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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of biomineral tissue development
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Accession:GO:0070168 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


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negative regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gas6 growth arrest specific 6 involved_in ISO
ISS
(PMID:20048160)
GO_REF:0000024
RGD
UniProt
PMID:20048160 GO_REF:0000024 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:6158885|PMID:23583836)
Ensembl
RGD
PMID:23583836 GO_REF:0000107 MGI:6158885 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108), (MGI:6158885|PMID:23583836) RGD PMID:23583836 PMID:26491108 MGI:6158728 MGI:6158885 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:4947506|PMID:20056916)
(PMID:22110751)
UniProt
RGD
PMID:20056916 PMID:22110751 GO_REF:0000024 MGI:4947506 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)
RGD PMID:26634652 MGI:5921830 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein involved_in IMP
ISO
ISS
(MGI:3687916|PMID:12556469)
GO_REF:0000024
RGD
UniProt
PMID:12556469, PMID:8702833 GO_REF:0000024 MGI:3687916, RGD:1626074 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Bcor BCL6 co-repressor involved_in ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:11,570,155...11,692,022
Ensembl chr  X:11,648,989...11,691,099
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISO
ISS
(PMID:11165938)
GO_REF:0000024
RGD
UniProt
PMID:11165938 GO_REF:0000024 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396)
UniProt
RGD
PMID:22510396 PMID:25479107 PMID:30111653 GO_REF:0000024 MGI:5607146 MGI:6220772 MGI:6294341 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:18282132) RGD PMID:18282132 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of_or_within ISO MGI:2177586 (MGI:3653541|PMID:15005853) RGD PMID:15005853 MGI:3653541 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:1857719 (MGI:3777866|PMID:17181398)
Ensembl
RGD
PMID:17181398 GO_REF:0000107 MGI:3777866 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (MGI:2178869|PMID:11790802) RGD PMID:11790802 MGI:2178869 NCBI chr 1:221,099,155...221,116,096
Ensembl chr 1:221,099,998...221,116,096
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO MGI:2448895 (MGI:2448336|PMID:12421822), (MGI:3851320|PMID:15843468), (MGI:5431257|PMID:22766095) RGD PMID:12421822 PMID:15843468 PMID:22766095 MGI:2448336 MGI:3851320 MGI:5431257 NCBI chr14:6,782,011...6,793,561
Ensembl chr14:6,782,012...6,793,558
JBrowse link
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO MGI:1857224 (MGI:3653541|PMID:15005853) RGD PMID:15005853 MGI:3653541 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:3713957|PMID:17537919)
UniProt
RGD
PMID:17537919 GO_REF:0000024 MGI:3713957 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2158693 (MGI:2135696|PMID:11371614) RGD PMID:11371614 MGI:2135696 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Srgn serglycin involved_in ISO
ISS
IBA
(PMID:16870619)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:16870619, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr20:32,120,317...32,158,071
Ensembl chr20:32,120,320...32,139,789
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23081848 RGD:10003033 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Pth parathyroid hormone involved_in IMP PMID:11604398 CAFA PMID:11604398, PMID:11604398 RGD:12793028, RGD:12793028 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Rflna refilin A involved_in
acts_upstream_of_or_within
ISO
IBA
MGI:1923816 (MGI:5570967|PMID:24436304)
PMID:21873635
RGD PMID:24436304, PMID:21873635, PMID:21873635 MGI:5570967, RGD:13792537, RGD:13792537 NCBI chr12:37,038,732...37,047,628
Ensembl chr12:37,038,733...37,047,628
JBrowse link
G Rflnb refilin B acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1920371 (MGI:5570967|PMID:24436304)
PMID:21873635
RGD PMID:24436304, PMID:21873635, PMID:21873635 MGI:5570967, RGD:13792537, RGD:13792537 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380
JBrowse link
negative regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspn asporin involved_in ISO (MGI:3722035|PMID:17522060) RGD PMID:17522060 MGI:3722035 NCBI chr17:14,655,958...14,681,355
Ensembl chr17:14,656,009...14,679,409
JBrowse link
G Bcor BCL6 co-repressor involved_in ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:11,570,155...11,692,022
Ensembl chr  X:11,648,989...11,691,099
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    negative regulation of biological process 5713
      negative regulation of biomineralization 30
        negative regulation of biomineral tissue development 29
          negative regulation of bone mineralization + 20
          negative regulation of shell calcification 0
          negative regulation of tooth mineralization + 2
Path 2
Term Annotations click to browse term
  biological_process 20082
    developmental process 6853
      anatomical structure development 6313
        multicellular organism development 5789
          system development 5317
            animal organ development 4068
              biomineral tissue development 172
                regulation of biomineral tissue development 101
                  negative regulation of biomineral tissue development 29
                    negative regulation of bone mineralization + 20
                    negative regulation of shell calcification 0
                    negative regulation of tooth mineralization + 2
paths to the root