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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of small molecule metabolic process
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Accession:GO:0062014 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
Synonyms:exact_synonym: negative regulation of small molecule metabolism



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negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139
JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242
JBrowse link
negative regulation of arginine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:179,231,712...179,348,759
Ensembl chr 1:183,580,773...183,639,882
JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr10:92,365,267...92,511,852
Ensembl chr10:95,828,094...95,983,257
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) BHF-UCL PMID:20165904 NCBI chr2B:116,265,529...116,517,557 JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIS1 fission, mitochondrial 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,381,058...93,386,483
Ensembl chr 7:106,621,211...106,626,683
JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:24,034,918...24,046,370
Ensembl chr22:42,233,619...42,244,930
JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23747249) Ensembl
MGI
PMID:23747249 GO_REF:0000107 NCBI chr11:64,794,157...64,800,512
Ensembl chr11:68,085,306...68,090,028
JBrowse link
G MALRD1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chr10:19,461,865...19,886,155 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA
RGD
Ensembl
PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942
JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583
JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chr10:1,056,280...1,062,070
Ensembl chr10:1,102,655...1,108,246
JBrowse link
G SOD1 superoxide dismutase 1 involved_in ISO (PMID:15473258) UniProt PMID:15473258 NCBI chr21:18,029,831...18,037,526 JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:85,930,638...85,932,065
Ensembl chr10:89,471,441...89,472,259
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:179,231,712...179,348,759
Ensembl chr 1:183,580,773...183,639,882
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139
JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242
JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847
JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chr 6:86,017,141...86,044,889 JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chr2B:6,309,048...6,314,660
Ensembl chr2B:119,887,728...119,892,986
JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5474727|PMID:23209793) ARUK-UCL
Ensembl
PMID:23209793 GO_REF:0000107 MGI:5474727 NCBI chr 1:39,244,438...39,259,156
Ensembl chr 1:40,569,706...40,584,438
JBrowse link
G PINK1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560
JBrowse link
G PLIN5 perilipin 5 involved_in ISO (MGI:5559662|PMID:22675471), (MGI:5559666|PMID:21885430)
(MGI:5440401|PMID:22532565)
UniProt PMID:21885430 PMID:22532565 PMID:22675471 MGI:5440401 MGI:5559662 MGI:5559666 NCBI chr19:3,542,675...3,555,611 JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:54,570,372...54,586,751
Ensembl chr12:57,161,781...57,172,705
JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (MGI:3526480|PMID:15639194) BHF-UCL PMID:15639194 MGI:3526480 NCBI chr2B:97,445,421...97,483,514
Ensembl chr2B:215,847,775...215,885,524
JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,249,717...7,255,165
Ensembl chr17:7,234,283...7,242,417
JBrowse link
G APOC1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460
JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037
JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942
JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583
JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16100574) Ensembl
MGI
PMID:16100574 GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012
JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16100574) Ensembl
MGI
PMID:16100574 GO_REF:0000107 NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647
JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,448,130...64,486,254
Ensembl chr15:83,670,090...83,671,859
JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:583,267...605,416
Ensembl chr20:359,879...375,486
JBrowse link
G UBR4 ubiquitin protein ligase E3 component n-recognin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,032,528...18,168,954
Ensembl chr 1:19,079,779...19,215,578
JBrowse link
G WDTC1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17767906) TreeGrafter
MGI
PMID:17767906 GO_REF:0000118 NCBI chr 1:26,487,185...26,560,974
Ensembl chr 1:27,554,268...27,616,429
JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin involved_in ISO (PMID:1184755) BHF-UCL PMID:1184755 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666
JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr17:34,934,452...35,121,195 JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847
JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (MGI:3526480|PMID:15639194) BHF-UCL PMID:15639194 MGI:3526480 NCBI chr2B:97,445,421...97,483,514
Ensembl chr2B:215,847,775...215,885,524
JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,249,717...7,255,165
Ensembl chr17:7,234,283...7,242,417
JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:102,755,388...102,818,686
Ensembl chr12:106,151,969...106,206,879
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr11:70,824,791...70,857,530
Ensembl chr11:74,126,169...74,158,854
JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24792439) Ensembl
MGI
PMID:24792439 GO_REF:0000107 NCBI chr 1:146,742,505...146,778,560
Ensembl chr 1:150,456,729...150,492,527
JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24792439) Ensembl
MGI
PMID:24792439 GO_REF:0000107 NCBI chr 1:146,678,858...146,704,831
Ensembl chr 1:150,393,061...150,417,295
JBrowse link
G FMO4 flavin containing dimethylaniline monoxygenase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24792439) Ensembl
MGI
PMID:24792439 GO_REF:0000107 NCBI chr 1:146,806,413...146,834,315
Ensembl chr 1:150,520,375...150,548,270
JBrowse link
G SIRT4 sirtuin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:117,867,453...117,887,968
Ensembl chr12:121,241,112...121,261,777
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISO (MGI:6414737|PMID:32103177) UniProt PMID:32103177 MGI:6414737 NCBI chr17:66,028,737...66,034,122 JBrowse link
negative regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11479628) Ensembl
MGI
PMID:11479628 GO_REF:0000107 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G C1QTNF12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22275362) Ensembl
MGI
TreeGrafter
PMID:22275362 GO_REF:0000107 GO_REF:0000118 Ensembl chr 1:1,200,756...1,205,301 JBrowse link
G C1QTNF3 C1q and TNF related 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20952387) UniProt
MGI
PMID:20952387 NCBI chr 5:76,292,679...76,325,064
Ensembl chr 5:81,687,891...81,742,003
JBrowse link
G CLK2 CDC like kinase 2 involved_in ISO (MGI:4429735|PMID:20074525) UniProt PMID:20074525 MGI:4429735 NCBI chr 1:130,607,877...130,618,461
Ensembl chr 1:134,213,237...134,221,288
JBrowse link
G CRY1 cryptochrome circadian regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:104,558,874...104,658,833
Ensembl chr12:107,954,262...108,052,484
JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604
JBrowse link
G GCK glucokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751
JBrowse link
G IL6 interleukin 6 ISO In liver RGD PMID:16308834 RGD:2306940 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G INS insulin involved_in ISO (PMID:8069456) AgBase PMID:8069456 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666
JBrowse link
G KAT2A lysine acetyltransferase 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,194,414...15,202,818
Ensembl chr17:15,416,075...15,424,197
JBrowse link
G LEPR leptin receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24051374) Ensembl
MGI
PMID:24051374 GO_REF:0000107 NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768
JBrowse link
G MST1 macrophage stimulating 1 involved_in ISO (PMID:19720831) UniProt PMID:19720831 NCBI chr 3:49,616,339...49,621,749 JBrowse link
G MTCL2 microtubule crosslinking factor 2 involved_in ISO (MGI:4837302|PMID:20813965) UniProt PMID:20813965 MGI:4837302 NCBI chr20:33,108,735...33,194,788
Ensembl chr20:34,227,625...34,311,338
JBrowse link
G PGP phosphoglycolate phosphatase involved_in ISO PMID:26755581
(PMID:26755581)
UniProt PMID:26755581 RGD:10679995 NCBI chr16:1,070,291...1,073,123 JBrowse link
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22837305) Ensembl
MGI
PMID:22837305 GO_REF:0000107 NCBI chr14:75,110,414...75,141,569
Ensembl chr14:94,442,931...94,473,779
JBrowse link
G SIK1 salt inducible kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,675,040...29,689,408
Ensembl chr21:42,975,920...42,987,948
JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126
JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO RGD PMID:21901280 RGD:152995490 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281
JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146
JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr2B:59,071,123...59,297,327
Ensembl chr2B:176,532,940...176,641,894
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20935145) Ensembl
MGI
PMID:20935145 GO_REF:0000107 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20935145) Ensembl
MGI
PMID:20935145 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATCAY ATCAY kinesin light chain interacting caytaxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,905,615...2,953,079
Ensembl chr19:3,854,423...3,900,175
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429
JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:69,592,293...69,662,321
Ensembl chr16:89,246,545...89,347,435
JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20176937) Ensembl
MGI
PMID:20176937 GO_REF:0000107 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:65,695,082...65,731,628
Ensembl chr 9:93,825,150...93,860,968
JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160
JBrowse link
G GIT1 GIT ArfGAP 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857
JBrowse link
G HDAC4 histone deacetylase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054
JBrowse link
G IER3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:19096392) MGI PMID:19096392 NCBI chr 6:30,488,162...30,489,784 JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chr11:47,566,884...47,596,711
Ensembl chr11:48,115,774...48,146,312
JBrowse link
G MYOG myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chr 1:178,684,933...178,687,971
Ensembl chr 1:182,979,700...182,982,611
JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr17:34,934,452...35,121,195 JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:29,015,155...29,016,987 JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in IEA Ensembl GO_REF:0000107 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chr11:106,484,913...106,613,711
Ensembl chr11:110,329,237...110,453,543
JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22891351) Ensembl
MGI
PMID:22891351 GO_REF:0000107 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20935145) Ensembl
MGI
TreeGrafter
PMID:20935145 GO_REF:0000107 GO_REF:0000118 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
G TRIM63 tripartite motif containing 63 involved_in ISO (PMID:34244144) FlyBase PMID:34244144 NCBI chr 1:25,309,949...25,373,658
Ensembl chr 1:26,378,373...26,392,041
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100987323 serine/threonine-protein phosphatase 2A catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:106,374,539...106,376,511 JBrowse link
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:47,143,081...47,209,034
Ensembl chr  X:55,374,807...55,441,024
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,099,605...30,126,917
Ensembl chr 8:27,288,263...27,302,606
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205
JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18698006) Ensembl
MGI
PMID:18698006 GO_REF:0000107 NCBI chr17:13,131,851...13,150,872
Ensembl chr17:13,302,796...13,317,312
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 1:32,176,465...32,185,133
Ensembl chr 1:33,363,673...33,371,524
JBrowse link
negative regulation of inositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISYNA1 inositol-3-phosphate synthase 1 involved_in ISO PMID:19188364 UniProt PMID:19188364 RGD:153298950 NCBI chr19:17,913,400...17,916,789
Ensembl chr19:18,884,412...18,887,931
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLEK pleckstrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:7535379 RGD:7777104 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882
JBrowse link
negative regulation of nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDA cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,538,696...19,568,008
Ensembl chr 1:20,583,441...20,612,711
JBrowse link
negative regulation of ornithine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OAZ1 ornithine decarboxylase antizyme 1 ISO RGD PMID:8166639 RGD:401851045 NCBI chr19:1,279,139...1,283,079
Ensembl chr19:2,250,678...2,254,179
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:72,630,064...72,650,918
Ensembl chr 9:100,624,151...100,638,597
JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIBF1 progesterone immunomodulatory binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:54,011,239...54,247,952
Ensembl chr13:72,788,608...73,022,473
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in IEA UniProt
Ensembl
GO_REF:0000104 GO_REF:0000107 NCBI chr2B:24,958,661...25,019,901
Ensembl chr2B:138,918,281...138,978,407
JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812
JBrowse link
G PRMT3 protein arginine methyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,412,419...20,538,295
Ensembl chr11:20,324,196...20,449,681
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,375,301...46,389,822
Ensembl chr19:55,301,955...55,313,690
JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,321,075...46,328,865
Ensembl chr20:47,384,818...47,390,733
JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:45,341,857...45,345,544
Ensembl chr 8:42,723,971...42,730,904
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      negative regulation of metabolic process 2932
        negative regulation of small molecule metabolic process 110
          negative regulation of (R)-mevalonic acid biosynthetic process 0
          negative regulation of L-dopa biosynthetic process 0
          negative regulation of L-glutamine biosynthetic process 0
          negative regulation of L-leucine biosynthetic process 0
          negative regulation of UDP-N-acetylglucosamine biosynthetic process 0
          negative regulation of UDP-glucose catabolic process 0
          negative regulation of acetate catabolic process 0
          negative regulation of aflatoxin biosynthetic process 0
          negative regulation of alcohol biosynthetic process + 12
          negative regulation of aldosterone metabolic process + 4
          negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 0
          negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
          negative regulation of arginine catabolic process 1
          negative regulation of asperthecin biosynthetic process 0
          negative regulation of bile acid metabolic process + 3
          negative regulation of cellular alcohol catabolic process 0
          negative regulation of cellular glucuronidation 0
          negative regulation of cholesterol metabolic process + 6
          negative regulation of citrulline biosynthetic process 1
          negative regulation of cordyol C biosynthetic process 0
          negative regulation of diorcinol biosynthetic process 0
          negative regulation of ecdysteroid metabolic process + 0
          negative regulation of emericellamide biosynthetic process + 0
          negative regulation of emodin biosynthetic process 0
          negative regulation of endocrocin biosynthetic process 0
          negative regulation of fatty acid metabolic process + 34
          negative regulation of ferulate catabolic process 0
          negative regulation of fumagillin biosynthetic process 0
          negative regulation of fumonisin biosynthetic process 0
          negative regulation of gamma-aminobutyric acid catabolic process 0
          negative regulation of gerfelin biosynthetic process 0
          negative regulation of gibberellin biosynthetic process 0
          negative regulation of gluconeogenesis 19
          negative regulation of glucose catabolic process to lactate via pyruvate 3
          negative regulation of glutamate metabolic process + 1
          negative regulation of glycolytic fermentation to ethanol 0
          negative regulation of glyoxylate cycle 0
          negative regulation of helvolic acid biosynthetic process 0
          negative regulation of histidine biosynthetic process 0
          negative regulation of homoserine biosynthetic process 0
          negative regulation of indoleacetic acid biosynthetic process via tryptophan 0
          negative regulation of lysine biosynthetic process via aminoadipic acid + 0
          negative regulation of methane biosynthetic process from formic acid 0
          negative regulation of monodictyphenone biosynthetic process 0
          negative regulation of naphtho-gamma-pyrone biosynthetic process 0
          negative regulation of nucleoside metabolic process 0
          negative regulation of nucleotide metabolic process + 34
          negative regulation of o-orsellinic acid biosynthetic process 0
          negative regulation of ornithine catabolic process 1
          negative regulation of penicillin metabolic process + 0
          negative regulation of progesterone biosynthetic process + 1
          negative regulation of proline metabolic process + 0
          negative regulation of pseurotin A biosynthetic process 0
          negative regulation of purine nucleobase metabolic process 0
          negative regulation of pyrimidine nucleobase metabolic process 0
          negative regulation of quinolinate biosynthetic process 1
          negative regulation of sarcinapterin metabolic process + 0
          negative regulation of selenocysteine metabolic process 0
          negative regulation of sulfur amino acid metabolic process + 0
          negative regulation of tatiopterin metabolic process + 0
          negative regulation of tensidol A biosynthetic process 0
          negative regulation of tensidol B biosynthetic process 0
          negative regulation of testosterone biosynthetic process 2
          negative regulation of ubiquinone biosynthetic process 0
          negative regulation of urea catabolic process 0
          negative regulation of violaceol I biosynthetic process 0
          negative regulation of violaceol II biosynthetic process 0
          negative regulation of vitamin metabolic process + 4
          negative regulation of xanthone-containing compound biosynthetic process + 0
          negative regulation of xylose catabolic process to ethanol 0
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        regulation of metabolic process 6171
          regulation of small molecule metabolic process 359
            negative regulation of small molecule metabolic process 110
              negative regulation of (R)-mevalonic acid biosynthetic process 0
              negative regulation of L-dopa biosynthetic process 0
              negative regulation of L-glutamine biosynthetic process 0
              negative regulation of L-leucine biosynthetic process 0
              negative regulation of UDP-N-acetylglucosamine biosynthetic process 0
              negative regulation of UDP-glucose catabolic process 0
              negative regulation of acetate catabolic process 0
              negative regulation of aflatoxin biosynthetic process 0
              negative regulation of alcohol biosynthetic process + 12
              negative regulation of aldosterone metabolic process + 4
              negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 0
              negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
              negative regulation of arginine catabolic process 1
              negative regulation of asperthecin biosynthetic process 0
              negative regulation of bile acid metabolic process + 3
              negative regulation of cellular alcohol catabolic process 0
              negative regulation of cellular glucuronidation 0
              negative regulation of cholesterol metabolic process + 6
              negative regulation of citrulline biosynthetic process 1
              negative regulation of cordyol C biosynthetic process 0
              negative regulation of diorcinol biosynthetic process 0
              negative regulation of ecdysteroid metabolic process + 0
              negative regulation of emericellamide biosynthetic process + 0
              negative regulation of emodin biosynthetic process 0
              negative regulation of endocrocin biosynthetic process 0
              negative regulation of fatty acid metabolic process + 34
              negative regulation of ferulate catabolic process 0
              negative regulation of fumagillin biosynthetic process 0
              negative regulation of fumonisin biosynthetic process 0
              negative regulation of gamma-aminobutyric acid catabolic process 0
              negative regulation of gerfelin biosynthetic process 0
              negative regulation of gibberellin biosynthetic process 0
              negative regulation of gluconeogenesis 19
              negative regulation of glucose catabolic process to lactate via pyruvate 3
              negative regulation of glutamate metabolic process + 1
              negative regulation of glycolytic fermentation to ethanol 0
              negative regulation of glyoxylate cycle 0
              negative regulation of helvolic acid biosynthetic process 0
              negative regulation of histidine biosynthetic process 0
              negative regulation of homoserine biosynthetic process 0
              negative regulation of indoleacetic acid biosynthetic process via tryptophan 0
              negative regulation of lysine biosynthetic process via aminoadipic acid + 0
              negative regulation of methane biosynthetic process from formic acid 0
              negative regulation of monodictyphenone biosynthetic process 0
              negative regulation of naphtho-gamma-pyrone biosynthetic process 0
              negative regulation of nucleoside metabolic process 0
              negative regulation of nucleotide metabolic process + 34
              negative regulation of o-orsellinic acid biosynthetic process 0
              negative regulation of ornithine catabolic process 1
              negative regulation of penicillin metabolic process + 0
              negative regulation of progesterone biosynthetic process + 1
              negative regulation of proline metabolic process + 0
              negative regulation of pseurotin A biosynthetic process 0
              negative regulation of purine nucleobase metabolic process 0
              negative regulation of pyrimidine nucleobase metabolic process 0
              negative regulation of quinolinate biosynthetic process 1
              negative regulation of sarcinapterin metabolic process + 0
              negative regulation of selenocysteine metabolic process 0
              negative regulation of sulfur amino acid metabolic process + 0
              negative regulation of tatiopterin metabolic process + 0
              negative regulation of tensidol A biosynthetic process 0
              negative regulation of tensidol B biosynthetic process 0
              negative regulation of testosterone biosynthetic process 2
              negative regulation of ubiquinone biosynthetic process 0
              negative regulation of urea catabolic process 0
              negative regulation of violaceol I biosynthetic process 0
              negative regulation of violaceol II biosynthetic process 0
              negative regulation of vitamin metabolic process + 4
              negative regulation of xanthone-containing compound biosynthetic process + 0
              negative regulation of xylose catabolic process to ethanol 0
paths to the root