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ONTOLOGY REPORT - ANNOTATIONS


Term:selective autophagy
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Accession:GO:0061912 term browser browse the term
Definition:The macroautophagy process in which specific structures are targeted by the autophagy process.


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selective autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sqstm1 sequestosome 1 involved_in ISO (PMID:22622177) UniProt PMID:22622177 NCBI chrNW_004936739:943,080...955,296 JBrowse link
aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acbd5 acyl-CoA binding domain containing 5 NOT|involved_in ISO (PMID:24535825) UniProt PMID:24535825 NCBI chrNW_004936484:2,224,308...2,268,302 JBrowse link
G Atg5 autophagy related 5 involved_in ISO (PMID:22982048)
(MGI:5751672|PMID:22982048)
ParkinsonsUK-UCL PMID:22982048 MGI:5751672 NCBI chrNW_004936564:2,759,085...2,885,394 JBrowse link
G LOC101974150 WD repeat and FYVE domain-containing protein 3 involved_in ISO (PMID:20168092), (PMID:20417604) UniProt PMID:20168092 PMID:20417604 NCBI chrNW_004936738:31,426...150,463 JBrowse link
G Map1lc3c microtubule associated protein 1 light chain 3 gamma involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chrNW_004936526:8,492,840...8,497,028 JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chrNW_004936739:943,080...955,296 JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISO (PMID:21143716) UniProt PMID:21143716 NCBI chrNW_004936828:543,651...588,673 JBrowse link
G Wdr81 WD repeat domain 81 involved_in ISO (PMID:28404643) UniProt PMID:28404643 NCBI chrNW_004936538:7,856,263...7,868,249 JBrowse link
glycophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stbd1 starch binding domain 1 involved_in ISO (PMID:20810658) GO_Central PMID:20810658 NCBI chrNW_004936676:300,244...304,206 JBrowse link
lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aup1 AUP1 lipid droplet regulating VLDL assembly factor involved_in ISO (PMID:29902443) UniProt PMID:29902443 NCBI chrNW_004936556:738,946...742,049 JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (MGI:5689086|PMID:23708524) GO_Central PMID:23708524 MGI:5689086 NCBI chrNW_004936798:297,600...304,929 JBrowse link
mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:25215947)
(PMID:21753002)
ParkinsonsUK-UCL PMID:21753002 PMID:25215947 NCBI chrNW_004936562:2,493,823...2,676,868 JBrowse link
G Atg13 autophagy related 13 involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chrNW_004936562:2,424,398...2,473,103 JBrowse link
G Atg14 autophagy related 14 involved_in ISO (PMID:23878393) ParkinsonsUK-UCL PMID:23878393 NCBI chrNW_004936495:155,709...195,860 JBrowse link
G Becn1 beclin 1 involved_in ISO (PMID:23878393) ParkinsonsUK-UCL PMID:23878393 NCBI chrNW_004936490:17,518,100...17,531,126 JBrowse link
G Gba glucosylceramidase beta acts_upstream_of_or_within ISO (MGI:5501380|PMID:23707074) MGI PMID:23707074 MGI:5501380 NCBI chrNW_004936580:4,715,869...4,720,752 JBrowse link
G Phb2 prohibitin 2 involved_in ISO (PMID:28017329)
(MGI:6436385|PMID:28017329)
UniProt PMID:28017329 MGI:6436385 NCBI chrNW_004936709:854,493...859,182 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within
ISO (PMID:28017329)
(MGI:5603233|PMID:24949970)
UniProt
MGI
PMID:24949970 PMID:28017329 MGI:5603233 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Retreg1 reticulophagy regulator 1 acts_upstream_of_or_within ISO (MGI:6370289|PMID:31446166) MGI PMID:31446166 MGI:6370289 NCBI chrNW_004936480:19,114,753...19,253,346 JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chrNW_004936739:943,080...955,296 JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:33096711)
(MGI:6450300|PMID:25919711)
UniProt PMID:25919711 PMID:33096711 MGI:6450300 NCBI chrNW_004936809:1,160,265...1,168,956 JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chrNW_004936660:2,160,394...2,188,848 JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chrNW_004936530:9,089,478...9,264,563 JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chrNW_004936646:605,302...630,645 JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chrNW_004936606:4,518,525...4,540,109 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:5319065|PMID:22044588) MGI PMID:22044588 MGI:5319065 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Usp30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chrNW_004936769:874,188...902,690 JBrowse link
negative regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 involved_in ISO (MGI:5581539|PMID:24709290) ParkinsonsUK-UCL PMID:24709290 MGI:5581539 NCBI chrNW_004936556:741,718...746,016 JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO (PMID:26942284) ParkinsonsUK-UCL PMID:26942284 NCBI chrNW_004936471:22,661,899...22,842,144 JBrowse link
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chrNW_004936721:757,500...778,416 JBrowse link
G Mfn2 mitofusin 2 involved_in ISO (MGI:5498413|PMID:23620051) ParkinsonsUK-UCL PMID:23620051 MGI:5498413 NCBI chrNW_004936474:767,754...795,258 JBrowse link
G Optn optineurin involved_in ISO (PMID:25294927) ParkinsonsUK-UCL PMID:25294927 NCBI chrNW_004937104:73,340...113,179 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:19029340) ParkinsonsUK-UCL PMID:19029340 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (MGI:5298125|PMID:22020285) ParkinsonsUK-UCL PMID:22020285 MGI:5298125 NCBI chrNW_004936750:1,381,864...1,406,736 JBrowse link
pexophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pjvk pejvakin involved_in ISO (MGI:6294584|PMID:30936319) UniProt PMID:30936319 MGI:6294584 NCBI chrNW_004936509:7,670,557...7,677,480 JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chrNW_004936486:8,985,871...9,007,461 JBrowse link
G Hspb8 heat shock protein family B (small) member 8 involved_in ISO (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chrNW_004936668:1,496,600...1,505,650 JBrowse link
G LOC101966195 huntingtin involved_in ISO (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chrNW_004936477:20,443,101...20,577,167 JBrowse link
positive regulation of lipophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO (PMID:23708524) GO_Central PMID:23708524 NCBI chrNW_004936504:5,985,407...5,987,453 JBrowse link
G LOC101966195 huntingtin involved_in ISO (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chrNW_004936477:20,443,101...20,577,167 JBrowse link
G LOC101967158 serine palmitoyltransferase 2 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chrNW_004936488:6,313,189...6,404,425 JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within ISO (MGI:5444071|PMID:22958918) MGI PMID:22958918 MGI:5444071 NCBI chrNW_004936474:12,416,652...12,436,799 JBrowse link
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chrNW_004936796:886,946...948,254 JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) UniProt PMID:22922758 NCBI chrNW_004936596:2,442,978...2,467,184 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:28608965 RGD:13432560 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chrNW_004936554:4,130,461...4,135,046 JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chrNW_004936479:10,432,172...10,435,154 JBrowse link
G Vdac1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chrNW_004936647:1,220,075...1,249,579 JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) UniProt PMID:29307555 NCBI chrNW_004936474:955,081...1,194,200 JBrowse link
positive regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in ISO (MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:5607224 NCBI chrNW_004936659:711,165...721,207 JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO (MGI:5616310|PMID:20457763) ParkinsonsUK-UCL PMID:20457763 MGI:5616310 NCBI chrNW_004936721:757,500...778,416 JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) CACAO PMID:30217973 NCBI chrNW_004936751:478,978...622,818 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chrNW_004936474:6,574,471...6,589,478 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:20457763)
(PMID:20871098), (PMID:23212910)
ParkinsonsUK-UCL PMID:20457763 PMID:20871098 PMID:23212910 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chrNW_004936478:30,787...36,952 JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:23245322) GO_Central PMID:23245322 NCBI chrNW_004936487:15,181,009...15,217,952 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004936478:6,717,354...6,768,293 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Optn optineurin involved_in ISO (PMID:21617041) ParkinsonsUK-UCL PMID:21617041 NCBI chrNW_004937104:73,340...113,179 JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004936544:3,606,925...3,653,248 JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (MGI:5645201|PMID:21617041) ParkinsonsUK-UCL PMID:21617041 MGI:5645201 NCBI chrNW_004936545:2,763,755...2,809,229 JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:5299952|PMID:22033934) MGI PMID:22033934 MGI:5299952 NCBI chrNW_004936576:522,234...531,660 JBrowse link
reticulophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chrNW_004936485:15,516,348...15,526,380 JBrowse link
G Rb1cc1 RB1 inducible coiled-coil 1 acts_upstream_of_or_within ISO (MGI:6323456|PMID:31006538) MGI PMID:31006538 MGI:6323456 NCBI chrNW_004936590:260,685...335,143 JBrowse link
G Retreg1 reticulophagy regulator 1 involved_in ISO (PMID:26040720)
(MGI:5646045|PMID:26040720)
GO_Central PMID:26040720 MGI:5646045 NCBI chrNW_004936480:19,114,753...19,253,346 JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (MGI:5925643|PMID:29056340) UniProt PMID:29056340 MGI:5925643 NCBI chrNW_004936531:8,555,966...8,562,829 JBrowse link
G Tex264 testis expressed 264, ER-phagy receptor involved_in
acts_upstream_of_or_within
ISO (PMID:31006537), (PMID:31006538)
(PMID:31006538)
GO_Central
MGI
PMID:31006537 PMID:31006538 NCBI chrNW_004936529:3,008,355...3,039,537 JBrowse link
G Uba5 ubiquitin like modifier activating enzyme 5 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chrNW_004936529:5,997,459...6,010,776 JBrowse link
G Ufc1 ubiquitin-fold modifier conjugating enzyme 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chrNW_004936903:449,042...462,727 JBrowse link
G Ufl1 UFM1 specific ligase 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chrNW_004936699:1,131,385...1,163,310 JBrowse link
G Ufm1 ubiquitin fold modifier 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chrNW_004937057:143,001...153,873 JBrowse link
xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg16l1 autophagy related 16 like 1 acts_upstream_of_or_within ISO (MGI:5605433|PMID:24954904) MGI PMID:24954904 MGI:5605433 NCBI chrNW_004936525:3,973,574...4,010,442 JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 involved_in ISO (PMID:25771791) GO_Central PMID:25771791 NCBI chrNW_004936490:12,576,752...12,609,273 JBrowse link
G Lgals8 galectin 8 involved_in ISO (PMID:22246324), (PMID:28077878) GO_Central PMID:22246324 PMID:28077878 NCBI chrNW_004936484:16,357,433...16,374,675 JBrowse link
G Wipi2 WD repeat domain, phosphoinositide interacting 2 acts_upstream_of_or_within ISO (MGI:5605433|PMID:24954904) MGI PMID:24954904 MGI:5605433 NCBI chrNW_004936765:909,118...946,788 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12164
    cellular process 11361
      process utilizing autophagic mechanism 365
        autophagy 365
          macroautophagy 200
            selective autophagy 67
              aggrephagy + 10
              glycophagy 1
              lipophagy + 7
              lysophagy 0
              mitophagy + 31
              pexophagy 1
              reticulophagy + 9
              ribophagy 0
              xenophagy + 12
Path 2
Term Annotations click to browse term
  biological_process 12164
    metabolic process 7639
      catabolic process 1703
        cellular catabolic process 1487
          autophagy 365
            macroautophagy 200
              selective autophagy 67
                aggrephagy + 10
                glycophagy 1
                lipophagy + 7
                lysophagy 0
                mitophagy + 31
                pexophagy 1
                reticulophagy + 9
                ribophagy 0
                xenophagy + 12
paths to the root