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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquitin-dependent endocytosis
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Accession:GO:0070086 term browser browse the term
Definition:Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
Synonyms:exact_synonym: ubiquitin-mediated endocytosis


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ubiquitin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10ra interleukin 10 receptor subunit alpha involved_in ISO (PMID:22087322) RGD PMID:22087322 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:15256501) RGD PMID:15256501 NCBI chr 3:11,970,401...12,009,463
Ensembl chr 3:11,972,813...12,007,570
JBrowse link
G Neurl1b neuralized E3 ubiquitin protein ligase 1B involved_in IBA
ISO
PMID:21873635
(MGI:3696936|PMID:17003037)
RGD PMID:17003037, PMID:21873635 MGI:3696936, RGD:13792537 NCBI chr10:17,048,251...17,075,139
Ensembl chr10:17,048,251...17,075,139
JBrowse link
positive regulation of ubiquitin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsg101 tumor susceptibility 101 involved_in ISO (MGI:5619493|PMID:11916981) RGD PMID:11916981 MGI:5619493 NCBI chr 1:102,941,151...102,971,017
Ensembl chr 1:102,941,231...102,970,950
JBrowse link
G Vps28 VPS28 subunit of ESCRT-I involved_in ISO
IEA
(PMID:11916981)
GO_REF:0000107
RGD
Ensembl
PMID:11916981 GO_REF:0000107 NCBI chr 7:117,684,339...117,688,187
Ensembl chr 7:117,684,339...117,688,187
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    cellular process 18481
      vesicle-mediated transport 1670
        endocytosis 695
          ubiquitin-dependent endocytosis 5
            negative regulation of ubiquitin-dependent endocytosis 0
            positive regulation of ubiquitin-dependent endocytosis 2
            regulation of ubiquitin-dependent endocytosis + 2
Path 2
Term Annotations click to browse term
  biological_process 19634
    localization 6435
      macromolecule localization 2988
        protein localization 2544
          cellular protein localization 1826
            protein localization to organelle 928
              establishment of protein localization to organelle 450
                ubiquitin-dependent endocytosis 5
                  negative regulation of ubiquitin-dependent endocytosis 0
                  positive regulation of ubiquitin-dependent endocytosis 2
                  regulation of ubiquitin-dependent endocytosis + 2
paths to the root