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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cardiac epithelial to mesenchymal transition
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Accession:GO:0062043 term browser browse the term
Definition:Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


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positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Notch1 notch receptor 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3610266|PMID:16140292)
Ensembl
RGD
PMID:16140292 GO_REF:0000107 MGI:3610266 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Eng endoglin involved_in ISO (MGI:4368063|PMID:19703439) RGD PMID:19703439 MGI:4368063 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    multicellular organismal process 9082
      positive regulation of multicellular organismal process 1662
        positive regulation of epithelial to mesenchymal transition 50
          positive regulation of cardiac epithelial to mesenchymal transition 8
            positive regulation of endocardial cushion to mesenchymal transition + 1
            positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation 5
Path 2
Term Annotations click to browse term
  biological_process 20075
    developmental process 6842
      anatomical structure development 6313
        multicellular organism development 5789
          system development 5317
            animal organ development 4068
              mesenchyme development 298
                mesenchymal cell differentiation 238
                  epithelial to mesenchymal transition 156
                    cardiac epithelial to mesenchymal transition 38
                      regulation of cardiac epithelial to mesenchymal transition 11
                        positive regulation of cardiac epithelial to mesenchymal transition 8
                          positive regulation of endocardial cushion to mesenchymal transition + 1
                          positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation 5
paths to the root