISO (PMID:25281747) RGD PMID:25281747 NCBI chr 5:169,486,253...169,500,451
Ensembl chr 5:169,486,257...169,499,268
JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:12571597)
(MGI:2449848|PMID:12571597)
RGD PMID:12571597 MGI:2449848 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:23348765) RGD PMID:23348765 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO
IEA
(PMID:17875969)
GO_REF:0000107
RGD
Ensembl
PMID:17875969 GO_REF:0000107 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in ISO (PMID:18093912) RGD PMID:18093912 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in IDA PMID:9851937 BHF-UCL PMID:9851937 RGD:10047146 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in IC PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:17060380) RGD PMID:17060380 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISO (MGI:5437408|PMID:21817159) RGD PMID:21817159 MGI:5437408 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 involved_in ISO
IEA
(PMID:16407510)
GO_REF:0000107
RGD
Ensembl
PMID:16407510 GO_REF:0000107 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) RGD PMID:21621375 NCBI chr10:55,559,049...55,560,420
Ensembl chr10:55,559,041...55,560,422
JBrowse link
regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA RGD PMID:19525381 RGD:2317914 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
IDA
RGD PMID:22216755, PMID:19525381 RGD:6893639, RGD:2317914 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Ank2 ankyrin 2 involved_in ISO UniProtKB:Q8C8R3 (PMID:17242276)
(MGI:3771114|PMID:17242276)
RGD PMID:17242276 MGI:3771114 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 IMP RGD PMID:15629895 RGD:6903236 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 IMP RGD PMID:17442282 RGD:6903343 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Casq2 calsequestrin 2 involved_in IMP PMID:17569730 BHF-UCL PMID:17569730 RGD:2314601 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 IMP RGD PMID:14684371 RGD:9685468 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Gata4 GATA binding protein 4 IMP RGD PMID:21702924 RGD:7207043 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 IMP RGD PMID:22426100 RGD:7247430 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA
ISO
GO_REF:0000107
(MGI:5286798|PMID:21670503)
Ensembl
RGD
PMID:21670503 GO_REF:0000107 MGI:5286798 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pde4d phosphodiesterase 4D involved_in IMP
ISO
IBA
(MGI:5286798|PMID:21670503), (MGI:5442270|PMID:21903937)
PMID:21873635
PMID:19801680
RGD PMID:21670503 PMID:21903937, PMID:19801680, PMID:21873635, PMID:19801680 MGI:5286798 MGI:5442270, RGD:7327160, RGD:13792537, RGD:7327160 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO MGI:2158357 (MGI:3655311|PMID:8620604) RGD PMID:8620604 MGI:3655311 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
MGI:2179753 (MGI:3695100|PMID:16172272)
(PMID:22529811)
BHF-UCL
Ensembl
RGD
PMID:16172272 PMID:22529811 GO_REF:0000024 GO_REF:0000107 MGI:3695100 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Sri sorcin involved_in ISO (PMID:12754254), (PMID:17130302) RGD PMID:12754254 PMID:17130302 NCBI chr 4:23,004,657...23,029,233
Ensembl chr 4:23,006,243...23,018,983
JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO (PMID:12663264) RGD PMID:12663264 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO (MGI:5292424|PMID:21900893) RGD PMID:21900893 MGI:5292424 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylk2 myosin light chain kinase 2 involved_in ISO
IEA
(PMID:16448786)
GO_REF:0000107
RGD
Ensembl
PMID:16448786 GO_REF:0000107 NCBI chr 3:148,386,185...148,397,851
Ensembl chr 3:148,386,189...148,399,501
JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnc1 troponin C1, slow skeletal and cardiac type involved_in ISO (MGI:3793933|PMID:10747195) RGD PMID:10747195 MGI:3793933 NCBI chr16:7,292,207...7,295,238
Ensembl chr16:7,292,096...7,295,465
JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in IMP PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
regulation of myofibroblast contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdpn podoplanin involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5644359|PMID:25347465)
PMID:21873635
UniProt
RGD
PMID:25347465, PMID:21873635 GO_REF:0000024 MGI:5644359, RGD:13792537 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034767.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr11:88,912,599...88,972,176 JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15454078), (PMID:26253506)
BHF-UCL
Ensembl
RGD
PMID:15454078 PMID:26253506 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5607357|PMID:25017399)
Ensembl
RGD
PMID:25017399 GO_REF:0000107 MGI:5607357 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ctnna3 catenin alpha 3 involved_in ISO (PMID:23136403) RGD PMID:23136403 NCBI chr20:25,063,124...26,640,428
Ensembl chr20:26,516,836...26,589,209
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5816439|PMID:25447080)
Ensembl
RGD
PMID:25447080 GO_REF:0000107 MGI:5816439 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link
G Dsc2 desmocollin 2 involved_in ISO (PMID:23863954) RGD PMID:23863954 NCBI chr18:11,826,705...11,858,801
Ensembl chr18:11,826,706...11,858,754
JBrowse link
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173), (PMID:23381804) RGD PMID:16505173 PMID:23381804 NCBI chr18:15,579,322...15,637,720
Ensembl chr18:15,579,315...15,637,715
JBrowse link
G Dsp desmoplakin involved_in ISO (PMID:12373648) RGD PMID:12373648 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Jup junction plakoglobin involved_in ISO (PMID:17924338) RGD PMID:17924338 NCBI chr10:88,280,517...88,307,451
Ensembl chr10:88,279,632...88,307,412
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO
IEA
(PMID:17875969)
GO_REF:0000107
RGD
Ensembl
PMID:17875969 GO_REF:0000107 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:27207958)
Ensembl
RGD
PMID:27207958 GO_REF:0000107 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
substrate-dependent cell migration, cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 NAS RGD PMID:11967023 RGD:728123 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034767.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr11:88,912,599...88,972,176 JBrowse link
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276) RGD PMID:17242276 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Cav3 caveolin 3 involved_in IMP PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445238 (MGI:1197846|PMID:9501070) RGD PMID:9501070 MGI:1197846 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like involved_in ISO (PMID:17967977), (PMID:19666841) RGD PMID:17967977 PMID:19666841 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO
IBA
(PMID:9354802)
PMID:21873635
RGD PMID:9354802, PMID:21873635 RGD:13792537 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:10219239)
MGI:3699589 (MGI:3813163|PMID:18603586)
PMID:21873635
RGD PMID:10219239 PMID:18603586, PMID:21873635 MGI:3813163, RGD:13792537 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:84,688,873...84,693,066
Ensembl chr 9:84,689,150...84,690,338
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO
IBA
(PMID:21493962)
PMID:21873635
RGD PMID:21493962, PMID:21873635 RGD:13792537 NCBI chr  X:113,583,844...113,584,459
Ensembl chr  X:113,583,844...113,584,459
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:8528244) RGD PMID:8528244 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in IMP PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:3820489|PMID:17872467)
Ensembl
RGD
PMID:17872467 GO_REF:0000107 MGI:3820489 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5294639 (MGI:5294649|PMID:19351516)
(PMID:20042427)
RGD PMID:19351516 PMID:20042427, PMID:21873635 MGI:5294649, RGD:13792537 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
(PMID:22529811)
GO_REF:0000107
RGD
Ensembl
PMID:22529811 GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Snta1 syntrophin, alpha 1 involved_in ISO (PMID:18591664) RGD PMID:18591664 NCBI chr 3:149,874,023...149,905,980
Ensembl chr 3:149,874,030...149,905,944
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      actin filament-based process 833
        actin filament-based movement 128
          actin-mediated cell contraction 98
            actin-myosin filament sliding + 10
            apical constriction + 5
            cardiac muscle cell contraction + 71
            cytoplasmic actin-based contraction involved in cell motility + 4
            hepatic stellate cell contraction + 2
            myofibroblast contraction + 3
paths to the root