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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquitin-dependent endocytosis
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Accession:GO:0070086 term browser browse the term
Definition:Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
Synonyms:exact_synonym: ubiquitin-mediated endocytosis



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ubiquitin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10ra interleukin 10 receptor subunit alpha involved_in ISO (PMID:22087322) RGD PMID:22087322 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:15256501) RGD PMID:15256501 NCBI chr 3:16,223,367...16,264,261
Ensembl chr 3:16,223,367...16,264,154
JBrowse link
G Neurl1b neuralized E3 ubiquitin protein ligase 1B involved_in IBA
ISO
PMID:21873635
(MGI:3696936|PMID:17003037)
RGD PMID:17003037 PMID:21873635 MGI:3696936, RGD:13792537 NCBI chr10:16,758,097...16,784,943
Ensembl chr10:16,757,208...16,785,119
JBrowse link
positive regulation of ubiquitin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsg101 tumor susceptibility 101 involved_in ISO (MGI:5619493|PMID:11916981) RGD PMID:11916981 MGI:5619493 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554
JBrowse link
G Vps28 VPS28 subunit of ESCRT-I involved_in ISO
IEA
(PMID:11916981)
GO_REF:0000107
RGD
Ensembl
PMID:11916981 GO_REF:0000107 NCBI chr 7:108,341,989...108,345,837
Ensembl chr 7:108,341,989...108,345,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    localization 6554
      establishment of localization 4941
        establishment of protein localization 1723
          establishment of protein localization to organelle 470
            ubiquitin-dependent endocytosis 5
              negative regulation of ubiquitin-dependent endocytosis 0
              positive regulation of ubiquitin-dependent endocytosis 2
              regulation of ubiquitin-dependent endocytosis + 2
Path 2
Term Annotations click to browse term
  biological_process 19834
    localization 6554
      macromolecule localization 3064
        protein localization 2603
          cellular protein localization 1839
            protein localization to organelle 959
              establishment of protein localization to organelle 470
                ubiquitin-dependent endocytosis 5
                  negative regulation of ubiquitin-dependent endocytosis 0
                  positive regulation of ubiquitin-dependent endocytosis 2
                  regulation of ubiquitin-dependent endocytosis + 2
paths to the root