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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of biomineral tissue development
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Accession:GO:0070169 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


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positive regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISO (PMID:25407797) RGD PMID:25407797 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181 		JBrowse link
G Atf4 activating transcription factor 4 acts_upstream_of_or_within ISO MGI:2180373|MGI:3819270|MGI:5550363|MGI:5812282 (MGI:5812283|PMID:27812542) RGD PMID:27812542 MGI:5812283 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta acts_upstream_of_or_within ISO (PMID:27812542) RGD PMID:27812542 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:29850565) RGD PMID:29850565 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISS
ISO		 GO_REF:0000024
(PMID:22901946)		 UniProt
RGD		 PMID:22901946 GO_REF:0000024 NCBI chr14:16,071,835...16,084,210
Ensembl chr14:16,073,058...16,080,129 		JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18436533)		 Ensembl
RGD		 PMID:18436533 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in IEA
ISO		 GO_REF:0000107
(PMID:18436533)		 Ensembl
RGD		 PMID:18436533 GO_REF:0000107 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in IEA
ISO		 GO_REF:0000107
(PMID:18436533)		 Ensembl
RGD		 PMID:18436533 GO_REF:0000107 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) RGD PMID:22419726 MGI:6211994 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688 		JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1859675 (MGI:3575849|PMID:15724149)		 Ensembl
RGD		 PMID:15724149 GO_REF:0000107 MGI:3575849 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6393219|PMID:24906289)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24906289 GO_REF:0000024 GO_REF:0000107 MGI:6393219 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)		 RGD PMID:25589784 MGI:5634871 NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5780494|PMID:26392310)		 UniProt
RGD		 PMID:26392310 GO_REF:0000024 MGI:5780494 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor involved_in ISO (PMID:21723284) RGD PMID:21723284 NCBI chr 6:25,315,236...25,319,804 JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009350|PMID:20675382)
(PMID:18436533), (PMID:20576608)		 UniProt
RGD		 PMID:18436533 PMID:20576608 PMID:20675382 GO_REF:0000024 MGI:5009350 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 IDA
ISO
ISS
IEA		 (PMID:14749725)
GO_REF:0000024
(PMID:14749725), (PMID:18436533)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:14749725 PMID:18436533 PMID:15352071 GO_REF:0000024 GO_REF:0000107, RGD:9068399 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20675382)		 Ensembl
RGD		 PMID:20675382 GO_REF:0000107 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Cd276 Cd276 molecule acts_upstream_of_or_within ISO MGI:3033707 (MGI:3052626|PMID:15317945) RGD PMID:15317945 MGI:3052626 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (MGI:3715055|PMID:17369251), (MGI:5427766|PMID:22615579) RGD PMID:17369251 PMID:22615579 MGI:3715055 MGI:5427766 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (MGI:4437389|PMID:20053668) RGD PMID:20053668 MGI:4437389 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4943600|PMID:21402791)		 UniProt
RGD		 PMID:21402791 GO_REF:0000024 MGI:4943600 NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398 		JBrowse link
G Gpm6b glycoprotein m6b involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21638316)		 UniProt
Ensembl
RGD		 PMID:21638316 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (MGI:4943600|PMID:21402791) RGD PMID:21402791 MGI:4943600 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Kl Klotho involved_in ISO
IEA		 (PMID:12110410)
GO_REF:0000107		 RGD
Ensembl		 PMID:12110410 GO_REF:0000107 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285459|PMID:21652706)		 UniProt
RGD		 PMID:21652706 GO_REF:0000024 MGI:5285459 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO MGI:5007248 (MGI:5008683|PMID:21606205) RGD PMID:21606205 MGI:5008683 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21723284)		 UniProt
Ensembl
RGD		 PMID:21723284 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO UniProtKB:Q91ZD1 (MGI:4950000|PMID:21262216) RGD PMID:21262216 MGI:4950000 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in ISO UniProtKB:Q9WVG7 (MGI:4950000|PMID:21262216) RGD PMID:21262216 MGI:4950000 NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (MGI:2667237|PMID:12677010), (MGI:3797675|PMID:18519738) RGD PMID:12677010 PMID:18519738 MGI:2667237 MGI:3797675 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) RGD PMID:19097194 MGI:3813934 NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556 		JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP RGD PMID:10807497 RGD:1642474 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pth parathyroid hormone involved_in IDA
ISO		 (PMID:17696759) RGD PMID:17696759 PMID:15758479 PMID:22445539 RGD:7207452, RGD:7242906 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Ptn pleiotrophin involved_in ISS
ISO		 GO_REF:0000024
(MGI:6294181|PMID:19442624)		 UniProt
RGD		 PMID:19442624 GO_REF:0000024 MGI:6294181 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) RGD PMID:25589784 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Smad3 SMAD family member 3 IDA rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO
IEA		 (MGI:6717031|PMID:33882302)
GO_REF:0000107		 RGD
Ensembl		 PMID:33882302 GO_REF:0000107 MGI:6717031 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO
ISS		 (PMID:19578371)
GO_REF:0000024		 RGD
UniProt		 PMID:19578371 GO_REF:0000024 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:17401695)
GO_REF:0000024		 RGD
AgBase		 PMID:17401695 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS		 (PMID:17401695)
GO_REF:0000024		 RGD
AgBase		 PMID:17401695 GO_REF:0000024 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO
IBA		 (PMID:20025746)
(MGI:4418582|PMID:20025746), (MGI:5700277|PMID:26207632)
PMID:21873635		 RGD PMID:20025746 PMID:26207632 PMID:21873635 MGI:4418582 MGI:5700277, RGD:13792537 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (MGI:3574150|PMID:15728361) RGD PMID:15728361 MGI:3574150 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:17720811)
GO_REF:0000107		 RGD
Ensembl		 PMID:17720811 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) RGD PMID:21784188 MGI:5291888 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO MGI:3840841 (MGI:5514358|PMID:21490954) RGD PMID:21490954 MGI:5514358 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477 		JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5613837|PMID:25407797)
PMID:21873635		 UniProt
RGD		 PMID:25407797 PMID:21873635 GO_REF:0000024 MGI:5613837, RGD:13792537 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO		 GO_REF:0000107
(MGI:6716964|PMID:26403673)		 Ensembl
RGD		 PMID:26403673 GO_REF:0000107 MGI:6716964 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO (MGI:3603472|PMID:16014627) RGD PMID:16014627 MGI:3603472 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Enam enamelin involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3796583 (MGI:5647983|PMID:24603688)		 RGD PMID:24603688 PMID:21873635 MGI:5647983, RGD:13792537 NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425 		JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISO
ISS
IBA		 (PMID:22901946)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:22901946 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr14:16,071,835...16,084,210
Ensembl chr14:16,073,058...16,080,129 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
positive regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfap2a transcription factor AP-2 alpha involved_in ISO
ISS		 (PMID:19578371)
GO_REF:0000024		 RGD
UniProt		 PMID:19578371 GO_REF:0000024 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Wnt6 Wnt family member 6 involved_in ISO (PMID:20113781) RGD PMID:20113781 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    positive regulation of biological process 6745
      positive regulation of biomineralization 57
        positive regulation of biomineral tissue development 56
          positive regulation of bone mineralization + 46
          positive regulation of shell calcification 0
          positive regulation of tooth mineralization + 8
Path 2
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure development 6376
        multicellular organism development 5800
          system development 5439
            animal organ development 4194
              biomineral tissue development 178
                regulation of biomineral tissue development 104
                  positive regulation of biomineral tissue development 56
                    positive regulation of bone mineralization + 46
                    positive regulation of shell calcification 0
                    positive regulation of tooth mineralization + 8
paths to the root