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ONTOLOGY REPORT - ANNOTATIONS


Term:all-trans retinoic acid 18-hydroxylase activity
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Accession:GO:0062183 term browser browse the term
Definition:Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
Synonyms:xref: RHEA:55856



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all-trans retinoic acid 18-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 enables ISO (PMID:22020119) RGD PMID:22020119 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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  molecular_function 20890
    catalytic activity 6118
      oxidoreductase activity 872
        monooxygenase activity 162
          all-trans retinoic acid 18-hydroxylase activity 2
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