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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of programmed necrotic cell death
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Accession:GO:0062098 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of programmed necrotic cell death.


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regulation of programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6275115|PMID:10974027)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:10974027 GO_REF:0000024 GO_REF:0000107 MGI:6275115 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
negative regulation of necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adprs ADP-ribosylserine hydrolase involved_in ISO (MGI:6445044|PMID:30830864) RGD PMID:30830864 MGI:6445044 NCBI chr 5:138,614,022...138,619,296
Ensembl chr 5:138,614,022...138,619,296 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:104798 (MGI:5315337|PMID:21052097)		 RGD PMID:21052097 PMID:21873635 MGI:5315337, RGD:13792537 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 involved_in IBA
ISO		 PMID:21873635
(MGI:5315337|PMID:21052097)		 RGD PMID:21052097 PMID:21873635 MGI:5315337, RGD:13792537 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:5796062 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp2 caspase 2 involved_in ISO (PMID:30025878) RGD PMID:30025878 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:31827280)
MGI:104798|MGI:1336166|MGI:1921506|MGI:2154952 (MGI:4947443|PMID:21368763), (MGI:5294742|PMID:21402742), (MGI:5306844|PMID:22037414), (MGI:5521568|PMID:22089168)
(MGI:6378798|PMID:31511692), (MGI:6401035|PMID:31748744), (MGI:6401044|PMID:31827281)
GO_REF:0000024		 RGD
UniProt		 PMID:21368763 PMID:21402742 PMID:22037414 PMID:22089168 PMID:31511692 More... GO_REF:0000024 MGI:4947443 MGI:5294742 MGI:5306844 MGI:5521568 MGI:6378798 MGI:6401035 MGI:6401044 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cav1 caveolin 1 involved_in ISO (MGI:5464050|PMID:23049990) RGD PMID:23049990 MGI:5464050 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator acts_upstream_of_or_within ISO MGI:104798|MGI:1261423|MGI:2154952 (MGI:4947443|PMID:21368763), (MGI:5486419|PMID:22675671), (MGI:5521568|PMID:22089168) RGD PMID:21368763 PMID:22089168 PMID:22675671 MGI:4947443 MGI:5486419 MGI:5521568 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Fadd Fas associated via death domain acts_upstream_of_or_within ISO MGI:104798|MGI:2154952 (MGI:5486419|PMID:22675671), (MGI:5521568|PMID:22089168) RGD PMID:22089168 PMID:22675671 MGI:5486419 MGI:5521568 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (MGI:5315337|PMID:21052097) RGD PMID:21052097 MGI:5315337 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mir101-2 microRNA 101-2 involved_in ISO (PMID:25910754) RGD PMID:25910754 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir101a microRNA 101a involved_in ISO (PMID:25910754) RGD PMID:25910754 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir214 microRNA 214 involved_in ISO (PMID:25910754) RGD PMID:25910754 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir22 microRNA 22 involved_in ISO (PMID:25910754) RGD PMID:25910754 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:25910754) RGD PMID:25910754 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mutyh mutY DNA glycosylase involved_in IEA
ISO		 GO_REF:0000107
(MGI:6378777|PMID:28059467)		 Ensembl
RGD		 PMID:28059467 GO_REF:0000107 MGI:6378777 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 involved_in ISO (PMID:29883609)
(MGI:6163945|PMID:29883609)		 RGD PMID:29883609 MGI:6163945 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104798 (MGI:5521568|PMID:22089168)		 Ensembl
RGD		 PMID:22089168 GO_REF:0000107 MGI:5521568 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:5602910|PMID:24813850), (MGI:5602911|PMID:24813849), (MGI:5907398|PMID:27819682), (MGI:5907399|PMID:27819681) RGD PMID:24813849 PMID:24813850 PMID:27819681 PMID:27819682 MGI:5602910 MGI:5602911 MGI:5907398 MGI:5907399 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Rnf31 ring finger protein 31 acts_upstream_of_or_within ISO MGI:104798 (MGI:5521568|PMID:22089168) RGD PMID:22089168 MGI:5521568 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16507998)		 Ensembl
RGD		 PMID:16507998 GO_REF:0000107 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22711822)		 Ensembl
RGD		 PMID:22711822 GO_REF:0000107 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161 		JBrowse link
negative regulation of programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS		 (PMID:30451898)
GO_REF:0000024		 RGD
UniProt		 PMID:30451898 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327 JBrowse link
positive regulation of necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2182480|PMID:12114629), (MGI:5430718|PMID:21467298)		 UniProt
RGD		 PMID:12114629 PMID:21467298 GO_REF:0000024 MGI:2182480 MGI:5430718 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Casp6 caspase 6 involved_in ISO
ISS		 (PMID:32298652)
GO_REF:0000024		 RGD
UniProt		 PMID:32298652 GO_REF:0000024 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Gzmb granzyme B IMP RGD PMID:19895873 RGD:2325193 NCBI chr15:30,343,361...30,346,792
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2182480|PMID:12114629), (MGI:3695559|PMID:17116882)		 UniProt
RGD		 PMID:12114629 PMID:17116882 GO_REF:0000024 MGI:2182480 MGI:3695559 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IMP
ISO		 (PMID:22028622), (PMID:22274400), (PMID:22817896) RGD PMID:22028622 PMID:22274400 PMID:22817896 PMID:23386613 PMID:22372834 RGD:7777171, RGD:7777172 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISO
ISS		 (PMID:22265414), (PMID:22817896)
(MGI:5315337|PMID:21052097), (MGI:5516181|PMID:22265414), (MGI:5602910|PMID:24813850), (MGI:5602911|PMID:24813849), (MGI:6434626|PMID:32296175), (MGI:6436371|PMID:22423968), (MGI:6436412|PMID:32200799), (MGI:6436434|PMID:27321907)
GO_REF:0000024		 RGD
UniProt		 PMID:21052097 PMID:22265414 PMID:22423968 PMID:22817896 PMID:24813849 More... GO_REF:0000024 MGI:5315337 MGI:5516181 MGI:5602910 MGI:5602911 MGI:6434626 MGI:6436371 MGI:6436412 MGI:6436434 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISO
ISS		 (PMID:32200799)
(MGI:5907398|PMID:27819682), (MGI:5907399|PMID:27819681), (MGI:6095612|PMID:29073079), (MGI:6434626|PMID:32296175), (MGI:6436371|PMID:22423968), (MGI:6436393|PMID:30050136), (MGI:6436412|PMID:32200799), (MGI:6436445|PMID:27746097), (MGI:6442612|PMID:27917412), (MGI:6453154|PMID:32350114), (MGI:6490907|PMID:33109609)
GO_REF:0000024		 RGD
UniProt		 PMID:22423968 PMID:27746097 PMID:27819681 PMID:27819682 PMID:27917412 More... GO_REF:0000024 MGI:5907398 MGI:5907399 MGI:6095612 MGI:6434626 MGI:6436371 MGI:6436393 MGI:6436412 MGI:6436445 MGI:6442612 MGI:6453154 MGI:6490907 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
positive regulation of programmed necrotic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (MGI:6140989|PMID:27258785) RGD PMID:27258785 MGI:6140989 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
regulation of necroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 involved_in ISO (PMID:21737330) RGD PMID:21737330 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 involved_in ISO (PMID:21737330) RGD PMID:21737330 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in ISO (PMID:21737330) RGD PMID:21737330 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO (PMID:27458237)
(MGI:5912943|PMID:28701375)		 RGD PMID:27458237 PMID:28701375 MGI:5912943 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Fadd Fas associated via death domain IMP RGD PMID:26038570 RGD:11341801 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Spata2 spermatogenesis associated 2 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5912943|PMID:28701375)
PMID:21873635
(PMID:27307491), (PMID:27458237), (PMID:27545878)		 UniProt
RGD		 PMID:27307491 PMID:27458237 PMID:27545878 PMID:28701375 PMID:21873635 GO_REF:0000024 MGI:5912943, RGD:13792537 NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    cellular process 18161
      cell death 2222
        regulation of cell death 1870
          regulation of necrotic cell death 51
            regulation of programmed necrotic cell death 34
              negative regulation of programmed necrotic cell death + 24
              positive regulation of programmed necrotic cell death + 8
              regulation of necroptotic process + 31
Path 2
Term Annotations click to browse term
  biological_process 19748
    biological regulation 13456
      regulation of biological process 13044
        regulation of cellular process 12253
          regulation of cell death 1870
            regulation of programmed cell death 1745
              regulation of programmed necrotic cell death 34
                negative regulation of programmed necrotic cell death + 24
                positive regulation of programmed necrotic cell death + 8
                regulation of necroptotic process + 31
paths to the root