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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of biomineral tissue development
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Accession:GO:0070169 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.

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positive regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISO (PMID:25407797) RGD PMID:25407797 NCBI chr14:21,282,488...21,301,966
Ensembl chr14:21,286,510...21,299,068 		JBrowse link
G Atf4 activating transcription factor 4 acts_upstream_of_or_within ISO MGI:2180373|MGI:3819270|MGI:5550363|MGI:5812282 (MGI:5812283|PMID:27812542) RGD PMID:27812542 MGI:5812283 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in ISO (PMID:27812542) RGD PMID:27812542 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:29850565) RGD PMID:29850565 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586 		JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISO
ISS		 (PMID:22901946)
GO_REF:0000024		 RGD
UniProt		 PMID:22901946 GO_REF:0000024 NCBI chr14:17,575,295...17,583,214
Ensembl chr14:17,575,758...17,582,823 		JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA		 (PMID:18436533)
GO_REF:0000107		 RGD
Ensembl		 PMID:18436533 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in ISO
IEA		 (PMID:18436533)
GO_REF:0000107		 RGD
Ensembl		 PMID:18436533 GO_REF:0000107 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO
IEA		 (PMID:18436533)
GO_REF:0000107		 RGD
Ensembl		 PMID:18436533 GO_REF:0000107 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) RGD PMID:22419726 MGI:6211994 NCBI chr 2:8,926,843...9,504,455
Ensembl chr 2:8,926,850...9,504,134 		JBrowse link
G Adrb2 adrenoceptor beta 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1859675 (MGI:3575849|PMID:15724149)		 Ensembl
RGD		 PMID:15724149 GO_REF:0000107 MGI:3575849 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6393219|PMID:24906289)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24906289 GO_REF:0000024 GO_REF:0000107 MGI:6393219 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)		 RGD PMID:25589784 MGI:5634871 NCBI chr 7:137,142,063...137,335,208
Ensembl chr 7:137,142,170...137,335,208 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5780494|PMID:26392310)		 UniProt
RGD		 PMID:26392310 GO_REF:0000024 MGI:5780494 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579 		JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor involved_in ISO (PMID:21723284) RGD PMID:21723284 NCBI chr 6:26,680,628...26,685,185
Ensembl chr 6:26,680,598...26,685,235 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009350|PMID:20675382)
(PMID:18436533), (PMID:20576608)		 UniProt
RGD		 PMID:18436533 PMID:20576608 PMID:20675382 GO_REF:0000024 MGI:5009350 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IDA
ISS
ISO
IEA		 GO_REF:0000024
(PMID:14749725), (PMID:18436533)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:14749725 PMID:18436533, PMID:15352071 GO_REF:0000024 GO_REF:0000107, RGD:9068399 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20675382)		 Ensembl
RGD		 PMID:20675382 GO_REF:0000107 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312 		JBrowse link
G Cd276 Cd276 molecule acts_upstream_of_or_within ISO MGI:3033707 (MGI:3052626|PMID:15317945) RGD PMID:15317945 MGI:3052626 NCBI chr 8:63,312,060...63,350,411
Ensembl chr 8:63,318,019...63,350,269 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (MGI:3715055|PMID:17369251), (MGI:5427766|PMID:22615579) RGD PMID:17369251 PMID:22615579 MGI:3715055 MGI:5427766 NCBI chr12:17,913,771...17,972,733
Ensembl chr12:17,913,767...17,972,737 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (MGI:4437389|PMID:20053668) RGD PMID:20053668 MGI:4437389 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4943600|PMID:21402791)		 UniProt
RGD		 PMID:21402791 GO_REF:0000024 MGI:4943600 NCBI chr12:24,473,981...24,476,295
Ensembl chr12:24,473,981...24,476,295 		JBrowse link
G Gpm6b glycoprotein m6b involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:21638316)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21638316 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:29,604,607...29,751,174
Ensembl chr  X:29,607,075...29,648,403 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (MGI:4943600|PMID:21402791) RGD PMID:21402791 MGI:4943600 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248 		JBrowse link
G Kl Klotho involved_in IEA
ISO		 GO_REF:0000107
(PMID:12110410)		 Ensembl
RGD		 PMID:12110410 GO_REF:0000107 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285459|PMID:21652706)		 UniProt
RGD		 PMID:21652706 GO_REF:0000024 MGI:5285459 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO MGI:5007248 (MGI:5008683|PMID:21606205) RGD PMID:21606205 MGI:5008683 NCBI chr13:101,727,434...101,770,127
Ensembl chr13:101,727,935...101,761,541 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO
ISS		 (PMID:21723284)
GO_REF:0000024		 RGD
UniProt		 PMID:21723284 GO_REF:0000024 NCBI chr 1:105,348,577...106,218,970
Ensembl chr 1:105,349,069...106,218,958 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO UniProtKB:Q91ZD1 (MGI:4950000|PMID:21262216) RGD PMID:21262216 MGI:4950000 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in ISO UniProtKB:Q9WVG7 (MGI:4950000|PMID:21262216) RGD PMID:21262216 MGI:4950000 NCBI chr 7:74,047,820...74,055,096
Ensembl chr 7:74,047,814...74,055,256 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (MGI:2667237|PMID:12677010), (MGI:3797675|PMID:18519738) RGD PMID:12677010 PMID:18519738 MGI:2667237 MGI:3797675 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) RGD PMID:19097194 MGI:3813934 NCBI chr 6:6,427,657...6,436,974
Ensembl chr 6:6,427,657...6,436,974 		JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP RGD PMID:10807497 RGD:1642474 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693 		JBrowse link
G Pth parathyroid hormone involved_in IDA
ISO		 (PMID:17696759) RGD PMID:17696759, PMID:15758479, PMID:22445539 RGD:7207452, RGD:7242906 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761 		JBrowse link
G Ptn pleiotrophin involved_in ISS
ISO		 GO_REF:0000024
(MGI:6294181|PMID:19442624)		 UniProt
RGD		 PMID:19442624 GO_REF:0000024 MGI:6294181 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) RGD PMID:25589784 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604 		JBrowse link
G Smad3 SMAD family member 3 IDA rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO
ISS		 (PMID:19578371)
GO_REF:0000024		 RGD
UniProt		 PMID:19578371 GO_REF:0000024 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:17401695)
GO_REF:0000024		 RGD
AgBase		 PMID:17401695 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS		 (PMID:17401695)
GO_REF:0000024		 RGD
AgBase		 PMID:17401695 GO_REF:0000024 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO
IBA		 (PMID:20025746)
(MGI:4418582|PMID:20025746), (MGI:5700277|PMID:26207632)
PMID:21873635		 RGD PMID:20025746 PMID:26207632, PMID:21873635, PMID:21873635 MGI:4418582 MGI:5700277, RGD:13792537, RGD:13792537 NCBI chr12:48,598,498...48,605,704
Ensembl chr12:48,598,647...48,605,704 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (MGI:3574150|PMID:15728361) RGD PMID:15728361 MGI:3574150 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:17720811)
GO_REF:0000107		 RGD
Ensembl		 PMID:17720811 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) RGD PMID:21784188 MGI:5291888 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO MGI:3840841 (MGI:5514358|PMID:21490954) RGD PMID:21490954 MGI:5514358 NCBI chr 6:27,835,346...27,919,285
Ensembl chr 6:27,887,797...27,915,563 		JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5613837|PMID:25407797)
PMID:21873635		 UniProt
RGD		 PMID:25407797, PMID:21873635, PMID:21873635 GO_REF:0000024 MGI:5613837, RGD:13792537, RGD:13792537 NCBI chr14:21,282,488...21,301,966
Ensembl chr14:21,286,510...21,299,068 		JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO (MGI:3603472|PMID:16014627) RGD PMID:16014627 MGI:3603472 NCBI chr14:6,926,972...6,933,079
Ensembl chr14:6,926,976...6,933,070 		JBrowse link
G Enam enamelin acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3796583 (MGI:5647983|PMID:24603688)
PMID:21873635		 RGD PMID:24603688, PMID:21873635, PMID:21873635 MGI:5647983, RGD:13792537, RGD:13792537 NCBI chr14:21,194,635...21,219,529
Ensembl chr14:21,194,664...21,219,454 		JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISO
IBA
ISS		 (PMID:22901946)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:22901946, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr14:17,575,295...17,583,214
Ensembl chr14:17,575,758...17,582,823 		JBrowse link
positive regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfap2a transcription factor AP-2 alpha involved_in ISO
ISS		 (PMID:19578371)
GO_REF:0000024		 RGD
UniProt		 PMID:19578371 GO_REF:0000024 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457 		JBrowse link
G Wnt6 Wnt family member 6 involved_in ISO (PMID:20113781) RGD PMID:20113781 NCBI chr 9:82,033,543...82,047,172
Ensembl chr 9:82,033,543...82,047,166 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    positive regulation of biological process 6628
      positive regulation of biomineralization 54
        positive regulation of biomineral tissue development 53
          positive regulation of bone mineralization + 45
          positive regulation of shell calcification 0
          positive regulation of tooth mineralization + 6
Path 2
Term Annotations click to browse term
  biological_process 20082
    developmental process 6853
      anatomical structure development 6313
        multicellular organism development 5789
          system development 5317
            animal organ development 4068
              biomineral tissue development 172
                regulation of biomineral tissue development 101
                  positive regulation of biomineral tissue development 53
                    positive regulation of bone mineralization + 45
                    positive regulation of shell calcification 0
                    positive regulation of tooth mineralization + 6
paths to the root