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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of biomineral tissue development
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Accession:GO:0070167 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


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negative regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gas6 growth arrest specific 6 involved_in ISO
ISS		 (PMID:20048160)
GO_REF:0000024		 RGD
UniProt		 PMID:20048160 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6158885|PMID:23583836)		 Ensembl
RGD		 PMID:23583836 GO_REF:0000107 MGI:6158885 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108), (MGI:6158885|PMID:23583836) RGD PMID:23583836 PMID:26491108 MGI:6158728 MGI:6158885 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947506|PMID:20056916)
(PMID:22110751)		 UniProt
RGD		 PMID:20056916 PMID:22110751 GO_REF:0000024 MGI:4947506 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)		 RGD PMID:26634652 MGI:5921830 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein involved_in IMP
ISS
ISO		 GO_REF:0000024
(MGI:3687916|PMID:12556469)		 UniProt
RGD		 PMID:12556469 PMID:8702833 GO_REF:0000024 MGI:3687916, RGD:1626074 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999 		JBrowse link
G Bcor BCL6 co-repressor involved_in ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:123,589,997...123,613,767
Ensembl chr 8:123,589,621...123,612,687 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISO
IEA
ISS		 (PMID:11165938)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11165938 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396)		 UniProt
RGD		 PMID:22510396 PMID:25479107 PMID:30111653 GO_REF:0000024 MGI:5607146 MGI:6220772 MGI:6294341 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:18282132) RGD PMID:18282132 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of_or_within ISO MGI:2177586 (PMID:15005853) RGD PMID:15005853 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857719 (PMID:17181398)		 Ensembl
RGD		 PMID:17181398 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (PMID:11790802) RGD PMID:11790802 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975 		JBrowse link
G Mepe matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO MGI:2448895 (PMID:12421822), (PMID:15843468), (PMID:22766095) RGD PMID:12421822 PMID:15843468 PMID:22766095 NCBI chr14:5,420,634...5,432,186
Ensembl chr14:5,420,635...5,432,183 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO MGI:1857224 (PMID:15005853) RGD PMID:15005853 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:3713957|PMID:17537919)		 UniProt
RGD		 PMID:17537919 GO_REF:0000024 MGI:3713957 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2158693 (PMID:11371614) RGD PMID:11371614 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Srgn serglycin involved_in ISO
IBA
ISS		 (PMID:16870619)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:16870619 GO_REF:0000024 GO_REF:0000033 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23081848 RGD:10003033 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Pth parathyroid hormone involved_in IMP PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Rflna refilin A involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1923816 (PMID:24436304)		 GO_Central
RGD		 PMID:24436304 GO_REF:0000033 NCBI chr12:31,633,360...31,642,313
Ensembl chr12:31,633,361...31,642,317 		JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1920371 (PMID:24436304)		 GO_Central
RGD		 PMID:24436304 GO_REF:0000033 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976 		JBrowse link
negative regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspn asporin involved_in ISO (MGI:3722035|PMID:17522060) RGD PMID:17522060 MGI:3722035 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041 		JBrowse link
G Bcor BCL6 co-repressor involved_in ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613 		JBrowse link
positive regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISO (PMID:25407797) RGD PMID:25407797 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181 		JBrowse link
G Atf4 activating transcription factor 4 acts_upstream_of_or_within ISO MGI:2180373|MGI:3819270|MGI:5550363|MGI:5812282 (PMID:27812542) RGD PMID:27812542 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:27812542)
GO_REF:0000107		 RGD
Ensembl		 PMID:27812542 GO_REF:0000107 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:29850565) RGD PMID:29850565 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISS
ISO		 GO_REF:0000024
(PMID:22901946)		 UniProt
RGD		 PMID:22901946 GO_REF:0000024 NCBI chr14:16,071,835...16,080,151
Ensembl chr14:16,073,058...16,080,129 		JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA		 (PMID:18436533)
GO_REF:0000107		 RGD
Ensembl		 PMID:18436533 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in IEA
ISO		 GO_REF:0000107
(PMID:18436533)		 Ensembl
RGD		 PMID:18436533 GO_REF:0000107 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) RGD PMID:22419726 MGI:6211994 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688 		JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1859675 (PMID:15724149)		 Ensembl
RGD		 PMID:15724149 GO_REF:0000107 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6393219|PMID:24906289)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24906289 GO_REF:0000024 GO_REF:0000107 MGI:6393219 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)		 RGD PMID:25589784 MGI:5634871 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5780494|PMID:26392310)		 UniProt
Ensembl
RGD		 PMID:26392310 GO_REF:0000024 GO_REF:0000107 MGI:5780494 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor involved_in ISO (PMID:21723284) RGD PMID:21723284 NCBI chr 6:25,315,236...25,319,821 JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009350|PMID:20675382)
(PMID:18436533), (PMID:20576608)		 UniProt
RGD		 PMID:18436533 PMID:20576608 PMID:20675382 GO_REF:0000024 MGI:5009350 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 IDA
ISO
ISS
IEA		 (PMID:14749725)
GO_REF:0000024
(PMID:14749725), (PMID:18436533)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:14749725 PMID:18436533 PMID:15352071 GO_REF:0000024 GO_REF:0000107, RGD:9068399 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO
IEA		 (PMID:20675382)
GO_REF:0000107		 RGD
Ensembl		 PMID:20675382 GO_REF:0000107 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Cd276 Cd276 molecule acts_upstream_of_or_within ISO MGI:3033707 (PMID:15317945) RGD PMID:15317945 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:18434589 RGD:151665814 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) RGD PMID:17369251 PMID:22615579 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (PMID:20053668) RGD PMID:20053668 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4943600|PMID:21402791)		 UniProt
RGD		 PMID:21402791 GO_REF:0000024 MGI:4943600 NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398 		JBrowse link
G Gpm6b glycoprotein m6b involved_in ISS
ISO		 GO_REF:0000024
(PMID:21638316)		 UniProt
RGD		 PMID:21638316 GO_REF:0000024 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (MGI:4943600|PMID:21402791) RGD PMID:21402791 MGI:4943600 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Kl Klotho involved_in ISO
IEA		 (PMID:12110410)
GO_REF:0000107		 RGD
Ensembl		 PMID:12110410 GO_REF:0000107 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285459|PMID:21652706)		 UniProt
RGD		 PMID:21652706 GO_REF:0000024 MGI:5285459 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO MGI:5007248 (PMID:21606205) RGD PMID:21606205 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21723284)		 UniProt
RGD		 PMID:21723284 GO_REF:0000024 NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO UniProtKB:Q91ZD1 (MGI:4950000|PMID:21262216) RGD PMID:21262216 MGI:4950000 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in ISO UniProtKB:Q9WVG7 (MGI:4950000|PMID:21262216) RGD PMID:21262216 MGI:4950000 NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (PMID:12677010), (PMID:18519738) RGD PMID:12677010 PMID:18519738 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) RGD PMID:19097194 MGI:3813934 NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556 		JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP RGD PMID:10807497 RGD:1642474 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pth parathyroid hormone involved_in IDA
ISO		 (PMID:17696759) RGD PMID:17696759 PMID:15758479 PMID:22445539 RGD:7207452, RGD:7242906 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Ptn pleiotrophin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6294181|PMID:19442624)		 UniProt
Ensembl
RGD		 PMID:19442624 GO_REF:0000024 GO_REF:0000107 MGI:6294181 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G Slc20a2 solute carrier family 20 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6342320|PMID:30721528)		 UniProt
RGD		 PMID:30721528 GO_REF:0000024 MGI:6342320 NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO
IEA		 (PMID:25589784)
GO_REF:0000107		 RGD
Ensembl		 PMID:25589784 GO_REF:0000107 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Smad3 SMAD family member 3 IDA rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO (MGI:6717031|PMID:33882302) RGD PMID:33882302 MGI:6717031 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO
ISS		 (PMID:19578371)
GO_REF:0000024		 RGD
UniProt		 PMID:19578371 GO_REF:0000024 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO
IBA		 (PMID:20025746)
GO_REF:0000033
(MGI:4418582|PMID:20025746), (MGI:5700277|PMID:26207632)		 RGD
GO_Central		 PMID:20025746 PMID:26207632 GO_REF:0000033 MGI:4418582 MGI:5700277 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:15728361) RGD PMID:15728361 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:17720811) RGD PMID:17720811 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) RGD PMID:21784188 MGI:5291888 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO MGI:3840841 (PMID:21490954) RGD PMID:21490954 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
ISS		 (PMID:16433617)
GO_REF:0000024		 RGD
UniProt		 PMID:16433617 GO_REF:0000024 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISO
IBA
IEA
ISS		 (MGI:5613837|PMID:25407797)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000002
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
InterPro
UniProt		 PMID:25407797 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5613837 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO		 GO_REF:0000107
(MGI:6716964|PMID:26403673)		 Ensembl
RGD		 PMID:26403673 GO_REF:0000107 MGI:6716964 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO (PMID:16014627) RGD PMID:16014627 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Enam enamelin involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3796583 (PMID:24603688)		 GO_Central
RGD		 PMID:24603688 GO_REF:0000033 NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425 		JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISO
IBA
IEA
ISS		 (PMID:22901946)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:22901946 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:16,071,835...16,080,151
Ensembl chr14:16,073,058...16,080,129 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
positive regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfap2a transcription factor AP-2 alpha involved_in ISO
ISS		 (PMID:19578371)
GO_REF:0000024		 RGD
UniProt		 PMID:19578371 GO_REF:0000024 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Wnt6 Wnt family member 6 involved_in ISO (PMID:20113781) RGD PMID:20113781 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankh ANKH inorganic pyrophosphate transport regulator acts_upstream_of_or_within
involved_in		 TAS
ISO
IEA
ISS		 MGI:1856651 (PMID:10894769), (PMID:7276519)
(MGI:6448251|PMID:32639996)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:7276519 PMID:10894769 PMID:32639996 PMID:12861042 GO_REF:0000024 GO_REF:0000107 MGI:6448251, RGD:634632 NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bmp2k BMP-2 inducible kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:11500515)		 GO_Central
RGD		 PMID:11500515 GO_REF:0000033 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21350216)		 Ensembl
RGD		 PMID:21350216 GO_REF:0000107 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA		 (PMID:9415400)
GO_REF:0000107		 RGD
Ensembl		 PMID:9415400 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (PMID:20564243) RGD PMID:20564243 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 TAS RGD PMID:8509401 RGD:728616 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000118
(PMID:20138147)
GO_REF:0000033		 TreeGrafter
RGD
GO_Central		 PMID:20138147 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Fgf23 fibroblast growth factor 23 acts_upstream_of_or_within ISO MGI:3512143 (PMID:15579309) RGD PMID:15579309 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:2445468|MGI:3776013 (PMID:21346198) RGD PMID:21346198 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Matn1 matrilin 1 acts_upstream_of_or_within ISO MGI:2153042|MGI:3663272 (PMID:16877353) RGD PMID:16877353 NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059 		JBrowse link
G Mgp matrix Gla protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667 		JBrowse link
G Nbr1 NBR1, autophagy cargo receptor involved_in IEA
ISO		 GO_REF:0000107
(MGI:4818844|PMID:20616007)		 Ensembl
RGD		 PMID:20616007 GO_REF:0000107 MGI:4818844 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412 		JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase acts_upstream_of_or_within ISO (PMID:30622831) RGD PMID:30622831 NCBI chr10:105,933,245...105,940,327
Ensembl chr10:105,933,249...105,940,315 		JBrowse link
G Omd osteomodulin NAS RGD PMID:10607915 RGD:633418 NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3839226|PMID:19204730)		 UniProt
RGD		 PMID:19204730 GO_REF:0000024 MGI:3839226 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in ISO
IEA
ISS		 (PMID:30779713)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:30779713 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO MGI:1890508 (PMID:23695662) RGD PMID:23695662 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982 		JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 acts_upstream_of_or_within ISO MGI:1890508 (PMID:23695662) RGD PMID:23695662 NCBI chr  X:141,792,589...141,795,257 JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:19597909) RGD PMID:19597909 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Txlng taxilin gamma involved_in ISO (MGI:3587454|PMID:15911876), (MGI:5306578|PMID:19016261) RGD PMID:15911876 PMID:19016261 MGI:3587454 MGI:5306578 NCBI chr  X:31,864,111...31,912,931
Ensembl chr  X:31,864,111...31,912,926 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:1099440 (PMID:23695662) RGD PMID:23695662 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (PMID:20102707) RGD PMID:20102707 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16014627)		 Ensembl
RGD		 PMID:16014627 GO_REF:0000107 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of ISO MGI:7505608 (PMID:30243146), (PMID:31336344) RGD PMID:30243146 PMID:31336344 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      regulation of developmental process 2784
        regulation of multicellular organismal development 1674
          regulation of biomineral tissue development 106
            negative regulation of biomineral tissue development + 30
            positive regulation of biomineral tissue development + 56
            regulation of bone mineralization + 86
            regulation of shell calcification + 0
            regulation of tooth mineralization + 13
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          regulation of multicellular organismal development 1674
            regulation of biomineral tissue development 106
              negative regulation of biomineral tissue development + 30
              positive regulation of biomineral tissue development + 56
              regulation of bone mineralization + 86
              regulation of shell calcification + 0
              regulation of tooth mineralization + 13
paths to the root