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ONTOLOGY REPORT - ANNOTATIONS


Term:kynurenine metabolic process
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Accession:GO:0070189 term browser browse the term
Definition:The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
Synonyms:exact_synonym: kynurenine metabolism



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kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase involved_in IDA (PMID:18620547) UniProt PMID:18620547 NCBI chr 4:170,060,222...170,094,292
Ensembl chr 4:170,060,222...170,091,699
JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA
IBA
IDA
(PMID:10672018), (PMID:26752518), (PMID:29208702), (PMID:29429898) Ensembl
GO_Central
TreeGrafter
UniProt
PMID:10672018 PMID:26752518 PMID:29208702 PMID:29429898 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:241,532,378...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYAT1 kynurenine aminotransferase 1 involved_in IDA (PMID:19338303) UniProt PMID:19338303 NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,832,942...128,882,494
Ensembl chr 9:128,832,942...128,882,494
JBrowse link
G KYAT3 kynurenine aminotransferase 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:88,921,044...88,992,960
Ensembl chr 1:88,935,773...88,992,953
JBrowse link
L-kynurenine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH8A1 aldehyde dehydrogenase 8 family member A1 involved_in IEA UniProt GO_REF:0000041 NCBI chr 6:134,917,393...134,950,101
Ensembl chr 6:134,917,393...134,950,115
JBrowse link
G KYAT1 kynurenine aminotransferase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,832,942...128,882,494
Ensembl chr 9:128,832,942...128,882,494
JBrowse link
G KYAT3 kynurenine aminotransferase 3 involved_in IEA UniProt GO_REF:0000041 NCBI chr 1:88,921,044...88,992,960
Ensembl chr 1:88,935,773...88,992,953
JBrowse link
G KYNU kynureninase involved_in IEA UniProt GO_REF:0000041 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
L-kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase involved_in IEA GOC GO_REF:0000108 NCBI chr 4:170,060,222...170,094,292
Ensembl chr 4:170,060,222...170,091,699
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in IEA GOC GO_REF:0000108 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
JBrowse link
G KMO kynurenine 3-monooxygenase involved_in ISO
IEA
RGD
Ensembl
PMID:23690293 GO_REF:0000107 RGD:13513904 NCBI chr 1:241,532,378...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYAT1 kynurenine aminotransferase 1 ISO RGD PMID:7796908 RGD:9685040 NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,832,942...128,882,494
Ensembl chr 9:128,832,942...128,882,494
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(MGI:3587527|PMID:15866519) MGI
GO_Central
InterPro
UniProt
PMID:15866519 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 MGI:3587527 NCBI chr17:78,187,362...78,207,702
Ensembl chr17:78,187,358...78,207,702
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753) RGD
GO_Central
TreeGrafter
UniProt
Ensembl
InterPro
MGI
PMID:2419335 PMID:10719243 PMID:11513477 PMID:11751753 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 MGI:2151782 MGI:2156954 RGD:2290190 RGD:2290543 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
ISS
IDA
(MGI:3712725|PMID:17499941)
(PMID:17499941)
(PMID:17671174)
(MGI:3719924|PMID:17671174)
MGI
TreeGrafter
GO_Central
UniProt
Ensembl
InterPro
PMID:17499941 PMID:17671174 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 MGI:3712725 MGI:3719924 NCBI chr 8:39,934,651...40,016,392
Ensembl chr 8:39,934,614...40,016,392
JBrowse link
G KYNU kynureninase involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase involved_in IEA
IDA
(PMID:27762317) UniProt
InterPro
PMID:27762317 GO_REF:0000002 GO_REF:0000041 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19761
    metabolic process 12497
      cellular metabolic process 11163
        cellular ketone metabolic process 286
          kynurenine metabolic process 11
            L-kynurenine metabolic process + 7
            tryptophan catabolic process to kynurenine 5
Path 2
Term Annotations click to browse term
  biological_process 19761
    metabolic process 12497
      organic substance metabolic process 11988
        organic acid metabolic process 1057
          oxoacid metabolic process 1047
            carboxylic acid metabolic process 1020
              alpha-amino acid metabolic process 236
                kynurenine metabolic process 11
                  L-kynurenine metabolic process + 7
                  tryptophan catabolic process to kynurenine 5
paths to the root