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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of biomineral tissue development
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Accession:GO:0070168 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


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negative regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 involved_in ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G GAS6 growth arrest specific 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (PMID:22110751) BHF-UCL PMID:22110751 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G NOS3 nitric oxide synthase 3 involved_in ISO (PMID:23583836) BHF-UCL PMID:23583836 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr17:7,931,786...8,012,484
Ensembl chr17:7,934,739...8,178,707 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:8702833 GO_REF:0000033 GO_REF:0000107 RGD:1626074 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716 		JBrowse link
G BCOR BCL6 corepressor involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr  X:34,621,314...34,735,502
Ensembl chr  X:34,621,886...34,645,766 		JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:59,696,125...59,701,990
Ensembl chr17:59,696,477...59,701,744 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:22510396), (PMID:25479107), (PMID:30111653) UniProt PMID:22510396 PMID:25479107 PMID:30111653 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718 		JBrowse link
G FGF23 fibroblast growth factor 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:40,501,655...40,511,785
Ensembl chr27:40,501,731...40,509,766 		JBrowse link
G GATA1 GATA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15005853) Ensembl
MGI		 PMID:15005853 GO_REF:0000107 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17181398) Ensembl
MGI		 PMID:17181398 GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G LOC480600 chemokine (C-C motif) ligand 3 involved_in ISO (PMID:21403648) UniProt PMID:21403648 NCBI chr 9:37,708,561...37,710,209
Ensembl chr 9:37,676,966...37,710,209 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790802) Ensembl
MGI		 PMID:11790802 GO_REF:0000107 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433 		JBrowse link
G MEPE matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO (PMID:22766095)
(PMID:12421822), (PMID:15843468)		 MGI PMID:12421822 PMID:15843468 PMID:22766095 NCBI chr32:11,212,531...11,222,805
Ensembl chr32:11,212,531...11,222,805 		JBrowse link
G NFE2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chr27:1,003,551...1,010,514
Ensembl chr27:1,003,816...1,010,264 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371614) Ensembl
MGI		 PMID:11371614 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G SRGN serglycin involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:20,230,713...20,244,952
Ensembl chr 4:20,230,743...20,244,474 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346 		JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967 		JBrowse link
G RFLNA refilin A involved_in IBA GO_Central GO_REF:0000033 NCBI chr26:5,501,223...5,509,118
Ensembl chr26:5,502,106...5,505,458 		JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:24436304) Ensembl
MGI
GO_Central		 PMID:24436304 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:45,232,910...45,239,569
Ensembl chr 9:45,232,975...45,239,130 		JBrowse link
negative regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPN asporin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,881,610...98,905,641
Ensembl chr 1:98,881,690...98,904,945 		JBrowse link
G BCOR BCL6 corepressor involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr  X:34,621,314...34,735,502
Ensembl chr  X:34,621,886...34,645,766 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22117
    developmental process 6922
      negative regulation of developmental process 1078
        negative regulation of biomineral tissue development 30
          negative regulation of bone mineralization + 20
          negative regulation of shell calcification 0
          negative regulation of tooth mineralization + 2
Path 2
Term Annotations click to browse term
  biological_process 22117
    developmental process 6922
      anatomical structure development 6481
        tissue development 2265
          biomineral tissue development 187
            regulation of biomineral tissue development 107
              negative regulation of biomineral tissue development 30
                negative regulation of bone mineralization + 20
                negative regulation of shell calcification 0
                negative regulation of tooth mineralization + 2
paths to the root