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ONTOLOGY REPORT - ANNOTATIONS

Term:ubiquitin-dependent endocytosis
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Accession:GO:0070086 term browser browse the term
Definition:Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
Synonyms:exact_synonym: ubiquitin-mediated endocytosis


show annotations for term's descendants           Sort by:
ubiquitin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene involved_in ISO (PMID:15383614) RGD PMID:15383614 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 involved_in ISO (PMID:15383614) RGD PMID:15383614 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha involved_in ISO (PMID:22087322) RGD PMID:22087322 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:15256501) RGD PMID:15256501 NCBI chr 3:16,223,367...16,264,261
Ensembl chr 3:16,223,367...16,264,154 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:28675177) RGD PMID:28675177 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Neurl1b neuralized E3 ubiquitin protein ligase 1B involved_in ISO
IBA		 (MGI:3696936|PMID:17003037)
GO_REF:0000033		 RGD
GO_Central		 PMID:17003037 GO_REF:0000033 MGI:3696936 NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119 		JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649 		JBrowse link
positive regulation of ubiquitin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsg101 tumor susceptibility 101 involved_in ISO
IEA		 (MGI:5619493|PMID:11916981)
GO_REF:0000107		 RGD
Ensembl		 PMID:11916981 GO_REF:0000107 MGI:5619493 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554 		JBrowse link
G Vps28 VPS28 subunit of ESCRT-I involved_in ISO
IEA		 (PMID:11916981)
GO_REF:0000107		 RGD
Ensembl		 PMID:11916981 GO_REF:0000107 NCBI chr 7:108,341,989...108,345,837
Ensembl chr 7:108,341,989...108,345,837 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    cellular process 18524
      vesicle-mediated transport 1638
        endocytosis 735
          ubiquitin-dependent endocytosis 9
            negative regulation of ubiquitin-dependent endocytosis 0
            positive regulation of ubiquitin-dependent endocytosis 2
            regulation of ubiquitin-dependent endocytosis + 2
Path 2
Term Annotations click to browse term
  biological_process 20115
    localization 5683
      cellular localization 3691
        cellular macromolecule localization 2712
          protein localization 2700
            protein localization to organelle 1048
              establishment of protein localization to organelle 480
                ubiquitin-dependent endocytosis 9
                  negative regulation of ubiquitin-dependent endocytosis 0
                  positive regulation of ubiquitin-dependent endocytosis 2
                  regulation of ubiquitin-dependent endocytosis + 2
paths to the root